Gene PAPL-14 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP156_AA protein Get Run
NvecP156_AA_0-120 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 2-120 2.5e-40 130.4 In-house 73-176 (189) alignment
Range on Protein: 2-120
Range on HMM: 73-176/189.0
SNFSNYRFRFSMPgnTESLYYSFNIGPVHLISISTEFYFFTDygleliDHQYAWLENDLKEAAapeNRTLRPWIFLMGHRPMYCSNTDHDDCTMHESRVR
||||.|. |||||  ... .|||..||||.||.||| .|...      ..||.|||.|||||.   ||. .|||..||||||||||.|.||||..|..||
snfsaykkrfsmp..sknewYsfdygpvhfislstevdfslg......seqykWLekdLkean...nrkktpwiivmgHrPmYcsnkdeddctkeetlvr

TGipelNKPGLEDILYKYG
.|    ....|||.||||.
kg....lresledllykyk

PAPL 2-120 1.7e-28 92.1 In-house 74-182 (194) alignment
Range on Protein: 2-120
Range on HMM: 74-182/194.0
SNFSNYRFRFSMPGNTESLYYSFNIGPVHlISISTEFYFFTDYGLELIDHQYAWLENDLKEAAAPENRTLRPWIFLMGHRPMYCSNTDHDDCTMHESrvr
.|||||..||||||..|. ..|.. |. . .|..||...|.... |   ... .  ..|.|. |..||. .|||..||||||||||.|.|||. ...   
ynfsnykarfsmpgseegesnssesgsns.ysfetesvhfivlsseedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdkddckekak...

tgipelNKPGLEDILYKYG
       . .|||.|||||
......mlaaledllykyg

Metallophos Calcineurin-like phosphoesterase 11-120 1.7e-09 31.3 Pfam-A 69-188 (200) alignment
Range on Protein: 11-120
Range on HMM: 69-188/200.0
FSMPGNTESLYYSFNIGPVHLIS-------------------ISTEFYFFTDYGLELIDHQYAWLENDLKEAAAPENRTLRPWIFLMGHRPMYCSNTDHD
| ..|| || .  .  |. ....                   . |  .....   .  ...    |  |.| .|...|.| ....|..|.|...|   .|
fllrGNHesdpgnsaygflleqlkdlrglangeeeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgd

DCtmhesrvrtGIPELNKPGLEDILYKYG
|          | .. ... ||..|.|||
di.........gselfgpdalekllekyg