Synonym: CG12313, Dmel\CG12313, Dmel_CG12313, ttm2
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
NIF | NLI interacting factor-like phosphatase | 210-357 | 3.8e-37 | 119.6 | Pfam-A | 1-159 (159) | alignment | ||
Range on Protein: 210-357
Range on HMM: 1-159/159.0
YTLVLEIKDVLVHPDWTY-----------ETGWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDP-NGCIMYRLVRDSTHFDGGHHVKNLD
.||||.. ..||| ... .| ...|||||.| ||||..|..|.|..||.. .. |..|.||| . . .|| |.|. . |..||.|.
ktLVLDLDetLvhskekkdlkedgkkveektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyvKdLs
NLNRDLKRVVVVDWDRNSTKFHPSNSFSIPRWSGN-DNDTTLFELTSFLSVLGtSEiDDVR
|.|||.|||.|| ...| ...|.| |... |. |.||.| .|..||. | . ||||
llgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpfleale.ks.ddvr
|
|||||||||
CPDc_SM00577 | 210-335 | 7.8e-32 | 102.3 | In-house | 3-145 (146) | alignment | |||
Range on Protein: 210-335
Range on HMM: 3-145/146.0
YTLVLEIKDVLVHP----------DWTYE-----TGWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGCIMYR-LVRDSTHFDGGHHV
..|||.....||| ... . | ....|||.|| |||..||.||.|..|... .. ...|.|||.. ..|| |.|..... |...
kvLVlDLdetLvhsanmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkrllkyrvlyRqdcrlvkgkll
KN-LDNLNRDLKRVVVVDWDRNSTKFHPSNSFSIPRWSGNDND
|. |. |..||..||..| ...||...|.| . |.... . .|
kddlsllkvdlskvviiDnseestlvnpenalkikpyisalsd
|
|||||||||
subfamily_TIM50_pd | Subfamily TIM50 | 211-336 | 2e-64 | 207.4 | In-house | 1-126 (126) | alignment | ||
Range on Protein: 211-336
Range on HMM: 1-126/126.0
TLVLEIKDVLVHPDWTYETGWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGCIMYRLVRDSTHFDGGHHVKNLDNLNRDLKRVVVVD
|||||.|||||||.|||.||||||||||||.||...|..|||||.|.|||.|..||.|.|||...|||||.||.|.. |.|||.|..|||||..|.|||
tlvlelkdvlvhpewtyktGwrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvd
WDRNSTKFHPSNSFSIPRWSGNDNDT
.|..|.|..|.|.... .|.||..|.
ldkksvklqpenalalkkweGnaddk
|
|||||||||
subfamily_DULLARD_pd | Subfamily DULLARD | 229-336 | 5.8e-19 | 60.3 | In-house | 44-152 (153) | alignment | ||
Range on Protein: 229-336
Range on HMM: 44-152/153.0
TGWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNG-CIMYRLVRDSTHFDGGHHVKNLDNLNRDLKRVVVVDWDRNSTKFHPSNSFSIP
. .. ||| ||.||. .|....|..|| . ..|| || . . |. |.. . |...|.| .. ||..|...| .. ...| |. |
vlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvlesgkytkdlslvssdlssviilDnspvayrknpdnaipik
RWSGNDNDT
| ...||
swlsdpsdt
|
|||||||||
subfamily_FCP1_pd | Subfamily FCP1 | 230-314 | 1e-08 | 27.4 | In-house | 42-127 (146) | alignment | ||
Range on Protein: 230-314
Range on HMM: 42-127/146.0
GWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGCIMY-RLVRDSTHFDGGHHVKNLDNL-NRDLKRVVVVDwDRN
. |.||.. ||.. .|..|. .|| .. . .. |||.. . |.. .| ...|.|..| ..| . ||..| ||.
vyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrdelldassktkklkklfptddsmvviiD.Dre
|
|||||||||
subfamily_CTDSPL2_pd | Subfamily CTDSPL2 | 233-335 | 3.9e-19 | 61.0 | In-house | 38-141 (142) | alignment | ||
Range on Protein: 233-335
Range on HMM: 38-141/142.0
FKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGC-IMYRLVRDSTHFDGGHHVKNLDNLNRDLKRVVVVDWDRNSTKFHPSNSFSIPRWSG
..|| . ||.. .| ||....|| . | |.| |||. | .|| |.. . | ..|.|. | |||.....|| .. . .| | |
vrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyikdlsilGrdlektiivdnspqafayqlenGipieswfe
NDND
..||
dend
|
|||||||||
subfamily_SCP_pd | Subfamily SCP | 234-336 | 2.8e-24 | 77.5 | In-house | 40-142 (142) | alignment | ||
Range on Protein: 234-336
Range on HMM: 40-142/142.0
KKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGCIMYRLVRDSTHFDGGHHVKNLDNLNRDLKRVVVVDWDRNSTKFHPSNSFSIPRWSGND
||| || |||. .. ||.|..|| |..| || .. . .|| |.| .| | .||.| .| ||||.|..|| .| ||| |. . | .
lkrphvdeflkrvgelfevvlftaslakyadpvadlldkkkvlrarlfrescvfhkgnyvkdlsrlgrdlkkviivdnspasyifhpenavpveswfddk
NDT
.||
edt
|
|||||||||
DUF2840 | Protein of unknown function (DUF2840) | 306-343 | 3.9e-06 | 12.9 | Pfam-A | 25-62 (149) | alignment | ||
Range on Protein: 306-343
Range on HMM: 25-62/149.0
VVVVDWDRNSTKFHPSNSFSIPRWSGNDNDTTLFELTS
..|. | . |.| . |.. ||. || |. |.
eqildrrrrvvafapgavfafvRWaandfGtvvsrldi
|