Gene PAPL-1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP166_AA protein Get Run
AqueP166_AA_273-376 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 275-363 1.1e-23 76.1 In-house 2-78 (189) alignment 
Range on Protein: 275-363
Range on HMM: 2-78/189.0
FGDMGEAQVDDTLQPIHAQppainntnlmakEVNERDLVLHIGDISYARGY--AGVWDEFFDLIQPISSRVPYMVCGGNHERDYphSGSYY
|||.|  . ... .  . .            | || ||..|.||..||...  . |||||..||.|..|.|||||. ||||.|.  . |.|
fgDlgvseaaslatllkee............eaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesds..nfsay
PAPL 274-376 2.7e-21 68.6 In-house 2-94 (194) alignment 
Range on Protein: 274-376
Range on HMM: 2-94/194.0
AFGDMGEAQVDDtlqpihaqppaiNNTNLMAKEVNERDLVLHIGDISYARGYAGVWDEFF--DLIQPISSRVPYMVCGGNHERDYPHSGSYYEGTDSGGE
.|||.|... .             ...   ... .. |..||.||..|| ..   ||..   ..|.|....|||||. ||||..| .|..... ...|.|
vfGDlGqtnass............lkrlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeeynfsnykarfsmpgse

CGVPY
.|  .
egesn
PhoD PhoD-like phosphatase 197-330 1.9e-09 28.0 Pfam-A 52-152 (453) alignment 
Range on Protein: 197-330
Range on HMM: 52-152/453.0
IRTQAATSNKYTSKdmcgppattvgyidpgmlhtAKLSGLTPGQEYNYQFGD--DPEWSQVFSFRMPPAPSPNAsITFIAFGDMGE-AQVddtlqpihaq
 ...| ....|| |                    ....|| ||||| |.|    . . |.| ..|  |. .... ... .....   .            
gtvlatserdytvk....................vevtgLepgqeyfYrfraeegesespvGrtrTlpeaaves.lrlavvSCsnyeqGy..........

ppaINNTNLMAKEvNERDLVLHIGDISYARGYaGVWD
   .|  . .|.. .. |.|||.||. |..|  |...
...fnayrelaek.edlDfvlhlGDyiYeyge.gtyk
Metallophos Calcineurin-like phosphoesterase 290-361 3.9e-08 26.8 Pfam-A 9-84 (200) alignment 
Range on Protein: 290-361
Range on HMM: 9-84/200.0
IHAQPPAI---NNTNLMAKEVNERDLVLHIGDISYARGYAGVWDEFF-DLIQPISSRVPYMVCGGNHERDYPHSGS
.| ..       .  |.. . .. ||||. ||....  ..  .   .  | ....  .|.... |||| |.  | .
lHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsay