Gene DDB_G0272841 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP070_AA protein Get Run
DdisP070_AA_234-428 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 235-429 1.6e-50 163.7 In-house 14-189 (189) alignment 
Range on Protein: 235-429
Range on HMM: 14-189/189.0
EVVASMCRDESLTLAIHGGDLSYGLKE---EVWDTFGDIIEPLASRMPFMVIPGNWDVKEgalqPFVNRypmplvykqptieKKRISATastasittlqt
.      ....|.|.|| |||.| ||.   .|||.| ..||||||..|.||..||.....    .|...             |||.|..           
atllkeeeaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesds....nfsay.............kkrfsmp...........

NPNLYYSFRYTHVYFIMLSSYDPYSIGSLQYKWLVSELELANtMRQQYPWLIVIAHSPMYSSSTGHGGS---DIGV----RTQLEWLYDVYNVNIVFSGH
. | .|||.|..|.||.||... .| || ||||| ..|. || .|.. ||.||..|.||| |.. ..     .  |    |..||.|.. |.|....|||
sknewYsfdygpvhfislstevdfslgseqykWLekdLkean.nrkktpwiivmgHrPmYcsnkdeddctkeetlvrkglresledllykykvdlalsgH

DHGYE
.| ||
eHsYe
PAPL 235-428 1.6e-30 98.6 In-house 15-194 (194) alignment 
Range on Protein: 235-428
Range on HMM: 15-194/194.0
EVVASMCRDESLTLAIHGGDLSYGLKEE-VWDTFG--DIIEPLASRMPFMVIPGNWDVKegalqpfvnrypmplvyKQPTIEKKRISATASTASITTLQT
. .... ..... . .| |||.| ..|.  ||...  . |||||...|.||.||| . .                  . . .|.| |   |. . .. . 
krlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEee.................ynfsnykarfsmpgseegesnsse

NPNLYYSFRYTHVYFIMLSSYDPYSIGSLQYKWLvsELELANTMRQQYPWLIVIAHSPMYSSSTGHGG--SDIGVRTQLEWLYDVYNVNIVFSGHDHGY
. . .|||... |.||.|||.. ..  | ||.||  |..||.  |.. ||.||..| |||.|.. .    ..  ....|| |   |.|..|..|| | |
sgsnsysfetesvhfivlsseedvkekseqyewl..eedlakvnRsktPWiivmgHrpmYcsnkdkddckekakmlaaledllykygVDlvlaGHeHsY
Metallophos Calcineurin-like phosphoesterase 223-428 4.2e-14 46.3 Pfam-A 5-200 (200) alignment 
Range on Protein: 223-428
Range on HMM: 5-200/200.0
AFADSGTWGDVH----EVVASMCRDESLTLAIHGGDLSYGLKEEVWDTFGD--IIEPLASRMPFMVIPGNWDVKEGALQPFVNRYPMPL----VYKQPT-
...| . . |..    . .  .. .|  .| ...|||... ..  .         ..|.   |.....|| ... |.     . .  ..     .     
vigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangeeey

--IekkrisatastasittlqtnpnLyYSFRYTHVYFIMLSSYDPYSIGSLQYKWLvsELELANTMRQQYPWLIVIAHSPMYSSSTGHG--GSDIGVRTQ
                         . . .  | . .. ||.  |.  .| |...|  | .||. .| . .. |...| |..||   .   ||    .  
enl......................k.itllttsgelyglsglypllgdsaqeeql..eeflalplralvdgkilltHgplsssggsgddigselfgpda

LEWLYDVYNVNIVFSGHDHGY
|| |   |.| .|..||.| .
lekllekygvdlvlrGHtHkp
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 453-511 7e-14 43.3 Pfam-A 2-62 (62) alignment 
Range on Protein: 453-511
Range on HMM: 2-62/62.0
GTIHILGGTGGATADPWFDEQPNWSAVRESTSGYTKF-IAHKQTLQVTYLRMN-GTLGDHF
...||. |..|. .... ..||.|||.|||. ||... .. ...|.... | . |. .|.|
ApvhIvvGaAGnglskfskpqpewsafresdyGysrltvvNrthLhwefvrsddgqvlDsf
subfamily_PAPL_pd Subfamily PAPL 265-426 7.2e-12 37.0 In-house 60-210 (212) alignment 
Range on Protein: 265-426
Range on HMM: 60-210/212.0
DTFGDIIEPLASRMPFMVIPGNWDVKeGALQPFV------NRYPMPLVYKQPTIEkkrISATASTASITTLQTNPNLYYSFRYThvyfimLSSYDPYSIG
.|| |. .  . ..|..|..|| |.| | ..  .      .|. .| .| . ...   |. . .| ..  . |    . | ...      |.     |. 
etfedvftaeslqvpwyvvagnHDyk.GnvsaqiaYsklskrWkfpslyytksfk...ipdsnatvqlvlidtvllcgksddlk......legpvdvsla

SLQYKWLVSELELantmrQQYPWLIVIAHSPMYSSsTGHGGSDIgVRTQLEWLYDVYNVNIVFSGHDH
. |..|| .||.      ..  .|||  | |..|  . ||  .| .. .|. |   |||.  .|||||
eeqwawleeeLka.....seadylivaGhypvwsv.aehGptki.LvkrLkPlLekynvtaylsGhDh
ACP5 366-426 1.8e-09 29.5 In-house 139-197 (198) alignment 
Range on Protein: 366-426
Range on HMM: 139-197/198.0
VSELELANTMRQQYPWLIVIAHSPMYSSStGHGGSDIgVRTQLEWLYDVYNVNIVFSGHDH
  .   ..  ...  |.||. | |.|| .  || ..  .  .|. | . |.|.. ..||||
qlkwlekalakstadwkiVvGHhpvySig.ehgdtke.lverllpllkkykvdaYlnGHdH