Gene DDB_G0285351 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP072_AA protein Get Run
DdisP072_AA_96-364 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 161-365 1.1e-63 206.5 In-house 2-189 (189) alignment 
Range on Protein: 161-365
Range on HMM: 2-189/189.0
FGDMGYIDGDSLNSDWYTInnlksISNQLSFVTHVGDIAYADYSkdskyyGNETIWNNFLSSINSITSTLPYMTTPGNHDSFgDEFSAYSKTWQMPtehH
|||.|. ...||.. ...       .|.|....||||.|||. .       ||..|..|...|....|..|||...|||.|. ..||||.|...||   .
fgDlgvseaaslatllkee.....eaneldliihvGDlaYalka......kneavwdefmnlieplaskvPymvsiGnhesd.snfsaykkrfsmp...s

SNNWYSFDYNGVHFISISSEDTYIPLSDQHSWIENDLKQYRNSNPNGWLIMYSHRPFYCNAKFGWCNdDYKDEKTSKRlYIDSLEYLLYKYNVDLFISGH
.|.||||||..|||||.|.|... . |.|..|.|.|||...|.. . |.|.. |||.||. | ..   ....  ..|  ...||| |||||.|||..|||
knewYsfdygpvhfislstevdfslgseqykWLekdLkeannrkktpwiivmgHrPmYcsnkdeddc.tkeetlvrkg.lresledllykykvdlalsgH

CHAYE
 |.||
eHsYe
PAPL 161-364 1.8e-39 127.9 In-house 3-194 (194) alignment 
Range on Protein: 161-364
Range on HMM: 3-194/194.0
FGDMGYIDGDSlnsdwYTINNLKSISNQLSFVTHVGDIAYADYSKdskyygNETIWNNFLSSINSITSTLPYMTTPGNHDSFGDeFSAYSKTWQMPTEH-
|||.|. . .|      .  . .  ....... ||||.||||...      ||.   .|. .|.......|||..||||..  . ||.|.....||... 
fGDlGqtnass.....lkrlqketqkgkydailhvGDlaYaddeq......newdgdefmrqieplaasvpymvapGNHEeeyn.fsnykarfsmpgsee

-HSN------NWYSFDYNGVHFISISSEDTYIPLSDQHSWIENDLKQYrNSNPNGWLIMYSHRPFYCNakfgwcnDDYKDEKTSKRLYIDSLEYLLYKYN
  ||      | |||....|||| .|||. . . |.|  | |.||..  | . . |.|.. |||.||.       .. ||....|. . ..|| |||||.
gesnssesgsnsysfetesvhfivlsseedvkekseqyewleedlakv.nRsktPWiivmgHrpmYcs.......nkdkddckekakmlaaledllykyg

VDLFISGHCHAY
|||...|| |.|
VDlvlaGHeHsY
Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 184-368 5.7e-08 24.9 Pfam-A 22-125 (156) alignment 
Range on Protein: 184-368
Range on HMM: 22-125/156.0
SIsNQLSFVTHVGDiayadyskdskYYGNetiwNNFLSSINSItstlPYMTTPGNHDsfgdefsayskTWQMPTEHHSNNwysfdyngvhfisissedty
 | ..  .. |.||           ...     . ..  ...|    |  . .||||            ...|.| . .                     
di.kevdlilhaGD...........lvep....eevvelledi....pvlavrGnhD...........eaelpkelavel....................

iplsdqhswiendLKQYRNSNPNGWLIMYSHRPFYCnakfgwcnddykD-----EktskrlyidsLEYLLYKYNVDLFISGHCHAYETSK
             |... ... .|. .. .|. ..             .     |          |..|| ....||...|| | ... |
.............llaaaaleiegdrvllvhgtpls............vqsseee..........laellkeagadlvflGHtHkpkvek
subfamily_PAPL_pd Subfamily PAPL 187-363 2.4e-10 32.0 In-house 33-211 (212) alignment 
Range on Protein: 187-363
Range on HMM: 33-211/212.0
NQLSFVTHVGDIAYADYSKDSKYYGNETIWNNFLSsINSItsTLPYMTTPGNHDSFGD-----EFSAYSKTWQMPTEHHSNNWYSFDY-NGVHFISIS--
 .  || ..||. | .  || .    .. ...  .  .|.  . |... .||||  |.     ..|  || |..|. ......   |  . |... |   
leaqfvlalGDnfYekGvkdvddarfketfedvft.aesl..qvpwyvvagnHDykGnvsaqiaYsklskrWkfpslyytksfkipdsnatvqlvlidtv

-----SED-------TYIPLSDQHSWIENDLKQyrnsNPNGWLIMYSHRPFYCNAKFGwcnddykdektSKRLYIDSLEYLLYKYNVDLFISGHCHA
     |.|            ..|..|.|..||.    . . .||.  | | .  |. |           . .   ..|. || ||||. ..||| | 
llcgksddlklegpvdvslaeeqwawleeeLka....seadylivaGhypvwsvaehG...........ptkiLvkrLkPlLekynvtaylsGhDhn
ACP5 187-362 5.7e-09 27.9 In-house 29-197 (198) alignment 
Range on Protein: 187-362
Range on HMM: 29-197/198.0
NQLSFVTHVGDIAYADYSKDSKYYGNETIWNNFLssiNSITSTLPYMTTPGNHDSFGDEFSAYSKTWQMPTEHHSNNWY-------SFDYNGVHFISISS
....||  .||  | |  .. .    .. ....    .. .  .|.... ||||  |.  .  ... .  ...  ...|         ...  .  . |.
ldidfvlslGDnfyddGvtsvddprfkesfekiy...takslqvpWyvvlGNHDyrgnvsaqieyakrskdsrfpslryslskkevvtelftekkdeksd

EDTYIPLSDQHSWIENDLKQYRNSNPNGWLIMYSHRPFYCNAKFGwcnddykdektSKRLYIDSLEYLLYKYNVDLFISGHCH
...  . ......  ..|..  ... . |.|   | | |  .. |           ...  ...|. || ||.||....|| |
qrevaerekyaeeqlkwlekalakstadwkiVvGHhpvySigehg...........dtkelverllpllkkykvdaYlnGHdH
Metallophos Calcineurin-like phosphoesterase 190-364 1.5e-09 31.4 Pfam-A 33-200 (200) alignment 
Range on Protein: 190-364
Range on HMM: 33-200/200.0
SFVTHVGDIAYADYSKDSKYYGNEtiwnnflSSINSITSTLPYMTTPGNHDSFGDEFSAYSKTWQMPTEHHSNNWYSFDY---------NGVHFISISSE
 .| . ||. ...   .               . . ..   |.. ..|||.|.. ..  . .  | .     .| .  .          .|. . . ...
dlvlflGDlvdrgdwssetlalld.......ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangeeeyenlkitllttsgelyglsgly

DTYIPLSDQHSWIEndLKQYRNSNPNGWLIMYSHRPFYCNAKF---GwcnddykdekTSKRLYIDSLEYLLYKYNVDLFISGHCHAY
  . .   .. ..|  . .  . ..... |  .|.|...  .    .           |   ..| || ||.||.||| ..|| | .
pllgdsaqeeqlee..flalplralvdgkilltHgplsssggsgddi..........gselfgpdalekllekygvdlvlrGHtHkp
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 383-447 3.5e-17 53.9 Pfam-A 1-62 (62) alignment 
Range on Protein: 383-447
Range on HMM: 1-62/62.0
KATVHCVIGTGGNkggQIEEWYEPKPWTNGLKSSLNGYALLNIINSTTLNWKFIANLNNSIIDEF
||.|| |.|..||   . ... .|.| .. ...| .||. |...|.|.|.|.|... .....|.|
kApvhIvvGaAGn...glskfskpqpewsafresdyGysrltvvNrthLhwefvrsddgqvlDsf