Gene CDC25-1 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC3
Superfamily CC3
Family CDC25
Subfamily CDC25
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP137_AA protein Get Run
MbreP137_AA_222-330 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Subfamily.CDC25.PD 223-330 5.9e-37 117.6 In-house 4-116 (117) alignment 
Range on Protein: 223-330
Range on HMM: 4-116/117.0
VWGDGRRKFRDYIIIDARYPYEYDGGHLIGAVNFYLPDMAAEYLLARGDLS-----QTLILVHCEFSKERGPALYHYLKRVEAKACKNGGQGSLFPHLYV
..|. ......|||||.||||||.|||. ||||.|  ....|..|.. . .     .|....|||||.||||.|...|..|.....|.  .   .|.||.
lkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypelyl

LHQGYKQFHAEHP
|..|||.|..|..
LegGykeffeeve
Family.CDC25.PD 223-330 5.9e-37 117.6 In-house 4-116 (117) alignment 
Range on Protein: 223-330
Range on HMM: 4-116/117.0
VWGDGRRKFRDYIIIDARYPYEYDGGHLIGAVNFYLPDMAAEYLLARGDLS-----QTLILVHCEFSKERGPALYHYLKRVEAKACKNGGQGSLFPHLYV
..|. ......|||||.||||||.|||. ||||.|  ....|..|.. . .     .|....|||||.||||.|...|..|.....|.  .   .|.||.
lkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypelyl

LHQGYKQFHAEHP
|..|||.|..|..
LegGykeffeeve
Group.Cx5R-II.PD 223-330 5.9e-37 117.6 In-house 4-116 (117) alignment 
Range on Protein: 223-330
Range on HMM: 4-116/117.0
VWGDGRRKFRDYIIIDARYPYEYDGGHLIGAVNFYLPDMAAEYLLARGDLS-----QTLILVHCEFSKERGPALYHYLKRVEAKACKNGGQGSLFPHLYV
..|. ......|||||.||||||.|||. ||||.|  ....|..|.. . .     .|....|||||.||||.|...|..|.....|.  .   .|.||.
lkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypelyl

LHQGYKQFHAEHP
|..|||.|..|..
LegGykeffeeve
subfamily_CDC25_pd Subfamily CDC25 225-330 1e-37 119.8 In-house 4-113 (114) alignment 
Range on Protein: 225-330
Range on HMM: 4-113/114.0
GDGRRKFRDYIIIDARYPYEYDGGHLIGAVNFYLPDMAAEYLLARGDLS----QTLILVHCEFSKERGPALYHYLKRVEAKACKNGGQGSLFPHLYVLHQ
|. ..|.....|||.||||||.|||. ||||.|  ....|.||.. . .    ...|..|||||.||||.|...|..|.....|.  .   .|.||.|..
gefeekiaevliiDcRypyEyegGHikgavnlysreeveeellkkpkvkseekrkiiifhCefsseRgPklarllrevdrelnkeeypkleypelyllek

GYKQFHAEHP
|||.|..|..
GYkeffeeve
Rhodanese Rhodanese-like domain 232-327 1.4e-11 36.9 Pfam-A 12-112 (113) alignment 
Range on Protein: 232-327
Range on HMM: 12-112/113.0
RDYIIIDARYPYEYDGGHLIGAVNFYL-----------PDMAAEYLLARGD--LSQTLILVHCeFSKERGPALYHYLKRVEAKAC--KnggqgslfpHLY
 .....|.| |.||..||. ||||. |           .|  ||.|  .|    . . ..|.| .|..|.  ... |.  . |.   |           |
ekvvllDvRspeeyakghIpgAvnvpldslyprrdlffkdklaeeleesgkkldkdktvvvyc.rsgnrsggaaalllalilkelgyk.........nvy

VLHQGYKQFHA
||  |.....|
vLdGGfeawka