Gene F21A3.11 in Caenorhabditis elegans

Synonym: CELE_F18E2.11, F18E2.11

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP065_AA protein Get Run
CeleP065_AA_151-353 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PhoD PhoD-like phosphatase 103-201 2.6e-12 37.4 Pfam-A 58-159 (453) alignment
Range on Protein: 103-201
Range on HMM: 58-159/453.0
SVWRYIHRVNLTGLVPGTRYFYHVGSD--HGWSPIFFFTALKEREDGGFIYAVYGDLGVENGRsLGHIQKMAQKGQLDMVLHVGDFAYNMDE--SNGETG
| . |. .|..||| ||..|||.. ..  .  ||.  .. |.|..   .  ||...  .|.|      ...|.| .||.|||.||. |.  |   . |. 
serdytvkvevtgLepgqeyfYrfraeegesespvGrtrTlpeaaveslrlavvSCsnyeqGy.fnayrelaekedlDfvlhlGDyiYeygegtykneer

DEF
.| 
eek

PAPL 152-353 9.2e-67 216.9 In-house 1-194 (194) alignment
Range on Protein: 152-353
Range on HMM: 1-194/194.0
AVYGDLGVENGRSLGHIQKMAQKGQLDMVLHVGDFAYNMDESNGETGDEFFRQIEPVAGYIPYMATVGNHEYYNNFTHYVNRFTMPNSEHNLFYSYDVGP
||.|||| .| .||  .||..|||..|..|||||.||..||.|...||||.|||||.| ..|||...||||. .||..|..||.||.||.. ..|.. |.
avfGDlGqtnasslkrlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeeynfsnykarfsmpgseegesnssesgs

VHFVVFSTEFYFYTQWGYHQ-MENQYNWLINDLKKANSNRHNIPWIITMGHRPMYCSDFDGDDCTKYESvirtglpltHGYALEKLFYEYGVDVELWAHE
 .. . ..  .|.... ...  |.. ..  .....|. || . ||||.|||||||||. | |||.. ..         . .|||.|.|.||||..|..||
nsysfetesvhfivlsseedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdkddckekak.........mlaaledllykygVDlvlaGHe

HSY
|||
HsY

Metallophos Calcineurin-like phosphoesterase 152-353 1e-24 81.0 Pfam-A 4-200 (200) alignment
Range on Protein: 152-353
Range on HMM: 4-200/200.0
AVYGDLGVENGRS---LGHIQKMAQKGQLDMVLHVGDFAYNMDESNGETGDEFfRQIEPVAGYIPYMATVGNHEYYNNFTHYVNRFTMP---NSEHNLFY
.| |||.  .  .   |  ..|.|.... |.||. ||. .  |.|... ..   .. .... .||.... ||||...  . |  . ...   .   | ..
lvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalld.ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangee

SYDVGPvHFVVFSTEFYFYTQWGYHQMENQYNWLINDLKKANSNRHNIPWIITMGHRPMYCSDFDGDDCtkyesvirtGLPLTHGYALEKLFYEYGVDVE
.|.  .  . .. . ....  . |.   . ... ... . |...|......| ..|.|...|.  |||          | .|   .|||||...||||. 
eyenlk.itllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi.........gselfgpdalekllekygvdlv

LWAHEHSY
|..|.| .
lrGHtHkp

subfamily_ACP5_pd Subfamily ACP5 153-354 3.4e-74 240.9 In-house 1-189 (189) alignment
Range on Protein: 153-354
Range on HMM: 1-189/189.0
VYGDLGVENGRSLGHIQKMAQKGQLDMVLHVGDFAYNMDESNGETGDEFFRQIEPVAGYIPYMATVGNHEYYNNFTHYVNRFTMPnsEHNLFYSYDVGPV
|.|||||....|| ...| .....||...||||.||.....|....|||...|||.| ..|||...||||. .||..| .||.||  ..| .||.|.|||
vfgDlgvseaaslatllkeeeaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesdsnfsaykkrfsmp..sknewYsfdygpv

HFVVFSTEFYFYTQwgyhqmENQYNWLINDLKKANsNRHNIPWIITMGHRPMYCSDFDGDDCTKYESVIRTGlpltHGYALEKLFYEYGVDVELWAHEHS
||...||| .|...      ..||.|| .|||.|| ||.. ||||.|||||||||. |.||||| |...|.|    . ..||.|.|.|.||. |..||||
hfislstevdfslg......seqykWLekdLkean.nrkktpwiivmgHrPmYcsnkdeddctkeetlvrkg....lresledllykykvdlalsgHeHs

YE
||
Ye

ACP5 166-313 7.1e-13 40.7 In-house 20-172 (198) alignment
Range on Protein: 166-313
Range on HMM: 20-172/198.0
GHIQKMAQKGQLDMVLHVGDFAYNMDESNGETG---DEFFRQIEPVAGYIPYMATVGNHEYYNNFTHYVNRFTMPNSEHNLFYSY--DV-GPVHFVVFST
 ...|.|.| ..|.|| .||  |.   .. .     ..| .  .  .  .|.. ..|||.|..| .  ..     .... . . |  ..   |  .. ..
kqmgkvaekldidfvlslGDnfyddGvtsvddprfkesfekiytakslqvpWyvvlGNHDyrgnvsaqieyakrskdsrfpslryslskkevvtelftek

EFYFYTQWGYHQMENQYNWLINDLKKANSNRHNiPWIITMGHRPMYCSDFDGDD
.   . |.. .. |.. ......|.||...  .  |.| .|| |.|     || 
kdeksdqrevaerekyaeeqlkwlekalaksta.dwkiVvGHhpvySigehgdt

Metallophos_C Iron/zinc purple acid phosphatase-like protein C 377-440 3.1e-22 70.0 Pfam-A 2-62 (62) alignment
Range on Protein: 377-440
Range on HMM: 2-62/62.0
APVHIITGSAGCRENTdvFVEHPPPWSAVRSTDYGFGVMRVYNSTHLNFKQINvAQEGKIDDDF
|||||..|.||.....  | . .|.|||.|..|||.. ..|.|.|||...... ...|.. |.|
ApvhIvvGaAGnglsk..fskpqpewsafresdyGysrltvvNrthLhwefvr.sddgqvlDsf