Gene DDB_G0281861 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP071_AA protein Get Run
DdisP071_AA_315-501 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 316-502 9.7e-60 193.7 In-house 19-189 (189) alignment 
Range on Protein: 316-502
Range on HMM: 19-189/189.0
DPSQTPFWSVHHIGDISYARGK--AFIWDYFMDSMQPIVSKVPYMVSIGNHEYDFigqpfapSWSNYgsdsggecgvpySKRFHMTgaedsTRNLWFSYE
. ... .  ..|.||..||...  . .|| ||....|..|||||||||||||.|        ..|.|            .|||.|.     ..| |.|..
eeeaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesds.......nfsay............kkrfsmp.....sknewYsfd

NGPIHFTVMSAEHDFLPGSPQFEWLNNDLASV-DREKTPWVIFSGHRPLYTSALPEDSI-GSITA----LREAIEPLFQKYDVDMALWGHVHIYE
 ||.||...|.|.|| .||.|..||..||... .|.||||.|. ||||.|.|   ||..  . |.    |||..|.|..||.||.||.|| |.||
ygpvhfislstevdfslgseqykWLekdLkeannrkktpwiivmgHrPmYcsnkdeddctkeetlvrkglresledllykykvdlalsgHeHsYe
PAPL 316-501 1.2e-45 148.0 In-house 20-194 (194) alignment 
Range on Protein: 316-501
Range on HMM: 20-194/194.0
DPSQTPFWSVHHIGDISYARGKAFIWDYFM--DSMQPIVSKVPYMVSIGNHEYDFIGQPFAPSWSNYGsdsgGECGVPYSKRFHMTGaedstrnlwFSYE
. ... . .. |.||..|| ..   || .   ....|....|||||..||||...  ..   ..|..|    .|.|  .|...  .          .|.|
etqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeeynfsnykarfsmpg....seegesnssesgsns.........ysfe

NGPIHFTVMSAEHDFLPGSPQFEWLNNDLASVDREKTPWVIFSGHRPLYTSALPEDSIGSITALREAIEPLFQKYDVDMALWGHVHIY
... ||.|.| |.|. . | | |||..|||.|.|.||||.|. ||||.|.|   .|. ..  . ..|.|.|..|| ||. |.||.| |
tesvhfivlsseedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdkddckekakmlaaledllykygVDlvlaGHeHsY
Metallophos Calcineurin-like phosphoesterase 327-501 3.7e-19 62.8 Pfam-A 37-200 (200) alignment 
Range on Protein: 327-501
Range on HMM: 37-200/200.0
HIGDISYARGKAFIWDYFM-DSMQPIVSKVPYMVSIGNHEYDFIGQPFAPSWSN-YGSDSGGECGVPYSKRfhmtgaedstrnLwFSYENGPIHFTVMSA
. ||....   .  .   .  .....  ..|... .||||.|...... .     .  .  . . ..|. .            .     ..   ... | 
flGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangeeeyenl............k.itllttsgelyglsg

EHDFLPGSPQFEWLNNDLASVDREKTPWVIFSGHRPLYTSALPEDSIGSITALREAIEPLFQKYDVDMALWGHVHIY
.. .|..| | |.|. .|| ..|......|. .|.||. |   .| |||    ..| |.|..||.||. |.||.| .
lypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddigselfgpdalekllekygvdlvlrGHtHkp
ACP5 329-499 4.9e-09 28.1 In-house 38-197 (198) alignment 
Range on Protein: 329-499
Range on HMM: 38-197/198.0
GDISYARGKAFIWDY-----FMDSMQPIVSKVPYMVSIGNHEYDfiGQPFAPSWSNYGSDSGGECGVPYSKRFHMTGAEDSTRNLWFSYENGPIHFTVMS
||  |  | . . |      | .  .    .||..| .|||.|   |.. |       |..     . ||.... .  |  | . ......   .   ..
GDnfyddGvtsvddprfkesfekiytakslqvpWyvvlGNHDyr..gnvsaqieyakrskdsrfpslryslskkevvtelftekkdeksdqrevaereky

AEHdflpgspQFEWLNNDLASvdrEKTPWVIFSGHRPLYTSAlpedSIGSITALREAIEPLFQKYDVDMALWGHVH
||.       | .||.. ||.   ... |.|  || |.|. .    . |. . | | ..||..||.||. | || |
aee.......qlkwlekalak...stadwkiVvGHhpvySig....ehgdtkelverllpllkkykvdaYlnGHdH
subfamily_PAPL_pd Subfamily PAPL 427-499 3.6e-09 28.1 In-house 145-210 (212) alignment 
Range on Protein: 427-499
Range on HMM: 145-210/212.0
DFLPGSPQFEWLNNDLASvdrEKTPWVIFSGHRPLYTSAlpedSIGSITALREAIEPLFQKYDVDMALWGHVH
|    . |..||...|..   ..  ..| .|| |..  |    . |. . |.. ..|| .||.|.  | || |
dvslaeeqwawleeeLka...seadylivaGhypvwsva....ehGptkiLvkrLkPlLekynvtaylsGhDh
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 520-590 1.7e-14 45.3 Pfam-A 2-62 (62) alignment 
Range on Protein: 520-590
Range on HMM: 2-62/62.0
GTVHVIIGMAGNtysvpweG-SDissgnGHEDEPEWSIFRSISYGHVRF-YANTTSLYFEFVGNHRSIVHDSF
..||...|.|||       | |.       . .|||| ||. .||..|.  .| | |..||| .    |.|||
ApvhIvvGaAGn.......glsk.....fskpqpewsafresdyGysrltvvNrthLhwefvrsddgqvlDsf