Gene FCP1 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily FCP1
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP130_AA protein Get Run
SpurP130_AA_53-198 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
CPDc_SM00577 54-198 4.9e-34 109.4 In-house 1-143 (146) alignment 
Range on Protein: 54-198
Range on HMM: 1-143/146.0
RKLVLLVDLDQTLIHTtldEVPADMPGVHHFQLRKGPMFPWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGkFFSHRILSRDECVD
.|.||..|||.||.|.   .  |. . ... . ..  .  ....  |   ..||. ......|.|||.. . ||.|.....||..  ...|.|.|..|. 
kkkvLVlDLdetLvhs...anmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkr.llkyrvlyRqdcrl

PHSKKANL-RSIFPRGDKMVCIIDDRDDVWNFAP-NLIQVPPYRYFE
 ..|      |.... ...|.|||.. ..... | |.....||... 
vkgkllkddlsllkvdlskvviiDnseestlvnpenalkikpyisal
subfamily_FCP1_pd Subfamily FCP1 55-198 6.4e-62 200.0 In-house 1-146 (146) alignment 
Range on Protein: 55-198
Range on HMM: 1-146/146.0
KLVLLVDLDQTLIHTTLD---EVPA-DMPGVHHFQLRKGPMfpWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKFFSHRILSRDE
||||.||||||||||| |   ||.. .. ....|.|.. ..  .|....|.|...||. .|..|.|||.||| | ||...|.|.|||.|.||.|||||||
klvLvvDlDqtlihttkdptievkeekkkdikkftlpeeke..vyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrde

CVDPHSKKANLRSIFPRGDKMVCIIDDRDDVWNFAPNLIQVPPYRYFE
..|..||...|...||..|.||.|||||.||||||.|||.| ||..|.
lldassktkklkklfptddsmvviiDDredvWnfaenlikvkpykffk
NIF NLI interacting factor-like phosphatase 57-197 1.2e-23 75.7 Pfam-A 2-133 (159) alignment 
Range on Protein: 57-197
Range on HMM: 2-133/159.0
VLLVDLDQTLIHTTLDEVPadmpgvH-----HfqlrkGpMFPWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKFFsHRILSRDEC
.| .|||.||.|.. ..        .                 ... .|   ..||. .|..|.. |||.. . ||. | ...||..|.| ...|.|..|
tLVLDLDetLvhskekkdl......kedgkkv.....e.ektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklf.kkrlyresc

V--DPHSKKaNLRSIfPRGDKMVCIIDDRDDVWNF-APNLIQVPPyrYF
.  . .  | .|. .  |  . | |.||. .....   |.|...|  ..
tlrngkyvK.dLsll.grdlsrvvivDdsprsfelqpdngipiep..fy
subfamily_DULLARD_pd Subfamily DULLARD 57-193 2.7e-14 45.1 In-house 3-144 (153) alignment 
Range on Protein: 57-193
Range on HMM: 3-144/153.0
VLLVDLDQTLIHTTLDEVPAD--MPGVH-HFQ--LRKGPMFPWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKFFSHRiLSRDEC
.|..|||.||||.. |.|      ||.. .|   .    .   ..   |     ||| .|..|.| ||| ... ||..|.. .| .   ...| . |..|
tlvlDlDetlihsahdsvtkstvkpgtapdfvvkvlidkepvlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrr.yyrqhC

VDPHSKKANLRSIFPRGDKMVCIIDDRDDV-WNFAPNLIQVPP
|  ..|     |.     . |.|.|.      ... | |..  
vlesgkytkdlslvssdlssviilDnspvayrknpdnaipiks
subfamily_SCP_pd Subfamily SCP 57-199 8.6e-10 30.5 In-house 2-138 (142) alignment 
Range on Protein: 57-199
Range on HMM: 2-138/142.0
VLLVDLDQTLIHTTLDEVPADMpGVHHFQLrKGPMFPWYHTRiRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEgKFFSHRiLSRDECVDPHS
.|..|||.||.|...  |..    |   .. .| .   |  . |   ..||. ... ... .||  .  ||. ||...| . |....| | |..||  ..
clvidldetlvhssfkpvknad.fvvpvei.dgtvhqvyvlk.rphvdeflkrvgelfevvlftaslakyadpvadlldkk.kvlrar.lfrescvfhkg

KKANLRSIFPRGDKMVCIIDDRDDVWNFAPNLiQVPPYRYFEG
.     | . |  | | |.|.    . | |.   ||   .|. 
nyvkdlsrlgrdlkkviivdnspasyifhpen.avpveswfdd
subfamily_CTDSPL2_pd Subfamily CTDSPL2 58-181 8.2e-16 50.3 In-house 2-121 (142) alignment 
Range on Protein: 58-181
Range on HMM: 2-121/142.0
LLVDLDQTLIHTTLDEVPADmpgVHHFQLRKGPMFPWYHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGKFFSHRiLSRDECVDPHSK
|..|||.||.|..|....      ..|..    .    . |.|  ...||. .|. ... .||   ..||. . ...||| |.. || | |..||  ...
lvldldetlvhcslekleea...tltfpvlfenktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklikhr.lfrehcvcvdgn

KANLRSIFPRGDKMVCIIDDRDDV
     ||. |  . . |.|.    
yikdlsilGrdlektiivdnspqa
subfamily_TIM50_pd Subfamily TIM50 95-192 8.7e-06 17.9 In-house 21-117 (126) alignment 
Range on Protein: 95-192
Range on HMM: 21-117/126.0
YHTRIRDNYQQFLDLISQFYQLHIFTMGVRLYAHTVAEIIDPEGkFFSHRiLSRDECVDPHSKKANLRSIFPRGDKMVCIIDDRDDVWNFAP-NLIQVP
. .. |   ..||. ... ... .||    |.|. . . .||.. . ..| | || .   . ..    | . |  . | ..|   .  .. | | ... 
wrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldPkq.limyr.lfrdatkyvdGehvkdlsklnrdlskvivvdldkksvklqpenalalk
BRCT BRCA1 C Terminus (BRCT) domain 336-424 1.4e-07 21.2 Pfam-A 2-77 (78) alignment 
Range on Protein: 336-424
Range on HMM: 2-77/78.0
RMSVLKGCNIVFssVFPTNMPPEQSrvWKVALALGAKVspqivtkskeEQAKGRASTHLVAAKV-GTSKVHAARRSKSIFIVEPDWLWCC
......|.....  .  .|...|.    ... .||.||           ..  .  ||||. .   ... ..|  .. |.|| ..||. |
kpklFeglkfyi..gtfdnfnreel..eelikelGGkv..........stevskktthlvvgepelrtlkylaaialnipivneeWlldc
PTCB-BRCT twin BRCT domain 354-420 3.6e-10 29.4 Pfam-A 12-63 (63) alignment 
Range on Protein: 354-420
Range on HMM: 12-63/63.0
NmppeQSRVWKVALALGAKVSPQIvTKskeeqakgrASTHLVAAKVGTSKVHAARRSKsIFIVEPDW
.     .|..| . ||||..| .. ||           |||.... ...|...|.. . | .| |.|
d....rkrlqkliralGasiskdl.tk.........kvTHLickraegeKyekAqkwg.ipvVspeW
FCP1_C FCP1, C-terminal 426-459 6e-06 13.6 Pfam-A 1-35 (263) alignment 
Range on Protein: 426-459
Range on HMM: 1-35/263.0
ERWERVDERLFILADVSKHGSRSSTPG-FSDTEST
||||.|.|.|| | |   . .|. .|  | |.||.
erwekveeqlfPlkddytkkqrensPaafpdresv
FCP1_C FCP1, C-terminal 485-626 1.1e-14 42.3 Pfam-A 120-256 (263) alignment 
Range on Protein: 485-626
Range on HMM: 120-256/263.0
PGQRTKSRPLSMSEDYnPMYSFSSEDLASMGKEVEDMFGSSSGESSSSSSSS-----ESENDARS----NPTSLGSVTRPASSSSSEESLTAENPRGWKR
||   . | .||||   |.|..  ||| || |||.|..|  | .| |    .     |.|..|..    .| .    .  |.|||....  .  ||| ||
pGPsrrkrqpsmsetm.PlytlckedlesmdkevddilGegsddsdsekkkkedkeeeeeeaaqqrkqkaPeerresdvrapsssersaaggrvPrGhkr

KRDEMEDKDDDVNdfdpfqrpvedssSSAGLSEGEEWFSEEEGQKMANAID
| || ...| ...             .|   |. .|  |  |   ||.|..
kldeedeedaese.............eskessnedeeGssseademaaale