Gene scpl-4 in Caenorhabditis elegans

Synonym: CELE_T21C9.12, scpl-4

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily TIM50
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP178_AA protein Get Run
CeleP178_AA_246-374 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
CPDc_SM00577 247-374 1.8e-30 97.9 In-house 2-145 (146) alignment 
Range on Protein: 247-374
Range on HMM: 2-145/146.0
KYTIVIELKNILVHP----------EWTYK-----TGYRFLKRPALDYFLDVIGyPNFEVVIYSSESMMTAAPVVDSFDPKQRIMYK-LFRDCTKYMNGH
|...|..|...|||           |.. .     | ...|||| .|.||. .   .||.||..|.|...| ...|  |||....|. |.|. .....|.
kkvLVlDLdetLvhsanmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaa.klfelvifTsaskkyadtildllDpkrllkyrvlyRqdcrlvkgk

HVKD-LSKLNRDLSKVIYIDFDAKSGQLNPENMLRVPEWKGNMDD
..|| || |..|||||. || . .| ..||||.| ..... ...|
llkddlsllkvdlskvviiDnseestlvnpenalkikpyisalsd
NIF NLI interacting factor-like phosphatase 248-396 3.4e-36 116.5 Pfam-A 1-159 (159) alignment 
Range on Protein: 248-396
Range on HMM: 1-159/159.0
YTIVIELKNILVHPEWTY-----------KTGYRFLKRPALDYFLDVIgYPNFEVVIYSSESMMTAAPVVDSFDP-KQRIMYKLFRDCTKYMNGHHVKDL
.|.|..| ..||| ....           || ... ||| ||.||. .   ..||||....|...|.||.| .|| |. . ..|.|. ... ||..||||
ktLVLDLDetLvhskekkdlkedgkkveektkasvkkRPgldeFLkel.skayevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyvKdL

SKLNRDLSKVIYIDFDAKSGQLNPENMLRVPEWKGN-MDDTSLVDLAELLKTIHlsDAEDVR
|.|.||||.|...| ...| .|.|.|.. .....|.  .||.| .| ..|. ..  ...|||
sllgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpfleale..ksddvr
subfamily_TIM50_pd Subfamily TIM50 249-375 3.6e-62 200.1 In-house 1-126 (126) alignment 
Range on Protein: 249-375
Range on HMM: 1-126/126.0
TIVIELKNILVHPEWTYKTGYRFLKRPALDYFLDVIGyPNFEVVIYSSESMMTAAPVVDSFDPKQRIMYKLFRDCTKYMNGHHVKDLSKLNRDLSKVIYI
|.|.|||..|||||||||||.|| |||..|.||. .. ..||.|...||...||||..|..|||| |||.||||.|||..|.||||||||||||||||..
tlvlelkdvlvhpewtyktGwrfkkrPgvdafleqla.elfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivv

DFDAKSGQLNPENMLRVPEWKGNMDDT
|.|.|| .|.|||.|.. .|.||.||.
dldkksvklqpenalalkkweGnaddk
subfamily_DULLARD_pd Subfamily DULLARD 265-375 1.5e-18 59.0 In-house 42-152 (153) alignment 
Range on Protein: 265-375
Range on HMM: 42-152/153.0
YKTGYRFLKRPALDYFLDVIGYpNFEVVIYSSESMMTAAPVVDSFDPKQRIMY-KLFRDCTKYMNGHHVKDLSKLNRDLSKVIYIDFDAKSGQLNPENML
... ..  ||| .|.||||.    ...||. .   . ||.||| .| .. |.  ...|.     .|...|||| .. |||.|| .|  ... . ||.| .
epvlfyvykrPhvDlfLdvvsk.WydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvlesgkytkdlslvssdlssviilDnspvayrknpdnai

RVPEWKGNMDDT
 .  |  . .||
pikswlsdpsdt
subfamily_SCP_pd Subfamily SCP 271-375 5.7e-21 66.8 In-house 39-142 (142) alignment 
Range on Protein: 271-375
Range on HMM: 39-142/142.0
FLKRPALDYFLDVIGYpNFEVVIYSSESMMTAAPVVDSFDPKQRIMYKLFRDCTKYMNGHHVKDLSKLNRDLSKVIYIDFDAKSGQLNPENMLRVPEWKG
 |||| .| ||. .|   ||||....     | ||.| .| |. . ..|||.   . .| .|||||.| |||.||| .|   .|  . ||| . |  |  
vlkrphvdeflkrvge.lfevvlftaslakyadpvadlldkkkvlrarlfrescvfhkgnyvkdlsrlgrdlkkviivdnspasyifhpenavpveswfd

NMDDT
...||
dkedt
subfamily_CTDSPL2_pd Subfamily CTDSPL2 273-374 1.3e-16 52.9 In-house 40-141 (142) alignment 
Range on Protein: 273-374
Range on HMM: 40-141/142.0
KRPALDYFLDVIGyPNFEVVIYSSESMMTAAPVVDSFDPKQR-IMYKLFRDCTKYMNGHHVKDLSKLNRDLSKVIYIDFDAKSGQLNPENMLRVPEWKGN
.|| |  ||. .    |||.....   . |  ..| .||... | ..|||.   ...| ..|||| | |||.|.| .|  ...  .. || . .  |  .
lrpflreflervs.klfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyikdlsilGrdlektiivdnspqafayqlenGipieswfed

MDD
 .|
end