Gene pho-6 in Caenorhabditis elegans

Synonym: CELE_F52E1.8, pho-6

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily ACP2
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP146_AA protein Get Run
CeleP146_AA_14-360 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0048946 Phosphoglycerate mutase-like 15-360 1.3e-69 228.2 In-house 37-412 (447) alignment 
Range on Protein: 15-360
Range on HMM: 37-412/447.0
STANLIIMQAIWRHGDRAPGDlPY--------------------------PKDKY---NETFWPRGWDQLTNKGIWQAVELGIWLRQRYgATVLPifDKD
. ..|. .|...|||.|.| . .|                          . .||   ||..|| |..|||..|. |..||| .||.||  . ||  ...
egcelkqvqvlfRHGaRtPtk.kylkgleplldllknanvlelggdlsflndwkyqlkneplwpcglgqLTplGreqlyelGkrlrkrY.lgllp..nps

KVFILSSDSERAIETAQGVSAGLFPPVddrvwessYLRYWQPTPIQTAYGTIDALLRPtkvKCPNYDlanEQEEAPIATQINNEYGQMFNWLQNITGMES
.... |||..|....|| . ||||||         .   .|| ||.|. .. | ||.|    ||...   |.    .|  ... . . ...|....|.  
eiyvrssdvdRtlqSaqaflaGlfppe........pplgyqpipihtvpssndnlllp...sCpafk...ellkkelaeelkellkellerlkkllggln

IDFWNINDLYDIQRE-LD-HNMpqPQWLnQVFNGtTIMDHIRELKRITRNQEFN-SPTKAKFRGGMLVNQFLQNMEDLKANKTtkNAMMYSSHDGTLSAL
.......||||.    .  |..  . .  ..|.    .. ...|  .   .|.. ..  |. .|| |.|..|...||  ....    ..|..||.|. ||
ltlsdvydlydlllyetaihgl..splc.slftp.eelevleyladlefyyeygygdelarlaggpllneilarledaisgds..klylyfaHdttiaal

LYALNVSNDQLV------------------PYTATVLFELYDDNT---------VQLFYKNTtstayPMTIPGCQQ----ICPYSQFLQLLENVrVRsld
| ||....|.|                   || ... ||||....         |...| ..     |...|||.     .||...|..||... .    
lsaLglfddelplpadnlpfnrlfrsseivPyasnlvfElyecpsslpsdgeyyVrvlynge.....plplpgCgsgpgglCplddFkellkkf.lp...

ALYSLCGTY
  ..|||  
dweklCglt
0047369 Phosphoglycerate mutase-like 15-350 2.2e-69 227.7 In-house 40-432 (438) alignment 
Range on Protein: 15-350
Range on HMM: 40-432/438.0
STANLIIMQAIWRHGDRAP----------------GDLPYPKDKYNETF---WPRGWDQLTNKGIWQAVELGIWLRQRYgatvlPIFDKDKV-FILSSDS
. ..|. .|...|||.|.|                   .||.....      .| |..|||..|. ||.||| .||.||     . .. ..| .. |||.
egcelkqvqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrY.....glLnpedvlyvrssdv

ERAIETAQGVSAGLFPPVDDRVWESsylRYWQPTPIQTAYGTIDALLRP-TKVKCPNYDLANEQEEA-PIATQI-NNEYGQMFNWLQNITGMESIDFWNI
.|....|| . ||||||  . ..      .||| ||.|  .. | ||..     ||..| . ..  | .   .. .... .... | ......  |....
dRtlqSAqaflaGlfppegtgelap...ilwqpipihtipesddfllnllpsdscpafdellkeflasdeflelllkdilkrlkkllpglnltpsdvldl

NDL--YDIQRELDHNMPQPQWLNQVFNGttIMDHIRELKRITRNQEF-NSPTKAKFRGGMLVNQFLQNMEDLKANKT----------------TKNAMMY
.||  ||..   ....|.. ... ..    ... .. |  .   ... ...  || .|| |.|..|...||  ..|.                .   ..|
ydlcaydtlangyaglplspfcslftpe..elevleyladlefyylygygnelaklaggpllneilarledaingkstnlnltldsngvtfPldlklyly

SSHDGTLSALLYALNVSNDQLV---------------------PYTATVLFELYDDN-----TVQLFYknttsTAYPMTIPGCQQ----ICPYSQFLQLL
..||.|. ||| ||....|..                      || ... ||||...      |...|       .....|||..    .||...|..|.
faHdttiaallsaLglfddtwplpglpldkialnrlfrsseivPyasnlvfElyecpsdgeyyVrvly.....ngkvlplpgcgsgpgglCplddFkelv

ENVRVRSL
..... . 
kkllpgdf
subfamily_ACP2_pd Subfamily ACP2 16-359 6.2e-95 310.8 In-house 6-358 (361) alignment 
Range on Protein: 16-359
Range on HMM: 6-358/361.0
TANLIIMQAIWRHGDRAPGDlPYPKDKYNETFWPRGWDQLTNKGIWQAVELGIWLRQRYGA--TVL-PIFDKDKVFILSSDSERAIETAQGVSAGLFPPV
...|...|...|||||.| . .||.|||.|. ||.|. |||..|. |..||| .||.||.   . | . ........ |||..|....|| | |||||| 
erkLkfvqvlfRHGdRsPln.typndkykedewpqglGqLTeeGmqqqyeLGkfLrkrYvedtkfldakynpkqiyvrSsdvnRTlmSaqsvlaglfppe

DDRVWESSYlrYWQPTPIQTAYGTIDALLRpTKVKCPNYD-LANEQEEAPIATQINNEYGQMFNWLQNITG--MESIDFWNINDLYDIQRELDHNMPQPQ
... .....   |||.|..|.... | ||| .| .|| || | .| .| |  .....|. .... |.. ||  ... .|....| . ..|.  .....|.
tgvdypdeq..eWqpvPvhtvseeedlllr.akknCprydellqeakespevkklleenkelleklsestgedidlenfyqlsdtlicerkyanelnlpe

WLNQvfngtTIMDHIRELKRITRNQEFN-----SPTKAKFRGGMLVNQFLQNMEDLKA---NKTTKNAMMYSSHDGTLSALLYALNVSNDQLVPYTATVL
|.|.      ......||..  .. ||.     .....|.|||.|.|..|.||.. .    .|.... ..||.|| || ||| ||.. ... .||.....
wand.....elfekleeladkvkeaefglnnektrelkklrgGpllnellenmkeklkceekkkklklflYSaHDttlaalLeaLgifekkappyasaii

FELYD----DNTVQLFYKNTTSTAYP-MTIPGC--QQICPYSQFLQLLENVRVRSldaLYSLCGT
.|||     ...|...|.|.||.  | .|.|||  .. || |.| ..........   . .|| .
vElyeeddgkplvkvlyrnetskdppeltlpgCkgeedCplskfkkivkpfipdd...vdelCea
0049059 Phosphoglycerate mutase-like 16-348 8.7e-69 225.5 In-house 40-428 (435) alignment 
Range on Protein: 16-348
Range on HMM: 40-428/435.0
TANLIIMQAIWRHGDRAPGD----------------LPYPKDK---YNETFWPRGWDQLTNKGIWQAVELGIWLRQRYgaTVLpiFDKDKVFILSSDSER
 ..|. .|...|||.|.| .                |.||...   .|....| |...||..|. ||.||| .||.||    |  ...|.|.. |||..|
gcelkqvqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrY..gfL..ynpdevyvrssdvdR

AIETAQGVSAGLFPPVDDRVWESSYLRYWQPTPIQTAYGTIDALlrpTKVKCPNYDLANEQEEA-PIATQI-NNEYGQMFNWLQNITGMESIDFWNINDL
....|| . ||||||  ....  . |  .||.||.|   ..| |   .   ||..| . ..  | .   .. .... .... | ...|    |.....||
tlqSaqaflaGlfppeilgsqllnplnvyqpvpietvdsdndtl...pydscpafdellkellasdeflelflerilkllqellpglgltpsdvldlydl

--YDIQ-RELDHNMPQPqWLNqVFNGtTIMDHIRELKRITRNQEFN-SPTKAKFRGGMLVNQFLQNMEDLKANKT----------------TKNAMMYSS
  ||.. ..  |..| | . . .|.   ... ...|  .   .... ..  || .|| |.|..|...||  ....                .   ..|..
ckydtlllgyahglplp.fcs.lfte.eelevleyladlefyylygygdeiaklaggpllneilarledaingdstnlnltldsnpatfpldlklylyfa

HDGTLSALLYALNVSNDQLV---------------------PYTATVLFELYDDNT-----VQLFYKNttstaYPMTIPGCQQ----ICPYSQFLQLLEN
||.|. .|| ||.. .|||                      ||.... ||||....     |...| .     .....|||.     .||...|..|...
HdttiapllsaLglfddqlplpadntpfpeldrlfrtseivPyasnlvfElyecpdgneyyVrvlyng.....kvlplpgcgsgpgglCplddFkelvkk

VRVR
.. .
flpg
0048439 Phosphoglycerate mutase-like 17-345 1e-64 212.3 In-house 7-389 (391) alignment 
Range on Protein: 17-345
Range on HMM: 7-389/391.0
ANLIIMQAIWRHGDRAPG-DLPYPKDKYNETFW---PRGWDQLTNKGIWQAVELGIWLRQRY--GATVLPIF--DKDKVFILSSDSERAIETAQGVSAGL
..|. .|...|||.|.|  ..|.. |.. . ..   | |...||..|. |..||| .||.||  .  . . .  ....|.. |||..|....|| . |||
celkqvqvlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqaflaGl

FPPVDDRVWESSYLRYWQPTPIQTAYGT---IDALLRPTKVKCPNYDLANEQEEAPIATQ--------INNEYGQMFNWLQNITGMES------IDFWNI
||| .. |.   ... ..|.   ....|   .. ||... ...... ...|. |.  . .        ..... ..|......| .         .....
fpplgltvilvivvesedpllnplpintcplledlllldalsalprfylseilerlaevlnrvlglnltaedvlslfdlcaketaalgsllklssplcdl

NDLYD-IQRELDHNMPQPQWLNQVFNGTTIMDHIRELKRITRNQEFNSPTKAKFRGGMLVNQFLQNMedLKANKTTKNAMMYSSHDGTLSALLYALNVSN
..||| .. |  |..| |.||.. .     .. ...|     .  ..|.  || .|| |.|..|...    .....   ..|..||.|. ||| ||.. |
ftlydtllyeyahglplpewltdellspellkqladlvnelyyyltgsgeiaklaggpllneilddl..vangpsdpklylyfaHdttiaallsaLglfn

D------QLVPYTATVLFELYDDNT-----VQLFYKNTTSTAY---------------PMTIPGCQQ----ICPYSQFLQLLENV
|      .|.|| ... ||||....     |...| . | . .               ....|||..    .||...|..|....
dtlplpadlppyasnlvfElyecpsdgeyyVrvlynggtldlprdltlldldefllrlvlplpgcgsgpgglCplddFvelvkkr
0053031 Phosphoglycerate mutase-like 18-350 1.9e-72 237.4 In-house 2-336 (342) alignment 
Range on Protein: 18-350
Range on HMM: 2-336/342.0
NLIIMQAIWRHGDRAPgDLPYPKDKYNETFWPRGWDQLTNKGIWQAVELGIWLRQRYGATVLPIFDKDKVFILSSDSERAIETAQGVSAGLFPPVDDRVW
.|. .....|||.|.|    .|.| .||.|.| |...||..|. ||.||| .||.||.  . .....|.|.. |||..|....|| . |||||| .  ..
eLkqvivlvRHGaRtP.lskgpldplnewfypcgageLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSAqaflaGlfppegtpil

ESsyLRYWQPTPIQTAYGTIDALLRPTKVKCPNYDLA-NEQEEAPIATQINNEYGQMFNWLQNITGMESIDFWN-INDLYDI-QRELDHNMPQPQWLNQV
.   |  ||| ||.|   . ||||.| .  ||..| . .|    .   .....| .....| ...|..  |... ..||||. . || |..| |.|... 
np..llgwqpipihtepessdalllpnydpcpafdkllkealaseevkellerylellqklskglgltlsdlldlvsdlydlllyelahglplppwctlf

FNGTTIMDhiRELKRITRNQEFNSPTKAKFRGGMLVNQFLQNMEDLKANKTTKNAMMYSSHDGTLSALLYALNVSNDQLVPYTATVLFELYDDNT---VQ
.  . .     .|     .. ....  || .|| |.|..|...|.  .....   ..|..||.|. ||| ||.. .||| || ... ||||.|.    |.
tleelkal..yaldllyyyglgpgnelaklaggpllneilarleekisgpldlklylyfahdttiaallsaLglfddqlPpyasnlvfElyedpgeyyVr

LFYKNT-TSTAYPMTIPGCQQICPYSQFLQLLENVRVRSL
..| .  .|. .....|||...||.|.|..|........ 
vlynggtlseplvlplpgcdglcplsefkelvkkllpgdf
0046349 Phosphoglycerate mutase-like 18-360 3.1e-70 230.3 In-house 6-396 (409) alignment 
Range on Protein: 18-360
Range on HMM: 6-396/409.0
NLIIMQAIWRHGDRAP---GDLPYPKDKYNETFWPRGWDQLTNKGIWQAVELGIWLRQRYGAtvLPI------FDKDKVFILSSDSERAIETAQGVSAGL
.|. .|...|||.|.|    ..  . . .| |..|.|..|||..|. ||.||| .||.||    | .      ...|.... |||..|....|| . |||
eLkqvqvlfRHGaRtPtkklsflpnwpginwtngpcgagqLTplGreqayelGkrlrkrYvd..lgLlpsnslynpdeiyvrssdvdRtlqSAqaflaGl

FPPVDDRVW----ESSYLRYWQPTPIQTAYGTI----DALLRPTKVKCPNYDLA--NEQEEAPIATQ-----------INNEYGQMFNWLQNIT-----G
||| .. ..     . .  ..|| ||.|..  .    |. | |..  ||..|    . .. ..   .           ...|. .....| ...     |
fpplggeivpllrqdlldppfqpipidtvpiseddalddtllppdslcpaldkllkenlkslsevleflvdealldlelldetkdllkklaerlnselpg

MESIDFWNIND-LYD-IQRELDHNMPQPQWLNQVFNgtTIMDHIRELKRITRNQEFNSPTKAKFRGGMLVNQFLQNMEDLKANKT------TKNAMMYSS
.. .|.... . ||| .. |. |..| |.| . ..    .......| ..  . ...|.  || .|| |.|..|...||  ..|.      .   ..|..
lnltdpldvasllydtllyetahglplppwcdlftp..eelkvlayladleyyylygsgelaklaggpllneilarledaisgknpvtfpldlklylyfa

HDGTLSALLYALNVSN-----DQLVPYTATVLFELYDD-----NTVQLFYKNTtstayPMTIPGCQQICPYSQFLQLLENVRVR----SLDALYSLCGTY
||.|. ||| ||....      ...|| ... ||||..       |...| .      |...|||...||.|.|..||......    . | | .|.. .
HdttiaallsaLglfdrlfrssdippyasnlvfElyecpsdgeyyVrvlyngg.....plplpgcgegcplsefkellkkrlpgcgltdfdklCpledfl
0049226 Phosphoglycerate mutase-like 19-350 6.1e-73 238.9 In-house 3-336 (342) alignment 
Range on Protein: 19-350
Range on HMM: 3-336/342.0
LIIMQAIWRHGDRAPGDlPYPKDKYNETFWPRGWDQLTNKGIWQAVELGIWLRQRYGATVLPIFDKDKVFILSSDSERAIETAQGVSAGLFPPVDDRVWE
|. .|...|||||.| .  .|.| .||.||. |...||..|. ||.||| .||.||.  . .....|.|.. |||..|....|| . ||||||    ...
LkqvqvliRHGdRtPla.kgpldflnewfwgcglgeLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSaqaflaGlfppeltpilv

SSYLryWQPTPIQTAYGTIDALLRPTKVKCPNYD-LANEQEEAPIATQINNEYGQMFNWLQNITGMESIDFWNIND-LYD-IQRELDHNMPQPQWLNQvF
. .   ||| ||.|   . |.||.. .  |||.| | .|    . . ....|. .... | ...|.. ...... | ||| .. || |..| |.|... |
plld..wqpipiitepesndtllllpydscpnfdkllkellkseevqlfleeildllkklskllglnlstlsdvadtlydlllyelahglplppwcsl.f

NGTTIMDHiRELKRITRNQEFNSPTKAKFRGGMLVNQFLQNMEDLKANKTTKNAMMYSSHDGTLSALLYALNVSNDQLVPYTATVLFELYDDNT---VQL
.   ..    .|     .  ....  |. .|| |.|..|...|.   ....   ..|..||.|. ||| ||.. .||| || ... ||||...    |..
tleelkal.yaldllyyygigygeeiarlaggpllneilarleeaiegpsdlklylyfahdttiaallsalglfddqlPpyasnlvfElyecdgeyyVrv

FYKNTT-STAYPMTIPGCQQICPYSQFLQLLENVRVRSL
.| . . |. .....|||. .||...|..|...... . 
lynggvlslpvtlplpgcdglcpldefkelvkkflpgdf
His_Phos_2 Histidine phosphatase superfamily (branch 2) 19-314 4.5e-42 137.1 Pfam-A 2-346 (347) alignment 
Range on Protein: 19-314
Range on HMM: 2-346/347.0
LIIMQAIWRHGDRAP------------------------GDLPYPKDK-YNETFWPRGWDQLTNKGIWQAVELGIWLRQRYGATVLPIFDKDKVFILSSD
|  .....|||||.|                        ... .|..| ...  .. .|..||..|  ||.||| .|||||.  . .......|.| ||.
LkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYpgllrdhltyedvkirsss

SERAIETAQGVSAGLFPPVDD-RVWESSYLRYWQPTPIQTAYG---TIDALLRPTKVKCPNYDL---ANEQEEAPIATQINNEYGQMFN-WLQNI-TG--
..| ...|| . |||..|  .  . . . |. ... ...|      . ..|||. . .||...    ..|..  .   . .... . ..  |... ||  
erRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalctged

-MESIDFWNINDLYDIQRELDHNMPQPQWLNQVfngTTIMDHIRELKRITRNQE--FNSPTKAKFRGGMLVNQFLQNMEDLKANKT---TKNAMMYSSHD
 ..  . |.  .   .. |  .... |.. ...    . . |.|.|.. ..       ..  .. .|. |.|. |.....   ...   ..   .|..||
nllfkerweklfreffeeekfdiskipelydtm...kydalhnrqledleelyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfthD

GTLSALLYALNVSN------DQLVPYTATVLFELYD-DNT---VQLFY
 .. .|| ||....       . .|| . . ||||  ...   |.|..
shiytllnaLgleekiareaspelpyasqivfelyedsekkfyvrllf
His_Phos_2 Histidine phosphatase superfamily (branch 2) 19-314 4.5e-42 137.1 In-house 2-346 (347) alignment 
Range on Protein: 19-314
Range on HMM: 2-346/347.0
LIIMQAIWRHGDRAP------------------------GDLPYPKDK-YNETFWPRGWDQLTNKGIWQAVELGIWLRQRYGATVLPIFDKDKVFILSSD
|  .....|||||.|                        ... .|..| ...  .. .|..||..|  ||.||| .|||||.  . .......|.| ||.
LkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYpgllrdhltyedvkirsss

SERAIETAQGVSAGLFPPVDD-RVWESSYLRYWQPTPIQTAYG---TIDALLRPTKVKCPNYDL---ANEQEEAPIATQINNEYGQMFN-WLQNI-TG--
..| ...|| . |||..|  .  . . . |. ... ...|      . ..|||. . .||...    ..|..  .   . .... . ..  |... ||  
erRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalctged

-MESIDFWNINDLYDIQRELDHNMPQPQWLNQVfngTTIMDHIRELKRITRNQE--FNSPTKAKFRGGMLVNQFLQNMEDLKANKT---TKNAMMYSSHD
 ..  . |.  .   .. |  .... |.. ...    . . |.|.|.. ..       ..  .. .|. |.|. |.....   ...   ..   .|..||
nllfkerweklfreffeeekfdiskipelydtm...kydalhnrqledleelyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfthD

GTLSALLYALNVSN------DQLVPYTATVLFELYD-DNT---VQLFY
 .. .|| ||....       . .|| . . ||||  ...   |.|..
shiytllnaLgleekiareaspelpyasqivfelyedsekkfyvrllf
His_Phos_1 Histidine phosphatase superfamily (branch 1) 25-128 1.1e-10 34.7 Pfam-A 4-91 (158) alignment 
Range on Protein: 25-128
Range on HMM: 4-91/158.0
IWRHGDRApgdlpypkdkYNETFWPRGWDQ--LTNKGIWQAVELGIWLRQrygatvlpiFDKDKVFILSSDSERAIETAQGVSAGLFPP--VDDRVWESS
. ||| .           .|.    .|| .  ||.||..|| ||| .|..          |     . .|.. |||.||......|  |   ..|. | .
lvRHGese..........wnkegrlqgwsdvpLtekGreqarelgkkLkr.........adlpidavytSplkRaiqTaeilleeldipiikeprLrerd

YlRYWQPT
.   |.  
f.gewegl
His_Phos_1 Histidine phosphatase superfamily (branch 1) 25-128 1.1e-10 34.7 In-house 4-91 (158) alignment 
Range on Protein: 25-128
Range on HMM: 4-91/158.0
IWRHGDRApgdlpypkdkYNETFWPRGWDQ--LTNKGIWQAVELGIWLRQrygatvlpiFDKDKVFILSSDSERAIETAQGVSAGLFPP--VDDRVWESS
. ||| .           .|.    .|| .  ||.||..|| ||| .|..          |     . .|.. |||.||......|  |   ..|. | .
lvRHGese..........wnkegrlqgwsdvpLtekGreqarelgkkLkr.........adlpidavytSplkRaiqTaeilleeldipiikeprLrerd

YlRYWQPT
.   |.  
f.gewegl
0051064 Phosphoglycerate mutase-like 26-319 1.6e-10 33.9 In-house 9-234 (241) alignment 
Range on Protein: 26-319
Range on HMM: 9-234/241.0
WRHGDRAPGDLPY--PkdkynetfwpRGWDQLTNKGIWQAVELGIWLRQRygatvLPIFDkdkvFILSSDSERAIETAQGVSAGLFPPVddrvwessylr
.||| .     .              .   .|| .|..|| .|| .|...     .. ||     ..||.  |||.||. . ..|  |            
vRHGesewnaegrlqg..........wtDvpLtelGreqaralgerladl.....gikfd....avysSpllRaiqTaeiiaealglpl...........

ywqptpiqtaygtidallrptkvkcpnydlaneqeeapiatqinneygqmfnwlqnitgmesIDFWNINDLYDIQRELDHNMPQPQWLnQVFNGTTIMDH
                                                              ...   ..|..|    ..... ...  . |..   . .
..............................................................lpvvvdprlrEidfgalegltleeia.ekfpeelvawl

IRELK------------RITRNQEFNSPTKAKFRGG----MLVNQFLQNMEDLKAN--KTTKNaMMYSSHDGTLSALLYAL-----NVSNDQLVPYTATV
 ..|              .. .  ... ..  . ||    .... .|. .|.| |.  .  ||  .  ||.|.. |||  |     .   .  .|... .
rdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellarllldgkn.vlvVsHggvirallayllglpleellrlnlpngsvt

LFELYDDN-TVQLFYKNTTS
 .|| ||  .|.| . | ||
vleldddgkrvvlvllndts
0048955 Phosphoglycerate mutase-like 26-182 2.2e-10 33.4 In-house 6-72 (240) alignment 
Range on Protein: 26-182
Range on HMM: 6-72/240.0
WRHGDRAPG--DLPYPkdkynetfwpRGWDQLTNKGIWQAVELGIWLRQRygatvLPIFDkdkvFILSSDSERAIETAQGVSAGLfppvddrvwessylr
.||| .     .. .           .   .|| .|..|| .|| .|...      . ||     ..||.  |||.||. . ..|               
vRHGesewnaegrlqg..........wtDvpLtelGreqaralgerLadl.....gikfd....lvysSpllRaiqTaeiiaeal...............

ywqptpiqtaygtidallrptkvkcpnydlaneqeeapiatqinneygqmfnwlqnitG
                                                          |
..........................................................g
0036887 Phosphoglycerate mutase-like 50-130 2e-08 26.7 In-house 23-93 (202) alignment 
Range on Protein: 50-130
Range on HMM: 23-93/202.0
RGWDQLTNKGIWQAVELGIWLRqrygatvlpifDKDKVFILSSDSERAIETAQGVSA--GLFPPVDDRVWESsYLRYWQPTPI
.    || .|..|| .|| .|.           . .   ..||.  |||.||. ...  || . ||.|  |  .. ...  ..
dldvpLtelGreqaralgerla...........glpfdavysSpllRaiqTaeiiaealglpvivdprlrEi.dfgalegltl
0035570 Phosphoglycerate mutase-like 52-121 2.9e-08 26.0 In-house 21-79 (219) alignment 
Range on Protein: 52-121
Range on HMM: 21-79/219.0
WDQLTNKGIWQAVELGIWLRQRYgatvlpifdKDKVFILSSDSERAIETAQGVsaGLFPPVDDRVWESSY
   || .|..|| .|| .|...           .  ...||.  |||.||. .  || . .|.|  | ..
dvpLterGreqaralgealadlg.........ipfdavysSpllRaiqTaeii..glpveidprLrEidf
0039931 Phosphoglycerate mutase-like 52-121 3.4e-08 25.7 In-house 21-79 (219) alignment 
Range on Protein: 52-121
Range on HMM: 21-79/219.0
WDQLTNKGIWQAVELGIWLRQRygatvlpifDKDKVFILSSDSERAIETAQGVsaGLFPPVDDRVWESSY
   || .|..|| .|| .|...         . .   ..||.  |||.||. .  || . .|.|  | ..
dspLterGreqaralgerlkdl.........glpfdavysSpllRaiqTaeii..glpveidprLrEidf
subfamily_ACP6_pd Subfamily ACP6 53-347 6.8e-29 92.7 In-house 76-363 (376) alignment 
Range on Protein: 53-347
Range on HMM: 76-363/376.0
DQLTNKGIWQAVELGIWLRQRYGATV--L-PIFDKDKVFILSSDSERAIETAQGVSAGLFPPVDdrvwessyLRYWQPTPIQTAYGTiDALLRPTKVKCP
 |||. |  |. .||  ||.||   .  | . |  ..|.| | . ||..| |. . |||.  .          .   |  . |  .  .. | | . .||
GqLtkvGmqqvfdLGrkLrkrYvedikfLsqefnpqevyiRstnieRtlesarclvaGLygkii........iqkelpiilytdeed.eevlyPnrqrcp

NYDLANEQEEAPI--ATQINNEYGQMFNWLQnITGMESIDFWNINDlyDIQRELDHNMPQPQWLNQVFNgtTIMDHI-RELKRITRNQEFNSPTKAKFRG
    | .. ..       | ..  |. . |. |.  . .||  . |  .|  .|.||.. |. |..|..   | .|  .||  . ....       |.  
llsrayrsvrksaislpGisedtkqiadvld.iseekkldfvslrD..niaArlaHnlkvppilkdvid..liekhAveelvvlleggdrpekeilklsv

GMLVNQFLQNMEDLKANKTT-KNAMMYSSHDGTLSALLYALNVSNDQLVPYTATVLFELYDDNTVQLFYKnTTSTAYPMTIPGCQ-QICPYSQFLQLLEN
| .... |.|.|. | ...  .. ..|| || ||..|| ||.| .|.  |..| | .|||.|.  . | . .  .   . ..|.. ...|. .| .||. 
GkvlkeilenlekakekeiparklrLysaHDttlmtLLlalgvFDdkWPpfaadvileLyedkageyfvr.vlYqekelrlrgseedlvPlekFkallav

VRV
. .
lvl
subfamily_PXYLP1_pd Subfamily PXYLP1 53-311 2.2e-14 44.5 In-house 104-358 (419) alignment 
Range on Protein: 53-311
Range on HMM: 104-358/419.0
DQLTNKGIWQAVELGIWLRQRYGAT--VL---PIFDKDKVFILSSDSERAIETAqgvSAGLFPPVDDRVWESSYLRYWQPTPIQTAYGTIDALLRPTKVK
 |||.||. | .|.|  ||. |. .  .|     . .|.| . .    |..  |    | |.  ...  ... ..|  .         .  ||||  . |
gqLtqkGvvqhLevGdllrkvYakklklLlkpnelssDevvlettrkrrtlqsa...lallygllpkaklkairvrespsvafClgeCsCPallrkrlek

CPNYDLANEQeeapIATQINNEYGQMFNWLQNITGMESIDFWnindLYDIQRELDHNMPQPQWLnqvfNGTTIMDHIRELKRITRNQEFNSPTKA-----
  .  |           .. . .|.. .  . .|  . |       .  .   | ||.. |       .|.  . |.  |.... .   .|  |.     
eadkqlLlrg....kvldvmksvgetlkgtilqttlngisnp....vdalltvlChnvslPcrr....eGcvepshvdvlhkladelsqrsakksyykls

-KFRGGMLVNQFLQNMEDLKANKTTKNAMMYSSHDGTLSALLYALNVSNDQLVPYTATVLFELYDDNTVQ
 ..|   |... ...|  .   .  .. ..||.|| ||. |. ||..|. ... | . ..||||  .. .
GllraypllrdivsrmlkiieGvdkekfvlysghDvtlrplvaaLglseartiayasrlvfelyrreask
0036777 Phosphoglycerate mutase-like 53-129 1.1e-08 27.5 In-house 27-98 (247) alignment 
Range on Protein: 53-129
Range on HMM: 27-98/247.0
DQLTNKGIWQAVELGIWLRQRygatvLPIFDkdkvFILSSDSERAIETAQGVSAGLF-----PPVDDRVWESSyLRYWQPTP
  || .|..|| .|| .|...        ||    ...||.  |||.||. . ..|      . ||.|  | . . ...  .
vpLtelGreqakalgellkel.....glpfd....avysSpllRAiqTaeiilealglsllpvvvdprLrErd.yGaleglt
0053607 Phosphoglycerate mutase-like 53-123 1.7e-08 26.8 In-house 24-83 (191) alignment 
Range on Protein: 53-123
Range on HMM: 24-83/191.0
DQLTNKGIWQAVELGIWLRQRygatvlpifDKDKVFILSSDSERAIETAQGVsaGLFPPVDDRVWESSYLR
  || .|..||  |. .|...         . .   ..||.  ||..||. .  || . ||.|  | ..  
vpLtelGreqaralaellael.........glkfdavysSpllRarqTaeii..glpvevdprlrEidfgd
0043909 Phosphoglycerate mutase-like 53-119 3.3e-08 25.8 In-house 27-89 (249) alignment 
Range on Protein: 53-119
Range on HMM: 27-89/249.0
DQLTNKGIWQAVELGIWLRQRygatvLPIFDkdkvFILSSDSERAIETAQGVSAGLFPP-----VDDRVWES
  || .|..|| .|| .|...        ||    ...||.  |||.||. . ..| ..     ||.|  | 
spLtelGreqaralgealkel.....gipfd....avysSplkRAiqTaeiileelgldklpvevdprLrEr
0037864 Phosphoglycerate mutase-like 53-131 1.4e-07 23.7 In-house 32-105 (211) alignment 
Range on Protein: 53-131
Range on HMM: 32-105/211.0
DQLTNKGIWQAVELGIWLRQRygatvLPIFDkdkvFILSSDSERAIETAQGVSAG-----LFPPVDDRVWEsSYLRYWQPTPIQ
  || .|..|| .|| .|...        ||     ..||.  |||.||. . ..     | . ||.|  |  .. ...  ...
vpLtelGreqaralgealadl.....glpfd....avysSpllRaiqTaeiilealglpllpvevdprlrE.rdfgalegltle
0050036 Phosphoglycerate mutase-like 53-122 2.1e-06 19.7 In-house 25-78 (171) alignment 
Range on Protein: 53-122
Range on HMM: 25-78/171.0
DQLTNKGIWQAVELGIWLrqrygatvlpifdkDKVFILSSDSERAIETAQGVSagLFPPVDDRVWESSYL
  || .|..||  || .|              .  ...||.  ||..||. .   | . ||.| .| .. 
vpLtelgraqaralgell..............pfdavysSpllRArqTaelil..lpvivdprLrErdfG
0049178 Phosphoglycerate mutase-like 54-121 3e-08 26.2 In-house 29-92 (243) alignment 
Range on Protein: 54-121
Range on HMM: 29-92/243.0
QLTNKGIWQAVELGIWLRQRygatvlpifDKDKVFILSSDSERAIETAQGVSAG-----LFPPVDDRVWESSY
 || .|..|| .|| .|...         . .   ..||.  |||.||. . ..     | . ||.|  | ..
pLtelGreqAralgellael.........glkfdavysSplkRaiqTaeiilealglpllpvvvdprLrErdf
subfamily_HP2-Group1_pd Subfamily HP2-Group1 186-343 1.9e-11 34.9 In-house 243-405 (422) alignment 
Range on Protein: 186-343
Range on HMM: 243-405/422.0
IDFWNINDLYD-IQRELDHNMPQPQWLNQVFNGTTImDHIreLKRITRNQEFNSPT-KAKFRGGMLVNQFLQNMEDLKANKTTKNAMMYSSHDGTLSALL
.|  |..|| | ..    ||.  |. | . .  ... | .  | |      . |   .|.   |.|. .  ... .  . .  .  ..|| ||.||  ||
ldidnledlvdclithqchnaaipdkltedlakrgl.del..lyrsysslkypsvekyarvGiGfllkdiwkevnesltGedlrkfllysGhdttliqll

YALNVSNDQLVPYTATVLFELYDDNTVQL--FYKNTTSTAY---PMTIPGCQ-QICPYSQFLQLLE
 ||||.. .  ||.. .|.||..  |       . .    |    ...| |. . |.| || . |.
salnvdefkwppyasllllellevstapaastpqyavrvlynGklkklpfcdanecsyeqfeayls