Gene PAPL-12 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP108_AA protein Get Run
NvecP108_AA_0-146 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 1-119 3.4e-40 130.0 In-house 84-189 (189) alignment 
Range on Protein: 1-119
Range on HMM: 84-189/189.0
MPgnTESLYYSFNIG--HFISISTEFYFFTDygleliDHQYAWLENDLKEAAapeNRTFRPWIFLMGHRPMYCSNTDHDDCTMHESRVRTGipelNKPGL
||  ... .|||..|  ||||.||| .|...      ..||.|||.|||||.   ||. .|||..||||||||||.|.||||..|..||.|    ....|
mp..sknewYsfdygpvhfislstevdfslg......seqykWLekdLkean...nrkktpwiivmgHrPmYcsnkdeddctkeetlvrkg....lresl

EDILYKYGADVLIWAHEHSYE
||.||||. |.....||||||
edllykykvdlalsgHeHsYe
PAPL 1-118 1.6e-31 101.9 In-house 85-194 (194) alignment 
Range on Protein: 1-118
Range on HMM: 85-194/194.0
MPGNTESLYYSFNIG-HFISISTEFYFFTDYGLELIDHQYAWLENDLKEAAAPENRTFRPWIFLMGHRPMYCSNTDHDDCTMHESrvrtgipelNKPGLE
|||..|. ..|.. | . .|..||...|.... |   ... .  ..|.|. |..||. .|||..||||||||||.|.|||. ...          . .||
mpgseegesnssesgsnsysfetesvhfivlsseedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdkddckekak.........mlaale

DILYKYGADVLIWAHEHSY
|.||||| |. ...|||||
dllykygVDlvlaGHeHsY
Metallophos Calcineurin-like phosphoesterase 2-118 4e-15 49.6 Pfam-A 72-200 (200) alignment 
Range on Protein: 2-118
Range on HMM: 72-200/200.0
PGNTESLYYSFNIGHFISIS---------------------TEFYFFTDYGLELIDHQYAWLENDLKEAAAPENRTFRPWIFLMGHRPMYCSNTDHDDCt
.|| || .  .  |... ..                     |  .....   .  ...    |  |.| .|...|.  ....|..|.|...|   .||  
rGNHesdpgnsaygflleqlkdlrglangeeeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi.

mhesrvrtGIPELNKPGLEDILYKYGADVLIWAHEHSY
        | .. ... ||..|.||| |.....|.| .
........gselfgpdalekllekygvdlvlrGHtHkp