Gene PPIP5K2 in Homo sapiens

Synonym: HISPPD1, IP7K2, VIP2, PPIP5K2

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily PPIP5K
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP165_AA protein Get Run
HsapP165_AA_328-942 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
RimK RimK-like ATP-grasp domain 235-333 1.8e-07 20.2 Pfam-A 79-176 (190) alignment 
Range on Protein: 235-333
Range on HMM: 79-176/190.0
IYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPalDGKVERDSEGKEVRYPVILNAREKLIAWKVCLAFKQTVCGFDLLRANGQSYVCDVNGFSFVKNSMK
.  ||. . . .|..|. || .   |  |.|   .|      .   |  .. |.  |. .| |.  |....|.| |.|...   .|..||    .|.. |
lvQefIeeaenrdiRvlVvgdevvaalervsk..eGdfrsNlarGgvaeklqlseeeeelaikaaeameldvlgvDileskrgllvlEvNssvglkkiek
0049059 Phosphoglycerate mutase-like 329-919 1.1e-63 208.7 In-house 2-409 (435) alignment 
Range on Protein: 329-919
Range on HMM: 2-409/435.0
KNSMKYYDDCAKILgnIVMRELAPQFHIPWSIPLEAeDIPivpttsgTMMELRCVIAVIRHGDRTPKQKM--KMEVRHQKFFDLFEKCDgyksgklklkk
|  ...|.|...||  ...  |.| |..|.. ...  |.|       . .||..|....|||.|||..|.  |.|. ..|...|. ...           
ktlapvysdgfnil..lllgtlspyfsapgvfgisl.dvp.......egcelkqvqvlfRHGaRtPtsklikklealwekllslltypn...........

pkqlqevldiarqllmelgqnndseieenkpkleqlktvlemyghfsginrkvqltylphgcpktsseeeDSRREEPSLLLVLKWgGELTPAGRVQAEEL
                                                                      ..  . ..  ..|.. ||||| ||.|| ||
......................................................................gplsflndwnyplga.geLTplGreqayel

GRAFRCMYpggqgdyAGFpgcgllrlhstYRHD-LKIYASDEGRVQMTAAAFAKGLLALEgeltpilvqmvksanmnglldsdsdslsscqqrvkarlhe
|. .| .|        ..           |..| .....||..|....|.||..||.  |                                        
GkrlrkrY.......gfL...........ynpdevyvrssdvdRtlqSaqaflaGlfppe........................................

ilqkdrdftaedyekltpSGSISLIKSMHLIKNPVKTCdkVYSLIQSLTSQIRHRMEDPKSSDIQlyHSETLELMLRRWSKLEKDFKTKNGrYDISKIPD
                  . ...|..... .  ..     | |.. .|.......... ......   .|.|||.|.|..|| ...  . | ...|...|
..................ilgsqllnplnvyqpvpiet..vdsdndtlpydscpafdellkella..sdeflelflerilkllqellpglg.ltpsdvld

IYDCIKYDVQHNGS-----LKLEN--TMELYRLSKALADIVIPQEYGITKaeklEIAKGYCTPLVRKIRSDLQRTQDDDTVNkLHPVYSRGVLSPERHVR
.||..|||....|.     |.. .  |.|...  ..|||......||..     |||| ...||...| ..|......|..| |.. ........ ....
lydlckydtlllgyahglplpfcslfteeelevleyladlefyylygygd....eiaklaggpllneilarledaingdstn.lnltldsnpatfpldlk

TRLYFTSESHVHSLLSILRYgalcnTNDSQNedggmvkemESKDEQWKRAMDYLNVVNELN-YMTQIVIMLYEDpnkdlSSEERFHVELHFSPGA---KG
 .|||........|||.| .     ..| .           ..|.......|.| ...|.. |....|. |||.     .......|.....      .|
lylyfaHdttiapllsaLgl.....fddqlp.........lpadntpfpeldrlfrtseivPyasnlvfElyec.....pdgneyyVrvlyngkvlplpg

CEEDK
|....
cgsgp
0047369 Phosphoglycerate mutase-like 340-919 9.3e-61 199.3 In-house 3-411 (438) alignment 
Range on Protein: 340-919
Range on HMM: 3-411/438.0
KILGNIVMRELAPQFHIPWSIPL-EAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPkQKMKMEvRHQKFFDLFEKCDGYKSgklklkkpkqlqevldiar
|||............|. . .|  .| ........  . .||..|....|||.||| .|.|.. .......|.|.  .|.|                   
kilapvlsvdfnillhlgtlspyfsapgvglisldvpegcelkqvqvlfRHGaRtP.tksklk.kleplwellenattyps...................

qllmelgqnndseieenkpkleqlktvlemyghfsginrkvqltylphgcpktsseeeDSRREEPSLLLVLKWgGELTPAGRVQAEELGRAFRCMYpggq
                                                          ..    ...| .... |.||| ||.|| |||. .| .|    
..........................................................gplsflndwlgpcga.gqLTplGreqayelGkrlrkrY....

gdyagfpgcGLLrlhstYRHDL-KIYASDEGRVQMTAAAFAKGLL--ALEGELTPILVQmvksanmnglldsdsdslsscqqrvkarlheilqkdrdfta
         |||     ...|. ....||..|....|.||..||.   ..|||.|||.|                                         
.........glL.....npedvlyvrssdvdRtlqSAqaflaGlfppegtgelapilwq.........................................

edyekltpsgsisliksmhliKNPVKTCDKVYS-LIQSLTSQIRHRMEDPKSSDIQLyhSETLELMLRRWSKLEKDFKTKnGRYDISKIPDIYDCIKYDV
                       |. |  . .. |  .| |.  ..... .......  .|.|||.|....|. |..      ...|...|.||...|| 
.....................pipihtipesddfllnllpsdscpafdellkeflas..deflelllkdilkrlkkllpg.lnltpsdvldlydlcaydt

QHNGS-----LKLEN--TMELYRLSKALADIVIPQEYGITKaeklEIAKGYCTPLVRKIRSDLQRTQDDDTVNKLHPVYSRGVLSPeRHVRTRLYFTSES
..||.     ... .  |.|...  ..|||.. ...||...    |.|| ...||...| ..|.........|  ....|.||..| .... .|||....
langyaglplspfcslftpeelevleyladlefyylygygn....elaklaggpllneilarledaingkstnlnltldsngvtfP.ldlklylyfaHdt

HVHSLLSILRYgalcnTNDSQNEDggmvkemesKDEQWKRAMDYLNVVNELN-YMTQIVIMLYEDPnkdlsSEERFHVELHFSPGA---KGCEEDK
....|||.| .     ..| .  .         .....| |...| ...|.. |....|. |||.|     |.....|......     .||....
tiaallsaLgl.....fddtwplp.........glpldkialnrlfrsseivPyasnlvfElyecp.....sdgeyyVrvlyngkvlplpgcgsgp
0048946 Phosphoglycerate mutase-like 341-919 6.6e-59 192.9 In-house 2-385 (447) alignment 
Range on Protein: 341-919
Range on HMM: 2-385/447.0
ILGNIVMRELAPQFHIPWSIPLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVrhQKFFDLFEKCdgyksgklklkkpkqlqevldiarql
.||....... ...|. ...| .. . . .|..  . .||..|....|||.|||..|.....  ....||...                           
llgpaladgfnillhlgtlspyfsvpgygipepvpegcelkqvqvlfRHGaRtPtkkylkgl..eplldllkna..........................

lmelgqnndseieenkpkleqlkTVLEMYGHFSGINR-KVQLTYLPHGCpktsseeedsrreepslllvLKWgGELTPAGRVQAEELGRAFRCMYpggqg
                       .|||..|..|..|. |.||.. |..                     ... |.||| || |. |||...| .|     
.......................nvlelggdlsflndwkyqlkneplwp....................cgl.gqLTplGreqlyelGkrlrkrY.....

dyagfpgCGLLRlhstYRHDLKIYASDEGRVQMTAAAFAKGLLALEG--ELTPILVQMVKSANMNGLLDsdsdslsSCQQRVkarlheilqkdrdftaed
        |||.    .........||..|....|.||..||.  |.  . .|| ...|.| | | ||.       ||. ..                  
.......lgllp....npseiyvrssdvdRtlqSaqaflaGlfppepplgyqpipihtvpssndnlllp.......sCpafk..................

yekltpsgsisliksmhliknpvktcdkvysliqsltsqirhrmedpksSDIQLYHSETLELMLRR-WSKLEKDFKTKNgrYDISKIPDIYDCIKYDVQH
                                                 .... ...| |. .|.. ...|.| ... |  ...|.. |.||...|. ..
.................................................ellkkelaeelkellkellerlkkllggln..ltlsdvydlydlllyetai

NGSLKLEN--TMELYRLSKALADIVIPQEYGITKaeklEIAKGYCTPLVRKIRSDLQRTQDDDTvnklhpvysrgvlsperhvRTRLYFTSESHVHSLLS
.|. .| .  |.|...  ..|||.. ..|||..     |.|. ...||...| ..|......|.                   . .|||........|||
hglsplcslftpeelevleyladlefyyeygygd....elarlaggpllneilarledaisgds...................klylyfaHdttiaalls

ILRYgalcnTNDsqnedggmvkemeskdeQWKRAMDYLNV-----VNELN-YMTQIVIMLYEDPNKdLSSEERFHVELHFSPGA---KGCEEDK
.| .     ..|                 .. . .|.|..     ..|.. |....|. |||.|.. |.|.... |......     .||. ..
aLgl.....fdd.................elplpadnlpfnrlfrsseivPyasnlvfElyecpss.lpsdgeyyVrvlyngeplplpgCgsgp
subfamily_PPIP5K_pd Subfamily PPIP5K 355-916 3.6e-292 959.4 In-house 4-550 (551) alignment 
Range on Protein: 355-916
Range on HMM: 4-550/551.0
HIPWSIPLEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEKCDGYKSGKLKLKKPKQLQEVLDIARQLLMELGQNNDSEIEE
.|.....||.||.||||||||..||||||||||||||||||||.||||.|.||..||||.||||....||||||||||||||.|.||.|. .....||||
eikkklalekedlPivpttsgkkmelrcviaviRHgDRtPkqklkmevthpkflelfekydgykkkevklkkpkqLqevLdivralleekekkseeeiee

NKPKLEQLKTVLEMYGHFSGINRKVQLTYLPHGCPKTSSEEEDSRREEPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHS
.| ||.|||.|||.|||||||||||||.||.... |||||||.|.|||.||||.|||||||||||.||||||||||||.||||.|||||.||.|||||||
eksklkqlknvLekyghfsGinrkvqlkylkkrtektsseeeeskreeeslllilkWGGEltpagkvqAeelGrafRclyPggdgdyaglpGlgllrLhs

TYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSlSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMH
||||||||||||||||||||||||||||||||||||||||.|||||.|.|||.|.|. ...|.|||..|||.||.|..||.||.|||.|..| ||.|...
tyrhdlkiyasdEgRvqmtAaafakgllaleGeltpilvqlvksanvndlLDddkda.kklqdrvkkklhellqedkeftpedieklaPeksksllkalk

LIKNPVKTCDKVYSLIQSLTSQIRHRMEDPKSSDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDISKIPDIYDCIKYDVQHNGSLKLENTMELYRLSKA
 ||||||...||..|...|......|.|..||.|..|||||||||. |||.||||.||.|....||||||||||.||||.|||.||.||.|.|||.|.||
kiknPvkvikkvvelveelvkilkdriekkkskdlrlyhsetleLlkrRWeklekeFkekekkfdiskipdiyDsikYdlqHnkslgleqtselyklaka

LADIVIPQEYGITKAEKLEIAKGYCTPLVRKIRSDLQRTQ-DDDTVNKLHPVYSRGVLSPERHVRTRLYFTSESHVHSLLSILRYGALCNtndsqnedgg
||||||||||||||.|||||.|..|.||.||||.||.||. .|.|.|.|.| .|.||||||||||||||||||||.||||..||||.|..          
ladiviPqEYGitkeekleigkaiclpLlrkirnDlkrtekedetknrlepalskgvlsPerhvrtrlYFtsEsHihsllnvlrygglld..........

mvkemESKDEQWKRAMDYLNVVNELNYMTQIVIMLYEDPNKDLSSEERFHVELHFSPGAKGCE
     |.||||||||.|||. ..||||.||||.|||||..|| ||||||.|||.||||.|..|
.....evkdeqwkraldylsaleElnYltqivlmlyEdkskdasseerfsvelkfspGvktqe
0048439 Phosphoglycerate mutase-like 375-917 1.4e-51 169.0 In-house 6-348 (391) alignment 
Range on Protein: 375-917
Range on HMM: 6-348/391.0
GtmMELRCVIAVIRHGDRTPKQKMKM--EVRHQKffdlfekcdgyksgklklkkpkqlqevldiarqllmelgqnndseieenkpkleqlktvlemyghf
|  .||..|....|||.|||......  .  ..|                                                                  
g..celkqvqvlfRHGaRtPtssypnkldpllnk..................................................................

sginrkvqltylphgcpktsseeedsrreepsLLLVLKWG-GELTPAGRVQAEELGRAFRCMYpggqgdyagfPGCGLLRLHSTY-RHDLKIYASDEGRV
                                ||.. ..| ||||| || |. ||||..| .|          .  |||. ..|. ........||..|.
................................llpngpcglgeLTplGreqlyelGrrlrkrY..........vdlgllpskytlnpsevyvrssdvdRt

QMTAAAFAKGLLAlEGELTPILVQMVKSANmNGLLDSDSDSLSSCQqrVKARLHEILQKDRDFTAEDYEKLTPSGS--ISLIKSMhliknpvktcdkvys
...|.||..||.  ...||.|||..|.|.. ..| . . .. . ..  ....|  . . .| .. | .|.| .  .   .|....               
lqSAqaflaGlfp.plgltvilvivvesed.pllnplpintcplle..dlllldalsalprfylseilerlaevlnrvlglnlta...............

liqsltsqirhrmedpkssdiqlyhsETLELMLRRWSKLEKDFKTKNGR-YDISKIPDIYDCIKYDVQHNGSLKLENTMELYRL--SKALADIVIPQEYG
                          |...... ...|. ... ..... ...... ..||...|.  |. .|    | ||. .   |.|||.|....|.
..........................edvlslfdlcaketaalgsllklssplcdlftlydtllyeyahglplpewltdellspellkqladlvnelyyy

ITKAEklEIAKGYCTPLVRKIRSDLqRTQDDdtvnklhpvysrgvlspeRHVRTRLYFTSESHVHSLLSILRYGALCNTNDSQNedggmvkemeskdeqw
.|  .  ||||  ..||...| .|| ... .                  .... .|||........|||.| .  .  ..  ..                
ltgsg..eiaklaggpllneilddl.vangp..................sdpklylyfaHdttiaallsaLglfndtlplpadl................

kramdylnvvneLNYMTQIVIMLYEDpnkdlSSEERFHVELHFSPGAKGCEE
            ..|....|. |||.     .|.....|..... |  .. .
............ppyasnlvfElyec.....psdgeyyVrvlynggtldlpr
0046349 Phosphoglycerate mutase-like 378-911 7.7e-56 183.0 In-house 5-354 (409) alignment 
Range on Protein: 378-911
Range on HMM: 5-354/409.0
MELRCVIAVIRHGDRTPKQKmkmevrhqkffdlfekcdgyksgklklkkpkqlqevldiarqllmelgqnndseieenkpkleqlktvLEMYGHFSGINR
.||..|....|||.|||..|                                                                    |.......|||.
ceLkqvqvlfRHGaRtPtkk....................................................................lsflpnwpginw

KvqltylphgcpktsseeedsrreepslllVLKWG-GELTPAGRVQAEELGRAFRCMY--PGgqgdyagfpgcgLLRLHSTYRHD-LKIYASDEGRVQMT
.                             . ..| |.||| ||.|| |||...| .|  .|            ||. .|.|..| .....||..|....
t.............................ngpcgagqLTplGreqayelGkrlrkrYvdlg............LlpsnslynpdeiyvrssdvdRtlqS

AAAFAKGLL-ALEGELTPILVQMVKSANMNGLLDSDSDslsscqqrvkarlheilqkdrdftaedyekltpsgsISLIKSMHLIKNPVKT-CDKVYSLIQ
|.||..||. .|.||..|.|.|..........  .. .                                    ||  ...  . .|... |.. ..|..
AqaflaGlfpplggeivpllrqdlldppfqpipidtvp....................................iseddalddtllppdslcpaldkllk

SLTSQIRHRMEDPKssDIQLYHSETLELMLRRWSKLEKDFKTKNGRYDISKIPD----IYDCIKYDVQHNGSLKLENTMELYRLSKALADiVIPQEYGIT
.  ....  .| ..  |..|.. |.|. . . ..|| . . ...  ...... |    .||...|.  |. .|     .  ... |.||. . ..||...
enlkslsevleflv..dealldlelldetkdllkklaerlnselpglnltdpldvasllydtllyetahglplppwcdlftpeelkvlay.ladleyyyl

KAEKlEIAKGYCTPLVRKIRSDLQRTQDDdtvnklhpvysRGVLSPERHVRTRLYFTSESHVHSLLSILRYgalcntndsqnedggmvkemeskdeqWKR
  .. |.||  ..||...| ..|... ..           ... .. .... .|||........|||.| .                          ..|
ygsg.elaklaggpllneilarledaisg...........knpvtfpldlklylyfaHdttiaallsaLgl..........................fdr

AMDYlnvVNELNYMTQIVIMLYEDpnkdlSSEERFHVELHFSPG
....    .  .|....|. |||.     .|.....|......|
lfrs...sdippyasnlvfElyec.....psdgeyyVrvlyngg
subfamily_ACP2_pd Subfamily ACP2 378-817 2.2e-10 32.6 In-house 7-262 (361) alignment 
Range on Protein: 378-817
Range on HMM: 7-262/361.0
MELRCVIAVIRHGDRTPKQKMKMEVrhqkffdlfekcdgyksgklklkkpkqlqevldiarqllmelgqnndseieenkpkleqlktvlemyghfsginr
..|. | ...|||||.|..... .                                                                            
rkLkfvqvlfRHGdRsPlntypndk...........................................................................

kvqltylphgcpktsseeedsrREEPSllLVLKWgGELTPAGRVQAEELGRAFRCMYPGGQGdyagfpgcgLLRLHsTYRHDLKIYASDEGRVQMTAAAF
                       .|..      . |.||. |  |. |||. .|  |   ..         .|      .  .... ||  |  |.| ..
......................ykede..wpqgl.GqLTeeGmqqqyeLGkfLrkrYvedtk.........fldak.ynpkqiyvrSsdvnRTlmSaqsv

AKGLLALEGEL-TP--ILVQmvksanmnglldsdsdslsscqqrvkarlheilqkdrdftaedyekLTPSGSIsLIKSMHLIKnPVKTCDKVYSLIQSLT
. ||.  |..   |  .  |                                               .|  .    .. .|.. . | |... .|.| . 
laglfppetgvdypdeqeWq..............................................pvPvhtv.seeedlllr.akknCprydellqeak

SQirHRMEdpkssdI------QlyhsetlelMLRRWSKLE-KDFKTKngryDISKIPDIYDCIKYDVQHngsLKLENTME--LYRLSKALADIVIPQEYG
..    ..             .         .|.. |.   .|.. .    .. ...| . | .   ..   |.| . ..  |..  ..||| |   |.|
es..pevk......klleenke.........lleklsestgedidle....nfyqlsdtlicerkyane...lnlpewandelfekleeladkvkeaefg

ITKAEKLEIAKGYCTPLVRKIRSDLQRTQDDDTVN-KlhpvysrgvlsperhV
. . .. |..|    ||.... ..... .. .  . |                
lnnektrelkklrgGpllnellenmkeklkceekkkk...............l
His_Phos_2 Histidine phosphatase superfamily (branch 2) 379-909 1.1e-111 366.1 Pfam-A 1-347 (347) alignment 
Range on Protein: 379-909
Range on HMM: 1-347/347.0
ELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEkcdgyksgklklkkpkqlqevldiarqllmelgqnndseieenkpkleqLKTVLEMYGHFSGINRK
||..|..||||||||||||.|..|...||..|..                                                 ||.|||..|||.|..||
eLkgvvvviRHGdRtPkqkfkksvtsekfisllk.................................................lknvlekkghfpgtkrk

vqltylphgcpktsseeedsrreePSLLLVLKWGGeLTPAGRVQAEELGRAFRCMYPggqgdyagfpgcGLLRLHSTYrHDLKIYASDEGRVQMTAAAFA
                        ..|.|.||||| ||..|| ||||||. .|..||            ||||.|.|| .|.||..|.|.||...|.|||
........................eklqlilkwgg.lThsGrkqaeelGeqlrqrYp............gllrdhlty.edvkirssserRvlaSAqafa

KGLLALEGELtpilvqmvksanmnglLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSIsliksmhLIKNPVKTCDKVYSLIQSLTSQIR
.|||..||||                | |. ..|...... | ...|. .|..... |..|. .   .        .||.. .....| .| . .. ...
aGllgpegel................llsirkdllddsnaakdtmdevkkklkellregaescpafawp.......pikvekrvvelvnklkkvmdenla

HRMEDPkssdiqlYHSETLELMLRRWSKLEKDFKTKNgRYDISKIPDIYDCIKYDVQHNGSlkLENTMELYRLskaladivipqeYGITKAEKLEIAKGY
.|....       ...|. .|. .||.||...| ... ..||||||..||..|||..||    ||.  |||.|            |||.. |||.|. ..
krlsal.......ctgednllfkerweklfreffeee.kfdiskipelydtmkydalhnrq..ledleelykl............ygigdeeklkiglll

CTPLVRKIRSDLQRTQdddtvnklhpvysrgvlsPERHVRTRLYFTSESHVHSLLSILrygALCNTNDSQnedggmvkemeskdeqwkramdylnVVNEL
..||..||.|||..||                  |.||...|||||..||...||..|    |..... .                          ..||
lnpllkkilsdleetq..................psrhaklrlyfthDshiytllnaL...gleekiare.........................aspel

NYMTQIVIMLYEDpnkdlsSEERFHVELHFS
.|..|||..||||      ||..|.|.|.||
pyasqivfelyed......sekkfyvrllfs
His_Phos_2 Histidine phosphatase superfamily (branch 2) 379-909 1.1e-111 366.1 In-house 1-347 (347) alignment 
Range on Protein: 379-909
Range on HMM: 1-347/347.0
ELRCVIAVIRHGDRTPKQKMKMEVRHQKFFDLFEkcdgyksgklklkkpkqlqevldiarqllmelgqnndseieenkpkleqLKTVLEMYGHFSGINRK
||..|..||||||||||||.|..|...||..|..                                                 ||.|||..|||.|..||
eLkgvvvviRHGdRtPkqkfkksvtsekfisllk.................................................lknvlekkghfpgtkrk

vqltylphgcpktsseeedsrreePSLLLVLKWGGeLTPAGRVQAEELGRAFRCMYPggqgdyagfpgcGLLRLHSTYrHDLKIYASDEGRVQMTAAAFA
                        ..|.|.||||| ||..|| ||||||. .|..||            ||||.|.|| .|.||..|.|.||...|.|||
........................eklqlilkwgg.lThsGrkqaeelGeqlrqrYp............gllrdhlty.edvkirssserRvlaSAqafa

KGLLALEGELtpilvqmvksanmnglLDSDSDSLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSIsliksmhLIKNPVKTCDKVYSLIQSLTSQIR
.|||..||||                | |. ..|...... | ...|. .|..... |..|. .   .        .||.. .....| .| . .. ...
aGllgpegel................llsirkdllddsnaakdtmdevkkklkellregaescpafawp.......pikvekrvvelvnklkkvmdenla

HRMEDPkssdiqlYHSETLELMLRRWSKLEKDFKTKNgRYDISKIPDIYDCIKYDVQHNGSlkLENTMELYRLskaladivipqeYGITKAEKLEIAKGY
.|....       ...|. .|. .||.||...| ... ..||||||..||..|||..||    ||.  |||.|            |||.. |||.|. ..
krlsal.......ctgednllfkerweklfreffeee.kfdiskipelydtmkydalhnrq..ledleelykl............ygigdeeklkiglll

CTPLVRKIRSDLQRTQdddtvnklhpvysrgvlsPERHVRTRLYFTSESHVHSLLSILrygALCNTNDSQnedggmvkemeskdeqwkramdylnVVNEL
..||..||.|||..||                  |.||...|||||..||...||..|    |..... .                          ..||
lnpllkkilsdleetq..................psrhaklrlyfthDshiytllnaL...gleekiare.........................aspel

NYMTQIVIMLYEDpnkdlsSEERFHVELHFS
.|..|||..||||      ||..|.|.|.||
pyasqivfelyed......sekkfyvrllfs
0053031 Phosphoglycerate mutase-like 379-934 1e-52 172.6 In-house 2-325 (342) alignment 
Range on Protein: 379-934
Range on HMM: 2-325/342.0
ELRCVIAVIRHGDRTPKQKMKMEVRHQKFFdlfekcdgyksgklklkkpkqlqevldiarqllmelgqnndseieenkpkleqlktvlemyghfsginrk
||..||...|||.|||..|.........|.                                                                      
eLkqvivlvRHGaRtPlskgpldplnewfy......................................................................

vqltylphgcpktsseeedsrreepslllvlKWG-GELTPAGRVQAEELGRAFRCMYpggqgdyagfpgCGLLrlHSTYRHD-LKIYASDEGRVQMTAAA
                               ..| ||||| || || ||||..| .|            .|||  .|||..| .....||..|....|.|
...............................pcgageLTplGreqayelGrrlrkrY............lgll..pstynpdevyvrssdvdRtlqSAqa

FAKGLLalEGELTPILVQMVKsanmnglldsdsdslsscqqrvkarlheilqkdrdftaedyekltpsgsisliksmhLIKNPVKTCDKVYSLIQSLTSQ
|..||.  ..| ||||.....                                                          .. |. |...... . .. ..
flaGlf..ppegtpilnpllg.........................................................wqpipihtepessdalllpnyd

IRHRMEDPKSSDIQL-YHSETLELMLRRWSKLEKDFKTK-NGRYDIskIPDIYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEKleI
 ......  ...... ...|.|| .| ...|| |..... ....|.  . |.||...|...|. .|    |....   |||..... ..||..  ..  .
pcpafdkllkealaseevkellerylellqklskglgltlsdlldl..vsdlydlllyelahglplppwctlftleelkalyaldllyyyglgpgne..l

AKGYCTPLVRKIRSDLQRTQDDdtvnklhpvysrgvlspERHVRTRLYFTSESHVHSLLSILRYGalcntndsqnedggmvkemeskDEQWKramdylnv
|| ...||...| ..|.... .                 ..... .|||........|||.| .                       |.|.         
aklaggpllneilarleekisg.................pldlklylyfahdttiaallsaLglf......................ddqlP........

vnelNYMTQIVIMLYEDPnkdlsseERFHVELHFSPGAKGCEEDKNLPSGYGYRPASREN
    .|....|. |||||       ....|......|  ..  . .||   |. | |.  
....pyasnlvfElyedp.......geyyVrvlynggtlseplvlplpgcdglcplsefk
0049226 Phosphoglycerate mutase-like 379-942 5.7e-51 166.7 In-house 2-333 (342) alignment 
Range on Protein: 379-942
Range on HMM: 2-333/342.0
ELRCVIAVIRHGDRTPKQKMKMEVRHQKFfdlfekcdgyksgklklkkpkqlqevldiarqllmelgqnndseieenkpkleqlktvlemyghfsginrk
.|..|...||||||||..|.........|                                                                       
kLkqvqvliRHGdRtPlakgpldflnewf.......................................................................

vqltylphgcpktsseeedsrreepslllvlkWG---GELTPAGRVQAEELGRAFRCMYpggqgdyagfpgCGLLrlHSTYRHD-LKIYASDEGRVQMTA
                                ||   ||||| ||.|| ||||..| .|            .|||  .|||..| .....||..|....|
................................wgcglgeLTplGreqayelGrrlrkrY............lgll..pstynpdevyvrssdvdRtlqSa

AAFAKGLLalEGELTPILVQMVKsanmnglldsdsdslsscqqrvkarlheilqkdrdftaedyEKLTPSGSISLIKSMHLIKnPVKTCDKVYSLIQSLT
.||..||.  ..|||||||....                                           . |  ...   ...|   | ..|.....|...| 
qaflaGlf..ppeltpilvplld.........................................wqpipiitepesndtllll.pydscpnfdkllkell

sqirhrmedpKSSDIQLYHSETLELMLRRWSKLEKDFKtkngryDISKIPD-IYDCIKYDVQHNGSLKLENTMELYRLSKALADIVIPQEYGITKAEklE
          ||...||...|.|.|. . ...|. ...      ..|...| .||...|...|. .|    . ....  |||........|||.  |  |
..........kseevqlfleeildllkklskllglnls......tlsdvadtlydlllyelahglplppwcslftleelkalyaldllyyygigyge..e

IAKGYCTPLVRKIRSDLQRTQDddtvnklhpvysrgvlsPERHVRTRLYFTSESHVHSLLSILRYGAlcntndsqnedG--Gmvkemeskdeqwkramdy
||. ...||...| ..|.....                 . .... .|||........|||.| .             .                     
iarlaggpllneilarleeaie.................gpsdlklylyfahdttiaallsalglfd...........dqlP..................

lnvvnelNYMTQIVIMLYEDPnkdlsseERFHVELHFSPGAKGCEEDKNLPSGYGYRPASRENEGRRPFKI
       .|....|. |||..       ....|......|  ..  . .||   |. | ..  |  ..| .
.......pyasnlvfElyecd.......geyyVrvlynggvlslpvtlplpgcdglcpldefkelvkkflp
0051064 Phosphoglycerate mutase-like 514-629 7.5e-06 18.6 In-house 29-171 (241) alignment 
Range on Protein: 514-629
Range on HMM: 29-171/241.0
ELTPAGRVQAEELGRAFRCM--YPGgqgdyagfpgcgllrlhstyrhdlKIYASDEGRVQMTAAAFAKGLLA--LEGELTPILVQMVKSAN---------
.||. || ||..||.... .   .                         ..|.|.  | . ||...|..|    |. ...| |  .   |          
pLtelGreqaralgerladlgikfd........................avysSpllRaiqTaeiiaealglpllpvvvdprlrEidfgalegltleeia

-------MNGLLD-------------------------------SDSDSLSSCQQRVKARLHEILQK
          | |                                .  ||  ...||.. |.|.|..
ekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellar
Rhabdo_NV Rhabdovirus Non-virion protein 827-887 7.6e-06 12.3 Pfam-A 8-67 (111) alignment 
Range on Protein: 827-887
Range on HMM: 8-67/111.0
SHVHSLLSILRYGALCNTNDSQNEDGGMVKEmESKDEQWKRAMDYLNVVNELNYMTQIVIM
.....|  .||| .         .|| .| . | .|| |.| .. .| .   . |.... |
tdiealkellrykvkvarhgflfddgdlvwr.eeddeawrrllvvvnalisskrmsrvlym