Gene H25K10.1 in Caenorhabditis elegans

Synonym: CELE_H25K10.1, CELE_H25K10.1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP110_AA protein Get Run
CeleP110_AA_123-322 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PhoD PhoD-like phosphatase 78-165 9.1e-09 25.8 Pfam-A 59-150 (453) alignment 
Range on Protein: 78-165
Range on HMM: 59-150/453.0
QMRYTHRATMQNLVQGKVYYYQVGS--SQAMSSIFNFRQPDQF--QPLRAAIFGDLSVDIGQETIDYLTTKRDQLDVIIHIGDLAYNLHDQN
.. || ......| .|. |.|.. .  ... | . ..|   .   . || |....  .  |  ..   ......||...|.||  |. ....
erdytvkvevtgLepgqeyfYrfraeegesespvGrtrTlpeaaveslrlavvSCsnyeqGyfnayrelaekedlDfvlhlGDyiYeygegt
Metallophos Calcineurin-like phosphoesterase 122-320 2.7e-20 66.5 Pfam-A 2-200 (200) alignment 
Range on Protein: 122-320
Range on HMM: 2-200/200.0
RAAIFGDLSVDIGQE----TIDYLTTKRDQLDVIIHIGDLAYNLHDQNGTTGDEYmNVIEPFAAYVPYMVFAGNHESNSIFNHIIHRFTMPKNGVYNDNL
| ...|||  .  .      | .   .. . |.... ||| .   . ..| .. . .  .......|...  ||||| ..     .. ...|  ....| 
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalld.ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglang

FWSFD------FGNAHFIGLNSEYYPEKMSKEAQAQYKWLREDLEQNSRNWVIVMLHRPWYCSNETPEGCndgwdtlprQGLGKLFPGLEDLLNEYTVDM
.....           ... .|  ||..  .....| ... . .. .  ...|.. |.|...| .. .           ..     . ||.||..| ||.
eeeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi.........gselfgpdalekllekygvdl

VLYGHRHTY
||.|| | .
vlrGHtHkp
Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 122-350 3.5e-10 32.1 Pfam-A 2-133 (156) alignment 
Range on Protein: 122-350
Range on HMM: 2-133/156.0
RAAIFGDLSVDIGQ--ETIDYLttkrDQLDVIIHIGDLAYnlHdqngttgdeyMNVIEPFAAYvPYMVFAGNHESNSIFNHIIHRFtmpkngvyndnlfw
..||..||   . .  . ....     . |.|.| |||    .          . |.| .... |  .  |||. . . ... ...              
kiaiiSDlHgnldaleavledi....kevdlilhaGDlve..p..........eevvelledi.pvlavrGnhDeaelpkelavel..............

sfdfgnahfiglnseyypekmskeaqaqykwLREDLEQNSRNWVIVMLHRpwycsneTPEGCNDGWDTlprqglgklfpgLEDLLNEYTVDMVLYGHRHT
                               | . .. . ... ....|.       || ..... .             |. ||.|. .|.|..|| | 
...............................llaaaaleiegdrvllvhg.......tplsvqsseee............laellkeagadlvflGHtHk

YERmwpiynknpyksenpghiKNAPAPVYIL
..                   .   . ... 
pkv..................ekrggtlvvn
PAPL 124-320 9.9e-52 167.9 In-house 1-194 (194) alignment 
Range on Protein: 124-320
Range on HMM: 1-194/194.0
AIFGDLSVDIGQE-TIDYLTTKRDQLDVIIHIGDLAYNLHDQNGTTGDEYMNVIEPFAAYVPYMVFAGNHESNSIFNHIIHRFTMPKNGVYNDNL-----
|.||||  .  .. .  . .|.....|.|.|.|||||....||...|||.|. |||.||.||||| .||||... |..  .||.||..   . |      
avfGDlGqtnasslkrlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeeynfsnykarfsmpgseegesnssesgs

-FWSFDFGNAHFIGLNSeyypEKMSKEAQAQYKWLREDLEQNSR---NWVIVMLHRPWYCSNETPEGCNDGWdtlprqglgKLFPGLEDLLNEYTVDMVL
  .||... .||| |.|    |.  || . ||.|| |||... |    |.|||.|||.||||.. . |...          | . .||||| .| ||.||
nsysfetesvhfivlss....eedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdkddckeka.........kmlaaledllykygVDlvl

YGHRHTY
 || |.|
aGHeHsY
subfamily_ACP5_pd Subfamily ACP5 125-321 4.5e-65 211.1 In-house 1-189 (189) alignment 
Range on Protein: 125-321
Range on HMM: 1-189/189.0
IFGDLSVDIGQETIDYLTT-KRDQLDVIIHIGDLAYNLHDQNGTTGDEYMNVIEPFAAYVPYMVFAGNHESNSIFNHIIHRFTMPkngvyNDNLFWSFDF
.||||.|. .... ..|.. ....||.|||.|||||.|...|....||.||.|||.|..|||||..|||||.| |... .||.||     ..| ..|||.
vfgDlgvseaaslatllkeeeaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesdsnfsaykkrfsmp.....sknewYsfdy

GNAHFIGLNSEYYPEKMskeaQAQYKWLREDL----EQNSRNWVIVMLHRPWYCSNETPEGCnDGWDTLPRQGlgkLFPGLEDLLNEYTVDMVLYGHRHT
|..|||.|..|..  .     . |||||..||    ......|.||| |||.||||.. . | .  .|| |.|   |...|||||..|.||..|.||.|.
gpvhfislstevdfslg....seqykWLekdLkeannrkktpwiivmgHrPmYcsnkdeddc.tkeetlvrkg...lresledllykykvdlalsgHeHs

YE
||
Ye
ACP5 143-318 2.8e-10 32.2 In-house 26-197 (198) alignment 
Range on Protein: 143-318
Range on HMM: 26-197/198.0
TKRDQLDVIIHIGDLAYNLHDQNGTTG---DEYMNVIEPFAAYVPYMVFAGNHESNSIFNHIIHRFTMPKNGV-Y------NDNLFWSFDFGNAHFIGLN
... ..|... .||  |.   .. .     ... .. .  .  ||..| .|||. .   .  |.     |.   .      ... .    | . .    .
aekldidfvlslGDnfyddGvtsvddprfkesfekiytakslqvpWyvvlGNHDyrgnvsaqieyakrskdsrfpslryslskkevvtelftekkdeksd

SEYyPEKMSKEAQAQYKWLREDLEQNSRNWVIVMLHRPWYCSNETPEGcndgwDTLPRQglgklfpgLEDLLNEYTVDMVLYGHRH
...  .. .|.|. | |||.. |.... .|.||. | | |   |  .      ..| ..        |. ||..| ||. | || |
qre.vaerekyaeeqlkwlekalakstadwkiVvGHhpvySigehgdt.....kelver........llpllkkykvdaYlnGHdH
subfamily_PAPL_pd Subfamily PAPL 149-319 7e-07 20.6 In-house 36-211 (212) alignment 
Range on Protein: 149-319
Range on HMM: 36-211/212.0
DVIIHIGDLAYN--LHDQN-GTTGDEYMNVIEPFAAYVPYMVFAGNHESNSI------FNHIIHRFTMPKNgVYNDNLFWSFDFGNAHFI-------GLN
......||  |.  ..| .     ... .| .  .  ||..|.||||. .        . .. .|...|.   |. .. ..    . ...         .
qfvlalGDnfYekGvkdvddarfketfedvftaeslqvpwyvvagnHDykGnvsaqiaYsklskrWkfpsl.yytksfkipdsnatvqlvlidtvllcgk

SEY-YP--EKMSKEAQAQYKWLREDLEQNSRNWVIVMLHRPWYCSNEtpEGcndgwdtlPRQglgKLFPGLEDLLNEYTVDMVLYGHRHT
|.   .   . .. |..|..||.|.|.... ...||  | | .   |  .|        | .    |   |. ||..| |.  | || |.
sddlklegpvdvslaeeqwawleeeLkaseadylivaGhypvwsvae..hG........ptk...iLvkrLkPlLekynvtaylsGhDhn
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 345-409 7.5e-18 56.0 Pfam-A 2-62 (62) alignment 
Range on Protein: 345-409
Range on HMM: 2-62/62.0
APVYILTGSAGChsHEDPSDHIMQDFSVKALGEYGYTYLTVHNSTHLFTDFVDTFSGNItsLDSF
|||.|..|.||.  .... .. ....|.    .|||. |||.|.|||  .|| . .|..  ||||
ApvhIvvGaAGn..glskfskpqpewsafresdyGysrltvvNrthLhwefvrsddgqv..lDsf