Gene DDB_G0293460 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP073_AA protein Get Run
DdisP073_AA_133-354 phosphatase_domain Get Run
Domains
Summary
100200300400MKLILIFILSIIINCCFSIIPTSIRLAFTKNQDEVRVTWWTDEAMESPIVLFNNEMFVPNQDSVNGIEATVMSYDTLGFHGHPTTAILTGLQEMTQYFYSIGNKHSDEYSEVFNFTTGKINQIGGQVTPFSLSIFGDMGYGGKGLDSDFYTVANLYERSNDLAFNIHVGDIAYADETWETAINGNQTIWNQFLDSINPVSSHLIYMTCPGNHDIFYDLSVYRRTWLMPTDDNDQVSWYSFDYNGVHFVGISSEHDFLPLSPQHTWIENDLKNFRSNNPDNFIIMFAHRPFYCSTVWNWCNTTEDYLKKAFVYSLENLLYKYNVDMFISGHTHSSERTLPTYNGQPIGTYSNPKATIHITVGTGGNSEGNQHHWYPQPIWSSGYRISDNGFGLMNFINSTTLSWQFVANINNTIIDEIFITKGQFPAPCurated phosphatase domainPhoDMetallophosMetallophos_CPfam Domainsubfamily_ACP5_pd(1)PAPL(2)ACP5(3)subfamily_PAPL_pd(4)0053225(5)SubfamilyTransmembrane regionSignal peptide cleavage site
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 134-335 8e-64 207.0 In-house 1-189 (189) alignment
PAPL 134-333 1.4e-41 134.8 In-house 2-193 (194) alignment
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 353-416 1.5e-21 67.9 Pfam-A 1-61 (62) alignment
Metallophos Calcineurin-like phosphoesterase 135-333 3e-11 37.0 Pfam-A 6-199 (200) alignment
ACP5 134-332 1e-10 33.6 In-house 3-197 (198) alignment
PhoD PhoD-like phosphatase 81-180 1.8e-09 28.1 Pfam-A 61-153 (453) alignment
Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 153-365 4e-07 22.2 Pfam-A 17-139 (156) alignment
subfamily_PAPL_pd Subfamily PAPL 260-333 4e-07 21.5 In-house 150-211 (212) alignment