Gene FCP1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily FCP1
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP162_AA protein Get Run
AqueP162_AA_90-234 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_FCP1_pd Subfamily FCP1 92-233 1.1e-61 199.2 In-house 1-145 (146) alignment 
Range on Protein: 92-233
Range on HMM: 1-145/146.0
KLALIIDLDQTLIHTSID---RNIERGLPDVHSFTLPGHSCVYHCRLRPYVREFLNHISQYYELHVATMGTRDYADAITKILDQEKKLFSHRVISRNELL
||.|..|||||||||..|   .. |.   |...|||| ...||...|||...|||...|..||||..|||||.||..|.||||.||||||.|..||.|||
klvLvvDlDqtlihttkdptievkeekkkdikkftlpeekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrdell

DPHSKAVRLKSVFPCGDEMVAIMDDRGDVWGHRPNLIHVKAYVFF
|..||. .||..||..|.|| |.|||.||| ...|||.||.|.||
dassktkklkklfptddsmvviiDDredvWnfaenlikvkpykff
CPDc_SM00577 91-234 6.8e-33 105.7 In-house 1-143 (146) alignment 
Range on Protein: 91-234
Range on HMM: 1-143/146.0
RKLALIIDLDQTLIHTsidrNIERGLPDVHSFTLPGHS--CVYHCRLRPYVREFLNHISQYYELHVATMGTRDYADAITKILDQEKkLFSHRVISRNELL
.|. |..|||.||.|.    . ... . ... . . ..  . ... .||||.|||.......||.. |.....|||.| ..|| .. |...||..|..  
kkkvLVlDLdetLvhs....anmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkr.llkyrvlyRqdcr

DPHSKAVRL-KSVFPCGDEMVAIMDDRGDVWGHRP-NLIHVKAYVFFA
  ..| ..   |.... ...| |.|.. ... . | |.. .| |... 
lvkgkllkddlsllkvdlskvviiDnseestlvnpenalkikpyisal
NIF NLI interacting factor-like phosphatase 94-232 4.4e-24 77.2 Pfam-A 2-132 (159) alignment 
Range on Protein: 94-232
Range on HMM: 2-132/159.0
ALIIDLDQTLIHTSIDRNIerglpD-----VhsftlpGHSCVYHCRLRPYVREFLNHISQYYELHVATMGTRDYADAITKILDQEKKLFsHRVISRNEL-
 |..|||.||.|.. . .            |       ... ..  .||...|||...|..||. . |.....||... ..||..|||| .....|..  
tLVLDLDetLvhskekkdl.....kedgkkv......eektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklf.kkrlyresct

LDPHSKAVRLKSVfpcGD--EMVAIMDDRGDVW-GHRPNLIHVKAyvF
|  ...   |. .   |.  . | | ||. ...  .. |.|...   |
lrngkyvKdLsll...grdlsrvvivDdsprsfelqpdngipiep..f
subfamily_DULLARD_pd Subfamily DULLARD 94-230 1.8e-18 58.7 In-house 3-145 (153) alignment 
Range on Protein: 94-230
Range on HMM: 3-145/153.0
ALIIDLDQTLIHTSIDRN-----IERGLPD-VHSFTLPGHSCVYHCRLRPYVREFLNHISQYYELHVATMGTRDYADAITKILDQEKKLFSHRVISRNEL
 |..|||.||||. .|.       ..  || |  ... .......   ||.| .||. .|..|.| . | ... ||.|..  ||... ....|    . .
tlvlDlDetlihsahdsvtkstvkpgtapdfvvkvlidkepvlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCv

LDPHSKAVRLKSVFPCGDEmVAIMDDRG-DVWGHRPNLIHVKAY
|.  .    |  | .  .. | |.|.   .   .  | |..|..
lesgkytkdlslvssdlss.viilDnspvayrknpdnaipiksw
subfamily_CTDSPL2_pd Subfamily CTDSPL2 95-182 1.2e-15 49.7 In-house 2-87 (142) alignment 
Range on Protein: 95-182
Range on HMM: 2-87/142.0
LIIDLDQTLIHTSIDRNIERGLPDVHSFtlPGHSCVYHCRLRPYVREFLNHISQYYELHVATMGTRDYADAITKILDQEKKLFSHRVI
|..|||.||.|.|...  |  |    .|    .    . ||||..||||...|. .|. . |  .. ||| . ..|| ||||. ||. 
lvldldetlvhcslekleeatltfpvlf..enktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlf
PTCB-BRCT twin BRCT domain 602-674 8.5e-13 37.8 Pfam-A 3-63 (63) alignment 
Range on Protein: 602-674
Range on HMM: 3-63/63.0
LLFTGIIPTNmnpeKSREWNTTRAFGGEIHSTLvTTpapddeHTTHIIVGKKDTDKYKQALRIPgIEIVSPEW
. ..|. ...    ..| ... ||.|..|. .| |.      ..|| |. .. ..||..| .   | .|||||
icvsgysgdd....rkrlqkliralGasiskdl.tk......kvTHLickraegeKyekAqkwg.ipvVspeW
subfamily_SCP_pd Subfamily SCP 94-183 2.2e-11 35.7 In-house 2-88 (142) alignment 
Range on Protein: 94-183
Range on HMM: 2-88/142.0
ALIIDLDQTLIHTSIdRNIERGlPDVHSFTLPGHSCVYHCRLRPYVREFLNHISQYYELHVATMGTRDYADAITKILDQEkKLFSHRVIS
.|.||||.||.|.|. . ..     | .  . |     .   ||.| |||..... .|. . |     ||| .. .||.. |....|.. 
clvidldetlvhssf.kpvkna.dfvvpveidgtvhqvyvlkrphvdeflkrvgelfevvlftaslakyadpvadlldkk.kvlrarlfr
BRCT BRCA1 C Terminus (BRCT) domain 596-678 2.7e-10 29.9 Pfam-A 5-77 (78) alignment 
Range on Protein: 596-678
Range on HMM: 5-77/78.0
VFSGLRLLFtgiiP--TNMNPEKSreWNTTRAFGGEIhstlvttPAPDDEHTTHIIVGKK-DTDKYKQALRIPGIEIVSPEWFWDC
.|.||.  .       .|.|.|.    .. ...||..          ... |||..||.  .... ..|   ..| ||..||..||
lFeglkfyi....gtfdnfnreel..eelikelGGkv.......stevskktthlvvgepelrtlkylaaialnipivneeWlldc