Gene PAPL-3 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP099_AA protein Get Run
NvecP099_AA_142-330 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 139-320 2e-67 218.8 In-house 23-189 (189) alignment 
Range on Protein: 139-320
Range on HMM: 23-189/189.0
HTITLCIGGHDFAYDMASDMARVGDAFMNQIETMAAYTPYMVCPGNHEHACNFSDYRKRFSMPggTEGIFYSWNIGPAHIISFSTEVYYFLQfgieqlVQ
. ..| |   |.||..... ..|.| |||.||..|...||||..||||.. |||.|.||||||  ..  .||...||.|.||.||||...|.       .
neldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesdsnfsaykkrfsmp..sknewYsfdygpvhfislstevdfslg......se

QYKWLQKDLEEANlphNRAQRPWIITMGHRPMYCSNIVGDGCQNHENAIRTGitslKLFPLEELFYKHGVDLQLYGHEHSYE
|||||.|||.|||   ||...||||.||||||||||  .| |...|...|.|    .   ||.|.||..||| |.|||||||
qykWLekdLkean...nrkktpwiivmgHrPmYcsnkdeddctkeetlvrkg....lresledllykykvdlalsgHeHsYe
PAPL 143-319 1.4e-59 193.5 In-house 30-194 (194) alignment 
Range on Protein: 143-319
Range on HMM: 30-194/194.0
LCIGghDFAYDMASDMARVGDAFMNQIETMAAYTPYMVCPGNHEHACNFSDYRKRFSMPGGTEGIFYSWNIGPAHIiSFSTEVYYFLQFGIEQLVQQYKW
|..|  |.||.. .. ...|| ||.|||..||..||||.|||||...||| |..||||||..|| ..|.. |.... ||.||...|.... |. |.....
lhvG..DlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeeynfsnykarfsmpgseegesnssesgsnsy.sfetesvhfivlsseedvkekse

LQKDLEEANLPHNRAQRPWIITMGHRPMYCSNIVGDGCQNHENairtgitslKLFPLEELFYKHGVDLQLYGHEHSY
 ...|||.. . ||...||||.||||||||||   | |.....         .|. ||.|.||.||||.| ||||||
qyewleedlakvnRsktPWiivmgHrpmYcsnkdkddckekak.........mlaaledllykygVDlvlaGHeHsY
ACP5 164-317 5.6e-08 24.7 In-house 57-197 (198) alignment 
Range on Protein: 164-317
Range on HMM: 57-197/198.0
AFMNQIETMAAYTPYMVCPGNHEHACNFSDYRKRFSMPGGTEGIFYSWNIGPAHIISFSTEVYYFLQFGIEQLVQQYKWLQKDLEEANLPHNRAQRPWII
 | .  .  .  .|..|. |||..  | |   .  .    .. . . ...  ....       .  .   ..  .. |  .. |.. .   .. .  |.|
sfekiytakslqvpWyvvlGNHDyrgnvsaqieyakrskdsrfpslryslskkevvtelftekkdeksdqrevaerekyaeeqlkwlekalakstadwki

TMGHRPMYCSNIVGDGCQNHENairtgitslklfpLEELFYKHGVDLQLYGHEH
 .|| |.|     ||  .  |.             |. |. |..||. | ||.|
VvGHhpvySigehgdtkelver.............llpllkkykvdaYlnGHdH
Metallophos Calcineurin-like phosphoesterase 167-319 7.6e-19 61.8 Pfam-A 57-200 (200) alignment 
Range on Protein: 167-319
Range on HMM: 57-200/200.0
NQIETMAAYTPYMVCPGNHEHACNFSDYRKRFSMPGGTEGIFYSWNIGPAHIISFSTEVYYFLQFGIEQLVQQYKWLQKDLEEANLPHNRAQRPWIITMG
.. . .....|.....||||  .  |.|  .  ...  .|... .. .  . | . |  . .    ..    . .  .. ||| ... .||. ...| ..
ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangeeeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkillt

HRPMYCSNIVGDGCqnhenairtGITSLKLFPLEELFYKHGVDLQLYGHEHSY
|.|...|   ||           | .      ||.|..|.|||| |.||.| .
Hgplsssggsgddi.........gselfgpdalekllekygvdlvlrGHtHkp