Gene pho-7 in Caenorhabditis elegans

Synonym: CELE_T21B6.2, pho-7

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily ACP2
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP147_AA protein Get Run
CeleP147_AA_8-362 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP2_pd Subfamily ACP2 15-361 1.1e-89 293.5 In-house 5-358 (361) alignment 
Range on Protein: 15-361
Range on HMM: 5-358/361.0
CAAEIEFLLAVWRHGDRAPENlPYPSDPHNETFWPRGWNQLTNVGIDQATKLGKFLRRRY-Q-GSVLPV-FDRKKISIRSSDADRAIETAQSVATALFPP
. ....|  ...|||||.|.| .|| |...|. ||.|. |||. |..|...||||||.|| .  . |.  ...|.| .||||..|....||||...||||
eerkLkfvqvlfRHGdRsPln.typndkykedewpqglGqLTeeGmqqqyeLGkfLrkrYvedtkfldakynpkqiyvrSsdvnRTlmSaqsvlaglfpp

DGLQVWNEEKfrFWQPIPIRT-NGKPDPMLRpSKIQCPAYQRIVAEERKK-IESEINVKYKRELEIISNHTSHQTKYGNIKDVYNVIL---EHYNGLPFP
.. . ...|.   |||.|. | ... |..|| .| .||.|. ...| ...    ... ..|  || .|..|.....  |. .... ..   ...| |..|
etgvdypdeq..eWqpvPvhtvseeedlllr.akknCprydellqeakespevkklleenkelleklsestgedidlenfyqlsdtlicerkyanelnlp

NWIDEKVnGKSLLDTIAEIRRIARlQLF--NSRAKAKFMAGYLINSWTESLVLASQ---HISPKKALLYSSHDGTLSALMYGLGISNHQLIPYTACIMIE
.|.....  . |  . ......   .|.  ..| ..|...|.|.| ..|..  ...   . . .| .|||.|| || ||.  ||| ...  ||...|..|
ewandel.fekleeladkvkeaef.glnnektrelkklrgGpllnellenmkeklkceekkkklklflYSaHDttlaalLeaLgifekkappyasaiivE

LHT----GNNVKIYFRNTTTENPDDVHEmfvPGC--STDCHLSKFIKSVNGVRVKSlehLEDICES
|.      ..||...||.|...| ...    |||  ..||.||||.| |. .....   ... || 
lyeeddgkplvkvlyrnetskdppeltl...pgCkgeedCplskfkkivkpfipdd...vdelCea
0049226 Phosphoglycerate mutase-like 18-353 1.1e-64 211.7 In-house 2-337 (342) alignment 
Range on Protein: 18-353
Range on HMM: 2-337/342.0
EIEFLLAVWRHGDRAPENlPYPSDPHNETFWPRGWNQLTNVGIDQATKLGKFLRRRYQGSVLPVFDRKKISIRSSDADRAIETAQSVATALFPPDGLQVW
..... ...|||||.| .  .| |..||.||. |...||..|. || .||..||.||.| . . ...... .|||| ||....||... .||||.. ...
kLkqvqvliRHGdRtPla.kgpldflnewfwgcglgeLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSaqaflaGlfppeltpil

NEEKFrfWQPIPIRT-NGKPDPMLRPSKIQCPAYQRIVAEERK-KIESEINVKYKRELEIISNHTSHQTKygNIKDVYN-----VILEHYNGLPFPNWID
. .    |||||| | . . |..|.... .||...... |  | .  .... ...  |. .|...    .  ...||..     .. | ..|||.|.|..
vplld..wqpipiitepesndtllllpydscpnfdkllkellkseevqlfleeildllkklskllglnls..tlsdvadtlydlllyelahglplppwcs

EkvngksllDTI------AEIRRIARLQLFNSRAKAKFMAGYLINSWTESLVLASQHISPKKALLYSSHDGTLSALMYGLGISNHQLIPYTACIMIELHT
.        .|.      ...       .....  |. ..|.|.| . . |  | .  |. |  ||..||.|. ||.  ||. ..|| || .....||..
l........ftleelkalyaldllyyygigygeeiarlaggpllneilarleeaiegpsdlklylyfahdttiaallsalglfddqlPpyasnlvfElye

GNN---VKIYFRNTTTENPddvHEMFVPGCSTDCHLSKFIKSVNGVRVKSLE
 ..   |...... ... |   ... .|||.. | |..|.. |. ..... |
cdgeyyVrvlynggvlslp...vtlplpgcdglcpldefkelvkkflpgdfe
0048439 Phosphoglycerate mutase-like 14-346 3.4e-64 210.5 In-house 4-388 (391) alignment 
Range on Protein: 14-346
Range on HMM: 4-388/391.0
PCAAEIEFLLAVWRHGDRAPE-NLPYPSDPHNETFW---PRGWNQLTNVGIDQATKLGKFLRRRY-QGSVLP---VFDRKKISIRSSDADRAIETAQSVA
|  .|.... ...|||.|.|  ..|.. ||. . ..   | |...||..|..|. .||..||.|| ... ||   ....... .|||| ||....||...
pagcelkqvqvlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqafl

TALFPPDGLQVWNEEKFRF----WQPIPIRTNGKPDPMLRPSKIQCPAYQrIVAEERKKIESEIN--VKY--------------KRELEIISNHTSHQTK
 .|||| ||.|..   ..     ..|.||.|  ... .|... .... .  .  |. .... ..|  ...              . |. .  . ..  . 
aGlfpplgltvilvivvesedpllnplpintcplledlllldalsalprf.ylseilerlaevlnrvlglnltaedvlslfdlcaketaalgsllklssp

YGNIKDVY-NVILEHYNGLPFPNWIDEKVNGKSLLDTIAEIRRIARLQLFNSRAKAKFMAGYLINSWTESLvlASQHISPKKALLYSSHDGTLSALMYGL
. .. ..| ....| ..|||.|.|. ...  ..||...|..       |..|   || ..|.|.|   . |  . .. |. |  ||..||.|. ||.  |
lcdlftlydtllyeyahglplpewltdellspellkqladlvnelyyyltgsgeiaklaggpllneilddl..vangpsdpklylyfaHdttiaallsaL

GISNH------QLIPYTACIMIELHTGN-----NVKIYFRNTTTENPDDVH-----------EMFVPGCSTD----CHLSKFIKSVNG
|. |.      .|.|| .....||.. .      |...... |.. |.|..            ...|||...    | |..|.. |. 
glfndtlplpadlppyasnlvfElyecpsdgeyyVrvlynggtldlprdltlldldefllrlvlplpgcgsgpgglCplddFvelvkk
0047369 Phosphoglycerate mutase-like 13-353 1.7e-62 204.9 In-house 38-433 (438) alignment 
Range on Protein: 13-353
Range on HMM: 38-433/438.0
LPCAAEIEFLLAVWRHGDRAP----------------ENLPYPSDPHNETF---WPRGWNQLTNVGIDQATKLGKFLRRRYqgSVLpvfDRKKI-SIRSS
.|  .|.... ...|||.|.|                .. .|||.|..      .| |..|||..|..|| .|||.||.||  . |   .....  .|||
vpegcelkqvqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrY..glL...npedvlyvrss

DADRAIETAQSVATALFPPDGLQVWNEekfRFWQPIPIRTNGKPDPMLRP--SKIQCPAYQRIVAeERKKIESEINVKYKRELEIISNHTS-HQTKYGNI
| ||....||...  ||||.| .....    .|||||| |  . | .| .  .  .|||.. ..  |..  .. .....|. |........  .  . ..
dvdRtlqSAqaflaGlfppegtgelap...ilwqpipihtipesddfllnllpsdscpafdellk.eflasdeflelllkdilkrlkkllpglnltpsdv

KDV-----YNVILEHYNGLPFPNWIDekVNGKSLLDTIAEIRRIARLQLF-NSRAKAKFMAGYLINSWTESLVLASQHIS----------------PKKA
 |.     |. .  .|.||| .....  .  ...|.... .  .   .|. ...  || ..|.|.|   . |  | .. |                . | 
ldlydlcaydtlangyaglplspfcs..lftpeelevleyladlefyylygygnelaklaggpllneilarledaingkstnlnltldsngvtfPldlkl

LLYSSHDGTLSALMYGLGISNHQLI---------------------PYTACIMIELHTGN-----NVKIYFrnttteNPddvHEMFVPGCSTD----CHL
 ||..||.|. ||.  ||.......                     || .....||.. .      |....      |.   ... .|||...    | |
ylyfaHdttiaallsaLglfddtwplpglpldkialnrlfrsseivPyasnlvfElyecpsdgeyyVrvly......ng...kvlplpgcgsgpgglCpl

SKFIKSVNGVRVKSLE
..|.. |. ..... |
ddFkelvkkllpgdfe
0048946 Phosphoglycerate mutase-like 9-362 6.9e-62 202.8 In-house 31-412 (447) alignment 
Range on Protein: 9-362
Range on HMM: 31-412/447.0
CSLLLPCAAEIEFLLAVWRHGDRAPE-----------------------------NlPYPSDPHNETFWPRGWNQLTNVGIDQATKLGKFLRRRYqGSVL
..  .|. .|.... ...|||.|.|                              |  .. ...||..|| |..|||..|..|. .|||.||.|| .. |
ipepvpegcelkqvqvlfRHGaRtPtkkylkgleplldllknanvlelggdlsfln.dwkyqlkneplwpcglgqLTplGreqlyelGkrlrkrY.lgll

PvfDRKKISIRSSDADRAIETAQSVATALFPPDglqvwneeKFRFWQPIPIRT-NGKPDPMLRPskiQCPAYQRIVAEERKkieSEINVKYKRELEIISN
|  ....| .|||| ||....||... .||||.            .||||| |  .  |. |.|   .|||.. .. .| .   .|... .|. || ...
p..npseiyvrssdvdRtlqSaqaflaGlfppe........pplgyqpipihtvpssndnlllp...sCpafkellkkela...eelkellkellerlkk

HTSHQT-KYGNIKDVYNVIL---EHYNGLPFPNWIDEkvngkSLLDTIAEIRRIARLQLF-NSRAKAKFMAGYLINSWTESLVLASQHISpkKALLYSSH
...  .  . .. |.|...|    ...  |.......     ..|......  .   ... ...  |. ..|.|.|   . |  | .  |  |  ||..|
llgglnltlsdvydlydlllyetaihglsplcslftp.....eelevleyladlefyyeygygdelarlaggpllneilarledaisgds..klylyfaH

DGTLSALMYGLGISNHQLI------------------PYTACIMIELHTGNN---------VKIYFRNTTTEnpddvhemfVPGCSTD----CHLSKFIK
|.|. ||.  ||.....|                   || .....||.. ..         |.... ...           .|||...    | |..|..
dttiaallsaLglfddelplpadnlpfnrlfrsseivPyasnlvfElyecpsslpsdgeyyVrvlyngeplp.........lpgCgsgpgglCplddFke

SVNGVrVKsleHLEDICESA
 .. . ..   . |. |.. 
llkkf.lp...dweklCglt
0053031 Phosphoglycerate mutase-like 18-352 8.5e-62 202.4 In-house 2-336 (342) alignment 
Range on Protein: 18-352
Range on HMM: 2-336/342.0
EIEFLLAVWRHGDRAPENLpYPSDPHNETFWPRGWNQLTNVGIDQATKLGKFLRRRYQGSVLPVFDRKKISIRSSDADRAIETAQSVATALFPPDGLQVW
|.... ...|||.|.|..  .| ||.||.|.| |...||..|..|| .||..||.||.| . . ...... .|||| ||....||... .||||.| ...
eLkqvivlvRHGaRtPlsk.gpldplnewfypcgageLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSAqaflaGlfppegtpil

NEekFRFWQPIPIRT-NGKPDPMLRPSKIQCPAYQRIVAEERK-KIESEINVKYKRELEIISNHTShqTKYGN----IKDVY-NVILEHYNGLPFPNWID
|   .  |||||| | .  .|..|.|... |||......|  . .  .|.. .|.  |. .|...   ... .    . |.| ... | ..|||.|.|..
np..llgwqpipihtepessdalllpnydpcpafdkllkealaseevkellerylellqklskglg..ltlsdlldlvsdlydlllyelahglplppwct

EKVNGKSLLDtiAEIRRIARLQLFNSRAKAKFMAGYLINSWTESLVLASQHISPKKALLYSSHDGTLSALMYGLGISNHQLIPYTACIMIELHTGNN---
.    . .    ...      .|....  || ..|.|.| . . |  . .. .. |  ||..||.|. ||.  ||. ..|| || .....||.. ..   
lftleelkal..yaldllyyyglgpgnelaklaggpllneilarleekisgpldlklylyfahdttiaallsaLglfddqlPpyasnlvfElyedpgeyy

VKIYFRNTTTENPDDVHemfVPGCSTDCHLSKFIKSVNGVRVKSL
|...... |...| ...   .|||.  | ||.|.. |. ..... 
Vrvlynggtlseplvlp...lpgcdglcplsefkelvkkllpgdf
0049059 Phosphoglycerate mutase-like 10-350 1e-61 202.2 In-house 34-428 (435) alignment 
Range on Protein: 10-350
Range on HMM: 34-428/435.0
SLLLPCAAEIEFLLAVWRHGDRAPE----------------NLPYPSDPH---NETFWPRGWNQLTNVGIDQATKLGKFLRRRYqgSVLpvFDRKKISIR
|| .|. .|.... ...|||.|.|                 .|.||..|.   |....| |...||..|..|| .|||.||.||  . |  ...... .|
sldvpegcelkqvqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrY..gfL..ynpdevyvr

SSDADRAIETAQSVATALFPPDGLQVWNEEKFRFWQPIPIRTNGKPDPMLrpSKIQCPAYQRIVAeERKKIESEINVKYKRELEIISNHTSHqTKyGNIK
||| ||....||... .||||. | .. ....  .||.||.|.   .. |  .  .|||.. ..  | .. .  ... ..| |..... ... ..  ...
ssdvdRtlqSaqaflaGlfppeilgsqllnplnvyqpvpietvdsdndtl..pydscpafdellk.ellasdeflelflerilkllqellpg.lg.ltps

DV---YNV------ILEHYNGLPFP--NWIdekvnGKSLLDTIAEIRRIARLQLFN-SRAKAKFMAGYLINSWTESLVLASQHIS---------------
||   |..      .|....|||.|  ...      ...|......  .   .|.. ..  || ..|.|.|   . |  | .. |               
dvldlydlckydtlllgyahglplpfcslf.....teeelevleyladlefyylygygdeiaklaggpllneilarledaingdstnlnltldsnpatfp

-PKKALLYSSHDGTLSALMYGLGISNHQLI---------------------PYTACIMIELHTGNN-----VKIYFRNtttenpddvHEMFVPGCSTD--
 . |  ||..||.|. .|.  ||. ..||                      ||......||.. ..     |.... .         ... .|||...  
ldlklylyfaHdttiapllsaLglfddqlplpadntpfpeldrlfrtseivPyasnlvfElyecpdgneyyVrvlyng.........kvlplpgcgsgpg

--CHLSKFIKSVNGVRVK
  | |..|.. |. .. .
glCplddFkelvkkflpg
0046349 Phosphoglycerate mutase-like 14-351 3.7e-61 200.5 In-house 3-385 (409) alignment 
Range on Protein: 14-351
Range on HMM: 3-385/409.0
PcAAEIEFLLAVWRHGDRAP---ENLPYPSDPHNETFWPRGWNQLTNVGIDQATKLGKFLRRRY--QGSVLPV--FDRKKISIRSSDADRAIETAQSVAT
|  .|.... ...|||.|.|    ..  . ...| |..|.|. |||..|..|| .|||.||.||  .| . .   .....| .|||| ||....||... 
P.gceLkqvqvlfRHGaRtPtkklsflpnwpginwtngpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynpdeiyvrssdvdRtlqSAqafla

ALFPPDGLQVW----NEEKFRFWQPIPIRTNGKP-----DPMLRPSKIQCPAYQRIVAEERKKIESE-------------INVKYKRELEIISNHTSHQT
.||||.| ...     . .  ..||||| |   .     | .| |..  |||......|  | ..               .. ..|. |. .....  . 
Glfpplggeivpllrqdlldppfqpipidtvpiseddalddtllppdslcpaldkllkenlkslsevleflvdealldlelldetkdllkklaerlnsel

KYGNI---KDVYN-----VILEHYNGLPFPNWIDEkvNGKSLLDTIAEIRRIARLQLFNSRAKAKFMAGYLINSWTESLVLASQHIS------PKKALLY
.  |.   .||..      . | ..|||.|.| |     ...|...|.. ..    |..|.  || ..|.|.| . . |  | .. .      . |  ||
pglnltdpldvasllydtllyetahglplppwcdl..ftpeelkvlayladleyyylygsgelaklaggpllneilarledaisgknpvtfpldlklyly

SSHDGTLSALMYGLGISN-----HQLIPYTACIMIELHTG--NN---VKIYFRNTttenpddvhEMFVPGCSTDCHLSKFIKSVNGVRVK----S
..||.|. ||.  ||...     ....|| .....||..   ..   |......          .. .|||.. | ||.|.. .. ....    .
faHdttiaallsaLglfdrlfrssdippyasnlvfElyecpsdgeyyVrvlyngg.........plplpgcgegcplsefkellkkrlpgcgltd
His_Phos_2 Histidine phosphatase superfamily (branch 2) 18-312 7.2e-39 126.6 Pfam-A 1-346 (347) alignment 
Range on Protein: 18-312
Range on HMM: 1-346/347.0
EIEFLLAVWRHGDRAP-------------------ENLPYPSDPHN------ETFWPRGWNQLTNVGIDQATKLGKFLRRRYQGSVLPVFDRKKISIRSS
|.... .|.|||||.|                   .| . . .         .  .. .| .||. |  || .||..||.||.| . . ...... ||||
eLkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYpgllrdhltyedvkirss

DADRAIETAQSVATALFPPDG-LQVWNEEKFRFWQPIPIRTNGK----PDPMLRPSKIQCPAYQRIVAEERKKIESEINVKYKRELEIIS-------NHT
. .| ...||..| .|..|.| | . . .. . .......|  .     ...||. . .|||..  ...  |. . ..|   | . | ..       .  
serRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalctge

SHQTKYGNIKDVYNVILEHY--NGLPFPNWIDEKvngKSLLDTIAEIRRIAR-LQL-FNSRAKAKFMAGYLINSWTESLVLASQHIS---PKKALLYSSH
.. .   . ... .   |.   .....|.. |..   |  . .......  .  .|   ..  .. ... |.|   . .. . ..      .| .||..|
dnllfkerweklfreffeeekfdiskipelydtm...kydalhnrqledleelyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfth

DGTLSALMYGLGISN------HQLIPYTACIMIELHT-GNN---VKIYF
| .. .|.  ||...      .. .|| ..|..||.   ..   |...|
DshiytllnaLgleekiareaspelpyasqivfelyedsekkfyvrllf
His_Phos_2 Histidine phosphatase superfamily (branch 2) 18-312 7.2e-39 126.6 In-house 1-346 (347) alignment 
Range on Protein: 18-312
Range on HMM: 1-346/347.0
EIEFLLAVWRHGDRAP-------------------ENLPYPSDPHN------ETFWPRGWNQLTNVGIDQATKLGKFLRRRYQGSVLPVFDRKKISIRSS
|.... .|.|||||.|                   .| . . .         .  .. .| .||. |  || .||..||.||.| . . ...... ||||
eLkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYpgllrdhltyedvkirss

DADRAIETAQSVATALFPPDG-LQVWNEEKFRFWQPIPIRTNGK----PDPMLRPSKIQCPAYQRIVAEERKKIESEINVKYKRELEIIS-------NHT
. .| ...||..| .|..|.| | . . .. . .......|  .     ...||. . .|||..  ...  |. . ..|   | . | ..       .  
serRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalctge

SHQTKYGNIKDVYNVILEHY--NGLPFPNWIDEKvngKSLLDTIAEIRRIAR-LQL-FNSRAKAKFMAGYLINSWTESLVLASQHIS---PKKALLYSSH
.. .   . ... .   |.   .....|.. |..   |  . .......  .  .|   ..  .. ... |.|   . .. . ..      .| .||..|
dnllfkerweklfreffeeekfdiskipelydtm...kydalhnrqledleelyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfth

DGTLSALMYGLGISN------HQLIPYTACIMIELHT-GNN---VKIYF
| .. .|.  ||...      .. .|| ..|..||.   ..   |...|
DshiytllnaLgleekiareaspelpyasqivfelyedsekkfyvrllf
subfamily_ACP6_pd Subfamily ACP6 54-318 6.9e-23 72.9 In-house 77-336 (376) alignment 
Range on Protein: 54-318
Range on HMM: 77-336/376.0
QLTNVGIDQATKLGKFLRRRYQGSV---LPVFDRKKISIRSSDADRAIETAQSVATALFppdglqvwNEEKFRFWQPIPIRTNGKPDPMLRPSKIQCPAY
|||.||  |. .||. ||.||   .    ..|  ... ||| . .|..| |. . . |.        .... .   || . |... . .| |.. .||  
qLtkvGmqqvfdLGrkLrkrYvedikfLsqefnpqevyiRstnieRtlesarclvaGLy........gkiiiqkelpiilytdeedeevlyPnrqrcpll

QRIVAEERKKI-----ESEINVKYKRELEIISNhtsHQTKYGNIKDVYNVILEHynGLPFPNWIDEKVngkSLLDTIAeIRRIARLQLFNSR---AKAKF
.|.. . ||.       ||   . ...|.| ..   .. ..  ..|.    |.|  .|. |. . . .    |..  | .. .  |.  . |      |.
srayrsvrksaislpGisedtkqiadvldisee...kkldfvslrDniaArlaH..nlkvppilkdvi...dliekhA.veelvvlleggdrpekeilkl

MAGYLINSWTESLVLASQHISP-KKALLYSSHDGTLSALMYGLGISNHQLIPYTACIMIELHTGNNVKIYFRNTTTE
 .| ...  .| |  | ....| .|  ||| || ||..|.  ||. ...  |..| ...||.  .. . . |   .|
svGkvlkeilenlekakekeiparklrLysaHDttlmtLLlalgvFDdkWPpfaadvileLyedkageyfvrvlYqe
subfamily_HP2-Group1_pd Subfamily HP2-Group1 53-304 7.7e-15 46.1 In-house 93-362 (422) alignment 
Range on Protein: 53-304
Range on HMM: 93-362/422.0
NQLTNVGIDQATKLGKFLRRRY--QGSVLPVFDRKKISIRSSDADRAIETAQSVATALFPPDGLQVWNeekfrfWQPIPIRTNGKPDPMLRPSKIQCPA-
 ||| .|  |    |. ||. |  .| . . .|  .. .|| |  |.| .||..   ..|.|.    .       | ... |  |    . .    ||  
aqltleGykqqelnGqilrkvyvdtGflkssldssevylrsddesrtilsaqalilGmypqdtkaedr......aqvvdlytrdklfdsieanadlcpkl

--YQRIVAEER---KKIE-SEINVKYKRELEIISNHT------SH----------QTKYGNIKDVYNVILEHY-NGLPFPNWIDEKVNgKSLLDTIaeIR
  |..   .     ....   ...  . .  . || .      ||          .    |..|. . .  |.  .. .|. . | .  |. || .  . 
seyntqflksdtwlnhlkgitkelllevskalGsnkslgsggcshtlylpiavtrkldidnledlvdclithqchnaaipdkltedla.krgldel..ly

RIARLQLFNSRA-KAKFMAGYLINSWTESLVLASQHISPKKALLYSSHDGTLSALMYGLGISNHQLIPYTACIMIELHT
|     .. |.  .|.   |.|.    . .  . .  . .| |||| ||.||  |.  |.... .  ||.. ...||  
rsysslkypsvekyarvGiGfllkdiwkevnesltGedlrkfllysGhdttliqllsalnvdefkwppyasllllelle
0048955 Phosphoglycerate mutase-like 25-310 3.1e-11 36.2 In-house 5-219 (240) alignment 
Range on Protein: 25-310
Range on HMM: 5-219/240.0
VWRHGDRAP--ENLPYPsdphnetfwpRGWNQLTNVGIDQATKLGKFLRRRyqgsvLPVFDRkkisIRSSDADRAIETAQSVATAL----FPPDGLQVWN
..||| .    |.. .           .   .||  |. || .||..|...      . ||.    . ||.. |||.||. .| ||     |.  .  ..
LvRHGesewnaegrlqg..........wtDvpLtelGreqaralgerLadl.....gikfdl....vysSpllRaiqTaeiiaealglpllpvvvdprlr

EEKFRFWQPipirtngkpdpmlrpskiqcpayqrivaeerkkieseinvkykreleiisnhtshqtkygnikDVYNVILEHYNGLPFPNWIDEK------
|  |  ..                                                                  .. | |... . .  . |.       
Erdfgaleg...............................................................ltldeiaekfpeelvlwlrdpldvrppl

-----------------------VNGKSLLDTIAEIRRIARLQLFNsrakakfmagylinswteslvlasqHISPKKALLYSSHDGTLSALMY-GLGISN
                        .| || |..| ...  .  | .                         .. | |  |  || |.. ||.   ||.. 
lelldellllldlryalldedllpggEsladvaaRvlaaleellar.........................alkpgknvlvVsHggvirallayllglpl

HQL----IPYTACIMIELHTGnnvkI
...    ||..... .||. |    .
eeilrlnipngsvtvlelddg....l
His_Phos_1 Histidine phosphatase superfamily (branch 1) 23-126 5.1e-11 35.7 Pfam-A 2-69 (158) alignment 
Range on Protein: 23-126
Range on HMM: 2-69/158.0
LAVWRHGDRApenlpypsdpHNETFWPRGWNQ--LTNVGIDQATKLGKFLRRryqgsvlpvFDRKKISIRSSDADRAIETAQSVATalfppdglqvwnee
| . ||| .           .|.    .||..  ||. |..|| .||| |.|          | .   . .|.  |||.||....               
lylvRHGese..........wnkegrlqgwsdvpLtekGreqarelgkkLkr.........adlpidavytSplkRaiqTaeille..............

kfrfwQ
     .
.....e
His_Phos_1 Histidine phosphatase superfamily (branch 1) 23-126 5.1e-11 35.7 In-house 2-69 (158) alignment 
Range on Protein: 23-126
Range on HMM: 2-69/158.0
LAVWRHGDRApenlpypsdpHNETFWPRGWNQ--LTNVGIDQATKLGKFLRRryqgsvlpvFDRKKISIRSSDADRAIETAQSVATalfppdglqvwnee
| . ||| .           .|.    .||..  ||. |..|| .||| |.|          | .   . .|.  |||.||....               
lylvRHGese..........wnkegrlqgwsdvpLtekGreqarelgkkLkr.........adlpidavytSplkRaiqTaeille..............

kfrfwQ
     .
.....e
0051064 Phosphoglycerate mutase-like 24-316 1.5e-10 34.0 In-house 7-233 (241) alignment 
Range on Protein: 24-316
Range on HMM: 7-233/241.0
AVWRHGDRAP--ENLPYPsdphnetfwpRGWNQLTNVGIDQATKLGKFLRRRyqgsvLPVFDrkkiSIRSSDADRAIETAQSVATALFPPDglqvwneek
 ..||| .    |.. .           .   .||  |. || .||..|...     .. ||     . ||.. |||.||. .| ||  |.         
yLvRHGesewnaegrlqg..........wtDvpLtelGreqaralgerladl.....gikfd....avysSpllRaiqTaeiiaealglpl.........

frfwqpipirtngkpdpmlrpskiqcpayqrivaeerkkieseinvkykreLEIISNHTSHQTKYGNI-KDVYNVILEHYNGLPFPNWIDEK--------
                                                   |... ..  .   .|      .. | |..... .  . |.         
...................................................lpvvvdprlrEidfgalegltleeiaekfpeelvawlrdpldvrpplle

--------------------------------------------------Vngkslldtiaeirriarlqlfnsrakakfmagylinswteslvlasqhi
                                                                                                    
lldlllllldlryagllddllpggEsladvaaRvlpaleellarllldgkn.................................................

spkkaLLYSSHDGTLSALMYGL------GISNHQlIPYTACIMIELHTGN-NVKIYFRNTT
     .|  ||.|.. ||.  |      .. ... .|..... .||. .   |.... | |
.....vlvVsHggvirallayllglpleellrln.lpngsvtvleldddgkrvvlvllndt
subfamily_PXYLP1_pd Subfamily PXYLP1 53-312 2.5e-10 31.1 In-house 104-361 (419) alignment 
Range on Protein: 53-312
Range on HMM: 104-361/419.0
NQLTNVGIDQATKLGKFLRRRYQGS--VL---PVFDRKKISIRSSDADRaieTAQSVATALFppdglQVWNEEKfrfWQPIPIRTngKPDPMLRPSKIQC
 |||..|. |  ..|..||. |  .  .|     . . .. . .    |   | ||    |.      . ...|   .. | .|.  .|.      . .|
gqLtqkGvvqhLevGdllrkvYakklklLlkpnelssDevvlettrkrr...tlqsalally.....gllpkak...lkairvre..spsvafClgeCsC

PAYQRIVAEERK---KIESEINVKYKRELEIISNHTSHQTKYGNIKDVYNVILEHY-NGLPFPNWIDEKVNGK---SLLDTIAEIRRIARLQLFNsRAKA
|| .| . |. .   ..    ... .. .  . . |  ||.   | .. ...| .    ...|   .  |. .    | .   |...    ...  .   
PallrkrlekeadkqlLlrgkvldvmksvgetlkgtilqttlngisnpvdalltvlChnvslPcrreGcvepshvdvlhkladelsqrsakksyy.klsG

KFMAGYLINSWTESLVLASQHISPKKALLYSSHDGTLSALMYGLGISNHQLIPYTACIMIELHTGNNVKIYF
...|  |..   . .  . .  . .|  |||.|| ||. |. .||.|. ..| | . .. ||.  .. | |.
llraypllrdivsrmlkiieGvdkekfvlysghDvtlrplvaaLglseartiayasrlvfelyrreaskeyy
0036777 Phosphoglycerate mutase-like 50-130 1.2e-07 24.2 In-house 24-99 (247) alignment 
Range on Protein: 50-130
Range on HMM: 24-99/247.0
RGWNQLTNVGIDQATKLGKFLRRRyqgsvLPVFDRkkisIRSSDADRAIETAQSVATAL----FPPDGLQVWNEEKFRFWQPIPI
.    ||  |. || .||..|...        ||.    . ||.. |||.||. .. ||     |.     ..|  .  ..  ..
wlDvpLtelGreqakalgellkel.....glpfda....vysSpllRAiqTaeiilealglsllpvvvdprLrErdyGalegltk
0036887 Phosphoglycerate mutase-like 48-125 2.3e-07 23.2 In-house 21-88 (202) alignment 
Range on Protein: 48-125
Range on HMM: 21-88/202.0
WPRGWNQLTNVGIDQATKLGKFLRrryqgsvlpvfDRKKISIRSSDADRAIETAQSVATALfppdGLQVW-----NEEKFRFW
  .    ||  |. || .||..|.           ...   . ||.. |||.||. .| ||    ||.|.     .|  |  .
qgdldvpLtelGreqaralgerla...........glpfdavysSpllRaiqTaeiiaeal....glpvivdprlrEidfgal
0049178 Phosphoglycerate mutase-like 54-127 2.3e-07 23.3 In-house 29-97 (243) alignment 
Range on Protein: 54-127
Range on HMM: 29-97/243.0
QLTNVGIDQATKLGKFLRRRyqgsvLPVFDrkkiSIRSSDADRAIETAQSVATAL----FPPDGLQVWNEEKFRFWQP
 ||  |. || .||..|...      . ||     . ||.. |||.||. .. ||     |.  .  ..|  |  .. 
pLtelGreqAralgellael.....glkfd....avysSplkRaiqTaeiilealglpllpvvvdprLrErdfGaleg
0037864 Phosphoglycerate mutase-like 50-133 2.5e-07 22.9 In-house 29-107 (211) alignment 
Range on Protein: 50-133
Range on HMM: 29-107/211.0
RGWNQLTNVGIDQATKLGKFLRRRyqgsvLPVFDrkkiSIRSSDADRAIETAQSVATAL----FPPDGLQVWNEEKFRFWQPIPIRTN
.    || .|. || .||..|...        ||     . ||.. |||.||. .. ||     |.  .  ..|  |  .. ...   
wldvpLtelGreqaralgealadl.....glpfd....avysSpllRaiqTaeiilealglpllpvevdprlrErdfgalegltleei
0043909 Phosphoglycerate mutase-like 52-118 3e-07 22.7 In-house 26-82 (249) alignment 
Range on Protein: 52-118
Range on HMM: 26-82/249.0
WNQLTNVGIDQATKLGKFLRRRyqgsvLPVFDRkkisIRSSDADRAIETAQSVATALFPPDgLQVWN
   ||  |. || .||..|...        ||.    . ||.. |||.||. .. .| ..  |.|  
DspLtelGreqaralgealkel.....gipfda....vysSplkRAiqTaeiileelgldk.lpvev
0039931 Phosphoglycerate mutase-like 52-148 3.2e-07 22.6 In-house 21-105 (219) alignment 
Range on Protein: 52-148
Range on HMM: 21-105/219.0
WNQLTNVGIDQATKLGKFLRRRyqgsvlpvfDRKKISIRSSDADRAIETAQSVataLFPPDGLQVWNEEKFRFWQPIPIRTNGKPDPMLRPSKIQCP
   ||  |. || .||..|...         . .   . ||.. |||.||. .    .|.  .  ..|  |  .. ...    .  |..    .. |
dspLterGreqaralgerlkdl.........glpfdavysSpllRaiqTaeii...glpveidprLrEidfgdlegltleeiaekypeelaawlrdp
subfamily_MINPP1_pd Subfamily MINPP1 53-184 4.5e-07 21.1 In-house 90-215 (420) alignment 
Range on Protein: 53-184
Range on HMM: 90-215/420.0
NQLTNVGIDQATKLGKFLRRRYQGSVLPVFDRKKISIRSSDADRAIETAQSVATALFPPDglQVWNEEKFRFWQPIPIRTNgkpDPMLRPSKiQCPAYQR
..|.  | ..  .|.| | ||.      |  ....|..|..  | ...||. |..|..    .| . |     | |    .   |..||. . .|..|. 
kslvaqgqeeleelakrlarrfpalfeevynpdsfsfastakkRtvksaqaFaeGLsetg..evlgdefnivlqeiseqes...dklLrffd.sCkkykn

IVAEERKKIESEINVKYKRELEIISNHTSHQT
 | ..  . ..| ... . ||. .... ....
kvkknelnlkeeeefleskelqkaleeiakrl
0053607 Phosphoglycerate mutase-like 52-130 4.6e-07 22.2 In-house 23-89 (191) alignment 
Range on Protein: 52-130
Range on HMM: 23-89/191.0
WNQLTNVGIDQATKLGKFLRRRyqgsvlpvfDRKKISIRSSDADRAIETAQSVataLFPPDGLQVWNEEKFRFWQPIPI
   ||  |. || .|...|...         . |   . ||.. ||..||. .    .|.  .  ..|  |  |. ...
dvpLtelGreqaralaellael.........glkfdavysSpllRarqTaeii...glpvevdprlrEidfgdwegltl
0035570 Phosphoglycerate mutase-like 52-126 6.7e-07 21.6 In-house 21-83 (219) alignment 
Range on Protein: 52-126
Range on HMM: 21-83/219.0
WNQLTNVGIDQATKLGKFLRRRYqgsvlpvfdRKKISIRSSDADRAIETAQSVatalfppdGLQV-----WNEEKFRFWQ
   ||  |. || .||..|...           .   . ||.. |||.||. .        ||.|     ..|  |  ..
dvpLterGreqaralgealadlg.........ipfdavysSpllRaiqTaeii........glpveidprLrEidfgdle
0050036 Phosphoglycerate mutase-like 52-133 1.3e-06 20.5 In-house 24-88 (171) alignment 
Range on Protein: 52-133
Range on HMM: 24-88/171.0
WNQLTNVGIDQATKLGKFLrrryqgsvlpvfdrKKISIRSSDADRAIETAQSVAtalFPPDGLQVWNEEKFRFWQPIPIRTN
   ||  |. || .||..|              .   . ||.  ||..||. ..    |.  .  ..|  |  |. ...   
dvpLtelgraqaralgell..............pfdavysSpllRArqTaelil...lpvivdprLrErdfGawegltldei
subfamily_TIGAR_pd Subfamily TIGAR 55-123 3.5e-06 18.9 In-house 27-84 (222) alignment 
Range on Protein: 55-123
Range on HMM: 27-84/222.0
LTNVGIDQATKLGKFLRRryqgsvlpvfdrKKIS-IRSSDADRAIETAQSVATALFPPDGLQVWNEEKFR
|.. |. || ...|.|              .||  | ||| .|| .||. .  ||   ....| .... |
LsekGveQakrvakrLsn............ekinyifsSdllRAkqTaeiilkalkekkreaverdkrLr