Gene EYA-1 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family EYA
Subfamily EYA
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP124_AA protein Get Run
SpurP124_AA_296-447 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
DUF2693 Protein of unknown function (DUF2693) 202-249 5.6e-06 12.8 Pfam-A 31-75 (83) alignment 
Range on Protein: 202-249
Range on HMM: 31-75/83.0
RELRSFEQDTKEEeKKEETQSsVIVFDMEDDQDRGdFDVQKFQAVNVP
.. . ||. .||| .||...| | |.|.| .. |. | ..|   ||  
kgkklfekaekee.rkEskes.vrvydvelkawRs.Frldklisvngl
subfamily_EYA_pd Subfamily EYA 295-448 9.3e-81 260.7 In-house 118-270 (270) alignment 
Range on Protein: 295-448
Range on HMM: 118-270/270.0
STKQIYDPSEEElLRRLLGPQKREQWLQLRAEIEAMTDSWLTIALKSLSIIHSRSNCINVLVTTTQLVPAVAKVLLYGLGGVFNIENVYSATRVGKESCF
  |..|.   .. .  ||||.|||.||||||||||.||||||.||||||.|.|||||.||||||||||||.|||||||||.||.|||.||||..||||.|
kvkelynsyknn.vggllgpakreawlqlraeiealtdsWltlalkslslissrsncvnvlvtttqlvpalakvllyglgsvfpieniysatkiGkesvf

ERIVARFGRKVTYVAIGDAKDEETAAKQLDFPFWRVTSHSDLAALHHALDLGYL
||||.|||.|||||.|||.||||||||.|..||||..||||||||..||||.||
erivsrfGkkvtyvvigdgkdeetaakklnlPfWrisshsdlaalysaldleyl
EYA 297-447 6.5e-58 185.9 In-house 111-273 (274) alignment 
Range on Protein: 297-447
Range on HMM: 111-273/274.0
KQIYDPSeeelLRRLLGPQKREQWLQLRAEIEAMTDSWLTIALKS---------------LSIIHSRSNCINVLVTTTQLVPAVAKVLLYGLGGVFNIEN
|..|.      | .||...|.| . .||.||. .|||||. |||.               |. |.||.|..|||||..||.||.||||||.|.....|||
kekyekg....leklldsekkealdelrseidkltdsWlssalklrlkkvcvreeadgkslleissrensvnvlvtsgqliPalakvllyrldeilaien

VYSATRVGKESCFERIVARFGR-KVTYVAIGDAKDEETAAKQLDFPFWRVTSHSDLAALHHALDLGY
||||. |||..||.||. ||.. ||..|.||| ..||||||.|..||.... |.||.|...||.|..
vysaikvGklqcfkrikerfdkpkvrfvviGdGreeetaakalklPfvkielhpdlsarfpalelkt
DUF2592 Protein of unknown function (DUF2592) 353-379 7.2e-06 13.4 Pfam-A 3-32 (41) alignment 
Range on Protein: 353-379
Range on HMM: 3-32/41.0
NVLVTTTQLVPAVAKVLL---YGLGGVFNI
. |..   .|| |  |.|   |||| ||||
kSLlfavvmVPvvmaviLGlIYGLGEvfNi
CobU Cobinamide kinase / cobinamide phosphate guanyltransferase 385-421 3.9e-06 13.7 Pfam-A 6-42 (167) alignment 
Range on Protein: 385-421
Range on HMM: 6-42/167.0
ATRVGKESCFERIVARFGRKVTYVAIGDAKDEETAAK
..| || .. |...|. |.||.|.| . |.||| |..
garSGKSefAeklaaesgkkvvYiAtaeafDeemaeR