Gene DDB_G0271690 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily FCP1
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP061_AA protein Get Run
DdisP061_AA_133-283 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Biotin_lipoyl Biotin-requiring enzyme 12-75 1.7e-07 18.3 Pfam-A 13-73 (74) alignment 
Range on Protein: 12-75
Range on HMM: 13-73/74.0
EPGKLQQWRYSVGDKFDKGSIIGIFNSSKNQSELNliSQYDGIIKSILINDTKKeLNKGDELYN
. |.  .. ..||||  .| .. .  . | . |..  .. .|..|.||... .. .. || |  
kegtvvevlvkvGdkVkagqvlaeveamKmemeie..apkaGvvkeilvkeGdt.vevgdllak
zinc-ribbons_6 zinc-ribbons 64-98 7e-06 12.3 Pfam-A 8-42 (70) alignment 
Range on Protein: 64-98
Range on HMM: 8-42/70.0
KKELNKGDELYNIEYCTHDIQFSGLCATCGRELTD
..||.. .| .  |.|..|.. ..|| .|..||  
qseleskgeeahCeaCqkdfkkealCpdCeqeLek
CPDc_SM00577 134-283 5.7e-38 122.2 In-house 1-143 (146) alignment 
Range on Protein: 134-283
Range on HMM: 1-143/146.0
KKLSLVLDLDHTVIHAVTEQGFNSSPEWRNKDKNKNgihtitvngpMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESsIFKERIL
||. ||||||.|..|. .... .| .|....|.  .          ... ..|||.. .||....| .||.|.|.....||..|..|.||.   .|.|.|
kkkvLVlDLdetLvhsanmaepksfsevsptdslae..........tlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkr.llkyrvl

SRDDGNGIN---FKSLQRLFPCDDSMVLIVDDRSDVWKKSK-NLIQISPYVYFT
.|.|    .   .|.. .|...|.|.|.|.|....... .. |...|.||... 
yRqdcrlvkgkllkddlsllkvdlskvviiDnseestlvnpenalkikpyisal
subfamily_FCP1_pd Subfamily FCP1 135-283 3.3e-58 187.9 In-house 1-146 (146) alignment 
Range on Protein: 135-283
Range on HMM: 1-146/146.0
KLSLVLDLDHTVIHAVTEQGFnSSPEwrnkdKNKNGIHTITV-NGPMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKERIL
|| ||.|||.|.||..... . ...|     ..|..|...|. . ...|..|.||.| .||....|.|||||||||||.||..|||..|||...|.||||
klvLvvDlDqtlihttkdpti.evke.....ekkkdikkftlpeekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfseril

SRDD--GNGINFKSLQRLFPCDDSMVLIVDDRSDVWKKSKNLIQISPYVYFT
|||.   .  ..|.|..|||.|||||.|.|||.|||....|||...||..|.
srdelldassktkklkklfptddsmvviiDDredvWnfaenlikvkpykffk
NIF NLI interacting factor-like phosphatase 137-302 7.8e-30 95.9 Pfam-A 2-153 (159) alignment 
Range on Protein: 137-302
Range on HMM: 2-153/159.0
SLVLDLDHTVIHAVTEQGFnsspewrNKDKNKNgihtitvNGPMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFkERILSRD
 ||||||.| .|.....         ..|..|        .  ... .||||.| .||.|..|.||. |.|.....||... . .||.. .| ...|.|.
tLVLDLDetLvhskekkdl.......kedgkkv.......eektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklf.kkrlyre

DG---NG-InFKSLQRLFPcDDSMVLIVDDRSDVWKK-SKNLIQISPyvYFTDVvDS--LHHEKQPLLqQKLK
.    || .  |.|. |   | | |.||||.......  .|.|.|.|  .. |  |.    ..  |.| ..|.
sctlrngky.vKdLsllgr.dlsrvvivDdsprsfelqpdngipiep..fygds.dkdtellkllpfl.eale
subfamily_DULLARD_pd Subfamily DULLARD 137-281 7.6e-20 63.2 In-house 3-147 (153) alignment 
Range on Protein: 137-281
Range on HMM: 3-147/153.0
SLVLDLDHTVIHAVTEQGFNSspEWRNKDKNKNGIHTITVNGPMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKERILSRD
 |||||| |.||. ...  .|  . ... ...  .. .  . |... . ||||.  ||. | | |.| |.| ....||....  .| . .|.|.|    .
tlvlDlDetlihsahdsvtks..tvkpgtapdfvvkvlidkepvlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqh

D--GNGINFKSLQRLFPcDDSMVLIVDDRSDVWK-KSKNLIQISPYVY
    .|   |.|  . . | | |.|.|. .  .. . .| |.|. ...
Cvlesgkytkdlslvss.dlssviilDnspvayrknpdnaipikswls
subfamily_CTDSPL2_pd Subfamily CTDSPL2 137-264 7.1e-14 44.0 In-house 1-119 (142) alignment 
Range on Protein: 137-264
Range on HMM: 1-119/142.0
SLVLDLDHTVIHAVTEQGFNSSPEWRnkdknkngihTITVNGPMNYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKERILsRD
||||||| |..|. .|.  ... ...              |  ..  ...||.| .|| .| |..|. ..|  .. ||... .|.|||   .| |.  |.
slvldldetlvhcslekleeatltfp..........vlfenktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlf.re

DGNGIN---FKSLQrLFPCDDSMVLIVDDRS
.   ..    | |. ..  | . ..|||. .
hcvcvdgnyikdls.ilGrdlektiivdnsp
subfamily_SCP_pd Subfamily SCP 138-263 2.9e-09 28.8 In-house 3-118 (142) alignment 
Range on Protein: 138-263
Range on HMM: 3-118/142.0
LVLDLDHTVIHAVteqgFNSspeWrnkdKNKNGIHTITVNGPM-NYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPEsSIFKERILSRD
||.||| |..|.     |.         || . . .. ..| . .  . ||||. .|| .|....|. ..|    .||. .| |.| . .....|..   
lvidldetlvhss....fkp...v....knadfvvpveidgtvhqvyvlkrphvdeflkrvgelfevvlftaslakyadpvadlldkk.kvlrarlfres

--DGNGINFKSLQRLFpCDDSMVLIVDDR
    .|   | | ||   | . |.|||. 
cvfhkgnyvkdlsrlg.rdlkkviivdns
Popeye Popeye protein conserved region 138-210 6.2e-07 15.7 Pfam-A 58-132 (153) alignment 
Range on Protein: 138-210
Range on HMM: 58-132/153.0
LVLDLDHTVIHAVTEQGFNSSPEWRNKDKNKNGIHTITV--NGPMNYCIKKRPHLVKFLTEVNKIYELHIYTMGT
.   |.  ..| .    |  ||||.    ...|.  .|.  .   .| . .| .|  .|.. . ...|  . .|.
ikvslegqfLhyifpfqflDsPeweslrpseegafqvtltadedcrylsWrrkkLklllakerylarlfsvllgk
subfamily_TIM50_pd Subfamily TIM50 181-279 3.9e-09 28.7 In-house 20-119 (126) alignment 
Range on Protein: 181-279
Range on HMM: 20-119/126.0
NYCIKKRPHLVKFLTEVNKIYELHIYTMGTRNYANEIAKLIDPESSIFKEriLSRDD---GNGINFKSLQRLFpCDDSMVLIVDDR-SDVWKKSKNLIQI
 .  |||| . .|| .. . .|. ..|  .  .|...   .||.. |  .  | ||     .| . | |. |   | | |..||   . | .. .| ...
GwrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldPkqlimyr..lfrdatkyvdGehvkdlskln.rdlskvivvdldkksvklqpenalal

SPY
...
kkw
PTCB-BRCT twin BRCT domain 440-504 2.3e-12 36.4 Pfam-A 3-63 (63) alignment 
Range on Protein: 440-504
Range on HMM: 3-63/63.0
IVFSGVYPLGtpiqKQPLRWLAEEFGSVVQNDINNETTHVIAQRKGTSKVNKALSKGLKVISPQW
|..||...      .. |. |....|  .. |.....||.|..|....|. || . |..|.||.|
icvsgysgdd....rkrlqkliralGasiskdltkkvTHLickraegeKyekAqkwgipvVspeW
BRCT BRCA1 C Terminus (BRCT) domain 455-508 1.1e-12 37.6 Pfam-A 22-77 (78) alignment 
Range on Protein: 455-508
Range on HMM: 22-77/78.0
QPLRWLAEEFGSVVQNDINNETTHVIAQRK--GTSKVNKALSKGLKVISPQWLIES
  |. |..|.|  |..... .|||.....   .|.|...|.... ......||...
eeleelikelGGkvstevskktthlvvgepelrtlkylaaialnipivneeWlldc