Synonym: CELE_F18E2.11, F18E2.11
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
PhoD | PhoD-like phosphatase | 103-201 | 2.6e-12 | 37.4 | Pfam-A | 58-159 (453) | alignment | ||
Range on Protein: 103-201
Range on HMM: 58-159/453.0
SVWRYIHRVNLTGLVPGTRYFYHVGSD--HGWSPIFFFTALKEREDGGFIYAVYGDLGVENGRsLGHIQKMAQKGQLDMVLHVGDFAYNMDE--SNGETG
| . |. .|..||| ||..|||.. .. . ||. .. |.|.. . ||... .|.| ...|.| .||.|||.||. |. | . |.
serdytvkvevtgLepgqeyfYrfraeegesespvGrtrTlpeaaveslrlavvSCsnyeqGy.fnayrelaekedlDfvlhlGDyiYeygegtykneer
DEF
.|
eek
|
|||||||||
PAPL | 152-353 | 9.2e-67 | 216.9 | In-house | 1-194 (194) | alignment | |||
Range on Protein: 152-353
Range on HMM: 1-194/194.0
AVYGDLGVENGRSLGHIQKMAQKGQLDMVLHVGDFAYNMDESNGETGDEFFRQIEPVAGYIPYMATVGNHEYYNNFTHYVNRFTMPNSEHNLFYSYDVGP
||.|||| .| .|| .||..|||..|..|||||.||..||.|...||||.|||||.| ..|||...||||. .||..|..||.||.||.. ..|.. |.
avfGDlGqtnasslkrlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeeynfsnykarfsmpgseegesnssesgs
VHFVVFSTEFYFYTQWGYHQ-MENQYNWLINDLKKANSNRHNIPWIITMGHRPMYCSDFDGDDCTKYESvirtglpltHGYALEKLFYEYGVDVELWAHE
.. . .. .|.... ... |.. .. .....|. || . ||||.|||||||||. | |||.. .. . .|||.|.|.||||..|..||
nsysfetesvhfivlsseedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdkddckekak.........mlaaledllykygVDlvlaGHe
HSY
|||
HsY
|
|||||||||
Metallophos | Calcineurin-like phosphoesterase | 152-353 | 1e-24 | 81.0 | Pfam-A | 4-200 (200) | alignment | ||
Range on Protein: 152-353
Range on HMM: 4-200/200.0
AVYGDLGVENGRS---LGHIQKMAQKGQLDMVLHVGDFAYNMDESNGETGDEFfRQIEPVAGYIPYMATVGNHEYYNNFTHYVNRFTMP---NSEHNLFY
.| |||. . . | ..|.|.... |.||. ||. . |.|... .. .. .... .||.... ||||... . | . ... . | ..
lvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalld.ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangee
SYDVGPvHFVVFSTEFYFYTQWGYHQMENQYNWLINDLKKANSNRHNIPWIITMGHRPMYCSDFDGDDCtkyesvirtGLPLTHGYALEKLFYEYGVDVE
.|. . . .. . .... . |. . ... ... . |...|......| ..|.|...|. ||| | .| .|||||...||||.
eyenlk.itllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi.........gselfgpdalekllekygvdlv
LWAHEHSY
|..|.| .
lrGHtHkp
|
|||||||||
subfamily_ACP5_pd | Subfamily ACP5 | 153-354 | 3.4e-74 | 240.9 | In-house | 1-189 (189) | alignment | ||
Range on Protein: 153-354
Range on HMM: 1-189/189.0
VYGDLGVENGRSLGHIQKMAQKGQLDMVLHVGDFAYNMDESNGETGDEFFRQIEPVAGYIPYMATVGNHEYYNNFTHYVNRFTMPnsEHNLFYSYDVGPV
|.|||||....|| ...| .....||...||||.||.....|....|||...|||.| ..|||...||||. .||..| .||.|| ..| .||.|.|||
vfgDlgvseaaslatllkeeeaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesdsnfsaykkrfsmp..sknewYsfdygpv
HFVVFSTEFYFYTQwgyhqmENQYNWLINDLKKANsNRHNIPWIITMGHRPMYCSDFDGDDCTKYESVIRTGlpltHGYALEKLFYEYGVDVELWAHEHS
||...||| .|... ..||.|| .|||.|| ||.. ||||.|||||||||. |.||||| |...|.| . ..||.|.|.|.||. |..||||
hfislstevdfslg......seqykWLekdLkean.nrkktpwiivmgHrPmYcsnkdeddctkeetlvrkg....lresledllykykvdlalsgHeHs
YE
||
Ye
|
|||||||||
ACP5 | 166-313 | 7.1e-13 | 40.7 | In-house | 20-172 (198) | alignment | |||
Range on Protein: 166-313
Range on HMM: 20-172/198.0
GHIQKMAQKGQLDMVLHVGDFAYNMDESNGETG---DEFFRQIEPVAGYIPYMATVGNHEYYNNFTHYVNRFTMPNSEHNLFYSY--DV-GPVHFVVFST
...|.|.| ..|.|| .|| |. .. . ..| . . . .|.. ..|||.|..| . .. .... . . | .. | .. ..
kqmgkvaekldidfvlslGDnfyddGvtsvddprfkesfekiytakslqvpWyvvlGNHDyrgnvsaqieyakrskdsrfpslryslskkevvtelftek
EFYFYTQWGYHQMENQYNWLINDLKKANSNRHNiPWIITMGHRPMYCSDFDGDD
. . |.. .. |.. ......|.||... . |.| .|| |.| ||
kdeksdqrevaerekyaeeqlkwlekalaksta.dwkiVvGHhpvySigehgdt
|
|||||||||
Metallophos_C | Iron/zinc purple acid phosphatase-like protein C | 377-440 | 3.1e-22 | 70.0 | Pfam-A | 2-62 (62) | alignment | ||
Range on Protein: 377-440
Range on HMM: 2-62/62.0
APVHIITGSAGCRENTdvFVEHPPPWSAVRSTDYGFGVMRVYNSTHLNFKQINvAQEGKIDDDF
|||||..|.||..... | . .|.|||.|..|||.. ..|.|.|||...... ...|.. |.|
ApvhIvvGaAGnglsk..fskpqpewsafresdyGysrltvvNrthLhwefvr.sddgqvlDsf
|