Gene DDB_G0284753 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily ACP2
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP090_AA protein Get Run
DdisP090_AA_61-447 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP2_pd Subfamily ACP2 66-451 6.4e-79 258.1 In-house 3-359 (361) alignment 
Range on Protein: 66-451
Range on HMM: 3-359/361.0
DNEKYKLKFIQIVTRHGRRTPESnRTPLTMWMcNSMdhlIsnkdsPRpncNPGQLTVLGIVDQINVGKIYRKLFIDHLGFLDSQYNKDQIFIRSTNTTRT
 .|..||||.|...|||.|.|.. ..| .... ...   .     |.   . |||| .|. .|...||..|| ......|||..||..||..||... ||
sseerkLkfvqvlfRHGdRsPln.typndkyk.ede...w.....pq...glGqLTeeGmqqqyeLGkfLrkrYvedtkfldakynpkqiyvrSsdvnRT

ISSARSLMHGLYGG----SFTDEQE--KSPHHSSfLVKPDNEENmYPRNSKKLVFLKNLIKQHPKVIkenqlSELEKFTEKINKIFENSKpEESS-Frar
..||.|...||..     ...||||  . |.|..  .. |.  .   .|...   |.. .|..|.|      ..||. .| ..|. |... |. . .   
lmSaqsvlaglfppetgvdypdeqeWqpvPvhtv.seeedlllr.akknCprydellqeakespevk.....klleenkelleklsestg.edidle...

gfRSYAgLVNSFDCFRN-NG-LPIPKGLTKDIiQRMYEESAKEFKSARY------FPEMSILGIGRFVDDLNKELKLKARNDPSVKDLKLSLYSGHDTTL
  ..|. |.... | |. .. |..|. ..... ....|| |...|.|..       .|.. | .| ....| ...| |.... . |.||| |||.|||||
..nfyq.lsdtlicerkyanelnlpewandel.fekleeladkvkeaefglnnektrelkklrgGpllnellenmkeklkceekkkklklflYSaHDttl

AALLVGYDMYeDKIHPVTSSTLEFLLMQDKDykepevvkitksiekeliNHQYVKVIYNHKPIHIGP------CKDkEvdGMCPLSEFLKISQSIIPTNY
||||. .... .| .| ..|.. . |....|                  ....|||.|...... .|      ||. |   .||||.| ||....||...
aalLeaLgif.ekkappyasaiivElyeedd..................gkplvkvlyrnetskdppeltlpgCkg.e..edCplskfkkivkpfipddv

DEQSKLT
||... .
delCeak
0048946 Phosphoglycerate mutase-like 62-447 3.3e-58 190.6 In-house 31-408 (447) alignment 
Range on Protein: 62-447
Range on HMM: 31-408/447.0
LEDYDNEKYKLKFIQIVTRHGRRTPESNRTPLTMWMCNSM------------------DHLISNkdSPRPNCNPGQLTVLGIVDQINVGKIYRKLFidhL
....  |...||..|...||| ||| .. .. ...... .                  .  ..|  .| ..|. |||| ||. .....|| .||..   |
ipepvpegcelkqvqvlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkn..eplwpcglgqLTplGreqlyelGkrlrkrY...l

GFLDsqyNKDQIFIRSTNTTRTISSARSLMHGLYGGSFTDEQEKSPHHSSflvKPDNEENMYPrnS-KKLVflknlikqhpKVIKENQLSELEKFTEKIN
|.|.   |...|..||... ||. ||.....||.. .  ..    | |.    . .| . ..|  | ....          ...|... .||....... 
gllp...npseiyvrssdvdRtlqSaqaflaGlfppepplgyqpipihtv...pssndnlllp..sCpafk..........ellkkelaeelkellkell

KIFENSKPeESSFRARGFRSYAGLVnSFDCFRNNGLPIPKGLTKDIIQRM-YEESAKEFKSARYFPEMSILGIGRFVDDLNKELKLKARNDPsvkdlKLS
. ...  .  . ...  . ..  |.  .. . ..  | .. .|.. .... | .... .  ..| .|.. |  | ..... . |. .. .|.     ||.
erlkkllg.glnltlsdvydlydll.lyetaihglsplcslftpeelevleyladlefyyeygygdelarlaggpllneilarledaisgds.....kly

LYSGHDTTLAALLVGYDMYEDKIH------------------PvTSSTLEFLLMQDKDYKEPEvvkitksiekeliNHQYVKVIYNHKPIHIGPCKDKEv
||..||||.||||   . ..|..                   |  .|.| | |.....  ...             .  ||.|.|| .|. .  |.... 
lyfaHdttiaallsaLglfddelplpadnlpfnrlfrsseivP.yasnlvfElyecpsslpsd.............geyyVrvlyngeplplpgCgsgp.

DGMCPLSEFLKISQSIIPtNYDEQ
.|.|||..|... ....| .....
gglCplddFkellkkflp.dwekl
0049059 Phosphoglycerate mutase-like 68-446 1.3e-57 188.7 In-house 39-432 (435) alignment 
Range on Protein: 68-446
Range on HMM: 39-432/435.0
EKYKLKFIQIVTRHGRRTPESNR--TPLTMWMC-----NSMDHLISNKDSPRPNCNPGQLTVLGIVDQINVGKIYRKLFidhlGFLdsqYNKDQIFIRST
|...||..|...||| ||| |.   .  ..| .     .. .. .|  ... .... |.|| ||...... || .||..    |||   ||.|....||.
egcelkqvqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrY....gfL...ynpdevyvrss

NTTRTISSARSLMHGLYGGSFTDEQEKSPHHSSFLVKPDNEENMY----PRNSKKLVFLKNLIKQHPKVIKENqlseLEKFTEKINKIFENSKpeessFR
.. ||. ||.....||..... ..|  .|..  ..| ..  . ..    . . .... |.. ... .....      ||.... ....... .     . 
dvdRtlqSaqaflaGlfppeilgsqllnplnvyqpvpietvdsdndtlpydscpafdellkellasdeflelf....lerilkllqellpglg.....lt

ARGFRSYAGL--VNSFDCFRNNGLPIP--KGLTKDIIQRMYEESAKE-FKSARYFPEMSILGIGRFVDDLNKELKLKARNdPSVK--------------D
.  . .   |   ... . . .||| |  . .|......... .  | .   .| .|.. |  | ..... . |. .. . .|..              |
psdvldlydlckydtlllgyahglplpfcslfteeelevleyladlefyylygygdeiaklaggpllneilarledaing.dstnlnltldsnpatfpld

LKLSLYSGHDTTLAALLVGYDMYEDKIH---------------------PvTSSTLEFLLMQDKDYKEPevvkitksiekelinhqYVKVIYNHKPIHIG
|||.||..||||.|.||   ....|...                     |  .|.| | |....| .|.                 ||.|.|| |.... 
lklylyfaHdttiapllsaLglfddqlplpadntpfpeldrlfrtseivP.yasnlvfElyecpdgney.................yVrvlyngkvlplp

PCKDKEvDGMCPLSEFLKISQSIIPTNYDE
 |.... .|.|||..|... ....|... .
gcgsgp.gglCplddFkelvkkflpgddfd
0046349 Phosphoglycerate mutase-like 70-447 4.6e-57 187.0 In-house 5-389 (409) alignment 
Range on Protein: 70-447
Range on HMM: 5-389/409.0
YKLKFIQIVTRHGRRTPESN-----RTPLTMWMcnsmdhlisnkdspRPNCNPGQLTVLGIVDQINVGKIYRKLFIDhLGFLDSQ--YNKDQIFIRSTNT
..||..|...||| ||| ..       |...|.               ..|. |||| ||.......|| .||...| ||.|.|.  ||.|.|..||...
ceLkqvqvlfRHGaRtPtkklsflpnwpginwt..............ngpcgagqLTplGreqayelGkrlrkrYvd.lgLlpsnslynpdeiyvrssdv

TRTISSARSLMHGLYGGSFTDEQE------------KSPHHSSF---LVKPDNEENMYPRNSKKLVFL-KNLIKQHPKVIKEN---------QLSELEKF
 ||. ||.....||....  . .             . | .         .|.  . .. . ..|  | |. .|....|..           .|.|.  .
dRtlqSAqaflaGlfpplggeivpllrqdlldppfqpipidtvpiseddalddtllppdslcpaldkllkenlkslsevleflvdealldlelldetkdl

TEKINKIFENSKPEESSFraRGFRSYAGLVNSFDCFRNNGLPIPKG---LTKDIIQRMYEESAKEFKSARYFPEMSILGIGRFVDDLNKELKLKARNDPS
 .|. ... ...|  .    . .. ...| . . . . .|||.|.    .|......... .  |.   ....|.. |  | ..... . |. .. ..  
lkklaerlnselpglnlt..dpldvasllydtllyetahglplppwcdlftpeelkvlayladleyyylygsgelaklaggpllneilarledaisgknp

VK---DLKLSLYSGHDTTLAALLVGYDMYE-----DKIHPvTSSTLEFLLMQD-KDykepevvkitksiekeliNHQYVKVIYNHKPIHIgpCKDKEVdg
|.   ||||.||..||||.||||   . ..      .| |  .|.| | |... .|                  .  ||.|.||..|. .  ....|   
vtfpldlklylyfaHdttiaallsaLglfdrlfrssdipp.yasnlvfElyecpsd..................geyyVrvlynggplpl..pgcgeg..

mCPLSEFLKISQSIIPT----NYDEQ
 ||||||... ....|     ..|. 
.cplsefkellkkrlpgcgltdfdkl
0047369 Phosphoglycerate mutase-like 68-446 8.6e-57 186.2 In-house 40-434 (438) alignment 
Range on Protein: 68-446
Range on HMM: 40-434/438.0
EKYKLKFIQIVTRHGRRTPESNRTPLTMWMCNSMDHLISNKDSPR-------PNCNPGQLTVLGIVDQINVGKIYRKLFidhlGFLdsqyNKDQI-FIRS
|...||..|...||| ||| ..  .  ..... ...   ... |        ..|. |||| ||.......|| .||..    |.|    | ... ..||
egcelkqvqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrY....glL....npedvlyvrs

TNTTRTISSARSLMHGLYGGSFTDEQE-----KSPHHssflVKPDNEENM----YPRNSKKLVFLKNLIKQHPKVIKENqlseLEKFTEKINKIFENSKP
... ||. ||.....||.....|.|         |.|    . |.. . .    .  . ...  |.. ... .....      |........|...... 
sdvdRtlqSAqaflaGlfppegtgelapilwqpipih....tipesddfllnllpsdscpafdellkeflasdeflell....lkdilkrlkkllpglnl

EESSfrargFRSYAGL----VNSFDCFRNNGLPIPKGLTKDIIQRM-YEESAKEFKSARYFPEMSILGIGRFVDDLNKELKLKARNdPSVK---------
. |.     . ..  |       ....  . .| ..  |..... . | .... .    | .|.. | .| ..... . |. .. . .|..         
tpsd.....vldlydlcaydtlangyaglplspfcslftpeelevleyladlefyylygygnelaklaggpllneilarledaing.kstnlnltldsng

-----DLKLSLYSGHDTTLAALLVGYDMYEDKIH---------------------PvTSSTLEFLLMQDKDYKEPevvkitksiekelinhqYVKVIYNH
     ||||.||..||||.||||   ....|...                     |  .|.| | |..... .|.                 ||.|.||.
vtfPldlklylyfaHdttiaallsaLglfddtwplpglpldkialnrlfrsseivP.yasnlvfElyecpsdgey.................yVrvlyng

KPIHIGPCKDKEvDGMCPLSEFLKISQSIIPTNYDE
|....  |.... .|.|||..|... ....|....|
kvlplpgcgsgp.gglCplddFkelvkkllpgdfee
0048439 Phosphoglycerate mutase-like 68-441 1.3e-55 182.2 In-house 5-391 (391) alignment 
Range on Protein: 68-441
Range on HMM: 5-391/391.0
EKYKLKFIQIVTRHGRRTPESNRTP--LTMWMCnsmdhlisnkDSPRPNCNPGQLTVLGIVDQINVGKIYRKLFIDhLGFLDSQY--NKDQIFIRSTNTT
....||..|...||| ||| |. .     .. .          . |  .|..|.|| ||. .... |. .||...| ||.|.|.|  |......||... 
agcelkqvqvlfRHGaRtPtssypnkldpllnk..........llpngpcglgeLTplGreqlyelGrrlrkrYvd.lgllpskytlnpsevyvrssdvd

RTISSARSLMHGLYGG-SFTDEQEKSPHHSSFLVKPDnEENMYPRNSkkLVFLKNLIKQHPKVIKENQLSELEKFT----------EKINKIFENSKPEE
||. ||.....||... ..|        . . |  |    |..|.       |.. ... |.... ..| .|....          |..  .|.  . | 
RtlqSAqaflaGlfpplgltvilvivvesedpllnpl.pintcplle..dlllldalsalprfylseilerlaevlnrvlglnltaedvlslfdlcaket

SSFRA-----RGFRSYAGLVNSFDCFRNNGLPIPKGLTKDI-----IQRMYEESAKEFKSARYFPEMSILGIGRFVDDLNKELklKARNDpsvKDLKLSL
  .        .. .   | . . .   .|||.|. ||...     .. ...    ..    . .|.. | .| ..... . |  .|...   .|.||.|
aalgsllklssplcdlftlydtllyeyahglplpewltdellspellkqladlvnelyyyltgsgeiaklaggpllneilddl..vangp...sdpklyl

YSGHDTTLAALLVGYDMYED------KIhPVTSSTLEFLLMQDKDYkepevvkitksiekeliNHQYVKVIYNHK--------------------PIHIG
|..||||.||||   ....|      .. |  .|.| | |.....                  .  ||.|.||..                    .... 
yfaHdttiaallsaLglfndtlplpadl.ppyasnlvfElyecpsd.................geyyVrvlynggtldlprdltlldldefllrlvlplp

PCKDKeVDGMCPLSEFLKISQSIIP
 |... ..|.|||..|... ...||
gcgsg.pgglCplddFvelvkkrip
0049226 Phosphoglycerate mutase-like 71-446 2.9e-53 174.3 In-house 2-338 (342) alignment 
Range on Protein: 71-446
Range on HMM: 2-338/342.0
KLKFIQIVTRHGRRTPesnrtpltM----------WMcnsmdhlisnkdsprPNCNPGQLTVLGIVDQINVGKIYRKLFidhLGFLDSQYNKDQIFIRST
|||..|...||| |||        .          |                ..|. |.|| ||.......|. .||..   ||.|.| ||.|....||.
kLkqvqvliRHGdRtP........lakgpldflnewf...............wgcglgeLTplGreqayelGrrlrkrY...lgllpstynpdevyvrss

NTTRTISSARSLMHGLYGGSFTDEQEKSPH---HSSFLVKPDNEENMYPrNSKKLVFLKNLIKQHPkvikenQLSELEKFTEKINKIFENSKP----EES
.. ||. ||.....||.... |.. ..  .      . . ..|. .... ...    ...|.|. .      . .|...|.|.| ..... ..    . |
dvdRtlqSaqaflaGlfppeltpilvplldwqpipiitepesndtllll.pydscpnfdkllkell......kseevqlfleeildllkklskllglnls

sfrarGFRSYAG-LVNSFDCFRNNGLPIP---KGLTKDIIQRMYEESAKEFKSARYFPEMSILGIGRFVDDLNKELKLKARndpSVKDLKLSLYSGHDTT
     .... |  |.. . .  ..|||.|   .  | . .. .|... ...    | .|.. | .| ..... . |. .       .||||.||..||||
.....tlsdvadtlydlllyelahglplppwcslftleelkalyaldllyyygigygeeiarlaggpllneilarleeaie...gpsdlklylyfahdtt

LAALLVGYDMYEDKIHPvTSSTLEFLLMQDKdykepevvkitksiekeliNHQYVKVIYNHKP------IHIGPCkdkevDGMCPLSEFLKISQSIIPTN
.||||   ....|.. |  .|.| | |....                   .  ||.|.|| ..      ...  |     ||.|||.||... ....|..
iaallsalglfddqlPp.yasnlvfElyecd...................geyyVrvlynggvlslpvtlplpgc.....dglcpldefkelvkkflpgd

YDE
..|
fee
0053031 Phosphoglycerate mutase-like 71-446 1.2e-50 165.8 In-house 2-338 (342) alignment 
Range on Protein: 71-446
Range on HMM: 2-338/342.0
KLKFIQIVTRHGRRTPES--NRTPLTMWMCnsmdhlisnkdsprpNCNPGQLTVLGIVDQINVGKIYRKLFidhLGFLDSQYNKDQIFIRSTNTTRTISS
.||......||| |||.|  . .||  |..               .|. |.|| ||. .....|. .||..   ||.|.| ||.|....||... ||. |
eLkqvivlvRHGaRtPlskgpldplnewfy...............pcgageLTplGreqayelGrrlrkrY...lgllpstynpdevyvrssdvdRtlqS

ARSLMHGLYGGSFTDEQEKSPH---HSSFLVKPDNEENMYPrNSKKLVFLKNLIKQHPkvikenQLSELEKFTEKINKIFENSKPEESsFRARGFRS-YA
|.....||... .|.. .   .      . . .... ...| |..    ...|.|. .      ...|.....|.. ....   .    ... ....   
AqaflaGlfppegtpilnpllgwqpipihtepessdalllp.nydpcpafdkllkeal......aseevkellerylellqklskglg.ltlsdlldlvs

GLVNSFDCFRNNGLPIP---KGLTKDIIQRMYEESAKEFKSARYFPEMSILGIGRFVDDLNKELKLKARNdpsVKDLKLSLYSGHDTTLAALLVGYDMYe
 |.... .   .||| |   .  | . ....|... . .    . .|.. | .| ..... . |. |  .    .|||| ||..||||.||||   ... 
dlydlllyelahglplppwctlftleelkalyaldllyyyglgpgnelaklaggpllneilarleekisg...pldlklylyfahdttiaallsaLglf.

DKIHPVTSSTLEFLLMQDKdyKEpevvkitksiekelinhQYVKVIYNHK------PIHIGPCkdkevDGMCPLSEFLKISQSIIPTNYDE
|   |  .|.| | |..|.  .|                  ||.|.|| .      ....  |     ||.||||||... ....|.....
ddqlPpyasnlvfElyedp..ge.................yyVrvlynggtlseplvlplpgc.....dglcplsefkelvkkllpgdfek
subfamily_ACP6_pd Subfamily ACP6 115-452 4e-32 103.3 In-house 73-375 (376) alignment 
Range on Protein: 115-452
Range on HMM: 73-375/376.0
CNPGQLTVLGIVDQINVGKIYRKLFIDHLGFLDSQYNKDQIFIRSTNTTRTISSARSLMHGLYGGSFTDEQekspHHSSFLVKPDNEENMYPRNSKKLVF
.  ||||  |  .  ..|.  || ......||  ..| ....||||| .||. ||| |. ||||   .. .     .  .  . ..|| .||  ..    
afkGqLtkvGmqqvfdLGrkLrkrYvedikfLsqefnpqevyiRstnieRtlesarclvaGLygkiiiqke....lpiilytdeedeevlyPnrqrcpll

LKNLIKQHPKVikeNQLSELEKFTEKINKIFENSKPeessfraRGFrSYAGLVNSFDCFRNNGLPIPKgLTKDIIQRMYEESAKEFKSARY---FPE--M
 . . . . .     .|    ..|..|.. .. |.          .  . .| . .   .. .|..|  ..||.|... .   .|          ||  .
srayrsvrksa...islpGisedtkqiadvldisee.......kkl.dfvslrDniaArlaHnlkvpp.ilkdvidliekhAveelvvlleggdrpekei

SILGIGRFVDDLNKELKlkARNDPSVKDLKLSLYSGHDTTLAALLVGYDMYEDKIHPVTSStLEFLLMQDKDykepevvkitksiekeliNHQYVKVIYN
  | .|...... ..|.  . ..  ..  || ||| ||||| .||. .....||  | ... . . | .||.                  .. .|.|.|.
lklsvGkvlkeilenle..kakekeiparklrLysaHDttlmtLLlalgvFDdkWPpfaad.vileLyedka..................geyfvrvlYq

HKPIHIGPCKdkevDGMCPLSEFLKISQSII-PTNYDEQSKLTQ
 | ...  ..    ....||  | .. . .. | .| .. ||..
ekelrlrgse....edlvPlekFkallavlvlpkdyaaeCkled
His_Phos_2 Histidine phosphatase superfamily (branch 2) 71-377 6.3e-25 80.8 Pfam-A 1-333 (347) alignment 
Range on Protein: 71-377
Range on HMM: 1-333/347.0
KLKFIQIVTRHGRRTPESNRT--PLTMWMCNSM---DHLIS--------NKDSPRPNCNPGQLTVLGIVDQINVGKIYRKLFIdhlGFLDSQYNKDQIFI
.||. ..| ||| ||| ..        . .. .     | .        .|..    .  |.||  |   . ..|. .|. .    |.|..........|
eLkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYp...gllrdhltyedvki

RSTNTTRTISSARSLMHGLYGGSF-------TDEQEKSP-----------HHSSFLVKPDNEENMYPR-NSKKLVFLKNLIKQHPKVIKENQLSELEKFt
||..  |.. ||.... ||.| .         | .  |.           . . .| . ...  ...   .|     ..|.... ||..||  ..|... 
rssserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsal.

ekinkifensKPEE--SSFRAR-----------GfrsyaglvnsfdcfRNNGLPIPKGLTK---DIIQRMYEESAKEFKSA-RYFPEMSILGIGRFVDDL
           ..|   .| .|                          ......||.  ..   | ..  . |. .|.     . .|.     . .. .|
..........ctgednllfkerweklfreffeee..............kfdiskipelydtmkydalhnrqledleelyklygigdeeklkigllllnpl

NKELKLKARNDPSVKDLKLSLYSGHDTTLAALLVGYDMYE-----DKIHPVTSSTLEFLLM
 |... .....   .. || ||..||.....||   ...|     .   .  .| . | |.
lkkilsdleetqpsrhaklrlyfthDshiytllnaLgleekiareaspelpyasqivfely
His_Phos_2 Histidine phosphatase superfamily (branch 2) 71-377 6.3e-25 80.8 In-house 1-333 (347) alignment 
Range on Protein: 71-377
Range on HMM: 1-333/347.0
KLKFIQIVTRHGRRTPESNRT--PLTMWMCNSM---DHLIS--------NKDSPRPNCNPGQLTVLGIVDQINVGKIYRKLFIdhlGFLDSQYNKDQIFI
.||. ..| ||| ||| ..        . .. .     | .        .|..    .  |.||  |   . ..|. .|. .    |.|..........|
eLkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYp...gllrdhltyedvki

RSTNTTRTISSARSLMHGLYGGSF-------TDEQEKSP-----------HHSSFLVKPDNEENMYPR-NSKKLVFLKNLIKQHPKVIKENQLSELEKFt
||..  |.. ||.... ||.| .         | .  |.           . . .| . ...  ...   .|     ..|.... ||..||  ..|... 
rssserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsal.

ekinkifensKPEE--SSFRAR-----------GfrsyaglvnsfdcfRNNGLPIPKGLTK---DIIQRMYEESAKEFKSA-RYFPEMSILGIGRFVDDL
           ..|   .| .|                          ......||.  ..   | ..  . |. .|.     . .|.     . .. .|
..........ctgednllfkerweklfreffeee..............kfdiskipelydtmkydalhnrqledleelyklygigdeeklkigllllnpl

NKELKLKARNDPSVKDLKLSLYSGHDTTLAALLVGYDMYE-----DKIHPVTSSTLEFLLM
 |... .....   .. || ||..||.....||   ...|     .   .  .| . | |.
lkkilsdleetqpsrhaklrlyfthDshiytllnaLgleekiareaspelpyasqivfely
subfamily_HP2-Group1_pd Subfamily HP2-Group1 106-179 3e-14 44.2 In-house 81-153 (422) alignment 
Range on Protein: 106-179
Range on HMM: 81-153/422.0
SNKDSPRPNCNPGQLTVLGIVDQINVGKIYRKLFIDHlGFLDSQYNKDQIFIRSTNTTRTISSARSLMHGLYGG
. ...   .|  .|||. |  .|   |.| || ..|  ||| |...  ....|| . .||| ||..|. |.|  
ntreedaGdcavaqltleGykqqelnGqilrkvyvdt.GflkssldssevylrsddesrtilsaqalilGmypq
subfamily_HP2-Group1_pd Subfamily HP2-Group1 266-449 3.1e-14 44.1 In-house 251-417 (422) alignment 
Range on Protein: 266-449
Range on HMM: 251-417/422.0
LVNSFDCFRNNGLPIPKGLTKDIIQRMYEESAKEFKSARYFP---EMSILGIGRFVDDLNKELKlKARNDPSVKdlKLSLYSGHDTTLAALLVGYDMYED
||. .   .  .. ||..||.|...|. .|    ..|.  .|   . .  ||| .. |. ||.. .. .  ...  |..|||||||||  ||. ... | 
lvdclithqchnaaipdkltedlakrgldellyrsysslkypsvekyarvGiGfllkdiwkevn.esltGedlr..kfllysGhdttliqllsalnvdef

KIhPVTSStleFLLMqdkdykepEVVKITKSIEKElINHQYVKVIYNHKPIHIGPCKDKEvdgmCPLSEFLKISQSIIPTNYDEQSK
|  |  .|   .||.        |..... . .     .  |.|.|| |  ..  |. .|    |.. .| .  ...|| .  |. |
kw.ppyas...llll........ellevstapaas.tpqyavrvlynGklkklpfcdane....csyeqfeaylstviphddaedck
subfamily_MINPP1_pd Subfamily MINPP1 67-193 4.9e-12 37.4 In-house 26-162 (420) alignment 
Range on Protein: 67-193
Range on HMM: 26-162/420.0
NEKYKLKFIQIVTRHGRRTPESNRTPLTMWMCNSMDHLISNKDSPRPNCN-------------PGQLTVLGIVDQINVGKIYRKLFIDHLGfldSQYNKD
.|. ||. .||. ||| | |. .     . . .....  .. |     .|              ..|.. |  .  ...| . . | . ..    .||.|
eegCklvklqiiaRHGtRypskskikkiqetlekiknyseqldgklsilnedlesnleyetelekslvaqgqeeleelakrlarrfpalfe...evynpd

QIFIRSTNTTRTISSARSLMHGLYGGSFTDEQEKSPHHSS
.. ..||.. ||. || . ..|| ... . ..|  ... .
sfsfastakkRtvksaqaFaeGLsetgevlgdefnivlqe
subfamily_PXYLP1_pd Subfamily PXYLP1 114-177 1e-11 35.7 In-house 100-165 (419) alignment 
Range on Protein: 114-177
Range on HMM: 100-165/419.0
NCNPGQLTVLGIVDQINVGKIYRKLFIDHLGFL--DSQYNKDQIFIRSTNTTRTISSARSLMHGLY
 |. ||||  |.|  ..||.. ||..  .|..|  . ....|.. . .|. .||. || .|..||.
iCelgqLtqkGvvqhLevGdllrkvYakklklLlkpnelssDevvlettrkrrtlqsalallygll
subfamily_MINPP1_pd Subfamily MINPP1 314-440 1.1e-06 19.7 In-house 307-405 (420) alignment 
Range on Protein: 314-440
Range on HMM: 307-405/420.0
IgrfvddlnkelklkarndpsvkdlklsLYSGHDTTLAALLVGYDMYEDKIHPVTSSTLEfllMQDKDYKEPEVVKITKSIEKELIN---HQY-VKVIYN
                            |. .|..||  ||    .|.|... ..... .   .... ...  .|  .  .  .| .    || |.|. |
s...........................lrFaHaetllpllsllGlykDeekLtannyhk...lsnrkfrssvivpyaanlafvlydCskdqykvlvlln

HKPIHIGPCKDKEvdGMCPLSEFLKISQSII
 |....  |. .|  . |.|..|..| ..|.
ekvvkletcsege..ifCelqdfkeiykkiv