Gene pho-12 in Caenorhabditis elegans

Synonym: CELE_C27A2.4, pho-12

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily ACP2
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP141_AA protein Get Run
CeleP141_AA_12-405 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP2_pd Subfamily ACP2 22-404 4.4e-102 334.3 In-house 6-360 (361) alignment 
Range on Protein: 22-404
Range on HMM: 6-360/361.0
GFDLVFVQALWRHGDRAAQYPYKNDQFVEEDWkiiGSGIGQLTYKGVKQQIQLGEAIRQRYIE-SGFLSQGFDPEMIKFRSTNRNRTILSAEANFLGMYP
  .| |||.|.|||||... .|.||.. |..|   ..|.|||| .|..||..||. .|.||.| ..||.. ..|. |..||.. |||. || ... |..|
erkLkfvqvlfRHGdRsPlntypndkykedew...pqglGqLTeeGmqqqyeLGkfLrkrYvedtkfldakynpkqiyvrSsdvnRTlmSaqsvlaglfp

NEGAV---------TLPVTVPdDYSKDCVNNVMCKCQRRSKLQNMAKNLEEYKNIVEHPKVnsLFSKLSEHTGEVINADNFWRIPDTLRCEKQNFPCefE
.|. |         . ||..  ....|.. . ...|.|. .|.. ||. .|.|...|. |   |..||||.||| |. .||....||| ||......   
petgvdypdeqeWqpvPvhtv.seeedlllrakknCprydellqeakespevkklleenke..lleklsestgedidlenfyqlsdtlicerkyane..l

KKTPWYSEGLLDELEVLNTKINRFTSGLYTSKSEngvdvgkEIQKLRSGPLVSEIFERMKNKLDCQVGGGRasrlgcsetvqkMKYYAYSSHDMTLYALL
. ..|... |...|| |..|. ....||...|..       |..|||.|||..|..|.||.||.|.    .            .|...||.|| ||.|||
nlpewandelfekleeladkvkeaefglnnektr.......elkklrgGpllnellenmkeklkceekkkk............lklflYSaHDttlaalL

NALGIEdltsseIGGWPSYASSLFIELLLRqSDRTPYFRVIYRNPSSSNEFlNITPliPNCHGSSFCLLEAFEEIYNKFKIDLpISEYCHVTD
.||||        ...|.|||....||  . .| .|...|.||| .|.... ..|   |.|.|...| |..|..|...|..|  ..| |....
eaLgif......ekkappyasaiivElyee.ddgkplvkvlyrnetskdpp.eltl..pgCkgeedCplskfkkivkpfipdd.vdelCeakt
0046349 Phosphoglycerate mutase-like 22-404 1.3e-69 228.3 In-house 4-394 (409) alignment 
Range on Protein: 22-404
Range on HMM: 4-394/409.0
GFDLVFVQALWRHGDRAAQY---PYKNDQfvEEDWKIIGSGIGQLTYKGVKQQIQLGEAIRQRYIESGFLSQG--FDPEMIKFRSTNRNRTILSAEANFL
|  |..||.|.|||.|.  .    ..|..  .. |.... |.||||..|..|...||...|.||...|.|...  ..|. |..||.. .||. ||.|.. 
gceLkqvqvlfRHGaRtPtkklsflpnwp..ginwtngpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynpdeiyvrssdvdRtlqSAqafla

GMYPNEGA-V--------------TLPVTV----PDDYSKDCVNNVMCKCQRRSKLQNMAKNL-EEYKNIV---------EHPKVNSLFSKLSEHT----
|..|..|  .              ..|. .     ||.  |..... . |..  || . .... .|.....          .... .|..||.|..    
Glfpplggeivpllrqdlldppfqpipidtvpiseddalddtllppdslcpaldkllkenlkslsevleflvdealldlelldetkdllkklaerlnsel

-GEVIN-ADNFWR-IPDTLRCEKQN-FPCEfekktPW---YSEGLLDELEVLNTKINRFTSGLytsksengvdvGkEIQKLRSGPLVSEIFERMKNKLDC
 |  .. .....  . ||| .|. . .|       ||   ... .|. |. |..    .. |            | |. ||..|||..||..|.......
pglnltdpldvasllydtllyetahglplp.....pwcdlftpeelkvlayladleyyylygs...........g.elaklaggpllneilarledaisg

qvgggrasrlgcsE----TVQKMKYYAYSSHDMTLYALLNALGIEDlTSSEIGGWPSYASSLFIELLLRQSDRTPYFRVIYRNPsssneflnitpLIPNC
             .       . |.|.|..|| |..|||.|||. | ..  . ..| |||.|..||.   || ..|.||.|..             .| .
.............knpvtfpldlklylyfaHdttiaallsaLglfd.rlfrssdippyasnlvfElyecpsdgeyyVrvlyngg...........plplp

HGSSFCLLEAFEEIYNKFKIDL---PISEYCHVTD
.....| |. | |...|. ..     . ..|...|
gcgegcplsefkellkkrlpgcgltdfdklCpled
0048439 Phosphoglycerate mutase-like 18-390 2e-68 224.5 In-house 4-389 (391) alignment 
Range on Protein: 18-390
Range on HMM: 4-389/391.0
PsdDGFDLVFVQALWRHGDRAAQYPYKN--DQFVEEDWKIIGSGIGQLTYKGVKQQIQLGEAIRQRYIESGFLSQGF--DPEMIKFRSTNRNRTILSAEA
|  .|  |..||.|.|||.|.. . |.|  |.... .. ... | |.||..|..|...||...|.||...|.|....  .|. ...||.. .||. ||.|
p..agcelkqvqvlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqa

NFLGMYPNE---------------GAVTLPVTVpDDYSKDCVNNVMCKCQRRSKLQNMAKNLEEYKNIV-----EHPKVNSLF---SKLSEHTGEV----
.. |..|..               ..  ||. .  .. .|  .  . .. .| .|... . |.|. | |      . .| |||   .|..  .| .    
flaGlfpplgltvilvivvesedpllnplpint.cplledlllldalsalprfylseilerlaevlnrvlglnltaedvlslfdlcaketaalgsllkls

INADNFWRIPDTLRCEKQN---FPcefekktPWYSEGLLDE--LEVLNTKINRFTSGLYTSKsengvdvgkEIQKLRSGPLVSEIFERMKNKLDcqvggg
 .  ... . ||| .|. .   .|       .|. ..||..  |..|   .|..  .|. |.         ||.||..|||..||....... .      
splcdlftlydtllyeyahglplp.......ewltdellspellkqladlvnelyyyltgsg.........eiaklaggpllneilddlvangp......

rasrlgcsetvQKMKYYAYSSHDMTLYALLNALGIEDLTSSEIGGWPSYASSLFIELLLRQSDRTPYFRVIYRNPSSS----------NEF-LNITPLIP
           .. |.|.|..|| |..|||.|||. ..|     ..| |||.|..||.  .|| ..|.||.|.. . .          .|| | ..  .|
...........sdpklylyfaHdttiaallsaLglfndtlplpadlppyasnlvfElyecpsdgeyyVrvlynggtldlprdltlldldefllrlvlplp

NCHGSS--FCLLEAFEEIYNKF
.|...   .| |..| |...|.
gcgsgpgglCplddFvelvkkr
0048946 Phosphoglycerate mutase-like 13-405 3.3e-68 223.6 In-house 27-414 (447) alignment 
Range on Protein: 13-405
Range on HMM: 27-414/447.0
SSLSLPSD--DGFDLVFVQALWRHGDRAAQYPY--------------------------KNDQFVEEDWKIIGSGIGQLTYKGVKQQIQLGEAIRQRYie
.....|..  .|. |..||.|.|||.|.  ..|                          .... . ...   . | ||||..| .|...||...|.||  
pgygipepvpegcelkqvqvlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkneplwpcglgqLTplGreqlyelGkrlrkrY..

SGFLSqgfDPEMIKFRSTNRNRTILSAEANFLGMYPNE---GAVTLPVTVPDDYSKDCVNNvMCKCQRRSKLQNMAknlEEYKNivehpKVNSLFSKLSE
.|.|.   .|. |..||.. .||. ||.|.. |..|.|   |... |. .....  .  .. .|.    .  ...|   ||.|.       ..|...|..
lgllp...npseiyvrssdvdRtlqSaqaflaGlfppepplgyqpipihtvpssndnlllp.sCpafkellkkela...eelke.....llkellerlkk

HTGEV-INADNFWRIPDTLRCEKQNFpcEFEKKTPWYSEGLLDELEVLNTKINRFTSGLYTsksEngvdvgkeIQKLRSGPLVSEIFERMKNKLDCQVgg
..| . ....... . |.| .|.. .     . ...... .|. || |.  ....  | .    |        ...|..|||..||..|........   
llgglnltlsdvydlydlllyetaih..glsplcslftpeelevleyladlefyyeygygd...e........larlaggpllneilarledaisgds..

grasrlgcsetvqkmKYYAYSSHDMTLYALLNALGIEDLtsseigGW-------------------PsYASSLFIELLLRQS----DRTPYFRVIYrnps
               |.|.|..|| |..|||.|||. |        .                   | |||.|..||.  .|    | ..|.||.|    
...............klylyfaHdttiaallsaLglfdd......elplpadnlpfnrlfrsseivP.yasnlvfElyecpsslpsdgeyyVrvly....

sSNEFLNitplIPNCHGSS--FCLLEAFEEIYNKFkIDlPISEYCHVTDD
 ..| |.    .|.|....  .| |..| |...|| ..  . ..|..|..
.ngeplp....lpgCgsgpgglCplddFkellkkf.lp.dweklCgltls
0049059 Phosphoglycerate mutase-like 16-400 1e-66 218.6 In-house 34-434 (435) alignment 
Range on Protein: 16-400
Range on HMM: 34-434/435.0
SLPSDDGFDLVFVQALWRHGDRAAQY-----------------PYKNDQFVEEDWKIIGSGIGQLTYKGVKQQIQLGEAIRQRYiesGFLsqgFDPEMIK
||.  .|. |..||.|.|||.|.  .                 .| |. . . ..  .  | |.||..|..|...||. .|.||   |||   ..|. ..
sldvpegcelkqvqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrY...gfL...ynpdevy

FRSTNRNRTILSAEANFLGMYPNE----------GAVTLPVTVPDDYSKDCVnnVMCKCQRRSKLQNMAKNLEEYKNIVeHPKVNSLFSKLSEHTGevIN
.||.. .||. ||.|.. |..|.|            ......  .|.  |..   .. |..  .|..  ....|....  .... .|...|....|  ..
vrssdvdRtlqSaqaflaGlfppeilgsqllnplnvyqpvpietvdsdndtl..pydscpafdellkellasdeflelf.lerilkllqellpglg..lt

ADNFWRIPDTLRCEKQNFPCEFEKKTPWYSEGLLDELEVLNTKINRFTSGLYTSKSengvdvgkEIQKLRSGPLVSEIFERMKNKLDCQ-VGGGRASRLG
..... ..|.  .. ...   . .. |..|    .|||||    .  .  ||.  .        || ||..|||..||..|........ ..  .    .
psdvldlydlckydtlllgyahglplpfcslfteeelevleyladlefyylygygd........eiaklaggpllneilarledaingdstnlnltldsn

CSETVQKMKYYAYSSHDMTLYALLNALGI-EDLTSSEIGGW---------------PsYASSLFIELLLRQSDRTPYFRVIYRNpsssneflnITPLIPN
...   . |.|.|..|| |...||.|||. .| .   ....               | |||.|..||.  ... ..|.||.| .          .  .|.
patfpldlklylyfaHdttiapllsaLglfddqlplpadntpfpeldrlfrtseivP.yasnlvfElyecpdgneyyVrvlyng.........kvlplpg

CHGSS--FCLLEAFEEIYNKFkIDLPISEYC
|....  .| |..| |...|| ..    ..|
cgsgpgglCplddFkelvkkf.lpgddfdeC
0047369 Phosphoglycerate mutase-like 16-401 1.5e-66 218.3 In-house 35-437 (438) alignment 
Range on Protein: 16-401
Range on HMM: 35-437/438.0
SLPSDDGFDLVFVQALWRHGDRAA-----------------QYPYKNDQF-VEEDWKiIGSGIGQLTYKGVKQQIQLGEAIRQRYiesGFLsqgfDPEMI
||.  .|. |..||.|.|||.|.                   ..|.....    ||. .  | ||||..|..|...||. .|.||   |.|    .|| .
sldvpegcelkqvqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwl.gpcgagqLTplGreqayelGkrlrkrY...glL....npedv

-KFRSTNRNRTILSAEANFLGMYPNEGA---------VTLPVTVPDDysKDCVNN--VMCKCQRRSKLQNMAKNLEEYKNIVeHPKVNSLFSKLSEHTGe
 ..||.. .||. ||.|.. |..|.||          .   .|.|..   | ..|   .. |.....|..  ....|..... .... ....|| . .. 
lyvrssdvdRtlqSAqaflaGlfppegtgelapilwqpipihtipes..ddfllnllpsdscpafdellkeflasdeflell.lkdilkrlkkllpgln.

vINADNFWRIPDTLRCEKQNFPCEFEKKTPWYSEGLLDELEVLNTKINRFTSGLYTSksengvdvGKEIQKLRSGPLVSEIFERMKNKLDCqvG-GGRAS
 ....... . |..... ... .   .  |..|.   .|||||    .  .  ||..        |.|. ||..|||..||..|.......  .  .  .
.ltpsdvldlydlcaydtlangyaglplspfcslftpeelevleyladlefyylygy........gnelaklaggpllneilarledaing..kstnlnl

RLGCSETVQ--KMKYYAYSSHDMTLYALLNALGIEDLTSSeIGGW-----------------PsYASSLFIELLLRQSDRTPYFRVIYrnpssSNEFLNi
 |.....    . |.|.|..|| |..|||.|||. | |   ..|.                 | |||.|..||.   || ..|.||.|     ... |  
tldsngvtfPldlklylyfaHdttiaallsaLglfddtwp.lpglpldkialnrlfrsseivP.yasnlvfElyecpsdgeyyVrvly.....ngkvlp.

tplIPNCHGSS--FCLLEAFEEIYNKFKIDlPISEYCH
   .|.|....  .| |..| |...|.. .  . |.|.
...lpgcgsgpgglCplddFkelvkkllpg.dfeelCg
0049226 Phosphoglycerate mutase-like 25-400 1.6e-65 214.6 In-house 3-340 (342) alignment 
Range on Protein: 25-400
Range on HMM: 3-340/342.0
LVFVQALWRHGDRAAQYPYKNDQFveeDWKIIGSGIGQLTYKGVKQQIQLGEAIRQRYieSGFLSQGFDPEMIKFRSTNRNRTILSAEANFLGMYPNEGA
|..||.|.|||||.  . ...|..    ..  | |.|.||..|..|...||...|.||   |.|.. ..|. ...||.. .||. ||.| . |..|.|..
LkqvqvliRHGdRtPlakgpldfl...newfwgcglgeLTplGreqayelGrrlrkrY..lgllpstynpdevyvrssdvdRtlqSaqaflaGlfppelt

VT---------LPVTVPDDySKDCVNNV-MCKCQRRSKLQNMAKNLEEYKNIVehPKVNSLFSKLSEHTGEVI-NADNFWR-IPDTLRCEKQNfpceFEK
           .|... .. | | ...  .. | . .||..  .. ||....   ..  .|..|||...|  . .. ...  . |.|..|...      .
pilvplldwqpipiitepe.sndtllllpydscpnfdkllkellkseevqlfl..eeildllkklskllglnlstlsdvadtlydlllyelah....glp

KTPWYSEGLLDELEVLNTKINRFTSGLYTSKsengvdvgkEIQKLRSGPLVSEIFERMKNKLDcqvgggrasrlgcseTVQKMKYYAYSSHDMTLYALLN
  ||.|. .|.||..|   ....  |.. .          ||..|..|||..||..|......               .  . |.|.|..|| |..|||.
lppwcslftleelkalyaldllyyygigyge.........eiarlaggpllneilarleeaie...............gpsdlklylyfahdttiaalls

ALGIEDltsseiGGWPSYASSLFIELLLRQsdRTPYFRVIYRNPSSSNEflnITPLIPNChgSSFCLLEAFEEIYNKFKIDlPISEYC
|||. |      ...| |||.|..||.  .   ..| ||.|.. ..|     .|  .|.|  ...| |..| |...|| ..  . |.|
alglfd......dqlPpyasnlvfElyecd..geyyVrvlynggvlslp...vtlplpgc..dglcpldefkelvkkflpg.dfeelC
0053031 Phosphoglycerate mutase-like 25-400 3.4e-65 213.6 In-house 3-340 (342) alignment 
Range on Protein: 25-400
Range on HMM: 3-340/342.0
LVFVQALWRHGDRAAQYPYKNDQFVEEDWkiiGSGIGQLTYKGVKQQIQLGEAIRQRYieSGFLSQGFDPEMIKFRSTNRNRTILSAEANFLGMYPNEGA
|..|..|.|||.|. .. ...|   |  .   . | |.||..|..|...||...|.||  .|.|.. ..|. ...||.. .||. ||.| . |..|.|| 
LkqvivlvRHGaRtPlskgpldplnewfy...pcgageLTplGreqayelGrrlrkrY..lgllpstynpdevyvrssdvdRtlqSAqaflaGlfppegt

VT---------LPVTvPDDYSKDCVNNV-MCKCQRRSKLQNMAKNLEEYKNIVEhpKVNSLFSKLSEHTGevINADN----FWRIPDTLRCEKQNFPcef
           .|.    . | | ...  .. | . .||.. |...||.|.. |  .. .|..|||...|  .....    .. . |.| .|...     
pilnpllgwqpipih.tepessdalllpnydpcpafdkllkealaseevkelle..rylellqklskglg..ltlsdlldlvsdlydlllyelahgl...

eKKTPWYSEGLLDELEVLNTKINRFTSGLYTSksengvdvgKEIQKLRSGPLVSEIFERMKNKLDCqvgggrasrlgcsetVQKMKYYAYSSHDMTLYAL
 .  ||... .|.||..|.  ....  ||. .          |. ||..|||..||..|...|. .                 . |.|.|..|| |..||
.plppwctlftleelkalyaldllyyyglgpg.........nelaklaggpllneilarleekisg...............pldlklylyfahdttiaal

LNALGIEdltsseIGGWPSYASSLFIELLLRQsdRTPYFRVIYRNPSSSnEFLNITplIPNCHGssFCLLEAFEEIYNKFKIDlPISEYC
|.|||.        ...| |||.|..||.  .   ..|.||.|.. . | |.| ..  .|.|.|  .| |..| |...|....  . ..|
lsaLglf......ddqlPpyasnlvfElyedp..geyyVrvlynggtls.eplvlp..lpgcdg..lcplsefkelvkkllpg.dfeklC
His_Phos_2 Histidine phosphatase superfamily (branch 2) 25-353 7.5e-42 136.4 Pfam-A 2-346 (347) alignment 
Range on Protein: 25-353
Range on HMM: 2-346/347.0
LVFVQALWRHGDRAAQYPYK---------------NDQFVEEDWK--------IIGSGIGQLTYKGVKQQIQLGEAIRQRYIesGFLSQGFDPEMIKFRS
| .|....|||||.    .|               |..  . ..             . |.|| .| ||. .||| .||||   |.|.  ...| .|.||
LkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYp..gllrdhltyedvkirs

TNRNRTILSAEANFLGMYPNEG------------AVTLPVTVPDD---YSKDCVNNVMCKCQRRSK----LQNMAKNLEEYKNIVEHPKVNslfSKLSEH
.. .|.. ||.|.. |....||              . .. . |.     |..     ..| .  .    ... ...| .. . |......   ..||. 
sserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenla...krlsal

-TGE-VINADNFWRIPDTLRCEKQnfPCEFEKKTPWYSEGllDELEVLNTKINRFTSgLYTSksengVDVGKEIQKLRSGPLVSEIFERMKNKLDCQVgg
 |||  ..... |.  ..  .|..    .  |   .|..    .    | ......  ||          |.|... . ..|. .........|...   
ctgednllfkerweklfreffeee..kfdiskipelydtm..kydalhnrqledlee.lykl.....ygigdeeklkigllllnpllkkilsdleetq..

grasrlgcseTVQKMKYYAYSSHDMTLYALLNALGIEDLTSSEIGGWPSYASSLFIELLLRqSDRTPYFRVIY
            .. |...|..|| ..|.||||||.|. .. |  ... |||....||.   |....| |...
..........psrhaklrlyfthDshiytllnaLgleekiareaspelpyasqivfelyed.sekkfyvrllf
His_Phos_2 Histidine phosphatase superfamily (branch 2) 25-353 7.5e-42 136.4 In-house 2-346 (347) alignment 
Range on Protein: 25-353
Range on HMM: 2-346/347.0
LVFVQALWRHGDRAAQYPYK---------------NDQFVEEDWK--------IIGSGIGQLTYKGVKQQIQLGEAIRQRYIesGFLSQGFDPEMIKFRS
| .|....|||||.    .|               |..  . ..             . |.|| .| ||. .||| .||||   |.|.  ...| .|.||
LkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYp..gllrdhltyedvkirs

TNRNRTILSAEANFLGMYPNEG------------AVTLPVTVPDD---YSKDCVNNVMCKCQRRSK----LQNMAKNLEEYKNIVEHPKVNslfSKLSEH
.. .|.. ||.|.. |....||              . .. . |.     |..     ..| .  .    ... ...| .. . |......   ..||. 
sserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenla...krlsal

-TGE-VINADNFWRIPDTLRCEKQnfPCEFEKKTPWYSEGllDELEVLNTKINRFTSgLYTSksengVDVGKEIQKLRSGPLVSEIFERMKNKLDCQVgg
 |||  ..... |.  ..  .|..    .  |   .|..    .    | ......  ||          |.|... . ..|. .........|...   
ctgednllfkerweklfreffeee..kfdiskipelydtm..kydalhnrqledlee.lykl.....ygigdeeklkigllllnpllkkilsdleetq..

grasrlgcseTVQKMKYYAYSSHDMTLYALLNALGIEDLTSSEIGGWPSYASSLFIELLLRqSDRTPYFRVIY
            .. |...|..|| ..|.||||||.|. .. |  ... |||....||.   |....| |...
..........psrhaklrlyfthDshiytllnaLgleekiareaspelpyasqivfelyed.sekkfyvrllf
subfamily_PXYLP1_pd Subfamily PXYLP1 60-354 3.1e-21 67.1 In-house 103-367 (419) alignment 
Range on Protein: 60-354
Range on HMM: 103-367/419.0
IGQLTYKGVKQQIQLGEAIRQRYIES-GFL--SQGFDPEMIKFRSTNRNRTILSAEANFLGMYPNEGAVTLPVTVPDDySKDCVNnvMCKCQrrsKLQNM
.||||.||| | ...|. .|. | .. ..|   . .  . . . .|...||. || | . |..|..   .. |    .  . |..  .|.|     |.. 
lgqLtqkGvvqhLevGdllrkvYakklklLlkpnelssDevvlettrkrrtlqsalallygllpkaklkairvresps.vafClg..eCsCP...allrk

AKNLEEYKNIVEHPKVNSLFSKLSEHTGEVI------NADNFWRIPDTLRCEKQNFPCEFekktpwysEGLLDELEVLNTkiNRFTSGlyTSKSENGVDV
 .. |. |. .   ||  .   ..|    .|       . |   .  |. |    .||.         || ..  .|      ...     |.....   
rlekeadkqlLlrgkvldvmksvgetlkgtilqttlngisnpvdalltvlChnvslPcrr........eGcvepshvdvl..hklade..lsqrsakksy

GKEIQKLRSGPLVSEIFERMKNKLDcqvggGrasrlgcsetVQKMKYYAYSSHDMTLYALLNALGIedltssEIGGWPSYASSLFIELLLRQSDRTPYFR
 |   .||. ||. .| .||.   .     |          |.| |.  ||.||.||  |..|||.      . .... ||| |  ||  |....  |.|
yklsGllraypllrdivsrmlkiie.....G..........vdkekfvlysghDvtlrplvaaLgl......seartiayasrlvfelyrreaskeyylr

VIYR
|.| 
vlyn
subfamily_HP2-Group1_pd Subfamily HP2-Group1 59-143 1.9e-16 51.4 In-house 91-175 (422) alignment 
Range on Protein: 59-143
Range on HMM: 91-175/422.0
GIGQLTYKGVKQQIQLGEAIRQRYIESGFLSQGFDPEMIKFRSTNRNRTILSAEANFLGMYPNEGAVTLPVTVPDDYSKDCVNNV
 ..||| .| |||   |...|. |...|||   .|.  . .|| . .||||||.| .|||||... .     | | |..| . . 
avaqltleGykqqelnGqilrkvyvdtGflkssldssevylrsddesrtilsaqalilGmypqdtkaedraqvvdlytrdklfds
subfamily_ACP6_pd Subfamily ACP6 45-148 3e-16 51.1 In-house 60-166 (376) alignment 
Range on Protein: 45-148
Range on HMM: 60-166/376.0
NDQFVEEDWKIIGSGIGQLTYKGVKQQIQLGEAIRQRYIES-GFLSQGFDPEMIKFRSTNRNRTILSAEANFLGMYPNEGA-VTLPVT-VPDDYSKDCVN
 ..  ... .  |   ||||  | .|  .||. .|.||.|  .|||| | |. .  |||| .||. ||.    |.| .. .   ||.    |.  .. . 
ieekykkeilkGGafkGqLtkvGmqqvfdLGrkLrkrYvedikfLsqefnpqevyiRstnieRtlesarclvaGLygkiiiqkelpiilytdeedeevly

NVMCKCQ
  . .|.
Pnrqrcp
subfamily_ACP6_pd Subfamily ACP6 247-357 3.7e-11 34.3 In-house 249-338 (376) alignment 
Range on Protein: 247-357
Range on HMM: 249-338/376.0
GVDVGKEIQKLRSGPLVSEIFERMKNKLDCQVGGgrasrlgcsetvqkMKYYAYSSHDMTLYALLNALGIEDltsseiGGWPSYASSLFIELLLRqSDRT
|   .||| ||  |... || |..... . ..                 | . || || || .|| |||. |      . || .|... .||     .. 
gdrpekeilklsvGkvlkeilenlekakekeipa..............rklrLysaHDttlmtLLlalgvFD......dkWPpfaadvileLyed.kage

PYFRVIYRNPS
 . ||.|..  
yfvrvlYqeke
subfamily_HP2-Group1_pd Subfamily HP2-Group1 295-402 4e-08 24.0 In-house 323-418 (422) alignment 
Range on Protein: 295-402
Range on HMM: 323-418/422.0
MKYYAYSSHDMTLYALLNALGIEDltsseiGGWPSYASSLFIELLLRQSDR---TPYF--RVIYrnpsssNEFLNItplIPNCHGSSfCLLEAFEEIYNK
 |.  || || ||  || ||....      . || ||| |..|||   .     || .  ||.|      |  |     .| |..   | .| ||.  . 
rkfllysGhdttliqllsalnvde......fkwppyasllllellevstapaastpqyavrvly......nGklkk...lpfcdane.csyeqfeaylst

FKIDLPISEyCHV
   . .  . |.|
viphddaed.ckv
subfamily_MINPP1_pd Subfamily MINPP1 61-316 6.9e-07 20.4 In-house 90-325 (420) alignment 
Range on Protein: 61-316
Range on HMM: 90-325/420.0
GQLTYKGVKQQIQLGEAIRQRYIEsgFLSQGFDPEMIKFRSTNRNRTILSAEANFLGMYPNEGAVTLPVTVPDD----YSKDCVNNVMCKCQR-RSKLQN
..|. .| ..  .|.. . .|. .  ...    |. ..|.||...||. ||.|   |. ...  ..  .. .       ..| .  .. .|..  .|...
kslvaqgqeeleelakrlarrfpa..lfeevynpdsfsfastakkRtvksaqaFaeGLsetgevlgdefnivlqeiseqesdklLrffdsCkkyknkvkk

MAKNLEEYKNIVEHPKVNSLFSKLSEHTgevINADNFWRIpDTLRCEKQNFPCEFEK-----KTPWYSEglldeLEVLNTKINRFTSGLYTSKSengVDV
 . ||.| ... | .....  .. .. .    .  ... .      |.    | .|      ...|.|      .|  . .  .. . | .         
nelnlkeeeefleskelqkaleeiakrl...neekkllel.tekdiedmfeiCayelaikgisnvWcsl.....fekdelleleYledLknyyk...egy

GKEIQKLRSGPLVSEIFERMKNKLDCQVGGGRasrlgcsetvqkmkyyAYSSHDMTLYALLNALGI
| || .  | ||. .|.. .|.    ..  .                  .  |. ||  || .||.
GyeinysiscpLlndivkllksseeqkqksss................lrFaHaetllpllsllGl
NDUFB10 NADH-ubiquinone oxidoreductase subunit 10 190-255 9.7e-06 12.2 Pfam-A 26-90 (128) alignment 
Range on Protein: 190-255
Range on HMM: 26-90/128.0
DNFWRIPDTLRCEKQNFPCEFEKKTPWYSEGLLDElEVLNTKINRFTSGLYTSKSENGVDVGKEIQ
 .| |.|.  .|..... | .| .. .  . ..|. |....  .|. .     | .      |...
rkfrrvPeideCqeddvvClyeaeeqyrrdrkvdq.eivkilrerleaCqqyekedhvqkCaklle