Gene EYA2 in Homo sapiens

Synonym: EAB1, RP5-890O15.2, EYA2

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family EYA
Subfamily EYA
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP115_AA protein Get Run
HsapP115_AA_266-537 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
EYA 267-537 1.6e-108 351.9 In-house 1-273 (274) alignment 
Range on Protein: 267-537
Range on HMM: 1-273/274.0
IERVFVWDLDETIIIFHSLLTGTFASRYG--KDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSsaPGANL
.|||.|||||||.|...|||.|..| ...  ||...|| ||...|..|..|||.|.|....|.||....|||..||.|.|||.|.|..|||..  .  .|
lervyvWdldetlillkslldGsyaekfdglkdhkksveigkrleklileladehffyeeieecdevflddvkedddGkdlsayefetdgfst..asddl

CLgsgvhggvdwmRKLAFRYRRVKEMYNTYknnVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKA---------------LNLINSRPNCVNVLVTTT
.            ||||.|||.||| |. .   ...|... |.|.. .||.|.. ||| ||. .||                | .|.|| |.||||||..
nk...........rklayryrkvkekyekg...leklldsekkealdelrseidkltdsWlssalklrlkkvcvreeadgkslleissrensvnvlvtsg

QLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGR-KAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEY
||||||||||||.|. ...|||.|||.| ||..||.|| .||.. |  .|||||| |||  ||....||..|. |.||.|. .||||..
qliPalakvllyrldeilaienvysaikvGklqcfkrikerfdkpkvrfvviGdGreeetaakalklPfvkielhpdlsarfpalelkt
subfamily_EYA_pd Subfamily EYA 269-538 5.6e-153 497.6 In-house 1-270 (270) alignment 
Range on Protein: 269-538
Range on HMM: 1-270/270.0
RVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGS
|||.||||||||||.|||||..|..|.||....|..||.|||.|||||||.|||||||..||.|||||||||||||||||||..||||..|..|||||..
rvfiWdldetiiifrslltgsyatkyakdansvvalglrmeelifnladtklffndleeidqvhvddvssddngqdlstynfatdgfhaaatsanlclai

GVHGGVDWMRKLAFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFP
||.||||.|||||||||.|||.||.||||||||.|. |||.|||||||.||||| |||..||.|.||.|| ||||||||||||.||||||||||||||||
gvrgGvdvmrklafryrkvkelynsyknnvggllgpakreawlqlraeiealtdsWltlalkslslissrsncvnvlvtttqlvpalakvllyglgsvfp

IENIYSATKTGKESCFERIMQRFGRKAVYVVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL
|||||||||.||||.||||..|||.|..||||||| .||..|||.|.||||||.|.||.||..||.||||
ieniysatkiGkesvferivsrfGkkvtyvvigdgkdeetaakklnlPfWrisshsdlaalysaldleyl