Gene FCP1 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily FCP1
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP091_AA protein Get Run
NvecP091_AA_147-290 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
CPDc_SM00577 148-290 5.6e-38 122.2 In-house 1-143 (146) alignment 
Range on Protein: 148-290
Range on HMM: 1-143/146.0
RKLALVVDLDQTLIHTTVQLVPANMKDV--QHFVLPghpMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDLsLFGYRIRSRDDCFN
.|. ||.|||.||.|.. .  | ....|  ......   ...... || ...||.|.||..||.|||.....||.||. .|||.  |..||. .|.|| .
kkkvLVlDLdetLvhsanmaepksfsevsptdslae...tlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkr.llkyrvlyRqdcrl

AFSKFN-DLRSLFPCGDSMVCIIDDRADVWNNAP-SLIKVKPYQFFK
  .|.. |. ||... .|.|.|||.. ....  | ...|.|||....
vkgkllkddlsllkvdlskvviiDnseestlvnpenalkikpyisal
subfamily_FCP1_pd Subfamily FCP1 149-290 1.2e-64 208.8 In-house 1-146 (146) alignment 
Range on Protein: 149-290
Range on HMM: 1-146/146.0
KLALVVDLDQTLIHTTVQ---LVPA-NMKDVQHFVLPGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDLSLFGYRIRSRDDCF
||.|||||||||||||..    |.. ..||...| || ....|..|.||....||.|..|.|||||.|||||.||..||..|||. .||. || |||...
klvLvvDlDqtlihttkdptievkeekkkdikkftlpeekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrdell

NAFSKFNDLRSLFPCGDSMVCIIDDRADVWNNAPSLIKVKPYQFFK
.|.||...|..|||..||||.||||| |||| |..|||||||.|||
dassktkklkklfptddsmvviiDDredvWnfaenlikvkpykffk
NIF NLI interacting factor-like phosphatase 151-288 4.2e-26 83.7 Pfam-A 2-132 (159) alignment 
Range on Protein: 151-288
Range on HMM: 2-132/159.0
ALVVDLDQTLIHTTVQLVPanmK--DVQHfvlpGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDLSLFGYRIrSRDDCFNAF-
 ||.|||.||.|.. .      |  . .      . . ...| ||....||....|.||. |||.....||. . ..|||.  || .|. .|..|     
tLVLDLDetLvhskekkdl...kedgkkv....eektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrl.yresctlrng

SKFNDLRSLfpcGD--SMVCIIDDRADVWNN-APSLIKVKPyqF
..  ||. |   |.  | | |.||......     .|...|  |
kyvKdLsll...grdlsrvvivDdsprsfelqpdngipiep..f
subfamily_DULLARD_pd Subfamily DULLARD 151-277 7.1e-18 56.7 In-house 3-135 (153) alignment 
Range on Protein: 151-277
Range on HMM: 3-135/153.0
ALVVDLDQTLIHTTV------QLVPANMKD-VQHFVLPGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDLSLFGYRIrSRDDC
 ||.|||.||||..       .. |   .| | .... ..|. ..   ||.   ||....|.|.| ||| ....||.... .|| . ...  |   |..|
tlvlDlDetlihsahdsvtkstvkpgtapdfvvkvlidkepvlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrry.yrqhC

FNAFSKFNDLRSLFPCGDSMVCIIDDRADVWNNA
 . ..|.    ||     | |.|.|. .  ... 
vlesgkytkdlslvssdlssviilDnspvayrkn
subfamily_CTDSPL2_pd Subfamily CTDSPL2 151-268 5.2e-17 54.2 In-house 1-116 (142) alignment 
Range on Protein: 151-268
Range on HMM: 1-116/142.0
ALVVDLDQTLIHTTVQLVPANmKDVQHFVLPGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDLSLFGYRIrSRDDCFNAFSKF
.||.|||.||.|.... ..   . ... .   . .  . . ||....||....| .|. .||  ...||. .  .|||.  |. .|.  |..|    ...
slvldldetlvhcslekleea.tltfpvlfenktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrl.frehcvcvdgny

-NDLRSLfPCGDSMVCIID
  ||. |     . . |.|
ikdlsil.Grdlektiivd
subfamily_SCP_pd Subfamily SCP 151-256 1.1e-10 33.4 In-house 2-102 (142) alignment 
Range on Protein: 151-256
Range on HMM: 2-102/142.0
ALVVDLDQTLIHTTVQLVPANmKDVQHFVLPGHPMWYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPDlSLFGYRIrSRDDCFNAfsKF
.||.|||.||.|.. . |..    |    . |     .   ||. ..||..... .|. .||     ||. .| .||   ... .|.  |. |..   | 
clvidldetlvhssfkpvkna.dfvvpveidgtvhqvyvlkrphvdeflkrvgelfevvlftaslakyadpvadlldkk.kvlrarl.frescvfh..kg

NDLRSL
| .. |
nyvkdl
subfamily_TIM50_pd Subfamily TIM50 186-271 2.2e-08 26.3 In-house 20-103 (126) alignment 
Range on Protein: 186-271
Range on HMM: 20-103/126.0
WYHTKFRPWAHKFLQKIAKFYELHIFTMGTRMYAHTIARMLDPdLSLFGYRIRSRDDCFNAFSKFNDLRSLFPcGDSMVCIIDDRA
 . .| ||  ..||...|. .|. .||  . ..|. .   |||  .|  ||.      .   ..  || .|     | | ..|  .
GwrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldP.kqlimyrlfrdatkyvdGehvkdlsklnr.dlskvivvdldk
PTCB-BRCT twin BRCT domain 631-704 4.8e-08 22.5 Pfam-A 3-63 (63) alignment 
Range on Protein: 631-704
Range on HMM: 3-63/63.0
IVFTGVIPTNlqpeKSEIWQRTLALGARISNQIVTpkdgrkdeVTTHVVAARLGTEKAYRALKAPgIKLVNPMW
|...|. ...    ......   |||| || .. .         .||....| ..||. .| |   |. |.| |
icvsgysgdd....rkrlqkliralGasiskdltk........kvTHLickraegeKyekAqkwg.ipvVspeW
BRCT BRCA1 C Terminus (BRCT) domain 632-706 3.6e-07 19.9 Pfam-A 12-75 (78) alignment 
Range on Protein: 632-706
Range on HMM: 12-75/78.0
VFtgviPTNLQPEKSEIWQRTLALGARIsnqivtpkDGRKDEVTTHVVAARL-GTEKAYRALKAPGIKLVNPMWLS
..     |  .....|. .   .||...          . .. |||.|. .   . . |.| .|..|..||. || 
yi....gtfdnfnreeleelikelGGkv........stevskktthlvvgepelrtlkylaaialnipivneeWll