Gene dduA in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP074_AA protein Get Run
DdisP074_AA_137-351 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
PAPL 138-339 2.5e-40 130.7 In-house 2-194 (194) alignment 
Range on Protein: 138-339
Range on HMM: 2-194/194.0
FFGDMGWIEGDSlnsdvYTVDNLISRINEIQILHHVGDIAYADKQKpynlpgNQTIWNKFQNSISPLSSHLPYLTCPGNHDRFIDLSVYTKTWQMPVDFE
.|||.|  . .|      .  .   . ...... ||||.||||...      |..   .| ..|.||....||...||||..  . | |.....|| . |
vfGDlGqtnass.....lkrlqketqkgkydailhvGDlaYaddeq......newdgdefmrqieplaasvpymvapGNHEeeynfsnykarfsmpgsee

S--DSW------YSYDYNGIHFVGFSSEHDYFPLSSQHTWIENDLKQYRKSNpNGWIVMYSHRPFYCSVvwdwcSNIDVVESKKIYLWSLEDLLYKYNVD
.   |.      ||..... ||. .|||.|. . | |  | |.||..  .|. . ||... |||.|||      .. |  ..|. .| .||||||||.||
gesnssesgsnsysfetesvhfivlsseedvkekseqyewleedlakvnRsk.tPWiivmgHrpmYcsn.....kdkddckekakmlaaledllykygVD

LFISGHAHSY
|...|| |||
lvlaGHeHsY
subfamily_ACP5_pd Subfamily ACP5 139-340 5.2e-66 214.2 In-house 2-189 (189) alignment 
Range on Protein: 139-340
Range on HMM: 2-189/189.0
FGDMGWIEGDSLNSDVYTVdnlisRINEIQILHHVGDIAYADKQkpynlpGNQTIWNKFQNSISPLSSHLPYLTCPGNHDRFIDLSVYTKTWQMPvdfES
|||.|. |..||.. ...      . ||.....||||.|||.|.       |...|..|.|.|.||.|..||....|||... ..| |.|...||   ..
fgDlgvseaaslatllkee.....eaneldliihvGDlaYalka......kneavwdefmnlieplaskvPymvsiGnhesdsnfsaykkrfsmp...sk

DSWYSYDYNGIHFVGFSSEHDYFPLSSQHTWIENDLKQYRKSNPNGWIVMYSHRPFYCSVVWDWCSNIDVVESKKIYLWSLEDLLYKYNVDLFISGHAHS
..|||.||...||...|.|.|... |.|..|.|.|||...... . ||... |||.|||  ...  . . . ..| .  |||||||||.|||..||| ||
newYsfdygpvhfislstevdfslgseqykWLekdLkeannrkktpwiivmgHrPmYcsnkdeddctkeetlvrkglresledllykykvdlalsgHeHs

YE
||
Ye
ACP5 140-337 3.9e-09 28.5 In-house 5-197 (198) alignment 
Range on Protein: 140-337
Range on HMM: 5-197/198.0
GDMGWiEGDSLNSDVYTVDNLISRINEIQILHHVGDIAYADKQKPYNLPGNQTIWNKFQNSispLSSHLPYLTCPGNHDRFIDLSVYTKTWQMPVDFESD
||.|  .| .  |.| .  . . . ..|..   .||  | |  .  . |  .. ..|....    | ..|.... ||||   . |   .  .   | .  
GDwGr.kgeynqsavakqmgkvaekldidfvlslGDnfyddGvtsvddprfkesfekiyta...kslqvpWyvvlGNHDyrgnvsaqieyakrskdsrfp

SWYSYDYNGIHFVGFSSEHDY--------FPLSSQHTWIENDLKQYRKSNPNGWIVMYSHRPFYCsvvwdwcsnIDVVESKKIYLWSLEDLLYKYNVDLF
| ... .. . .. .  |..          . ......  ..|..  ... . |..   | | |          |   ...|  . .|. || ||.||..
slryslskkevvtelftekkdeksdqrevaerekyaeeqlkwlekalakstadwkiVvGHhpvyS.........igehgdtkelverllpllkkykvdaY

ISGHAH
..|| |
lnGHdH
Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 156-366 2.8e-08 25.9 Pfam-A 15-135 (156) alignment 
Range on Protein: 156-366
Range on HMM: 15-135/156.0
TVDNLISRINEIQILHHVGDIAYadkqkPynlpgnqtiwnkfqNSISPLSSHLPYLTCPGNHDrfidlsvytktwQ----------Mpvdfesdswysyd
... .. .|.|.... |.||.       |              ... .| ...| |...||||            .          .             
aleavledikevdlilhaGDlve.....p..............eevvelledipvlavrGnhD............eaelpkelavel.............

yngihfvgfssehdyfplssqhtwiendLKQYRKSNPNGWIVMYSHRPFYCsvvwdwcsnidvvesKKIYLWSLEDLLYKYNVDLFISGHAHSYERtlpv
                            |... ... .|. |. .|. ..                 . .   |. || ....||...|| | ..     
............................llaaaaleiegdrvllvhgtpls...............vqsseeelaellkeagadlvflGHtHkpkv....

fknkimgdvESPKATVHIVVG
         |. ..|.....|
.........ekrggtlvvnpG
subfamily_PAPL_pd Subfamily PAPL 165-338 4.1e-07 21.4 In-house 33-211 (212) alignment 
Range on Protein: 165-338
Range on HMM: 33-211/212.0
NEIQILHHVGDIAYADKQKPYNlpgNQTIWNKFQNSISPLSSHLPYLTCPGNHDR------FIDLSVYTKTWQMPVDFESDSWYSYDY-NGIHFV-----
 | |.  ..||. | .  |  .   .. . ..|..  .  | . |.....||||        |. |  .| |..|  . . |.   |  . ...|     
leaqfvlalGDnfYekGvkdvd...darfketfedvftaeslqvpwyvvagnHDykGnvsaqiaYsklskrWkfpslyytksfkipdsnatvqlvlidtv

---GFS------SEHDYFPLSSQHTWIENDLKQyrksNPNGWIVMYSHRPfycsvVWDWCSNidvvESKKIYLWSLEDLLYKYNVDLFISGHAHS
   | |        .|    ..|..|.|..||.    . . ....  | |     ||  ...     . ||   .|. || ||||. ..||| |.
llcgksddlklegpvdvslaeeqwawleeeLka....seadylivaGhyp.....vwsvaeh....GptkiLvkrLkPlLekynvtaylsGhDhn
Metallophos Calcineurin-like phosphoesterase 166-339 1.2e-11 38.3 Pfam-A 31-200 (200) alignment 
Range on Protein: 166-339
Range on HMM: 31-200/200.0
EIQILHHVGDIAYADKQKPYNLPGNQtiwnkfqNSISPLSSHLPYLTCPGNHDRFIDLSVYTKTWQMPVDFESDSWYSYDY----------NGIHFVGFS
..... . ||. ....   . |   .       ..  .|.   |.  ..|||. .   |.|  .  .. | .   .....|          .|  ... .
kpdlvlflGDlvdrgdwssetlalld.......ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangeeeyenlkitllttsgelyglsg

SEHDYFPLSSQHTWIENDLKQyrKSNPNGWIVMYSHRPFYCSV-VWDWCsnidvvESKKIYLWSLEDLLYKYNVDLFISGHAHSY
.......   .....| ...   . .......  .|.|...|   .|.       .|   .   ||.||.||.||| ..|| | .
lypllgdsaqeeqleeflalp..lralvdgkilltHgplsssggsgddi......gselfgpdalekllekygvdlvlrGHtHkp
GvpO Gas vesicle synthesis protein GvpO 301-342 1.4e-06 14.6 Pfam-A 52-91 (101) alignment 
Range on Protein: 301-342
Range on HMM: 52-91/101.0
DWCSNIDVVESKKIYlwSLEDLLYKYNVDLFISGHAHSYERT
.|. ...|||...|   . .|||  |.| |  .|.  .|.|.
gwrveveVvErarip..dtqdllasYeveLdaegellgYrrv
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 358-422 3.6e-21 66.7 Pfam-A 1-62 (62) alignment 
Range on Protein: 358-422
Range on HMM: 1-62/62.0
KATVHIVVGTGGDveGEDMIWQPSQQWTtGLRTSINGFGLLNVINSTTLNWQFVANINNTIIDEF
||.||||||..|   |..  ..| ..|.  .|.| .|.. |.|.|.|.|.|.||.. .....|.|
kApvhIvvGaAGn..glskfskpqpews.afresdyGysrltvvNrthLhwefvrsddgqvlDsf