Gene PAPL-6 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP087_AA protein Get Run
MbreP087_AA_268-480 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 269-481 5.8e-62 201.0 In-house 2-189 (189) alignment 
Range on Protein: 269-481
Range on HMM: 2-189/189.0
FGDLGQHV---IDHSLQQEdmpasrnttdgiigELADKSLLFHNGDISYARGY--ESQWEEFHDQIEPIATTLPYMTAIGNHERDWpnTTSAMhgtdsgg
|||||..    ... |..|              |  . .|..| ||..||...  |..|.||...|||.|...|||..|||||.|.  ..||.       
fgDlgvseaaslatllkee..............eaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesds..nfsay.......

ecgvayETRFLMPtptLDDVWYSFDFGVMHLVVISTEHNFSVGSPQYEFVKKDLDQV-NRKNTPWLVFAGHRPFYIDSTANSTYDADQPVAKA-QRDTFE
      ..|| ||    .. |||||.| .|....|||..||.||.||....|||... |||.|||....||||.|.... .. ..... .... .|...|
......kkrfsmp...sknewYsfdygpvhfislstevdfslgseqykWLekdLkeannrkktpwiivmgHrPmYcsnkdeddctkeetlvrkglresle

DMLYEHQVDMIWGAHHHSYQ
|.||...||... .|.|||.
dllykykvdlalsgHeHsYe
PAPL 269-480 6.1e-44 142.5 In-house 3-194 (194) alignment 
Range on Protein: 269-480
Range on HMM: 3-194/194.0
FGDLGQHVIDHslqqedmpasrNTTDGIIGELADKSLLFHNGDISYARGYESQWEEFH--DQIEPIATTLPYMTAIGNHERDWPNTTSAMHGTDSGGECG
||||||.  ..           ...     .  . ....| ||..|| .....|....  .||||.|...|||.|.||||... .. .  . ...|.|.|
fGDlGqtnass...........lkrlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeeynfsnykarfsmpgseeg

VAYETRFlmptptlDDVWYSFDFGVMHLVVISTEHNFSVGSPQYEFVKKDLDQVNRKNTPWLVFAGHRPFYIDSTANStydaDQPVAKAQRDTFEDMLYE
  .....       ..  |||.....|..|.|.|....  | |||  ..|| .|||..|||....||||.|  .....    |.  ... .. .||.||.
esnsses.......gsnsysfetesvhfivlsseedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdkd....dckekakmlaaledllyk

HQVDMIWGAHHHSY
..||..  .|.|||
ygVDlvlaGHeHsY
Metallophos Calcineurin-like phosphoesterase 294-480 1.2e-15 51.4 Pfam-A 23-200 (200) alignment 
Range on Protein: 294-480
Range on HMM: 23-200/200.0
DGIIGELADKSLLFHNGDISYARGYESQWEEFH-DQIEPIATTLPYMTAIGNHERDWPNTTSAMHGTDSGGECGVAYETRFLMPTptldDvwYSFDFGVM
   |..  .  |....||....  . | ..     . ....   |.. ..|||| |  |. .  . . ..   | |...    ..    .  . . ..  
llkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangeeeyenl....k..itllttsg

HLVVISTEHNFSVGSPQYEFVKKDLDQVNRKNTPWLVFAGHRPFYIDSTANSTYdadqPVAKAQRDTFEDMLYEHQVDMIWGAHHHSY
 |...| .. .  .| |.|. ...|  ..|..... .. .|.|.. .   . .           .| .|. |....||..  .| | .
elyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi....gselfgpdalekllekygvdlvlrGHtHkp
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 500-561 1.1e-12 39.4 Pfam-A 2-62 (62) alignment 
Range on Protein: 500-561
Range on HMM: 2-62/62.0
GPVVVNLGMAGAGNSQnlEPNPSKMWQVLDDTHHGYMRF-AFTSTEVRGEYIRGDDLQAHDSF
.|| .  |.||.|.|.   ..| . |........||.|. .. .|... |..| || | .|||
ApvhIvvGaAGnglsk..fskpqpewsafresdyGysrltvvNrthLhwefvrsddgqvlDsf