Gene DDB_G0268680 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP069_AA protein Get Run
DdisP069_AA_379-591 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_pats1_pd Subfamily pats1 61-112 1.7e-06 18.7 In-house 244-295 (691) alignment
Range on Protein: 61-112
Range on HMM: 244-295/691.0
ELTDNTKKNQIPVNNNNNNNNNNNNNNNNNNNNNNNNNIINNVNENYNSSKN
.. .. ..||.  ..|||||||||||.|||||||||||  || |.| |.. .
qihqqmqqnqlnsssnnnnnnnnnnnsnnnnnnnnnnnnnnnnnnnnnnnns

PhoD PhoD-like phosphatase 332-417 4.2e-07 20.3 Pfam-A 63-149 (453) alignment
Range on Protein: 332-417
Range on HMM: 63-149/453.0
VNWVHIEGLQPKTSYYFTCGTW-KNGFSHERKFKTQSDNPKDGYSFVVGGDVDITADAATLLKTSALK-NPDFAMIGGDLAYDHAQyT
   | ..||.|...|..   .  ..  |.  ...|  ..  .  ...| ..  ...   . ... | | ..|| .  ||  | ... .
tvkvevtgLepgqeyfYrfraeegesespvGrtrTlpeaaveslrlavvSCsnyeqGyfnayrelaekedlDfvlhlGDyiYeyge.g

subfamily_ACP5_pd Subfamily ACP5 380-592 1.6e-27 88.7 In-house 3-189 (189) alignment
Range on Protein: 380-592
Range on HMM: 3-189/189.0
GDVDI--TADAATLLKTSALKNPDFAMIGGDLAYDHAQytcyriVDKWLNNWQYKMISATGYTIPLIASIGNHEVIGdydapshripFFK-RyfpqMTKR
||...  .|..|||||... .. |.... |||||....       ...........|. . ...|...||||||.             |. .    ... 
gDlgvseaaslatllkeeeaneldliihvGDlaYalka......kneavwdefmnlieplaskvPymvsiGnhesds..........nfsay....kkrf

EDPgdgnnvD--DrktYNTINIGGPNGTViFNLDSGhHSSLSEQAIWMNQQLSSSPsssssmNFNSTQLRFSIYHVPMYPT---IREYsNPKSTAIRDN-
..|      .  .   . ....|. . .. .. .   .|  |||  |....|..        | ..|.  . ..| ||| .    ... . ..|..|.. 
smp......skne...wYsfdygpvhfis.lstevd.fslgseqykWLekdLkean......nrkktpwiivmgHrPmYcsnkdeddc.tkeetlvrkgl

---WLSTFDKFKFNIAFENHDHAYK
     ....|.|...|...|.|.|.
resledllykykvdlalsgHeHsYe

PAPL 380-591 2.4e-09 29.6 In-house 4-194 (194) alignment
Range on Protein: 380-591
Range on HMM: 4-194/194.0
GDVDITADAA--TLLKTSALKNPDFAMIGGDLAYDHAQYtcyrivDKWLNNWQYKMISATGYTIPLIASIGNHEVigDYDAPSHRipffkRYFPQMTKRE
|| . |  ..  .| |. . .. |. .. |||||.  .       ..| .  ....|.    ..|. ...||||   .|.  ...     ..| .....|
GDlGqtnasslkrlqketqkgkydailhvGDlaYaddeq......newdgdefmrqieplaasvpymvapGNHEe..eynfsnyk.....arfsmpgsee

dpgdGNNVDDRKTYNTINIGGPNGTVIFNLDSGHHSSLSEQAIWMNQQLSSSpsssssmNFNSTQLRFSIYHVPMYPTIREYSN-PKSTAIRDNWLSTFD
    |..   ....|.. .      .|.. .. . .. |||  |....|..        | . |   . . | ||| .  . ..  .. .....    . 
....gesnssesgsnsysfetesvhfivlsseedvkekseqyewleedlakv.......nRsktPWiivmgHrpmYcsnkdkddckekakmlaaledlly

KFKFNIAFENHDHAY
| . .. .  | |.|
kygVDlvlaGHeHsY