Gene EYA in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family EYA
Subfamily EYA
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP074_AA protein Get Run
MbreP074_AA_486-713 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
SH3_9 Variant SH3 domain 220-254 4.4e-08 21.9 Pfam-A 17-49 (49) alignment 
Range on Protein: 220-254
Range on HMM: 17-49/49.0
AGDWLTLERTVSDDWYEGTNlrTGARGIYPVAYVE
.|| .|...  .|.| .|..  || .| .|. |||
kGdvitvleetedgWllGel..tGrtGlvPanyVe
EYA 487-553 1e-15 47.5 In-house 3-71 (274) alignment 
Range on Protein: 487-553
Range on HMM: 3-71/274.0
TVFIWDLDETLVVFNELTNGRFARAYS--LDVNTGKYTGRALEKLVFRVLDNKLFFKKLEKMSECMLES
 |..|||||||.... | .| .| ...   |....   |. ||||.... |. .|....|.. |  |..
rvyvWdldetlillkslldGsyaekfdglkdhkksveigkrleklileladehffyeeieecdevfldd
subfamily_EYA_pd Subfamily EYA 488-551 1.1e-20 63.7 In-house 2-65 (270) alignment 
Range on Protein: 488-551
Range on HMM: 2-65/270.0
VFIWDLDETLVVFNELTNGRFARAYSLDVNTGKYTGRALEKLVFRVLDNKLFFKKLEKMSECML
|||||||||...|..|..|..|..|. |.|. ...|...|.|.|.. |.||||. ||.. . ..
vfiWdldetiiifrslltgsyatkyakdansvvalglrmeelifnladtklffndleeidqvhv
SH3_1 SH3 domain 602-649 1.7e-09 26.2 Pfam-A 1-48 (48) alignment 
Range on Protein: 602-649
Range on HMM: 1-48/48.0
RAIADLKKTIPQGLDLRQGEKLYALEEPEGGWVLARREDGSEQGLAPT
.|. | ... .. |....|.... ||. |.||. .|. .. ..|| |.
iAlYDYearesdELsfkkGDviivleksedgWwkgrlkgtgkeGliPs
SH3_2 Variant SH3 domain 602-653 1.7e-07 19.5 Pfam-A 3-53 (55) alignment 
Range on Protein: 602-653
Range on HMM: 3-53/55.0
RAIADLKKTIPQGLDLRQGEKLYAL-EEPEGGWVLARReDGSEqGLAPTTYLE
||| |.. . |..| ...|. ...| ..  .|| |... .|   ||.|....|
raiedyvgedpseLsfkkGdvikvlgskesdgwwlgev.gGrv.GlfPsslve
SH3_9 Variant SH3 domain 615-653 8.2e-09 24.2 Pfam-A 13-49 (49) alignment 
Range on Protein: 615-653
Range on HMM: 13-49/49.0
LDLRQGEKLYALEEPEGGWVLARRedGSEQGLAPTTYLE
| |..|. .. |||.|.||.|...  ....|| |..|.|
LslskGdvitvleetedgWllGel..tGrtGlvPanyVe