Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0045823 | Metallo-dependent phosphatases | 4-293 | 8.9e-123 | 403.3 | In-house | 27-328 (473) | alignment | ||
Range on Protein: 4-293
Range on HMM: 27-328/473.0
ISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVR
..|||. ||.|....|..|.... |. .|.||| .|.|..... ...|.||||||..||..|.. | ||....|.||.|||| .|.|...||||||..
lldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkik
YPDRITLIRGNHESRQITQVYGFYDECLRKYgSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT
||....|.|||||.|.....|||.||.|.|| .. ..... | ...| |.|.|.|||..|||||||....|||||.|.| .|.|.||...|||||||...
ypgnvfllrGNHElrllnglygfgdetleky.gedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdPwed
TG--------WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNET------VLTVWSAPNYCYRCGNVAAILELDEHLqKDFIIFEAA
| .| |||||||||| |.| .| |..|.|.|.|. |.|||...|. ..||.||||||.|.|| ||.|..||.| ||.|...
dgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdps
PQET
|..
phpl
|
|||||||||
subfamily_PPP4C_pd | Subfamily PPP4C | 5-292 | 7e-186 | 609.2 | In-house | 1-288 (288) | alignment | ||
Range on Protein: 5-292
Range on HMM: 1-288/288.0
SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRY
||||||||.|||||||||.|||||||||||||||||||||||||||||||||||||||.|||.||||||||||||.||||||||||||||||||||||||
sdldrqieklrrcelikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvry
PDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTT
||||||||||||||||||||||||||||||||..|||||||.||||||.||||||||||||||||||.|||.||.|||||||||.||.||||||||||..
pdritlirgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedae
GWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQE
||.|||||||||||||||.|||.||||..|||||||||||||.||||.|||||||||||||||||||||||||.|.||| |||||..|
gwavsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaaaae
|
|||||||||
subfamily_PPP2C_pd | Subfamily PPP2C | 5-292 | 8.2e-158 | 517.1 | In-house | 2-289 (290) | alignment | ||
Range on Protein: 5-292
Range on HMM: 2-289/290.0
SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRY
.|||..||.|..|. ..|||||.|| ||.||| .||||| | .|||||||.||||.|| |||..||..|.|||||.||.||||.||||| || ||||||
kdldklieklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvry
PDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTT
..|||..||||||||||||||||||||||||. .||.| |..||||.|.|..|..|||.||||||||.|||.||..|| |||||.||.||||||||.| .
keritilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpddrg
GWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQE
|||.||||||| || |. .|| .|.. .| ||||||||||.| ... | |..||||||||||| |||||||..|.. |. |..||..
gwgisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpaprr
|
|||||||||
0049330 | Metallo-dependent phosphatases | 5-293 | 3.7e-114 | 373.9 | In-house | 15-303 (309) | alignment | ||
Range on Protein: 5-293
Range on HMM: 15-303/309.0
SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRY
|.||..||.|... |..|.|.. |. ||.||| .|.|..... ...|.||||||..||..|.. | .||....|.||.|||| .|.|..|||||||..|
slldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalklly
PDRITLIRGNHESRQITQVYGFYDECLRKYGsVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPE-DT
||...|.|||||.|.....|||.||.||||| . .|..... ...| | |.|.|||.||||||||....||||| ..| .|.|.||..|||||||| ..
pdnvfllrGNHElrllnglygfgdetlrkyg.aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpir
TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQET
|.. .|||.|..|| ..| .| |..|.|.|.|..|..||...|.. ..||.||||||.|.||..|.||.||.| |..||..|...
egfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvplll
|
|||||||||
0053225 | Metallo-dependent phosphatases | 5-290 | 1.6e-110 | 362.0 | In-house | 7-292 (293) | alignment | ||
Range on Protein: 5-290
Range on HMM: 7-292/293.0
SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRY
..||..||.|... |..|.|.. |. .|.|||..|.|..... ...|.|||||...||..|.. | .||....|.||.|||| .|.|...||||||..|
llldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalklly
PDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTT
||...|.|||||.......|||.||.|||||. .|..... ...| |.|.|.|||..|||||||.. .||||| |.| ...|..|...||||||| . .
pdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlws
GWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAP
||. |.||.|..|| ..| .| .|..|.|.|.||.|..||...|.. ..||.|||||..|.||..|.|.|||.| .|..|.. .
gwlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapvl
|
|||||||||
subfamily_PPP6C_pd | Subfamily PPP6C | 6-294 | 2.4e-152 | 499.1 | In-house | 1-289 (290) | alignment | ||
Range on Protein: 6-294
Range on HMM: 1-289/290.0
DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYP
.||. ||. ..|. . |...|.||.. ..|.|||||| | ||||||||||||||||.|||| ||.||.|.|.|.|||||||.||.||| .||.||..||
eldkwielakkckylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakyp
DRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG
|||||.||||||||||||||||||||.|||....|.|||..|| |...||||....|||||||| ..||||||.|.| ||.||.|..|||.||||||
dritllrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpedvet
WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETR
| |||||||||||| |. .|.. |....||||||||.||.|..|.| . ||||||||||||||||.||.|... .... .|.| |.|.|
wavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklfkavpdeer
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 6-184 | 5.4e-38 | 123.7 | In-house | 19-203 (383) | alignment | ||
Range on Protein: 6-184
Range on HMM: 19-203/383.0
DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDS----PVTVCGDIHGQFYDLKELF-RVGGDVPETNYLFMGDFVDRGFYSVETFLLLLAL
.... ||.... .|.. | . .|...|.. |..|| . ||||||.||.. || .. . | .| .|.| ||||||| ||| |.||||
eveklieafkekkllhakyvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillillal
KVRYPDRITLIRGNHESRQITQVYGFYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSiQTLDQIRTIDRKQ
. || . | ||||| . ||| | || . . | ..| .| |...|| ||. ||||.| . |. . |.|..
llvypkevylnrGnhedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdk.tdlelldkiersk
|
|||||||||
subfamily_PPG1_pd | Subfamily PPG1 | 7-292 | 3.1e-137 | 449.8 | In-house | 1-299 (300) | alignment | ||
Range on Protein: 7-292
Range on HMM: 1-299/300.0
LDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPD
||. .|.|...||. |. ||.|. | .|.||.||||... ||||| ||.||||||. |.|..||.||.|||||.||.||||.||||| ||..||.|||
ldecleklqkaellpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklryps
RITLIRGNHESRQITQVYGFYDECLRKY-GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPE----
||||.|||||||||||||||| |||||| | .||.| |||||||.|.|||| .|.|||||||||....|||. .|| .|||..| ..||||||||
ritllrgnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennn
------DTTG--WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQE
| | . ||.||||| .| ||| .| ||.. | |||||..|||. .|.. . |||||||||||||| |.|||| |.... | ..|.||..
ptldhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvyeeapes
|
|||||||||
subfamily_Cele-PPP-Subfam4_pd | Subfamily Cele-PPP-Subfam4 | 9-289 | 3.2e-96 | 314.9 | In-house | 13-294 (298) | alignment | ||
Range on Protein: 9-289
Range on HMM: 13-294/298.0
RQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRI
... . .. |||..|. |...|..|. . . . ||.|..||||||||. || || .| |..||||.||.|||| ...|. .|||| ||.||...
vslsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnf
TLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPED-TTGWG
|.||||| .| .|||||.|| |.| |.... ..|. | | |.| |.|.|.|||||. ...|||.|.. | .. ... ||||.|||. ..||
fllrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpenavkgwa
VSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAA
. ||... ||.|||... |||...||||.| .||.. . ..|..|||.|| . | ||....||.|. | .. .
ensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpe
|
|||||||||
subfamily_PPP3C_pd | Subfamily PPP3C | 15-278 | 2.9e-86 | 283.0 | In-house | 36-312 (452) | alignment | ||
Range on Protein: 15-278
Range on HMM: 36-312/452.0
RRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGN
. ..|... . .| ..| .|... .|..|.||.|||||||||| .|| |||| .|.|||.||.|||| .|.|. | |.|||. ||... |.|||
lkegrleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGn
HESRQITQVYGFYDECLRKYgSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGV------
||.| .|. . | .|| || | .|. |.| || | |.|..... .|||||||| |..||.|...|| .|.|. ||.|||||||| . |
hecrhlteyftfkeeckiky.seevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfv
--SPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFN------ETVLTVWSAPNYCYRCGNVAAILELDEH
|.|| |... |..| .||. | |||. .||. . . ...|..|||||. | ||.|....
pnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyenn
|
|||||||||
subfamily_Cele-PPP-4C_pd | Subfamily Cele-PPP-4C | 15-289 | 1.6e-84 | 276.4 | In-house | 3-275 (280) | alignment | ||
Range on Protein: 15-289
Range on HMM: 3-275/280.0
RRCelIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGN
.| ||| ..... | ..||. .. . ||.||.||||.|||. || || . |..||||.||.|||| . .| ||||| |||||... ..|||
lac..ikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgn
HESRQITQVYGFYDECLRKYgSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPE-DTTGWGVSPRGA
|| .| . |||.||. |.| | .. |..| | | |.. |.|.|.|||||. ...||... . | . ... ||||.||| ..|||. ..||.
hevisinrkygfkdevkrry.slalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgv
GYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAA
..||..|| .. |||.|.| ||.| .||.. . ..||.|||.|. | ||.| .||.|. | .. |
svifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpa
|
|||||||||
subfamily_Cele-PPP-4D_pd | Subfamily Cele-PPP-4D | 15-287 | 7.6e-77 | 251.5 | In-house | 18-293 (297) | alignment | ||
Range on Protein: 15-287
Range on HMM: 18-293/297.0
RRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGN
...| | | | | ... . .. |..|. ||||||||| || ||. || | .||||.||.|||| .|.|| .|||| ||..| . |.|||
llskviteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgn
HESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSP---SIQTLDQIRTIDRKQEVpHDGPMCDLLWSDPED-TTGWGVSP
|| . .|||||.|| ..| || .. ..|..| |. .| ||.|.|||||| ||| .| |.| .| ... ..||||.|| .|.
hecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenq
RGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFE
|||| || | | . . ..|..|||||.| .||.. ..|..||| || . |.||.. ||.|| | |.
rgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilr
|
|||||||||
subfamily_Cele-PPP-4B_pd | Subfamily Cele-PPP-4B | 17-293 | 7.3e-86 | 281.1 | In-house | 21-298 (299) | alignment | ||
Range on Protein: 17-293
Range on HMM: 21-298/299.0
CELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHE
. .|| |.. ||| |........ . |..|. ||||||||. || .| . | |..|.||.||.|||| .|. |||. |..||.|. ..|||||
tksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhe
SRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT-TGWGVSPRGAGY
| .|||||.|| ..| | .| . |... |. .| ..|.|.|||||| .|||||.| . | |. | ||||.||... .| || |
cpainrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsvkdwlanvrgvsy
LFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQET
.|| ||||. |||...||||.| .||.. . ..|..||| || . | |||...|| | | ... .|..
vfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpksl
|
|||||||||
subfamily_Cele-PPP-2B_pd | Subfamily Cele-PPP-2B | 17-284 | 1.5e-73 | 240.7 | In-house | 3-270 (280) | alignment | ||
Range on Protein: 17-284
Range on HMM: 3-270/280.0
CELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHE
|... |. |. |..||||. ..|. | |||| |. |.. || . | ||| . .|.||.|||| .| ..||..||.|| ||| |.|||||
cnvmtgheiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhe
SRQITQVYGFYDECLRKYGsVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPED-TTGWGVSPRGAGY
. . ..|||| || ||| | .| .|. . .|..| ...|.|||||| . || || | | | | . ||||||| . || | || |
tpsvnkiygfyvecqykyg.vglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisy
LFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFI
.|| || | . .||.| ||||.| .||. ..||.| |||| . | ||.. |. || |
mfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfq
|
|||||||||
subfamily_Cele-PPP-1A_pd | Subfamily Cele-PPP-1A | 18-287 | 7.1e-83 | 271.3 | In-house | 6-281 (284) | alignment | ||
Range on Protein: 18-287
Range on HMM: 6-281/284.0
ELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDV------PETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLI
.|.|| |. || .|||.. .|. . ...||...||||||| ||. |. . | |..|||.||.|||| .|.| .||.|.|...||...|.
kllkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvfll
RGNHESRQITQVYGFYDECLRKYgSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT-TGWGVSP
||||||| . . |||| || ..| |.... | . |.|... ||.|.|||.| . |.|. ..| ..| | ..|| |.||| . .|. ||
rgnhesrpvnmqygfyleckkry.sealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegykesp
RGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFE
|||| .||.. | .|. ..|.. ||||.||.||.. . ..|..||| || . |.||.|..||.| | ...
rgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlk
|
|||||||||
subfamily_Cele-PPP-3B_pd | Subfamily Cele-PPP-3B | 18-286 | 3.6e-64 | 209.5 | In-house | 14-286 (290) | alignment | ||
Range on Protein: 18-286
Range on HMM: 14-286/290.0
ELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHES
. ...... . |..||| . .| .|... ||||||. .| . | | |. ..||.||.|||| |.| |||. .|.||. .. |.|||||
dafsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhllrgnhev
RQITQVYGFYDECLRKYGSvTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQ--EVPHDGPMCDLLWSDPED---TTGWGVSPRG
|.. ..|||..| || || .|. ..|. ||| | .. ||.|.|||.|. |.. . .... . . ..| . ||||.||. | |.
rkvnrlygfkeelarkrgs.rlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddtialnkqra
AGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIF
.|| ... .. ...| |||.. ||... |.. ..||.||| |. . |. ||... | |. ....
isvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvl
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 18-70 | 1.2e-13 | 44.0 | In-house | 7-59 (317) | alignment | ||
Range on Protein: 18-70
Range on HMM: 7-59/317.0
ELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGG
.|.||.|. || .|||.. .| ....|||..||||||| ||. |. . |
dlfkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 18-68 | 1.4e-08 | 27.2 | In-house | 9-59 (339) | alignment | ||
Range on Protein: 18-68
Range on HMM: 9-59/339.0
ELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRV
.|. .|. || .|||.. | . ....|. | ||||||| || .. .
dlfcaaelaelchrareliwsepiflkleapicvmgdihgqfddllamldm
|
|||||||||
subfamily_PPP1C_pd | Subfamily PPP1C | 19-288 | 6.4e-108 | 353.2 | In-house | 9-278 (282) | alignment | ||
Range on Protein: 19-288
Range on HMM: 9-278/282.0
LIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESR
.||.|..||..||||||.... . ... ||...||||||..|| || .| ||.||||.||.|||| |.|| .||||.|..||... |.||||||
klkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesa
QITQVYGFYDECLRKYGSVtVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPED-TTGWGVSPRGAGYLF
.|...||||||| |.|.. .|. |..|..| |.|..| ||.||||||||... |.|||.| | |||..| .||||||||.. ..||. . || . |
sinriyGfydeckrrysik.lWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsftf
GSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEA
|.|||..| . ||.|.|.||||.| .||... .. ..||.|||||| . .| .|.|..||.| .| |. .
gkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkp
|
|||||||||
subfamily_PPZ_pd | Subfamily PPZ | 19-285 | 2.9e-78 | 256.4 | In-house | 24-290 (300) | alignment | ||
Range on Protein: 19-285
Range on HMM: 24-290/300.0
LIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESR
.|.||. .| ||||... . .. . .| . ||.|||. || || | | .||||.||.|||| |.|| ||||. |..||. . |.|||||
clknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnheca
QITQVYGFYDECLRKyGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTT-GWGVSPRGAGYLF
..|.|||||||| |. . .|. . |. | |.||. |||||||||||| ....|.|| . | .|| | . ||||||| |.. | || | .
nvtrvygfydeckrr.cnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewednergvsycy
GSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFII
. .| .|..|||| .| .||.. . ...||.|||||| | |.. . | | | .
nkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfel
|
|||||||||
subfamily_Cele-PPP-Subfam3_pd | Subfamily Cele-PPP-Subfam3 | 19-287 | 2.2e-72 | 236.4 | In-house | 9-280 (287) | alignment | ||
Range on Protein: 19-287
Range on HMM: 9-280/287.0
LIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESR
...... . |..||| . . .|..|.|..||||||. || .| | |...|||.||.|||| |.| |||..||..|| .. |.||||| .
afsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllrGnhevk
QITQVYGFYDECLRKYGsVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE--VPHDGPMCDLLWSDPED-TTGWGV-SPRGAG
.| ..|||..| ||.. ... ..|..|.| |... .|.|.|||.|| ...||..... . . ..| . ||||.||| . . . |.
kinklyGfkeelkrkrq.erlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfelnkirais
YLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFE
.|| .| .. |||.| |||... |||.. |.. ..||.||| |. . |..|.. ... |. |. .
vvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlk
|
|||||||||
subfamily_Cele-PPP-4A_pd | Subfamily Cele-PPP-4A | 19-287 | 1.1e-70 | 231.3 | In-house | 2-272 (284) | alignment | ||
Range on Protein: 19-287
Range on HMM: 2-272/284.0
LIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESR
|| .|..| .| .|. .. . |.||. .|||||||| || || | .||||.||.|||| . .|| |||.| || .|... ..|||||
lippedvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecs
QITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPM-CDLLWSDPED-TTGWGVSPRGAGYL
| ..||||.|| |.| .|. .| . |.|.. .|.|.|||.| .| . |.|.| | . | . |.||||| . || || |.
linkiygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyv
FGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFE
|||| . .. .||.. ||||.| .||.. | ..|..||| || . | ||.. ... | |...
fgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvlr
|
|||||||||
PPP_3 | 20-287 | 4.8e-122 | 399.2 | In-house | 2-270 (271) | alignment | |||
Range on Protein: 20-287
Range on HMM: 2-270/271.0
IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ
..|.|.| |. |..||| .|||......|||||||||||..|| |||..||..|||.|||.||.|||| .|.|..|||||||..||....|.||||||||
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq
ITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDL-LWSDPEDTTGWGVSPRGAGYLFG
|..||||..|.|.|.|. .|.....|.|..|.|.|.||.|...|||||||||..||||....||.|||..|...|| |.||||...|.. |.||||.|||
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFg
SDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFE
.||...|. .|....|.|||.|..|||. .... |.||.||||||.|..|..|||.|.|.|...| ..|
pdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkqle
|
|||||||||
subfamily_Cele-PPP-5_pd | Subfamily Cele-PPP-5 | 20-279 | 4.4e-52 | 170.1 | In-house | 6-290 (302) | alignment | ||
Range on Protein: 20-279
Range on HMM: 6-290/302.0
IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVG--GD---------VPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRI
..||. .|. . | | .|... .. .|||. ||||||| || .. . . ..|.||.|||| |.| |..|||| || .
ysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptny
TLIRGNHESRQITQVYGFYDECLRKYGSVT---VWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRK-QEVPHDGPMCDLLWSDPEDTT
|.|||||.. | ||| .| ..| .|. |.| .. |.|.. ||.|||||.|| ...|..|. |.| .|| .| |||..|| |.
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvq
GWGVSP----------RGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHL
. . . || ..| | .. ....| |||| . ||.|.. .. .||..|||.| | |.|..|
llaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtng
|
|||||||||
subfamily_Cele-PPP-Subfam5_pd | Subfamily Cele-PPP-Subfam5 | 20-279 | 5.7e-52 | 169.8 | In-house | 7-291 (302) | alignment | ||
Range on Protein: 20-279
Range on HMM: 7-291/302.0
IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVG--GD---------VPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRI
..||. .|. . | | .|... .. .|||. ||||||| || .. . . ..|.||.|||| |.| |..|||| || .
ysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptny
TLIRGNHESRQITQVYGFYDECLRKYGSVT---VWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRK-QEVPHDGPMCDLLWSDPEDTT
|.|||||.. | ||| .| ..| .|. |.| .. |.|.. ||.|||||.|| ...|..|. |.| .|| .| |||..|| |.
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvq
GWGVSP----------RGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHL
. . . || ..| | .. ....| |||| . ||.|.. .. .||..|||.| | |.|..|
llaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtng
|
|||||||||
PPP_1 | 21-274 | 2e-115 | 377.6 | In-house | 2-263 (264) | alignment | |||
Range on Protein: 21-274
Range on HMM: 2-263/264.0
KESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI
.|.|...|. |..|.|..|.|...|....||||||||||.|| .||.|||..|||||||.||.|||| .|||..|||||||..||....|.||||||||.
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqv
TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDL--------LWSDPEDTTGWGVSPRG
|.||||..|.|.|..| ......|..||.|.|.|.||.||..|||||||....|||||...||.|||..|..||| |..|.|..... |.||
tkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRG
AGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILE
||||||.||...|. .|....|.|||....|||.......|.|..||.||.....| .|...
agylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk
|
|||||||||
PP2Ac_SM00156 | 21-288 | 1.5e-106 | 348.3 | In-house | 2-269 (271) | alignment | |||
Range on Protein: 21-288
Range on HMM: 2-269/271.0
KESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI
...||..|. ...||| .|.|. .|..||||.||||||..|| .|.. .| .||..|.|.||.|||| .|.|. |||.|||..||....| ||||||...
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssv
TQVYGFYDECLRKYgSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDP-EDTTGWGVSPRGAGYLFGS
...|||..|. ||| . .. ..|.|..|.|.|..| ||.|.||||||....||.|| ..| .| |..|...||||||| ... |. | ||....||.
nkiygfeeevkrky.gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFge
DVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEA
|.| .| .|....|.|||..|.|||.. ... ..|..||||||....|.||.|.....|. .. ...
davkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlke
|
|||||||||
subfamily_Cele-PPP-Subfam2_pd | Subfamily Cele-PPP-Subfam2 | 21-289 | 1.1e-81 | 267.2 | In-house | 9-277 (281) | alignment | ||
Range on Protein: 21-289
Range on HMM: 9-277/281.0
KESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI
. |.... ... |..||... .|.|..| ||.|.|| |||.|| . | |||. ..|.||.|||| |.|...||..||.||.||| |.||||| ..
tkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnheiasv
TQVYGFYDECLRKYGsVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPED-TTGWGVSPRGAGYLFGS
..|||| || ||| . .| . |. | .|| |. .. |.|||||| . .||..| . . . .. | . ||||.||.. . .| | ||....||
nkiygfyvecvtkyG.eelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssftfGk
DVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAA
.|| . ....| ||||.|..||. ..||.|.|||| | ||.| .|| |. ... . |
nvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislvalvpa
|
|||||||||
subfamily_Cele-PPP-2A_pd | Subfamily Cele-PPP-2A | 23-291 | 4e-63 | 206.4 | In-house | 23-294 (307) | alignment | ||
Range on Protein: 23-291
Range on HMM: 23-294/307.0
SEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQ
|.. . .|. |. | . .| |. | ||.|||| || ..| . | ||| |.| ||.||||. |.|. |||.. |. ||. | |.||||| .. .
eefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnk
VYGFYDECLRKYGS--VTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT-TGWGVSPRGAGYLFGS
||||.||. .| |. | .||.| ||.|.||||||.. ||..| . | | . |.||.||. . | | ||.|. ||.
kygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftfgt
DVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQ
.|. . ...| ||||....|| ..|..||| || | ..| .|| | . . | . .
nviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlvafvpese
|
|||||||||
subfamily_PPP5C_pd | Subfamily PPP5C | 25-290 | 3.3e-83 | 272.4 | In-house | 39-310 (322) | alignment | ||
Range on Protein: 25-290
Range on HMM: 39-310/322.0
VKALCAKAREILVEESNVQRVD----SPVTVCGDIHGQFYDLKELFRVGGDVPET-NYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ
. .. ..|.|.| ... . .. . .||||||||||||| ..|.. | . |. ||| ||||||| .|||. |.||..|. ||... | |||||| .
alkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfkllyPnhfflsrGnhesdn
ITQVYGFYDECLRKYGSvTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSP-SIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFG
. ..||| .|. || . .| ||.|..| |. .|. |.. ||||| |||..|.||| .. |..| ...||||||....| . | || | ||
mnklyGfegevkakyte.kvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqeanGrspskrGvgvqfG
SDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILEL-DEHLQKDFIIFEAAP
|| .| |....| |.|.. .|||. . . ..||.|||||| . || .|...| ...|. | ||| .
pdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfeave
|
|||||||||
subfamily_PPPLV_pd | Subfamily PPPLV | 26-277 | 1.6e-54 | 178.2 | In-house | 3-277 (290) | alignment | ||
Range on Protein: 26-277
Range on HMM: 3-277/290.0
KALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDL----KELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQIT
.|| .| .||..| .. ..||. | ||.||.. || | |.|.| |. ...||.||.|||| .||| |||||| || .. |.||||| . ..
lslcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvq
QVYGFYDECLRKYGSV--TVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDR---KQEVPHDG-PM-CDLLWSDPEDTT----------
. . .. |. |.| || ...||.| |.|.|| |.||||.|. .|.| .| .|. . . . || |. |.|||||..
esieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvl
--GWG-VSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCgNVAAILELDE
|. . || |..|..| . .| |... . |||. .|.. . .|||.|. .|| | ||.. .|.
neGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGss.neaalilvdk
|
|||||||||
subfamily_Cele-PPP-3A_pd | Subfamily Cele-PPP-3A | 45-287 | 1.7e-55 | 181.6 | In-house | 5-254 (263) | alignment | ||
Range on Protein: 45-287
Range on HMM: 5-254/263.0
VDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSV----TVW
...|. .||| |||. || .| | .|.|||.||.|||| .|.| .||..||. | .. |.||||| . | . |||. | ... .|.
lqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevyesvy
RYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPM-CDLLWSDPE-DTTGWGVS-PRGAGYLFGSDVVAQFNAANDIDMICRA
. ..| |. | ||. .|.|.|||.|| ...||.||.| | . |. |||||.||| |. |. | .|| | .. |||.| ||
nhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidlivra
HQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFE
||.| || . . ..||.|| | | ||.. ... |. |. ..
hqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlk
|
|||||||||
Metallophos | Calcineurin-like phosphoesterase | 48-240 | 3e-47 | 154.5 | Pfam-A | 2-198 (200) | alignment | ||
Range on Protein: 48-240
Range on HMM: 2-198/200.0
PVTVCGDIHGQFYDL----KELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLL--LALKVRYPDRITLIRGNHESRQITQVYGFYDECL----------
...|.||.||...|| .|...... . ...||.||.|||| .| ||. || |.||...|... |.||||||......|||..|.|
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange
-----------------------RKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIrtidrkqevphdgpmcdllwsdpedttgwgv
.... ..... |.|..|.| |..||||...||.||.| .. |.|
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................
sprgAGYLFGSDVVAQFNAANDIDMICRAHQL
...|||.|.. . ...|...|.|.
....gselfgpdalekllekygvdlvlrGHtH
|
|||||||||
PPP_2 | 49-240 | 9.1e-83 | 269.8 | In-house | 1-197 (198) | alignment | |||
Range on Protein: 49-240
Range on HMM: 1-197/198.0
VTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFD
||||||.|||..|| .||..|...||..|||.||.|||| .|.|..|||||||..||....|.||||||.....||||..|.|.|.|. .|.....|.|.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe
YLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDL-----LWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL
.|.|.|.||.|...||||||..|..||||....||.|.|..|...|| |....|..... | ||||.|||.||.... .|....|.|||..
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
|
|||||||||
PPP_4 | 49-240 | 5.8e-78 | 254.5 | In-house | 1-196 (197) | alignment | |||
Range on Protein: 49-240
Range on HMM: 1-196/197.0
VTVCGDIHGQFYDL-KELFRVGGDVP-ETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKyGSVTVWRYCTEI
|||.||||||..|| .|...||. . |..|.|.||.|||| .|.|..|||||||..||....|.||||||......|||..|.|.| . .........
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.hgkeilkklqdv
FDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVP-HDGPMCDL-LWSDPE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL
||.|.|.|.||.|...||||||.....||.|..|.||.|.| ... ..|| |||||. ...|. | ||||.|||.||. .| .|....|.|.|.|
fdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
|
|||||||||
PPP_5_Dcr2 | 49-240 | 1.5e-76 | 249.8 | In-house | 1-198 (199) | alignment | |||
Range on Protein: 49-240
Range on HMM: 1-198/199.0
VTVCGDIHGQFYDL-KELFRVGGDVP-ETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEI
||||||.|||..|| .||. ||| . |..|.|.||.|||| .|.|..|||||||..||....|.|||||..|....|||..|.|.||.. ........
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv
FDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVP-HDGPMCDL-LWSDPE-DTTG-WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL
||.|.|.|.||.|...|||||||.|....... |.||.|.| ..| ..|| |||||. ...| . | ||||.||| ||. .| |....|.|.|.|
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshel
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 75-287 | 2e-70 | 230.5 | In-house | 101-313 (317) | alignment | ||
Range on Protein: 75-287
Range on HMM: 101-313/317.0
TNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYgSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTL
.|||.||.|||| .|.| .||.|||..|||...|.||||||| . . |||| |. ..| |.... .| | |.|... ||.|.|||.| .. |
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkry.saalyeafqlafnvlplcavvnkkilcmhGGiseelldl
DQIRTIDRKQEVPHDGPMCDLLWSDPEDT-TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAIL
.|. ...| ..| | ..|| |.||. . .|. |.|||| .||.. | .|. |.|.. ||||.|..||.. . ..|..|||.|| . |.||.|
kqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavl
ELDEHLQKDFIIFE
..|..|. . ...
svdkklkisinvlr
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 76-287 | 2e-54 | 177.9 | In-house | 121-332 (339) | alignment | ||
Range on Protein: 76-287
Range on HMM: 121-332/339.0
NYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSvTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLD
|||.||.|||| .|.| .|| |||. ||||| |.||||||| . |||| | .| . .. ..|. . . |.|. |.|.|||.| . ...
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyryda.qlyecfqnmfnvfpfcavinntimcmhggisehltsfn
QIRTIDRKQEVPHDGPMCDLLWSDPEDT-TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILE
|. . | |.| | . || |.||. | |. | ||| ..|| . | |..|. | ||.| .||.. ..|..|||||| . | ||..
qfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfs
LDEHLQKDFIIFE
.|..|. .|
idkklkisinvfr
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 192-294 | 1.2e-19 | 63.3 | In-house | 237-339 (383) | alignment | ||
Range on Protein: 192-294
Range on HMM: 237-339/383.0
MCDLLWSDPEDTTG-WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAp
. |.|||||. ..| . . ||.| ||.|| ... . ..... |.|. .|||.. ...|||..|| || | | . | ..|. .. . |.
vldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltprivqyqas.
QETR
..|.
katk
|