Gene PAPL-1 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP082_AA protein Get Run
MbreP082_AA_132-327 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 132-328 6e-37 119.4 In-house 2-189 (189) alignment 
Range on Protein: 132-328
Range on HMM: 2-189/189.0
WADMGIQNPTATSLHTQLAaandvQNGSYTLIINAGDTSCALSPGTEARVFQFRlNAPHSpgVFGLLPHSCVVPRTDADdYNLEVLDIPNSWVLDRFcfY
..|.|........ . . .     ......|||  || . ||.  .||   .|  |.  .  .   .|.  ..   . | .|.       |   .    .
fgDlgvseaaslatllkee.....eaneldliihvGDlaYalkakneavwdefm.nliep..laskvPymvsiGnhesd.snfsaykkrfsmpskne..w

YSFDYGCVHFVSFSTEHDVSRGSEQWEFVVADLKRAQaNRDKVPWIVAFTHHPFYCsSSTEPGRCgPEMDNFLE-----AFEDVFHQYGVDLFTSGHNHC
||||||.|||.|.|||.|.|.||||.... .|||.|. ||.| |||....|.|.|| |... ..|  .... ..     ..||....|.|||. |||.|.
YsfdygpvhfislstevdfslgseqykWLekdLkean.nrkktpwiivmgHrPmYc.snkdeddc.tkeetlvrkglresledllykykvdlalsgHeHs

YE
||
Ye
PAPL 231-327 3.2e-26 84.6 In-house 102-194 (194) alignment 
Range on Protein: 231-327
Range on HMM: 102-194/194.0
YYSFDYGCVHFVSFSTEHDVSRGSEQWEFVVADlkRAQANRDKVPWIVAFTHHPFYCSSSTEPGRcgPEMDNFLEAFEDVFHQYGVDLFTSGHNHCY
.|||....|||. .|.|.||.. |||.|   .|  .|..||.|.|||... | |.|||....      | ...|.|.||....|||||. .|| | |
sysfetesvhfivlsseedvkekseqyewleed..lakvnRsktPWiivmgHrpmYcsnkdkddc..kekakmlaaledllykygVDlvlaGHeHsY
subfamily_PAPL_pd Subfamily PAPL 245-326 5.9e-06 17.6 In-house 141-211 (212) alignment 
Range on Protein: 245-326
Range on HMM: 141-211/212.0
STEHDVSRGSEQWEFVVADLKRAQANrdkvpWIVAFTHHPFYCSSSTEPGRCgpemdnFLEAFEDVFHQYGVDLFTSGHNHC
.. .|||  .|||... ..||...|.     ... . |.| .  ..  | ..        .  . . ..| |. . |||.|.
egpvdvslaeeqwawleeeLkasead.....ylivaGhypvwsvaehGptki......LvkrLkPlLekynvtaylsGhDhn
ACP5 253-326 3.5e-08 25.4 In-house 132-198 (198) alignment 
Range on Protein: 253-326
Range on HMM: 132-198/198.0
GSEQWEFVVADLKRAQANRDKvPWIVAFTHHPFYCSSSTEPGRCGPEMdnfleaFEDVFHQYGVDLFTSGHNHC
 ....|  ...|..| |. ..  |.. . ||| |  .. .. ..  |.      .. ....|.||.. .|| ||
rekyaeeqlkwlekalaksta.dwkiVvGHhpvySigehgdtkelver......llpllkkykvdaYlnGHdHc
Metallophos Calcineurin-like phosphoesterase 265-327 2.3e-07 24.3 Pfam-A 140-200 (200) alignment 
Range on Protein: 265-327
Range on HMM: 140-200/200.0
KRAQANRDKVPWIVAFTHHPFYCSSSTEPGRcgPEMDNFLEAFEDVFHQYGVDLFTSGHNHCY
. |  .| .|..... ||.|...|  ..  .    ...  .|.|. . .|||||  .|| |..
flalplralvdgkilltHgplsssggsgddi..gselfgpdalekllekygvdlvlrGHtHkp