Gene Y105C5B.3 in Caenorhabditis elegans

Synonym: CELE_Y105C5B.3, CELE_Y105C5B.3

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP204_AA protein Get Run
CeleP204_AA_125-327 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PhoD PhoD-like phosphatase 79-167 5.8e-11 33.0 Pfam-A 58-148 (453) alignment
Range on Protein: 79-167
Range on HMM: 58-148/453.0
KTMRYTHRATMQNLVPGQVYYYQVGS--SQAMSSIFHFRQPdPSQPLRAAIFGDLSIIKGQQS-IDQLIEATKQNQLDVIIHIGDLAYDLHD
... || ......| ||| |.|.. .  ... | . ..|   |.. ...  .. .|  ...|  .  . |......||...|.||  |  ..
serdytvkvevtgLepgqeyfYrfraeegesespvGrtrTl.peaaveslrlavvSCsnyeqGyfnayrelaekedlDfvlhlGDyiYeyge

Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 124-345 6.4e-12 37.7 Pfam-A 2-138 (156) alignment
Range on Protein: 124-345
Range on HMM: 2-138/156.0
RAAIFGDLSIikGQQSIDQLIEATkqNQLDVIIHIGDLAYdlHdengatgddyMNAIEPFAAYvPYMVFAGNHEVDGDFNHIKNRFtmprngvydnnlfw
..||..||    . .......|.   .. |.|.| |||    .          .  .| .... |  .  |||. .   .... ..              
kiaiiSDlHg..nldaleavledi..kevdlilhaGDlve..p..........eevvelledi.pvlavrGnhDeaelpkelavel..............

sftygfvhiiainseyyaeemsneakaqyqwLREDLAQNTKKWTIVMFHRpwycsskKKKGCNDDQDIlsregdkkkfpgLEELLNQYKVDMVLYGHKHT
                               | . .| . ........|.       .. .......             |.|||.....|.|..|| | 
...............................llaaaaleiegdrvllvhg.......tplsvqsseee............laellkeagadlvflGHtHk

YERMWpiynKNPFKSANPGHIK
..       ..     ||| . 
pkvek....rggtlvvnpGsvg

PAPL 126-324 3.1e-52 169.5 In-house 1-194 (194) alignment
Range on Protein: 126-324
Range on HMM: 1-194/194.0
AIFGDLSIIKGQQsIDQLIEATKQNQLDVIIHIGDLAYDLHDENGATGDDYMNAIEPFAAYVPYMVFAGNHEVDGDFNHIKNRFTMPRNGVYDNNLFWSF
|.||||   . .. . .| ..|.....|.|.|.|||||.....|. .||..|. |||.||.||||| .|||| . .|.. |.||.|| .   ..| ..| 
avfGDlGqtnass.lkrlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeeynfsnykarfsmpgseegesnssesg

--TYGFVHIIAINSEYYAEEMSNEAKAQYQWLREDLAQN---TKKWTIVMFHRPWYCSSKKKKGCNDDqdilsregdKKKFPGLEELLNQYKVDMVLYGH
  .| |    .    .  ||  .| . ||.|| ||||..    . | |||.|||.|||.|.|. |...         .|.. .||.|| .|.||.|| ||
snsysfetesvhfivlsseedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdkddckek.........akmlaaledllykygVDlvlaGH

KHTY
.|.|
eHsY

subfamily_ACP5_pd Subfamily ACP5 127-325 4.9e-68 220.8 In-house 1-189 (189) alignment
Range on Protein: 127-325
Range on HMM: 1-189/189.0
IFGDLSIIKgQQSIDQLIEATKQNQLDVIIHIGDLAYDLHDENGATGDDYMNAIEPFAAYVPYMVFAGNHEVDGDFNHIKNRFTMPrngvyDNNLFWSFT
.||||.. . ..|...| . ...|.||.|||.|||||.|...|.|..|..||.|||.|..|||||..||||.| .|...|.||.||     ..| ..|| 
vfgDlgvse.aaslatllkeeeaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesdsnfsaykkrfsmp.....sknewYsfd

YGFVHIIAINSEYYAEEMsneaKAQYQWLREDLA----QNTKKWTIVMFHRPWYCSSKKKKGCnDDQDILSREGdkkKFPGLEELLNQYKVDMVLYGHKH
|| ||.|....|..  .     . ||.||..||.    .....|.||| |||.|||.|... | . .. |.|.|   ....||.||..||||..|.||.|
ygpvhfislstevdfslg....seqykWLekdLkeannrkktpwiivmgHrPmYcsnkdeddc.tkeetlvrkg...lresledllykykvdlalsgHeH

TYE
.||
sYe

Metallophos Calcineurin-like phosphoesterase 127-324 2.7e-19 63.3 Pfam-A 5-200 (200) alignment
Range on Protein: 127-324
Range on HMM: 5-200/200.0
IFGDLSIIKGQQ--SIDQLIEATKQNQLDVIIHIGDLAYDLHDENGATGDDYmNAIEPFAAYVPYMVFAGNHEVDGDFNHIKNRFTMPRNGVYDNNLFWS
..||| .   .      .|... .... |.... ||| .   . ..  .. . .  .......|...  ||||.|.     . . ....  .. .| ...
vigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalld.ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangeee

F-------TYGFVHIIAINSEYYAEEMSNEAKAQYQWLREDLAqNTKKWTIVMFHRPWYCSSKKKKGCnddqdilsrEGDKKKFPGLEELLNQYKVDMVL
.       . . . .. ....|.   .| ... . ..|.. |. .   ..|...|.|...| .              ..     . ||.||..|.||.||
yenlkitllttsgelyglsglypllgdsaqeeqleeflalplr.alvdgkilltHgplsssggsgddi.........gselfgpdalekllekygvdlvl

YGHKHTY
.|| | .
rGHtHkp

ACP5 134-322 1.2e-13 43.2 In-house 13-197 (198) alignment
Range on Protein: 134-322
Range on HMM: 13-197/198.0
IKGQQSIDQLIEATKQNQLDVIIHIGDLAYDLHDENGA---TGDDYMNAIEPFAAYVPYMVFAGNHEVDGDFNH-IKNRFTMPRNGVYDNNLFWSFTYGF
 . ..  .|. ........|... .||  ||   ..       ... .  .  .  ||..| .|||.. |. .  |.   .  .. .. .. ..|..  .
ynqsavakqmgkvaekldidfvlslGDnfyddGvtsvddprfkesfekiytakslqvpWyvvlGNHDyrgnvsaqieyakrskdsrfpslryslskkevv

VHIIAI-----NSEYYAEEMSNEAKAQYQWLREDLAQNTKKWTIVMFHRPWYCSSKKKkgcndDQDILS-RegdkkkfpgLEELLNQYKVDMVLYGHKH
....       ... . .| ...|. | .||.. ||..|..|.||. | | |  ....     |.. |  |         |. ||..||||. | || |
telftekkdeksdqrevaerekyaeeqlkwlekalakstadwkiVvGHhpvySigehg.....dtkelver.........llpllkkykvdaYlnGHdH

subfamily_PAPL_pd Subfamily PAPL 141-323 2.5e-09 28.7 In-house 24-211 (212) alignment
Range on Protein: 141-323
Range on HMM: 24-211/212.0
DQLIEATKQNQLDVIIHIGDLAYD--LHDENGAT-GDDYMNAIEPFAAYVPYMVFAGNHEVDGD------FNHIKNRFTMPRNgVYDNNLFWSFTYGFVH
 .| . ... . ......||  |.  ..|.. |   . . .  .  .  ||..|.||||...|.      . .. .|...|    | ... .. .   |.
kelgkvaeeleaqfvlalGDnfYekGvkdvddarfketfedvftaeslqvpwyvvagnHDykGnvsaqiaYsklskrWkfpsl.yytksfkipdsnatvq

IIAINSEYY----------AEEMSNEAKAQYQWLREDLAQNTKKWTIVMFHRPWYcsSKKKKGCNddqDILSREgdkkkfpgLEELLNQYKVDMVLYGHK
.. |.              . . .. |..|..||.|.|....... ||  | | .  |  ..|     .|| ..        |. ||..|.|.  | || 
lvlidtvllcgksddlklegpvdvslaeeqwawleeeLkaseadylivaGhypvw..svaehGpt...kiLvkr........LkPlLekynvtaylsGhD

HT
|.
hn

Metallophos_C Iron/zinc purple acid phosphatase-like protein C 349-413 5.7e-17 53.2 Pfam-A 2-62 (62) alignment
Range on Protein: 349-413
Range on HMM: 2-62/62.0
APVYILTGGAGChsHEDPSDHIMQDFSVKALGEYGYTYLTVYNSTHISTDYVDTSstTGKFLDPF
|||.|..|.||.  .... .. ....|.    .|||. |||.|.||.. ..| ..  .|. || |
ApvhIvvGaAGn..glskfskpqpewsafresdyGysrltvvNrthLhwefvrsd..dgqvlDsf