acp-4, Gene Page

Gene acp-4 in Caenorhabditis elegans

Synonym: CELE_F14E5.6, acp-4

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level	Class	Gene list	Wiki page
Fold	HP
Superfamily	HP
Family	HP2
Subfamily	ACP2

Protein sequence

ID	Type	Fasta	BLAST phosphatome	Note
CeleP004_AA	protein	Get	Run
CeleP004_AA_78-338	phosphatase_domain	Get	Run

Domains

Summary

Details

Domain	Domain Description	Range	Significance	Score	Source	Profile Range (length)	Alignment
subfamily_ACP2_pd	Subfamily ACP2	93-338	8.3e-56	182.0	In-house	5-269 (361)	alignment
Range on Protein: 93-338 Range on HMM: 5-269/361.0 PIRRLIFAHTIFRHGSRAPSK-----NANNTYYPRGRGQLTDRGYNHSFMLGRFLKKRY-VGTGFLSDFMKPSEMEWRFRAVERCLATASAVAAGMFKT- \|.\|.\| ...\|\|\|\|.\|.\|.. . ... .\|.\| \|\|\|\|..\|......\|\|.\|\|.\|\|\| . \|.\|\|.. ..\|.....\|. \|.\|.\|..\|..\|.\|\|.\|.. eerkLkfvqvlfRHGdRsPlntypndkykedewpqglGqLTeeGmqqqyeLGkfLrkrYvedtkfldakynpkqiyvrSsdvnRTlmSaqsvlaglfppe ------EERKWLTVPITTNHANQDKLLNtPVHSCDIFESAMEKACPNLEADNHRDESAIMYECAGSNHP--IFQKISIDDSDKYIN--DYKNNVPVPDFI .\|..\| .\|\|..\|.....\|.\|\|. . ..\|.........\|. . \| ... .\|.....\|. ... \| .. ... \|\|..\| .\|.\|....\|... tgvdypdeqeWqpvPvhtvseeedlllr.akknCprydellqeakespevkklleenkelleklsestgedidlenfyqlsdtlicerkyanelnlpewa C----ENIEVISEEYMKYRNLKNGIGKPVIIKFRFGVLIDTLLENLKTAWTNNLANKEsLKFKVYST \|..\| .......... \| .. . \|.\|.\|.\|...\|\|\|\|.\|....... .\|. \|\|. .\|\|. ndelfekleeladkvkeaefglnnektrelkklrgGpllnellenmkeklkceekkkk.lklflYSa
0048946	Phosphoglycerate mutase-like	79-338	2.1e-36	118.8	In-house	16-304 (447)	alignment
Range on Protein: 79-338 Range on HMM: 16-304/447.0 VHTSSTPYPVTQTNPIR-------RLIFAHTIFRHGSRAPSKNA--------------------------NNT--------YYPRGRGQLTDRGYNHSFM . ..\|\|.. .. .\| .\|.... .\|\|\|\|.\|.\|.\|. \|.. ..\| \| \|\|\|\|..\|. .. hlgtlspyfsvpgygipepvpegcelkqvqvlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkneplwpcglgqLTplGreqlye LGRFLKKRYvgTGFLSdfmKPSEMEWRFRAVERCLATASAVAAGMFKTE-ERKWLTVPITTNHANQDKLLNTpvhSCDIFESAMEKACPNLEADNHRDES \|\|..\|.\|\|\| .\|.\|. \|\|\|. .\| \|.\|.\|..\| \|..\|\|.\| \| .. ..\|\| \| . .\| \|\|.. \|\|. \|.. . \|.. .. ... lGkrlrkrY..lgllp...npseiyvrssdvdRtlqSaqaflaGlfppepplgyqpipihtvpssndnlllp...sCpafkellkkelaeelkellkell AIMYECAG-SNHPIFQKISIDDSDKYINDYKNNVPVPDFI-CENIEVISEEYMKYRNLKNGIGKPvIIKFRFGVLIDTLLENLKTAWTNNLankeslKFK . ... .\| .\| . . .. \| .\| . . .\| .... \| .\|\|. . . . ...\|.\| . . . ..\|.\|.. .\|..\|. \|. .. \|. erlkkllgglnltlsdvydlydlllyetaihglsplcslftpeelevleyladlefyyeygygde.larlaggpllneilarledaisgds......kly VYST .\|.. lyfa
0049059	Phosphoglycerate mutase-like	95-338	8.6e-36	116.8	In-house	41-329 (435)	alignment
Range on Protein: 95-338 Range on HMM: 41-329/435.0 RRLIFAHTIFRHGSRAPSKNA-------------------------NNTYYPRGRGQLTDRGYNHSFMLGRFLKKRYvgtGFLsdfMKPSEMEWRFRAVE .\|.... .\|\|\|\|.\|.\| .. \|...\|\| \| \|.\|\|..\|. ..\|\|..\| \|\|\| \|\|\| ..\|.\|. .\| \|. celkqvqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrY...gfL...ynpdevyvrssdvd RCLATASAVAAGMFKTE---------ERKWLTVPITTNHANQDKLlntPVHSCDIFESAMEKAC--PNLEADNHRDESAIMYECA----GSNHPIFQKIS \|.\|..\| \|..\|\|.\| \| . .. \|\|\| \|... .\| \| \| \|\|. \|. .... . ... .... \| . ... .. . RtlqSaqaflaGlfppeilgsqllnplnvyqpvpietvdsdndtl...pydscpafdellkellasdeflelflerilkllqellpglgltpsdvldlyd IDDSDKYINDYKNNVPVP--D-FICENIEVISEEYMKYRNLKNGIGKpVIIKFRFGVLIDTLLENLKTAWTNNLANKE------------SLKFKVYST . \| ... \| ...\|.\| . \| \| .\|\|... . . . .\|.\| \| \| . \|.\|.. .\|..\|. \|. .. \| . .\|\|. .\|.. lckydtlllgyahglplpfcslfteeelevleyladlefyylygygd.eiaklaggpllneilarledaingdstnlnltldsnpatfpldlklylyfa
0053031	Phosphoglycerate mutase-like	96-338	1.2e-35	116.5	In-house	2-256 (342)	alignment
Range on Protein: 96-338 Range on HMM: 2-256/342.0 RLIFAHTIFRHGSRAPSKNAN-----NTYYPRGRGQLTDRGYNHSFMLGRFLKKRYvgTGFLSDFMKPSEMEWRFRAVERCLATASAVAAGMFKTEERKW .\|.... ..\|\|\|.\|.\| . . ...\|\| \|.\|.\|\|..\|. ...\|\|\|.\|.\|\|\| .\|.\|.. ..\|.\|. .\| \|.\|.\|..\| \|..\|\|.\| \| . eLkqvivlvRHGaRtPlskgpldplnewfypcgageLTplGreqayelGrrlrkrY..lgllpstynpdevyvrssdvdRtlqSAqaflaGlfppegtpi LT-------VPITTNHANQDKLLNTPVHSCDIFESAMEKACPNLEADNHRDES----AIMYECAGSNHPIFQKISIDDSDKYINDYKNNVPVPD----FI \| .\|\| \| ....\| \|\|... ..\|. \|......\|. . \| ... .. . .... \| .. .... .\| \| .. .. .. \|.\|. \| lnpllgwqpipihtepessdalllpnydpcpafdkllkealaseevkellerylellqklskglgltlsdlldlvsdlydlllyelahglplppwctlft CENIEVISEEYMKYRNlKNGIGKPvIIKFRFGVLIDTLLENLKTAWTNnlanKESLKFKVYST \|...........\| . ..\| \| . ..\| ..\|.\|.. .\|..\|. .. . . .\|\|. .\|.. leelkalyaldllyyy.glgpgne.laklaggpllneilarleekisg....pldlklylyfa
0048439	Phosphoglycerate mutase-like	96-338	1.2e-35	116.7	In-house	8-288 (391)	alignment
Range on Protein: 96-338 Range on HMM: 8-288/391.0 RLIFAHTIFRHGSRAPSKNANN----------TYYPRGRGQLTDRGYNHSFMLGRFLKKRYVGTGFLSDFM--KPSEMEWRFRAVERCLATASAVAAGMF .\|.... .\|\|\|\|.\|.\| .. \| ...\| \| \|.\|\|..\|. . \|\|\|.\| \|\|\|\| .\|.\|.. . .\|\|\|. .\| \|.\|.\|..\| \|..\|\|.\| elkqvqvlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqaflaGlf KtE--------------ERKWLTVPITTNHANQDKLLNTPVHSCDIF------ESAMEKACPNLEADNHRD-----------ESAIMYECAGSNHPIFQK . . . .\|\| \| . .\|.\|\| ... ... \| \|...\| \|. . . \|.\|. . . . ..\|... p.plgltvilvivvesedpllnplpintcplledlllldalsalprfylseilerlaevlnrvlglnltaedvlslfdlcaketaalgsllklssplcdl ISIDDSdkYINDYKNNVPVPDFICEN------IEVISEEYMKYRNLKNGIGkpVIIKFRFGVLIDTLLENLktawtnNLANKESLKFKVYST .. \| .. .\| .. \|.\|... .. ...... .. . .. .\| \| .\| \| ..\|.\|....\|..\| . ... ..\|. .\|.. ftlydt..llyeyahglplpewltdellspellkqladlvnelyyyltgsg..eiaklaggpllneilddl......vangpsdpklylyfa
0046349	Phosphoglycerate mutase-like	96-338	1.7e-35	116.0	In-house	6-301 (409)	alignment
Range on Protein: 96-338 Range on HMM: 6-301/409.0 RLIFAHTIFRHGSRAPSKN----ANNTY-----YPRGRGQLTDRGYNHSFMLGRFLKKRYVGTGFLSDF--MKPSEMEWRFRAVERCLATASAVAAGMFK .\|.... .\|\|\|\|.\|.\| \|. \| .. .\|.\| \|\|\|\|..\|.. ..\|\|..\|.\|\|\|\| .\|.\|.. ..\|.\|. .\| \|.\|.\|..\| \|..\|\|.\| eLkqvqvlfRHGaRtPtkklsflpnwpginwtngpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynpdeiyvrssdvdRtlqSAqaflaGlfp TEERKWLTVPITTNH------ANQDKLLNTPVHSCDIFESAMEKACPNLEADNHRDES--AIMYE-----------CAGSNHPIFQKIS---------ID .. .. ....... . \| . ....\| . .....\|\|.\|... .. . . ..\| . . . ....\|.. .. plggeivpllrqdlldppfqpipidtvpiseddalddtllppdslcpaldkllkenlkslsevleflvdealldlelldetkdllkklaerlnselpgln ----------DSDKYINDYKNNVPVPD----FICENIEVISEEYMKYRNLKNGIGkpVIIKFRFGVLIDTLLENLKTAWTNNLANKE--SLKFKVYST \| .. .. .. \| \|. \| \| ..\|... . . .. .\| \| . \| . \|.\|.. .\|..\|. \|.... .. .\|\|. .\|.. ltdpldvasllydtllyetahglplppwcdlftpeelkvlayladleyyylygsg..elaklaggpllneilarledaisgknpvtfpldlklylyfa
0049226	Phosphoglycerate mutase-like	96-338	3.7e-35	114.8	In-house	2-256 (342)	alignment
Range on Protein: 96-338 Range on HMM: 2-256/342.0 RLIFAHTIFRHGSRAPSKNAN-----NTYYPRGRGQLTDRGYNHSFMLGRFLKKRYvgTGFLSDFMKPSEMEWRFRAVERCLATASAVAAGMFKTEERKW .\|.... ..\|\|\|.\|.\| .. . ..... \| \|.\|\|..\|. ..\|\|\|.\|.\|\|\| .\|.\|.. ..\|.\|. .\| \|.\|.\|..\| \|..\|\|.\| \| . . kLkqvqvliRHGdRtPlakgpldflnewfwgcglgeLTplGreqayelGrrlrkrY..lgllpstynpdevyvrssdvdRtlqSaqaflaGlfppeltpi LT-------VPITTNHANQDKLLNTPVHSCDIFESAMEKACPNLEADNHRDE----SAIMYECAGSNHPIFQKISIDDSDKYINDYKNNVPVPDF----I \| .\|\|.\| .. .\| \|\|..\| \|\|. \|...... . . \|.... .\| .... \| \| ..... \| .. .. ...\|.\|.. . lvplldwqpipiitepesndtllllpydscpnfdkllkellkseevqlfleeildllkklskllglnlstlsdvadtlydlllyelahglplppwcslft CENIEVISEEYMKYRNLKNGiGKpVIIKFRFGVLIDTLLENLKTAWTnnlaNKESLKFKVYST \| ..........\| .. . \| \| . . \|.\|.. .\|..\|. \|. .. .\|\|. .\|.. leelkalyaldllyyygigy.ge.eiarlaggpllneilarleeaie....gpsdlklylyfa
0047369	Phosphoglycerate mutase-like	95-338	6.6e-34	110.8	In-house	42-331 (438)	alignment
Range on Protein: 95-338 Range on HMM: 42-331/438.0 RRLIFAHTIFRHGSRAPSKNA-------------------------NNTYYPRGRGQLTDRGYNHSFMLGRFLKKRYvgtGFLsdfmKPSEM-EWRFRAV .\|.... .\|\|\|\|.\|.\|.\|.. \|....\| \| \|\|\|\|..\|. ..\|\|..\| \|\|\| \|.\| \|... .\| \| celkqvqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrY...glL....npedvlyvrssdv ERCLATASAVAAGMFKTEERKWL------TVPITTNHANQDKLLNT-PVHSCDIFESAMEKACP--NLEADNHRDESAIMYECAG-SNHPIFQKISIDDS .\|.\|..\| \|..\|\|.\| \| ...\| ..\|\| \| . ..\| \|\|\|. \| \|\|. \|. .... . ..\| .... . .. .\| .. . ... \| dRtlqSAqaflaGlfppegtgelapilwqpipihtipesddfllnllpsdscpafdellkeflasdeflelllkdilkrlkkllpglnltpsdvldlydl ---DKYINDYKNN--VPVPD-FICENIEVISEEYMKYRNLKNGIGKpVIIKFRFGVLIDTLLENLKTAWTNNLANKE------------SLKFKVYST \| ..\|.\| . .\| .. \| \| .\|\|.. . . ..\|.\|. . \| . \|.\|.. .\|..\|. \|.... \| . .\|\|. .\|.. caydtlangyaglplspfcslftpeelevleyladlefyylygygn.elaklaggpllneilarledaingkstnlnltldsngvtfPldlklylyfa
His_Phos_2	Histidine phosphatase superfamily (branch 2)	97-325	1.8e-19	62.8	Pfam-A	2-284 (347)	alignment
Range on Protein: 97-325 Range on HMM: 2-284/347.0 LIFAHTIFRHGSRAPSKNAN-------------------------NT------YYPRGRGQLTDRGYNHSFMLGRFLKKRYVgtGFLSDFMKPSEMEWRF \| . ....\|\|\| \|.\| .. . .\| .. . \|.\|\| .\| . . \|\|..\|..\|\|. \|.\|.\| ....... \| LkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYp..gllrdhltyedvkirs RAVERCLATASAVAAGMFKTEE----------RKWLTVPITTNHA---NQDKLLNTPVHSCDIFES----AMEKACPNLEADNHRDESAIM----YECAG .\|.\|\|.\| \|.\|\|\|... \|. ... .... \| . ... \|\| . .\|\| \|.. ..... .. . . .. \| \| sserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalctg -SNHPIFQKISIDDSDKYINDYKNNVPVPDFiCENIEVISEEYMKYRNLKN-----GIGKPvIIKFRFGVLIDTLLENLKTAWTNNL .\| .. . . . . ..... ..\|. .... ... ....\|.. \|\|\|.. . . . . \|. \|\|.... . .. ednllfkerweklfreffeeekfdiskipel.ydtmkydalhnrqledleelyklygigde.eklkigllllnpllkkilsdleetq
His_Phos_2	Histidine phosphatase superfamily (branch 2)	97-325	1.8e-19	62.8	In-house	2-284 (347)	alignment
Range on Protein: 97-325 Range on HMM: 2-284/347.0 LIFAHTIFRHGSRAPSKNAN-------------------------NT------YYPRGRGQLTDRGYNHSFMLGRFLKKRYVgtGFLSDFMKPSEMEWRF \| . ....\|\|\| \|.\| .. . .\| .. . \|.\|\| .\| . . \|\|..\|..\|\|. \|.\|.\| ....... \| LkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYp..gllrdhltyedvkirs RAVERCLATASAVAAGMFKTEE----------RKWLTVPITTNHA---NQDKLLNTPVHSCDIFES----AMEKACPNLEADNHRDESAIM----YECAG .\|.\|\|.\| \|.\|\|\|... \|. ... .... \| . ... \|\| . .\|\| \|.. ..... .. . . .. \| \| sserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalctg -SNHPIFQKISIDDSDKYINDYKNNVPVPDFiCENIEVISEEYMKYRNLKN-----GIGKPvIIKFRFGVLIDTLLENLKTAWTNNL .\| .. . . . . ..... ..\|. .... ... ....\|.. \|\|\|.. . . . . \|. \|\|.... . .. ednllfkerweklfreffeeekfdiskipel.ydtmkydalhnrqledleelyklygigde.eklkigllllnpllkkilsdleetq
subfamily_ACP6_pd	Subfamily ACP6	124-337	2.8e-14	44.6	In-house	75-289 (376)	alignment
Range on Protein: 124-337 Range on HMM: 75-289/376.0 RGQLTDRGYNHSFMLGRFLKKRYVG-TGFLSDFMKPSEMEWRFRAVERCLATASAVAAGMFK-TEERKWLTVPITTNHANQDKLLNTpVHSCDIFE---S \|\|\|\| \| . \| \|\|\| \|.\|\|\|\| .\|\|\| .\| \|. \| .\|\| \| \| . \|\|... .\| \| . . \|. .... \|. ..\| . . kGqLtkvGmqqvfdLGrkLrkrYvedikfLsqefnpqevyiRstnieRtlesarclvaGLygkiiiqkelpiilytdeedeevlyPn.rqrcpllsrayr AMEKACPNLEADNHrDESAIMYECAGSNHPIFQKISIDdsDKYINDYKNNVPVPDFICENIEVISEEYM-KYRNLKNGIGKPV--IIKFRFGVLIDTLLE ...\| .\|. . \| . \| . \|.. .. .\|. \|. . \|..\|\|. . . \|..\| . . . . \| .\| .\| \|.\|. \| .....\|\| svrksaislpGise.dtkqiadvldiseekkldfvslr..DniaArlaHnlkvppilkdvidliekhAveelvvlleggdrpekeilklsvGkvlkeile NLKTAWTNNLANkesLKFKVYS \|\|. \| .... \|...\|\| nlekakekeipa...rklrLys
subfamily_HP2-Group1_pd	Subfamily HP2-Group1	124-187	1.2e-09	29.0	In-house	92-155 (422)	alignment
Range on Protein: 124-187 Range on HMM: 92-155/422.0 RGQLTDRGYNHSFMLGRFLKKRYVGTGFLSDFMKPSEMEWRFRAVERCLATASAVAAGMFKTEE .\|\|\| \|\| . \|. \|.\| \|\| \|\|\|\| ...\|\|. \| . \| . .\| \|. \|\|. . vaqltleGykqqelnGqilrkvyvdtGflkssldssevylrsddesrtilsaqalilGmypqdt
subfamily_MINPP1_pd	Subfamily MINPP1	123-233	7.1e-06	17.1	In-house	88-198 (420)	alignment
Range on Protein: 123-233 Range on HMM: 88-198/420.0 GRGQLTDRGYNHSFMLGRFLKKRYVGtgFLSDFMKPSEMEWRFRAVERCLATASAVAAGMFKTEE---RKWLTVPITTNHANQDKLLNtPVHSCDIFESA ..\|. \|.. .\|.. \|..\|. ... ..\| ... . \| .\|.. .\|.\| \| \|...\|.\| . \| ........\|\|\|\| ...\|\|. .... lekslvaqgqeeleelakrlarrfpa..lfeevynpdsfsfastakkRtvksaqaFaeGLsetgevlgdefnivlqeiseqesdklLr.ffdsCkkyknk MEKACPNLEADNHR ..\| \|\|. .. vkknelnlkeeeef

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