Gene PPIP5K in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily PPIP5K
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP177_AA protein Get Run
SpurP177_AA_346-937 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
RimK RimK-like ATP-grasp domain 253-351 3e-07 19.4 Pfam-A 80-177 (190) alignment 
Range on Protein: 253-351
Range on HMM: 80-177/190.0
YEEFMPTDG-TDVKVYTVGPDYAHAEARKSPalDGKVERDSHGKEVRYPVILTNSEKMIARKVCLAFKQTVCGFDLLRASGRSYVCDVNGFSFVKNSNKY
  ||. . . .|..|. || .   |  |.|   .|      .   |  .. |.. |. .| |.  |....|.| |.|..    .|..||    .|...|.
vQefIeeaenrdiRvlVvgdevvaalervsk..eGdfrsNlarGgvaeklqlseeeeelaikaaeameldvlgvDileskrgllvlEvNssvglkkiekt
0049059 Phosphoglycerate mutase-like 347-934 1.4e-58 191.9 In-house 3-416 (435) alignment 
Range on Protein: 347-934
Range on HMM: 3-416/435.0
NSNKYYDDCAKILgnMIMRELAPKYNIPWqMFTLDEEIPympttsgTMMELRCVIAVIRHGDRTPKQKM--KMEVKHPKFFSLFESYGgrskgkvklkrp
  ...|.|...||  ...  |.| ...|.  |......|       . .||..|....|||.|||..|.  |.|. ..|..||. ...            
tlapvysdgfnil..lllgtlspyfsapg.vfgisldvp.......egcelkqvqvlfRHGaRtPtsklikklealwekllslltypn............

eqlqkildvsryllgelkwqkhrsqpeieereskleqlkavlemyghfsginrkvqlkylpkgimkhssseedskGE----PSLLLILKWgGELTPAGRV
                                                                           |.    ..  ..|.. ||||| ||.
...........................................................................gplsflndwnyplga.geLTplGre

QAEELGRAFRCIYpggqgdyAGFpgcgllrlhstYRHD-LKIYASDEGRVQMTAAAFTKGMLALEgeltpilvqmvksantsglldhekesvtiqgrvke
|| |||. .|  |        ..           |..| .....||..|....|.||..|..  |                                   
qayelGkrlrkrY.......gfL...........ynpdevyvrssdvdRtlqSaqaflaGlfppe...................................

rlcqsFSRDRTFGPRDFNELAP-TGSKSLQDSLtfiknPVRMCEKVHRVIKNHTkmikdtmenpenkdfglYHHETLELMLRRWVKLEKDFKlKSGRFDI
     . ..... |.  . . |    .|..|.|     |  .| . . ..|..                  . .|.|||.|.|. || ...  .   ...
.....ilgsqllnplnvyqpvpietvdsdndtl.....pydscpafdellkell.................asdeflelflerilkllqell.pglgltp

TKVPDIYDCIKYDMQHNFI-----LKTLGFsHMDELYNSAEMLADFVIPQEYGITTseklEIGKGICTPLLKKIRSDLHRINSNDETTyrLNPLYSKGVM
..|.|.||..|||.... .     |.  .. . .|... .|.|||......||..     ||.| ...|||..| ..| .. ..|.|.  ||........
sdvldlydlckydtlllgyahglplpfcsl.fteeelevleyladlefyylygygd....eiaklaggpllneilarledaingdstn..lnltldsnpa

SPDRQVRTRLYFTSESHIHTLLSCLRY-GG-LCDESDPNWQNSCDYLGGIRELN-YMTQIVLMLYEDPSkdpmsDDRFRVELHFSPGA---KDCEDDENh
.. .... .|||.....|..|||.| . .. |    | ..... |.|  . |.. |....|. |||.|.     .....|.....      . |..... 
tfpldlklylyfaHdttiapllsaLglfddqlplpadntpfpeldrlfrtseivPyasnlvfElyecpd.....gneyyVrvlyngkvlplpgcgsgpg.

pGCCPFR
 | ||. 
.glCpld
0048946 Phosphoglycerate mutase-like 358-935 4.6e-54 177.0 In-house 2-393 (447) alignment 
Range on Protein: 358-935
Range on HMM: 2-393/447.0
ILGNMIMRELAPKYNIPWQMFTLDEEIPYMPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVkhPKFFSLFESYggrskgkvklkrpeqlqkildvsryl
.||....... . ... . ..    . . .|..  . .||..|....|||.|||..|.....  .....|....                          
llgpaladgfnillhlgtlspyfsvpgygipepvpegcelkqvqvlfRHGaRtPtkkylkgl..eplldllkna..........................

lgelkwqkhrsqpeieereskleqlkAVLEMYGHFSGINR-KVQLKYLP--KgimkhssseedskgepsllliLKWgGELTPAGRVQAEELGRAFRCIYp
                          .|||..|..|..|. |.|||. |                        ... |.||| || |. |||...|  | 
..........................nvlelggdlsflndwkyqlkneplwp.....................cgl.gqLTplGreqlyelGkrlrkrY.

ggqgdyagfpgCGLLRlhstYRHDLKIYASDEGRVQMTAAAFTKGMLALEG--ELTPILVQMVKSANTSGLLDhekesvtiqgrvkerLCQSFSrdrtfg
            |||.    .........||..|....|.||..|..  |.  . .|| ...|.| |   ||.                |. |       
...........lgllp....npseiyvrssdvdRtlqSaqaflaGlfppepplgyqpipihtvpssndnlllp...............sCpafk......

prdfnelaptgskslqdsltfiknpvrmcekvhrviknhtkmikdtmenpenKDFGLYHHETLELMLRRWVKLEKDFkLKSGRFDITKVPDIYDCIKYDM
                                                    ..   ...| |. .|... .. |.. |.   .....| |.||...|. 
....................................................ellkkelaeelkellkellerlkkl.lgglnltlsdvydlydlllyet

QHNFILKTLGFShMDELYNSAEMLADFVIPQEYGITTseklEIGKGICTPLLKKIRSDLHRINSNDEttyrlnplyskgvmspdrqvRTRLYFTSESHIH
...   .  ..   .|... .|.|||.. ..|||..     |... ...|||..| ..| .. |.|.                    . .|||.....|.
aihglsplcslf.tpeelevleyladlefyyeygygd....elarlaggpllneilarledaisgds....................klylyfaHdttia

TLLSCLrygGLCDESDPNWQNSCDYlGG---IRELN-YMTQIVLMLYEDPSKDPMSDDRFrVELHFSPGA---KDCEDDENhpGCCPFRS
.|||.|   || |   |.  .. .. ..   . |.. |....|. |||.||..|...... |......     . |.....  | ||.  
allsaL...glfddelplpadnlpf.nrlfrsseivPyasnlvfElyecpsslpsdgeyy.VrvlyngeplplpgCgsgpg..glCpldd
subfamily_PPIP5K_pd Subfamily PPIP5K 372-922 7.9e-276 905.4 In-house 4-550 (551) alignment 
Range on Protein: 372-922
Range on HMM: 4-550/551.0
NIPWQMFTLDEEIPYMPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVKHPKFFSLFESYGGRSKGKVKLKRPEQLQKILDVSRYLLGELkwqKHRSQPE
.|.... . .|..|..|||||..||||||||||||||||||||.||||.||||..|||.|.|..|..||||.|.|||..||..|.|| |.   ...|. |
eikkklalekedlPivpttsgkkmelrcviaviRHgDRtPkqklkmevthpkflelfekydgykkkevklkkpkqLqevLdivralleek...ekkseee

IEERESKLEQLKAVLEMYGHFSGINRKVQLKYLPKGIMKHSSSEEDS-KGEPSLLLILKWGGELTPAGRVQAEELGRAFRCIYPGGQGDYAGFPGCGLLR
|||..|||.|||.|||.||||||||||||||||.|...|.||.||.| . |.||||||||||||||||.||||||||||||.||||.|||||.||.||||
ieeeksklkqlknvLekyghfsGinrkvqlkylkkrtektsseeeeskreeeslllilkWGGEltpagkvqAeelGrafRclyPggdgdyaglpGlgllr

LHSTYRHDLKIYASDEGRVQMTAAAFTKGMLALEGELTPILVQMVKSANTSGLLDHEKESVTIQGRVKERLCQSFSRDRTFGPRDFNELAPTGSKSLQDS
||||||||||||||||||||||||||.||.|||||||||||||.|||||...|||..|.. ..| |||..|.. ...|..|.|.|...|||..||||...
LhstyrhdlkiyasdEgRvqmtAaafakgllaleGeltpilvqlvksanvndlLDddkdakklqdrvkkklhellqedkeftpedieklaPeksksllka

LTFIKNPVRMCEKVHRVIKNHTKMIKDTMENPENKDFGLYHHETLELMLRRWVKLEKDFKLKSGRFDITKVPDIYDCIKYDMQHNfilKTLGFSHMDELY
|..|||||....||........|..||..|....||. |||.|||||. ||| ||||.|| |...|||.|.|||||.||||.|||   |.||.....|||
lkkiknPvkvikkvvelveelvkilkdriekkkskdlrlyhsetleLlkrRWeklekeFkekekkfdiskipdiyDsikYdlqHn...kslgleqtsely

NSAEMLADFVIPQEYGITTSEKLEIGKGICTPLLKKIRSDLHRINSNDETTYRLNPLYSKGVMSPDRQVRTRLYFTSESHIHTLLSCLRYGGLCD-ESDP
. |..|||.|||||||||..|||||||.||.|||.|||.||.|....|||..||.| .||||.||.|.||||||||||||||.||..||||||.| ..| 
klakaladiviPqEYGitkeekleigkaiclpLlrkirnDlkrtekedetknrlepalskgvlsPerhvrtrlYFtsEsHihsllnvlrygglldevkde

NWQNSCDYLGGIRELNYMTQIVLMLYEDPSKDPMSDDRFRVELHFSPGAKDCE
.|....|||  ..||||.||||||||||.|||..|..||.|||.||||.|..|
qwkraldylsaleElnYltqivlmlyEdkskdasseerfsvelkfspGvktqe
0047369 Phosphoglycerate mutase-like 379-934 1.2e-55 182.4 In-house 23-418 (438) alignment 
Range on Protein: 379-934
Range on HMM: 23-418/438.0
TLDEEIP---YMPTTSGTMMELRCVIAVIRHGDRTPkQKMKMEvKHPKFFSLFESYGGRSKgkvklkrpeqlqkildvsryllgelkwqkhrsqpeieer
..  ..|   .....  . .||..|....|||.||| .|.|.. |......|.|..... .                                       
spyfsapgvglisldvpegcelkqvqvlfRHGaRtP.tksklk.kleplwellenattyps.......................................

eskleqlkavlemyghfsginrkvqlkylpkgimkhssseEDSKGEPSLLLILKWgGELTPAGRVQAEELGRAFRCIYpggqgdyagfpgcGLLrlhstY
                                        .. .  ...| .... |.||| ||.|| |||. .| .|             |||     .
........................................gplsflndwlgpcga.gqLTplGreqayelGkrlrkrY.............glL.....n

RHDL-KIYASDEGRVQMTAAAFTKGML--ALEGELTPILVQmvksantsglldhekesvtiqgrvkerlcqsfsrdrtfgprdfnelaPTGSKSLQDSLT
..|. ....||..|....|.||..|..   ..|||.|||.|                                               |    .  .|  
pedvlyvrssdvdRtlqSAqaflaGlfppegtgelapilwq...............................................pipihtipesdd

FIKN--PVRMCEKVHRViknhtkmikdtmenpenK--DFGLyhHETLELMLRRWVKLEKDFKlKSGRFDITKVPDIYDCIKYDMQHNFI--LKTLGFSHM
|. |  |  .| ... .                 .  .. .   |.|||.|... |. |..  ..  .....|.|.||...||...|    |... |   
fllnllpsdscpafdel.................lkeflas..deflelllkdilkrlkkll.pglnltpsdvldlydlcaydtlangyaglplspfcsl

--DELYNSAEMLADFVIPQEYGITTseklEIGKGICTPLLKKIRSDLHRINSNDETTYRLnPLYSKGVMSPdRQVRTRLYFTSESHIHTLLSCLRY-GGL
  .|... .|.|||.. ...||..     |..| ...|||..| ..| .. ....|.. | .|.|.||..| .... .|||.....|..||| | . .  
ftpeelevleyladlefyylygygn....elaklaggpllneilarledaingkstnlnl.tldsngvtfP.ldlklylyfaHdttiaallsaLglfddt

CD-ESDPNWQNSCDYLGGIRELN-YMTQIVLMLYEDPskdpmSDDRFRVELHFSPGA---KDCEDDENhpGCCPFR
.. ...| ...  ..|  . |.. |....|. |||.|     ||....|......     . |.....  | ||. 
wplpglpldkialnrlfrsseivPyasnlvfElyecp.....sdgeyyVrvlyngkvlplpgcgsgpg..glCpld
0046349 Phosphoglycerate mutase-like 395-934 6.1e-56 183.3 In-house 5-368 (409) alignment 
Range on Protein: 395-934
Range on HMM: 5-368/409.0
MELRCVIAVIRHGDRTPKQKmkmevkhpkffslfesyggrskgkvklkrpeqlqkildvsryllgelkwqkhrsqpeieereskleqlkavLEMYGHFSG
.||..|....|||.|||..|                                                                       |.......|
ceLkqvqvlfRHGaRtPtkk.......................................................................lsflpnwpg

INRKvqlkylpkgimkhssseedskgepslllILKWG-GELTPAGRVQAEELGRAFRCIY--PGgqgdyagfpgcgLLRLHSTYRHD-LKIYASDEGRVQ
||..                            . ..| |.||| ||.|| |||...|  |  .|            ||. .|.|..| .....||..|..
inwt............................ngpcgagqLTplGreqayelGkrlrkrYvdlg............LlpsnslynpdeiyvrssdvdRtl

MTAAAFTKGML-ALEGELTPILVQMVKSANTSGLLDHEKEsvtiqgrvkerlcqsfsrdrtfgprdfnelaptgsKSLQDSLTFIKNPVRM-CEKVHRVI
..|.||..|.. .|.||..|.|.|...... ...  .                                       |  |.| .. .|. . |.. ....
qSAqaflaGlfpplggeivpllrqdlldppfqpipidtvp...................................iseddalddtllppdslcpaldkll

KNHTKMIKDTMENPenKDFGLYHHETLELMLRRWVKLEKDFKLKSGRFDITKVPD----IYDCIKYDMQHNFILKTLGFSHMDELYNSAEMladfVIPQE
|.. | ... .| .  .|  |...|.|. . . . || . . ..   ...|.. |    .||...|.  |.. |  ..    .|...  ..    . ..|
kenlkslsevlefl..vdealldlelldetkdllkklaerlnselpglnltdpldvasllydtllyetahglplppwcdlftpeelkvlay....ladle

YGITTSEKlEIGKGICTPLLKKIRSDLHRINSNdettyrlnplysKGVMSPDRQVRTRLYFTSESHIHTLLSCLRYgglcdesdpnWQNSCDYlggIREL
|....... |..| ...|||..| ..| .. |.            |..... .... .|||.....|..||| | .          .... ..    .  
yyylygsg.elaklaggpllneilarledaisg............knpvtfpldlklylyfaHdttiaallsaLgl..........fdrlfrs...sdip

NYMTQIVLMLYEDpskdpMSDDRFRVELHFSPGAKDCedDENHPGcCPFR
.|....|. |||.      ||... |......|  ..   ....| ||. 
pyasnlvfElyec.....psdgeyyVrvlynggplpl..pgcgeg.cpls
0048439 Phosphoglycerate mutase-like 395-933 1.2e-49 162.7 In-house 7-379 (391) alignment 
Range on Protein: 395-933
Range on HMM: 7-379/391.0
MELRCVIAVIRHGDRTPKQKMKM--EVKHPKffslfesyggrskgkvklkrpeqlqkildvsryllgelkwqkhrsqpeieereskleqlkavlemyghf
.||..|....|||.|||......  .  ..|                                                                     
celkqvqvlfRHGaRtPtssypnkldpllnk.....................................................................

sginrkvqlkylpkgimkhssseedskgepsLLLILKWG-GELTPAGRVQAEELGRAFRCIYpggqgdyagfPGCGLLRLHSTY-RHDLKIYASDEGRVQ
                               ||.. ..| ||||| || |. ||||..|  |          .  |||. ..|. ........||..|..
...............................llpngpcglgeLTplGreqlyelGrrlrkrY..........vdlgllpskytlnpsevyvrssdvdRtl

MTAAAFTKGMLAlEGELTPILVQMVKSAntsglldhekesvtiqgrvkerlcqsfsrD---------------------------RTFGPRDFNELAPTG
..|.||..|..  ...||.|||..|.|.                             |                           |.. .  ...||.  
qSAqaflaGlfp.plgltvilvivvese.............................dpllnplpintcplledlllldalsalprfylseilerlaevl

SKSLQDSLTFiknpvrmcekvhrviknhtkmikdtmenpenkdfglyhhETLELMLRRWVKLEKDFKLKSGR-FDITKVPDIYDCIKYDMQHNFILKTLG
.. |.  ||.                                       |...... .. |. ...  .... ...... ..||...|.. |.. |   .
nrvlglnlta.......................................edvlslfdlcaketaalgsllklssplcdlftlydtllyeyahglplpewl

FShmdELYNS--AEMLADFVIPQEYGITTSEklEIGKGICTPLLKKIRSDLhRINSNdettyrlnplyskgvmspdRQVRTRLYFTSESHIHTLLSCLry
..   ||..   ...|||.|....|..| |.  ||.| ...|||..| .|| ..|..                   .... .|||.....|..||| |  
td...ellspellkqladlvnelyyyltgsg..eiaklaggpllneilddl.vangp...................sdpklylyfaHdttiaallsaL..

gGLCDESDPN---WqnscdylggireLNYMTQIVLMLYEDPSkdpmsDDRFRVELHFSPGAKDCED--------------DENHPG-------CCPF
 || . . |.   .            ..|....|. |||.||     |....|..... |  |. .                  ||        ||.
.glfndtlplpadl............ppyasnlvfElyecps.....dgeyyVrvlynggtldlprdltlldldefllrlvlplpgcgsgpgglCpl
subfamily_ACP2_pd Subfamily ACP2 395-933 4e-11 35.0 In-house 7-337 (361) alignment 
Range on Protein: 395-933
Range on HMM: 7-337/361.0
MELRCVIAVIRHGDRTPKQKMKMEVkhpkffslfesyggrskgkvklkrpeqlqkildvsryllgelkwqkhrsqpeieereskleqlkavlemyghfsg
..|. | ...|||||.|..... .                                                                            
rkLkfvqvlfRHGdRsPlntypndk...........................................................................

inrkvqlkylpkgimkhssseedskgeP------SlllilKWgGELTPAGRVQAEELGRAFRCIYPGGQGdyagfpgcgLLRLHsTYRHDLKIYASDEGR
                                  .      . |.||. |  |. |||. .|  |   ..         .|      .  .... ||  |
...........................ykedewpq.....gl.GqLTeeGmqqqyeLGkfLrkrYvedtk.........fldak.ynpkqiyvrSsdvnR

VQMTAAAFTKGMLALegeltpilV-----------QmvksantsglldhekesvtiqgrvkerlcqsfsrdrtfgprdfneLAPTGSKSLQDS-LTFikn
  |.| ... |..                      |                                               |  ..| ... |.    
TlmSaqsvlaglfpp........etgvdypdeqeWq.............................................pvPvhtvseeedlllr...

PVRMCEKVHRVIKNHTKMiKDT-MENPENKDfglyhhetlelMLRRWVKLE-KDFKLKsgrfDITKVPDIYDCIKYDMQHnfiLKTLGFSHMdELYNSAE
. . |.... ....  .  ..   .. |||.           .|..  .   .|..|.    .. ...| . | .   ..   |.   . .  ||.. .|
akknCprydellqeakes.pevkklleenke...........lleklsestgedidle....nfyqlsdtlicerkyane...lnlpewand.elfekle

MLADFVIPQEYGITTSEKLEIGKGICTPLLKKIRSDLHRINSNDETTYRlnplyskgvmspdrqvrTRLYFTSeSHIHTLLSCLRYGGLCdesdpnwqns
 ||| |   |.|. .... |. |    |||... ... ......|.  .                  .|.. | .| .||.. |.  |.           
eladkvkeaefglnnektrelkklrgGpllnellenmkeklkceekkkk.................lklflYS.aHDttlaalLeaLgif..........

cdylGGiRELNYMTQIVLMLYEDpskdpmSDDRFRVELHFSPGAKDCEDDENHPGC-----CPF
     . .  .|.. |.  |||.      .|. . |.. .    .. . . ..|||     || 
....ek.kappyasaiivElyee......ddgkplvkvlyrnetskdppeltlpgCkgeedCpl
His_Phos_2 Histidine phosphatase superfamily (branch 2) 396-915 8.5e-103 336.8 Pfam-A 1-347 (347) alignment 
Range on Protein: 396-915
Range on HMM: 1-347/347.0
ELRCVIAVIRHGDRTPKQKMKMEVKHPKFFSLFEsyggrskgkvklkrpeqlqkildvsryllgelkwqkhrsqpeieereskleqLKAVLEMYGHFSGI
||..|..||||||||||||.|..|...||.||..                                                    ||.|||..|||.|.
eLkgvvvviRHGdRtPkqkfkksvtsekfisllk....................................................lknvlekkghfpgt

NRKvqlkylpkgimkhssseedskgePSLLLILKWGGeLTPAGRVQAEELGRAFRCIYPggqgdyagfpgcGLLRLHSTYrHDLKIYASDEGRVQMTAAA
.||                       ..|.||||||| ||..|| ||||||. .|. ||            ||||.|.|| .|.||..|.|.||...|.|
krk.......................eklqlilkwgg.lThsGrkqaeelGeqlrqrYp............gllrdhlty.edvkirssserRvlaSAqa

FTKGMLALEGELtpilvqmvKSANTSGLLDHEKESVTIQGRVKERLCQSFSRDRtFGPRDFNELaptgskslqdsltFIKNPVRMCEKVHRVIKNHTKMI
|..|.|..||||           . . |||  .  . ..  ||..| .   ...   .  |..               ||.. |..|.|.   |.... .
faaGllgpegel........llsirkdllddsnaakdtmdevkkklkellrega.escpafawp.............pikvekrvvelvnklkkvmdenl

KDTMENPenkdfglYHHETLELMLRRWVKLEKDFKLKSgRFDITKVPDIYDCIKYDMQHNFIlktlgFSHMDELYNSaemladfvipqeYGITTSEKLEI
.. ....       .. |. .|. .|| ||...|  .  .|||.|.|..||..|||..||       .....|||.             |||...|||.|
akrlsal.......ctgednllfkerweklfreffeee.kfdiskipelydtmkydalhnrq.....ledleelykl............ygigdeeklki

GKGICTPLLKKIRSDLHRINsndettyrlnplyskgvmsPDRQVRTRLYFTSESHIHTLLSCLrygGLCDESDPNwqnscdylgGIRELNYMTQIVLMLY
| ....||||||.|||.. .                   |.|....|||||..|||.|||..|   ||.......         ...||.|..|||..||
gllllnpllkkilsdleetq...................psrhaklrlyfthDshiytllnaL...gleekiare.........aspelpyasqivfely

EDpskdpmSDDRFRVELHFS
||      |...|.|.|.||
ed......sekkfyvrllfs
His_Phos_2 Histidine phosphatase superfamily (branch 2) 396-915 8.5e-103 336.8 In-house 1-347 (347) alignment 
Range on Protein: 396-915
Range on HMM: 1-347/347.0
ELRCVIAVIRHGDRTPKQKMKMEVKHPKFFSLFEsyggrskgkvklkrpeqlqkildvsryllgelkwqkhrsqpeieereskleqLKAVLEMYGHFSGI
||..|..||||||||||||.|..|...||.||..                                                    ||.|||..|||.|.
eLkgvvvviRHGdRtPkqkfkksvtsekfisllk....................................................lknvlekkghfpgt

NRKvqlkylpkgimkhssseedskgePSLLLILKWGGeLTPAGRVQAEELGRAFRCIYPggqgdyagfpgcGLLRLHSTYrHDLKIYASDEGRVQMTAAA
.||                       ..|.||||||| ||..|| ||||||. .|. ||            ||||.|.|| .|.||..|.|.||...|.|
krk.......................eklqlilkwgg.lThsGrkqaeelGeqlrqrYp............gllrdhlty.edvkirssserRvlaSAqa

FTKGMLALEGELtpilvqmvKSANTSGLLDHEKESVTIQGRVKERLCQSFSRDRtFGPRDFNELaptgskslqdsltFIKNPVRMCEKVHRVIKNHTKMI
|..|.|..||||           . . |||  .  . ..  ||..| .   ...   .  |..               ||.. |..|.|.   |.... .
faaGllgpegel........llsirkdllddsnaakdtmdevkkklkellrega.escpafawp.............pikvekrvvelvnklkkvmdenl

KDTMENPenkdfglYHHETLELMLRRWVKLEKDFKLKSgRFDITKVPDIYDCIKYDMQHNFIlktlgFSHMDELYNSaemladfvipqeYGITTSEKLEI
.. ....       .. |. .|. .|| ||...|  .  .|||.|.|..||..|||..||       .....|||.             |||...|||.|
akrlsal.......ctgednllfkerweklfreffeee.kfdiskipelydtmkydalhnrq.....ledleelykl............ygigdeeklki

GKGICTPLLKKIRSDLHRINsndettyrlnplyskgvmsPDRQVRTRLYFTSESHIHTLLSCLrygGLCDESDPNwqnscdylgGIRELNYMTQIVLMLY
| ....||||||.|||.. .                   |.|....|||||..|||.|||..|   ||.......         ...||.|..|||..||
gllllnpllkkilsdleetq...................psrhaklrlyfthDshiytllnaL...gleekiare.........aspelpyasqivfely

EDpskdpmSDDRFRVELHFS
||      |...|.|.|.||
ed......sekkfyvrllfs
0053031 Phosphoglycerate mutase-like 396-937 4.6e-51 167.1 In-house 2-316 (342) alignment 
Range on Protein: 396-937
Range on HMM: 2-316/342.0
ELRCVIAVIRHGDRTPKQKMKMEVKHPKFFslfesyggrskgkvklkrpeqlqkildvsryllgelkwqkhrsqpeieereskleqlkavlemyghfsgi
||..||...|||.|||..|....... .|.                                                                      
eLkqvivlvRHGaRtPlskgpldplnewfy......................................................................

nrkvqlkylpkgimkhssseedskgepslllilKWG-GELTPAGRVQAEELGRAFRCIYpggqgdyagfpgCGLLrlHSTYRHD-LKIYASDEGRVQMTA
                                 ..| ||||| || || ||||..| .|            .|||  .|||..| .....||..|....|
.................................pcgageLTplGreqayelGrrlrkrY............lgll..pstynpdevyvrssdvdRtlqSA

AAFTKGMLalEGELTPILVQMVKsantsglldhekesvtiqgrvkerlcqsfsrdrtfgprdfnelaptgskslqdsltFIKNPVRMCEKVHRVIKNHTK
.||..|..  ..| ||||.....                                                        ... |. ....... . .  .
qaflaGlf..ppegtpilnpllg........................................................wqpipihtepessdalllpny

MIKDTMENPENKDFGL-YHHETLELMLRRWVKLEKDFKLK-SGRFDItkVPDIYDCIKYDMQHNFILKTLGFShmdELYNSAEMLADFVIPQEYGITTSE
.  .....  .... . .. |.|| .| .. || |...|. |...|.  | |.||...|...|.. |         .... .. |..... ..||.. ..
dpcpafdkllkealaseevkellerylellqklskglgltlsdlldl..vsdlydlllyelahglplppwctl...ftleelkalyaldllyyyglgpgn

KleIGKGICTPLLKKIRSDLHRINSNdettyrlnplyskgvmspDRQVRTRLYFTSESHIHTLLSCLrygGLCDESDPnwqnscdylggirelNYMTQIV
.  ..| ...|||..| ..| .. |.                   . .. .|||.....|..|||.|   ||.|.  |               .|....|
e..laklaggpllneilarleekisg..................pldlklylyfahdttiaallsaL...glfddqlP...............pyasnlv

LMLYEDPskdpmsdDRFRVELHFSPGAKDCEDDENHPGCcpfrsvH
. |||||       ....|......|  ..  . . |||      .
fElyedp.......geyyVrvlynggtlseplvlplpgc......d
0049226 Phosphoglycerate mutase-like 396-933 5e-48 157.1 In-house 2-321 (342) alignment 
Range on Protein: 396-933
Range on HMM: 2-321/342.0
ELRCVIAVIRHGDRTPKQKMKMEVKHPKFfslfesyggrskgkvklkrpeqlqkildvsryllgelkwqkhrsqpeieereskleqlkavlemyghfsgi
.|..|...||||||||..|.........|                                                                       
kLkqvqvliRHGdRtPlakgpldflnewf.......................................................................

nrkvqlkylpkgimkhssseedskgepslllilkWG---GELTPAGRVQAEELGRAFRCIYpggqgdyagfpgCGLLrlHSTYRHD-LKIYASDEGRVQM
                                  ||   ||||| ||.|| ||||..| .|            .|||  .|||..| .....||..|...
..................................wgcglgeLTplGreqayelGrrlrkrY............lgll..pstynpdevyvrssdvdRtlq

TAAAFTKGMLalEGELTPILVQMVKsantsglldhekesvtiqgrvkerlcqsfsrdrtfgprdfNELAPTGSKSLQDSLTFIKnPVRMCEKVHRVIKNH
.|.||..|..  ..|||||||....                                          . |. . .   . ..   |  .| ......|. 
SaqaflaGlf..ppeltpilvplld........................................wqpipiitepesndtllll.pydscpnfdkllkel

TkmikdtmenpENKDFGLYHHETLELMLRRWVKLEKDFKlksgrfDITKVPD-IYDCIKYDMQHNFILKTLGFShmdELYNSAEMLADFVIPQEYGITTS
            .... |...|.|.|. . . .|. ...      ....|.| .||...|. .|.. |  .      .... .. |........|||. .
l..........kseevqlfleeildllkklskllglnls......tlsdvadtlydlllyelahglplppwcsl...ftleelkalyaldllyyygigyg

EklEIGKGICTPLLKKIRSDLHRINSndettyrlnplyskgvmsPDRQVRTRLYFTSESHIHTLLSCLRYGGlcdESDPnwqnscdylggirelNYMTQI
|  ||.. ...|||..| ..| .. .                  . . .. .|||.....|..|||.| . .   .  |               .|....
e..eiarlaggpllneilarleeaie..................gpsdlklylyfahdttiaallsalglfd...dqlP...............pyasnl

VLMLYEDPskdpmsdDRFRVELHFSPGAKDCEDDENHPGC---CPF
|. |||..       ... |......|  ..  . . |||   ||.
vfElyecd.......geyyVrvlynggvlslpvtlplpgcdglcpl
CAS_CSE1 CAS/CSE protein, C-terminus 671-726 4.6e-06 11.4 Pfam-A 54-107 (435) alignment 
Range on Protein: 671-726
Range on HMM: 54-107/435.0
LTFIKNPVRMCekVHRVIKNHTKMIKDTMENPENKDFGLYHHETLELMLRRWVKLE
|...|. |  .  .. |... |....   .||.|  |  |. |.| ...|   | .
livlkeavlpv..adtvlqkLteilevvskNPsnPrFnhYlFEalgaliriaakad