Gene DDB_G0293460 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP073_AA protein Get Run
DdisP073_AA_133-354 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PhoD PhoD-like phosphatase 81-180 1.8e-09 28.1 Pfam-A 61-153 (453) alignment 
Range on Protein: 81-180
Range on HMM: 61-153/453.0
GHPTTAILTGLQEMTQYFYSIGNKHSDEYSEVFNFTTGkinqIGGQVTPFSLSIFGDMGYGgKGLdsdFYTVANLYERsNDLAFNIHVGDIAYADE--TW
 . ... .|||.  ..||| .  ..... |.| ...|      ...|. ..| ..... |  .|    | . ..| |. .|| | .|.||. |...  |.
dytvkvevtgLepgqeyfYrfraeegesespvGrtrTl....peaaveslrlavvSCsnye.qGy...fnayrelaek.edlDfvlhlGDyiYeygegty

ET
..
kn
subfamily_ACP5_pd Subfamily ACP5 134-335 8e-64 207.0 In-house 1-189 (189) alignment 
Range on Protein: 134-335
Range on HMM: 1-189/189.0
IFGDMGYGGkgldSDFYTVANLYERSNDLAFNIHVGDIAYADETwetainGNQTIWNQFLDSINPVSSHLIYMTCPGNHDIFYDLSVYRRTWLMPtdD--
.|||.|.      .. .. ..  |..|.| . |||||.|||...       |...|..|...|.|..|.. ||...|||. ....| |.... ||  .  
vfgDlgvse....aaslatllkeeeaneldliihvGDlaYalka......kneavwdefmnlieplaskvPymvsiGnhesdsnfsaykkrfsmp..skn

NdqvsWYSFDYNGVHFVGISSEHDFLPLSPQHTWIENDLKNFRSNNPDNFIIMFAHRPFYCSTVWNW-CnTTEDYLKK-AFVYSLENLLYKYNVDMFISG
.    ||||||..|||...|.|.|| . |.|..|.|.|||...... ...||...|||.|||. ... | |.|..| . . ..|||.|||||.||...||
e....wYsfdygpvhfislstevdfslgseqykWLekdLkeannrkktpwiivmgHrPmYcsnkdeddc.tkeetlvrkglresledllykykvdlalsg

HTHSSE
|.|| |
HeHsYe
PAPL 134-333 1.4e-41 134.8 In-house 2-193 (194) alignment 
Range on Protein: 134-333
Range on HMM: 2-193/194.0
IFGDMGYGGKGLdsdfYTVANLYERSNDLAFNIHVGDIAYADETWetaingNQTIWNQFLDSINPVSSHLIYMTCPGNHDIFYDLSVYRRTWLMPTDDND
.|||.|.  .       .  .  ...... . .||||.||||...      |..   .|...|.|..... ||..||||.  |. | |.... ||.. . 
vfGDlGqtnass....lkrlqketqkgkydailhvGDlaYaddeq......newdgdefmrqieplaasvpymvapGNHEeeynfsnykarfsmpgseeg

Q-VSW------YSFDYNGVHFVGISSEHDFLPLSPQHTWIENDLKNFRSNNpDNFIIMFAHRPFYCSTVwnwcNTTEDYLKKAFVYSLENLLYKYNVDMF
.  |.      |||....|||. .|||.|. . | |  | |.||..   ..   .||...|||.|||.     .....  |......||.|||||.||..
esnssesgsnsysfetesvhfivlsseedvkekseqyewleedlakvnRsk.tPWiivmgHrpmYcsnk....dkddckekakmlaaledllykygVDlv

ISGHTHS
..|| ||
laGHeHs
ACP5 134-332 1e-10 33.6 In-house 3-197 (198) alignment 
Range on Protein: 134-332
Range on HMM: 3-197/198.0
IFGDMGYGGKGLDSDFYTVANLYERSNDLAFNIHVGDIAYADETWETAINGNQTIWNQFldsINPVSSHLIYMTCPGNHDIFYDLSVYRRTWLMPTDDND
..||.|  |.   |.  .  . . ...|. | . .||  | | . ..  .  .. ....    .  | .. .... ||||.  . |   .  .   | . 
vvGDwGrkgeynqsavakqmgkvaekldidfvlslGDnfyddGvtsvddprfkesfeki...ytakslqvpWyvvlGNHDyrgnvsaqieyakrskdsrf

QVSWYSFDYNGVHFVGISSEHDF----LPLSPQHTWIENDLKNFR---SNNPDNFIIMFAHRPFYCStvwnwCnttEDYLKKAFVYSLENLLYKYNVDMF
   .||.. . |    . ...|.        .... .|. ||. .   ...  ...| . | | |       .   |   .|  |..|. || ||.||..
pslryslskkevvtelftekkdeksdqrevaerekyaeeqlkwlekalakstadwkiVvGHhpvySi.....g...ehgdtkelverllpllkkykvdaY

ISGHTH
..|| |
lnGHdH
Metallophos Calcineurin-like phosphoesterase 135-333 3e-11 37.0 Pfam-A 6-199 (200) alignment 
Range on Protein: 135-333
Range on HMM: 6-199/200.0
FGDMGYGGKGLDsDFYTVANLYERSNDLAFNIHVGDIAYADETWETAINGNQtiwnqflDSINPVSSHLIYMTCPGNHDIFYDLSVYRRTWLMPTDDNDQ
.||...|   |. |.    .    ...  . .. ||. ...  ... .   .        . ....    .. ..|||. ..  |.|  . ... | ...
igDlHgglddle.dlllillkiaaeekpdlvlflGDlvdrgdwssetlalld.......ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrgl

VSWYSFDYN---------GVHFVGISSEHDFLPLSPQHTWIENDLKNFRsnNPDNFIIMFAHRPFYCSTVWN-WCnttedYLKKAFVYSLENLLYKYNVD
   .  . |         |. ... .....  .   .....| .... |  ......|  .|.|...|. .. .             . ||.||.||.||
angeeeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplr..alvdgkilltHgplsssggsgddi.....gselfgpdalekllekygvd

MFISGHTHS
. ..|||| 
lvlrGHtHk
Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 153-365 4e-07 22.2 Pfam-A 17-139 (156) alignment 
Range on Protein: 153-365
Range on HMM: 17-139/156.0
ANLYERSNDLAFNIHVGDIAYAdetwetaingnqtiwNQFLDSINPVSshliYMTCPGNHDifydlsvyrrTWLMPTDDNDQVswysfdyngvhfvgiss
  ..|. .. .. .|.||.                  ..... .. .       ...||||           . .|. .. ..                 
eavledikevdlilhaGDlvep...............eevvelledip....vlavrGnhD..........eaelpkelavel.................

ehdflplspqhtwiendlknFRSNNP---DNFIIMFAHRPFYCstvwnwcntteD-----YlkkafvysLENLLYKYNVDMFISGHTHSSERtlptyngq
                    .  ..    ... ... |. ..            .     .        |. || ....|....||||  .         
....................llaaaaleiegdrvllvhgtpls...........vqsseee........laellkeagadlvflGHtHkpkv........

pigtySNPKATIHITVGTGGN
        ..|.....|. |.
.....ekrggtlvvnpGsvge
subfamily_PAPL_pd Subfamily PAPL 260-333 4e-07 21.5 In-house 150-211 (212) alignment 
Range on Protein: 260-333
Range on HMM: 150-211/212.0
SPQHTWIENDLKNfrsnNPDNFIIMFAHRPfycstVWNWCNTTEdylKKAFVYSLENLLYKYNVDMFISGHTHS
. |..|.|..||.    . ....|.. | |     ||  ..       |  | .|. || ||||. ..||| |.
eeqwawleeeLka....seadylivaGhyp.....vwsvaehGp...tkiLvkrLkPlLekynvtaylsGhDhn
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 353-416 1.5e-21 67.9 Pfam-A 1-61 (62) alignment 
Range on Protein: 353-416
Range on HMM: 1-61/62.0
KATIHITVGTGGNseGNQHHWYPQPIWSsGYRISDNGFGLMNFINSTTLSWQFVANINNTIIDE
||..||.||..||  |... ..||| ||  .| ||.|.. ....|.|.|.|.||.. .....|.
kApvhIvvGaAGn..glskfskpqpews.afresdyGysrltvvNrthLhwefvrsddgqvlDs