Gene SSU72 in Homo sapiens

Synonym: HSPC182, PNAS-120, RP5-832C2.2, SSU72

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC2
Superfamily CC2
Family SSU72
Subfamily SSU72
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP113_AA protein Get Run
HsapP113_AA_2-194 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0053360 Phosphotyrosine protein phosphatases I 3-41 1.1e-06 19.3 In-house 3-49 (157) alignment 
Range on Protein: 3-41
Range on HMM: 3-49/157.0
SSPLRVAVVCSSNQNRSMEAHNILSKRG--------FSVRSFGTGTH
|....| .||  |  ||  |  .| ..         | |.| ||.. 
skmkkvLfvCtgNicRSpmAeallrhlleeaglgdrfevdSaGtsal
0046251 Phosphotyrosine protein phosphatases I 3-41 7.8e-06 16.7 In-house 3-50 (159) alignment 
Range on Protein: 3-41
Range on HMM: 3-50/159.0
SSPLRVAVVCSSNQNRSMEAHNILSKRG---------FSVRSFGTGTH
.....| .||  |  ||  |  .| ..          . | | ||...
lmkkkvlfvCtgNicRSpmAeallrhlledaglsdllievdSaGtsal
0042188 Phosphotyrosine protein phosphatases I 4-42 9.1e-06 16.4 In-house 3-45 (146) alignment 
Range on Protein: 4-42
Range on HMM: 3-45/146.0
SPLRVAVVCSSNQNRSMEAHNILSKRG---FSVRSFGTGT-HV
....| .||  |  ||  |  .| ..    . |.| ||.. ||
kkkkvlfvCtgNicRSpmAeallrhllgdrvevdSAGtsayhv
Ssu72 Ssu72-like protein 5-194 7.1e-91 292.3 Pfam-A 2-196 (196) alignment 
Range on Protein: 5-194
Range on HMM: 2-196/196.0
PLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDL
 |..||||.||||||||||..|...||.|.|||||..||||||. ||||||.|.|||...|.||..||.|||..||.|.||.||..|| .|||||..|. 
klklavvCasnqnRsmeaHkvlkeagfdvksfGtgsavklPGpsidkPnvyeFgttYeeiykdleskdeelYeenGllkmlernrkikkaPerfqeekea

--FDLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQ--HTEDMENEIDELLQEFEEKS-GRTFLHTVCFY
  ||...||||||.|.|||||..||.|. .||||.||||.||||||..||. |.||.....  ..||.|.|..|.|.|||||. ....|.||.||
gkfdvvitceervfdavvedllereselnrpvhvinvdikDnheealvgakailelvealeeeaeedleeeveeilaefeekepklkllytvafy
Ssu72 Ssu72-like protein 5-194 7.1e-91 292.3 In-house 2-196 (196) alignment 
Range on Protein: 5-194
Range on HMM: 2-196/196.0
PLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDL
 |..||||.||||||||||..|...||.|.|||||..||||||. ||||||.|.|||...|.||..||.|||..||.|.||.||..|| .|||||..|. 
klklavvCasnqnRsmeaHkvlkeagfdvksfGtgsavklPGpsidkPnvyeFgttYeeiykdleskdeelYeenGllkmlernrkikkaPerfqeekea

--FDLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQ--HTEDMENEIDELLQEFEEKS-GRTFLHTVCFY
  ||...||||||.|.|||||..||.|. .||||.||||.||||||..||. |.||.....  ..||.|.|..|.|.|||||. ....|.||.||
gkfdvvitceervfdavvedllereselnrpvhvinvdikDnheealvgakailelvealeeeaeedleeeveeilaefeekepklkllytvafy
subfamily_SSU72_pd Subfamily SSU72 6-194 3.7e-104 335.5 In-house 1-189 (189) alignment 
Range on Protein: 6-194
Range on HMM: 1-189/189.0
LRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDLF
||.|||||||||||.|||..|.|.||.|.|.|||..||||||. ||||||.|.|||...|.||..||||||||||.|.|||||.|||..|||||..|. |
lriavvcssnqnrsleahkllkkkGfnvksyGtgsavklPGpsidkPnvyefgttyediykdlkekdkelytqnGllemldrnrrikkaPerfqeekkkf

DLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQHTEDMENEIDELLQEFEEKSGRTFLHTVCFY
|..||.||||||.|||||.|||.....||||.||||.||.||||||||||.||.......||.|.||||.|.|||||. |..||...||
divltveervydavvedlesreeksskpvhvinvdikdnaeeatlGaflilelaeileksedledeideileefeektkrellhalafy
LMWPc_SSU72 6-177 6.9e-49 156.3 In-house 1-136 (137) alignment 
Range on Protein: 6-177
Range on HMM: 1-136/137.0
LRVAVVCSSNQNRSMEAHNILSKR--GFSVRSFGTGTHVklPGPAPDKPnvydfkttydqmyndllrkDKELYTQNGIlhmldrnkRIKPRPERFQNC-K
|.|..||.||.||||||...|...  |..|.|.|||..|  |||..|||                   ..|||..||.        .|| .||..|..  
lkvlfVCasNinRSmeAeallkealeglevkSaGtgslv..pgpsidkp...................aeelykenGl........sikeapeklqeeel

DLFDLILTCEERVYDQVVEDLNSReQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCiqhtedmenEIDELLQ
. |||..|.||||.|.|||||..| .|. ..|||.||||.|.||||. |.  |..|..          ...|||.
ekfDlvitleervfdavvedlper.selkrkvhvinvdikDpheeaiegfkaildliee.........rvkella
0048765 Phosphotyrosine protein phosphatases I 6-42 2.3e-06 18.3 In-house 3-48 (154) alignment 
Range on Protein: 6-42
Range on HMM: 3-48/154.0
LRVAVVCSSNQNRSMEAHNILSKRG--------FSVRSFGTGT-HV
 .| .||  |  ||  |  .| ..         . |.| ||.. ||
kkvLfvCtgNicRSpmAeallrhlleeaglgdrvevdSaGtsayhv
LMWPc_SSU72_ArsC 7-159 3.5e-36 114.9 In-house 2-126 (126) alignment 
Range on Protein: 7-159
Range on HMM: 2-126/126.0
RVAVVCSSNQNRSMEAHNILSKR---GFSVRSFGTGTHVklPGPAPDkpnvydfkttydqmyndllRKDKELYTQNGIlhmldrnkRIKPRPERFQNC-K
.|..||..|..||..|...|.|    |. |.|.|||..|  ||. .|                   ... ||...|||        ..| .|...|.   
kvlfvClgNicRSpmAeavlkkavkkglnvsSaGtgaav..pgksid...................sravellkengi........elkhkprqlqeedl

DLFDLILTCEERVYDQVVEDLNSReqeTCQPVHVVNVDIQDNHEEATLGAFLICELC
. ||||||..||..|.|.|.|..|   ....||..|.|..|..|.|. |.  ...|.
kefdliltmdernkdevlellper...atkkvhllnldvkDpyegaesgfeevldli