Gene DDB_G0270196 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily TIM50
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP058_AA protein Get Run
DdisP058_AA_212-319 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
TLP-20 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) 21-99 4.9e-06 12.7 Pfam-A 91-164 (169) alignment 
Range on Protein: 21-99
Range on HMM: 91-164/169.0
TTQFIKPNQTIFLIGGTKrlfttQ-QQQSPKKEEPKSeQQKKVEDKTEEKEKEKDEEENENEKEKENEDGEGQKKKSKFN
.   .| ...|| |  |.     . ...| ....  . .....||...| ....||... .......|... ..||.|..
kptvlkkgsviFkivytn.....kksansklflsapv.eksssededdeddededeaakiesnsdseesepssaKkqklD
TRAP_alpha Translocon-associated protein (TRAP), alpha subunit 33-96 2.6e-06 14.5 Pfam-A 21-79 (285) alignment 
Range on Protein: 33-96
Range on HMM: 21-79/285.0
LIGGTKRLFTTQQQqSPKKEEpkSEQQKKVEDKTEEKEKEKDEEENENEKEKENEDgeGQKKKS
|.| .|.|....|.   ..||  .|...  ||...|.|.| ||... .|.| |.|.  |. |.|
lvgavkklaasaqd.ltedee..aeddvvdedeedeaeveedekteaeeeedeeea..gevkas
DHHW DHHW protein 44-147 4e-08 19.2 Pfam-A 66-167 (378) alignment 
Range on Protein: 44-147
Range on HMM: 66-167/378.0
QQQQSPKKEEPKSEQQKKVEDKTEEKEKEKDEEENENEKEKENEDGEGQKKKSKFNVPPivTSVTSTFFAGVLVASTFGYLTYNFKKDISEEERYRLNSV
.....|..||.....|..| ....|..... |||..||....... | .....|  .    . .. .   .|.||   .|  |.|.|....|    .|.|
ekddapeeeeetaktqnivseasteestaskeeessneeseaetkveekdedakavade..sksqgeiantvyvagdsayelYsfskenadeyastvNnv

ESKF
..| 
akkl
Tim54 Inner membrane protein import complex subunit Tim54 45-99 9.2e-06 11.7 Pfam-A 202-260 (382) alignment 
Range on Protein: 45-99
Range on HMM: 202-260/382.0
QQQSPKKEEPKSEQQKKVEDKTEEKEKEKDEEENENE---KEKENEDGEGQ-KKKSKFN
....|...| .. ....||......|....|||...|   .....|. | . .|| |. 
elkepepteeeeaaetevekteaaeeeaaeeeekaeeekeekedeeeeekekpkkpkvp
CDC45 CDC45-like protein 47-95 7.4e-06 12.5 Pfam-A 131-181 (622) alignment 
Range on Protein: 47-95
Range on HMM: 131-181/622.0
QSPKKEEPKSEQQKKVEDKTEEKEKEKDEEENENEKEKENEDGEGQKK--K
.. ...| ...............||||.|.....|.....||....|.  .
eeeesdedsdseedeeseessksekeksesdedeeddddeedederkrkrs
NIF NLI interacting factor-like phosphatase 196-341 1.1e-24 79.2 Pfam-A 1-159 (159) alignment 
Range on Protein: 196-341
Range on HMM: 1-159/159.0
YTLVIDIDALteITKTS---------------KYPTLYKRAGLDFFLDHLRKDYEIYLYFNGNipQNKYEQLQFKIDTNGKYFTGLLYPETGIKERNQFS
.|||.|.| .  . ...               .   ..|| ||| ||..|.|.||.... ...  ..  |..  |.|...|.|.  || |    ..... 
ktLVLDLDet..LvhskekkdlkedgkkveektkasvkkRPgldeFLkelskayevviftass..keyaepvldkldpkkklfkkrlyresctlrngkyv

KKIEMLDRDPSKVIFIDAASP---YDHPNVINIGKFKSN-SKDKLLIELLPVLeSFSRKNlDDVR
|....|.|| |.|...|  .     .. |.|.| .|... .||. | .|||.| . ..|. ||||
KdLsllgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpfl.ealeks.ddvr
subfamily_FCP1_pd Subfamily FCP1 208-312 9.9e-06 17.7 In-house 36-141 (146) alignment 
Range on Protein: 208-312
Range on HMM: 36-141/146.0
ITKTSKYPTLYKRAGLDFFLDHLRKDYEIYLYFNGNipQNKYEQLQFKIDTNGKYFT-GLLYPETGIKERNQFSKKIEMLDRDPSKVIFIDAASP--YDH
......  .  .| .|  ||..| | ||...|  |.  ..  ||.   .| ..| |.  .|  .  ... ....|  .....| | |. ||  .     .
lpeekevyyvklRpnlkefleklsklyelhiytmgt..raYaeqiakilDpekklfserilsrdelldassktkklkklfptddsmvviiDDredvWnfa

PNVINIGK
.|.|.. .
enlikvkp
CPDc_SM00577 213-319 4.2e-11 35.0 In-house 34-145 (146) alignment 
Range on Protein: 213-319
Range on HMM: 34-145/146.0
KYP---TLYKRAGLDFFLDHLRKDYEIYLYFNGNIPQNKyeQLQFKIDTNGKYFTGLLYPETGIKERNQFSKK-IEMLDRDPSKVIFIDAAS--PYDHP-
 ..   . .|| ..| ||... | .|....  .. .  .  ..   .| ... ..  || .    ..... |.  ..| .|.|||..||  .     .| 
laetlvlvlkRPyvdeFLkkaaklfelvifTsaskkyad..tildllDpkrllkyrvlyRqdcrlvkgkllkddlsllkvdlskvviiDnseestlvnpe

NVINIGKFKSNSKD
| ..| ...|...|
nalkikpyisalsd
subfamily_DULLARD_pd Subfamily DULLARD 213-315 7.5e-09 27.5 In-house 44-147 (153) alignment 
Range on Protein: 213-315
Range on HMM: 44-147/153.0
KYPTLYKRAGLDFFLDHLRKDYEIYLYFNGNipQNKYEQLQFKIDTNGKYFTGLLYPETGIKERNQFSKKIEMLDRDPSKVIFIDAASPY---DHPNVIN
    .|||  .|.|||   | |.. ..  .   ..  ...  |.|..   ..  .| .  ..| ....|.. ... | |.|| .| ..        | |.
vlfyvykrPhvDlfLdvvskWydlviftasm..eeyaaavvdkLdsgrgilkrryyrqhCvlesgkytkdlslvssdlssviilDnspvayrknpdnaip

IGKFKS
|  . |
ikswls
subfamily_TIM50_pd Subfamily TIM50 217-320 1.4e-09 30.2 In-house 23-126 (126) alignment 
Range on Protein: 217-320
Range on HMM: 23-126/126.0
LYKRAGLDFFLDHLRKDYEIYLYFNGNIPQnkYEQLQFKIDTNGKYFTGLLYPETGIKErNQFSKKIEMLDRDPSKVIFIDAA---SPYDHPNVINIGKF
  || |.|.||..| . .|| .. . .. .    .|  |.| ..     |.   |  ..  .  | ...|.|| |||| .|        .. |.... |.
fkkrPgvdafleqlaelfeivvftseqglt..aaplidkldPkqlimyrlfrdatkyvd.Gehvkdlsklnrdlskvivvdldkksvklqpenalalkkw

KSNSKDK
. |..||
eGnaddk
subfamily_CTDSPL2_pd Subfamily CTDSPL2 220-300 2.2e-06 19.8 In-house 41-119 (142) alignment 
Range on Protein: 220-300
Range on HMM: 41-119/142.0
RAGLDFFLDHLRKDYEIYLYFNGNipQNKYEQLQFKIDTNGKYFTGLLYPETGIKERNQFSKKIEMLDRDPSKVIFIDAAS
|  |  ||... | .|. |.   .  .   ..|   .| . |..   |. |  .   ... |....| || .|.| .| ..
rpflreflervsklfevilftask..kvyadklldlldpekklikhrlfrehcvcvdgnyikdlsilGrdlektiivdnsp