Gene ttm2 in Drosophila melanogaster

Synonym: CG12313, Dmel\CG12313, Dmel_CG12313, ttm2

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily TIM50
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP067_AA protein Get Run
DmelP067_AA_209-335 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TIM50_pd Subfamily TIM50 211-336 2e-64 207.4 In-house 1-126 (126) alignment 
Range on Protein: 211-336
Range on HMM: 1-126/126.0
TLVLEIKDVLVHPDWTYETGWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGCIMYRLVRDSTHFDGGHHVKNLDNLNRDLKRVVVVD
|||||.|||||||.|||.||||||||||||.||...|..|||||.|.|||.|..||.|.|||...|||||.||.|..  |.|||.|..|||||..|.|||
tlvlelkdvlvhpewtyktGwrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvd

WDRNSTKFHPSNSFSIPRWSGNDNDT
.|..|.|..|.|.... .|.||..|.
ldkksvklqpenalalkkweGnaddk
NIF NLI interacting factor-like phosphatase 210-357 3.8e-37 119.6 Pfam-A 1-159 (159) alignment 
Range on Protein: 210-357
Range on HMM: 1-159/159.0
YTLVLEIKDVLVHPDWTY-----------ETGWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDP-NGCIMYRLVRDSTHFDGGHHVKNLD
.||||.. ..|||  ...           .| ...|||||.| ||||..|..|.|..||..  .. |..|.||| .  . .|| |.|. .  |..||.|.
ktLVLDLDetLvhskekkdlkedgkkveektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyvKdLs

NLNRDLKRVVVVDWDRNSTKFHPSNSFSIPRWSGN-DNDTTLFELTSFLSVLGtSEiDDVR
 |.|||.|||.|| ...| ...|.|   |... |. |.||.| .|..||. |   . ||||
llgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpfleale.ks.ddvr
CPDc_SM00577 210-335 7.8e-32 102.3 In-house 3-145 (146) alignment 
Range on Protein: 210-335
Range on HMM: 3-145/146.0
YTLVLEIKDVLVHP----------DWTYE-----TGWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGCIMYR-LVRDSTHFDGGHHV
..|||.....|||           ... .     | ....|||.|| |||..||.||.|..|...  .. ...|.|||.. ..|| |.|.....  |...
kvLVlDLdetLvhsanmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkrllkyrvlyRqdcrlvkgkll

KN-LDNLNRDLKRVVVVDWDRNSTKFHPSNSFSIPRWSGNDND
|. |. |..||..||..| ...||...|.| . |.... . .|
kddlsllkvdlskvviiDnseestlvnpenalkikpyisalsd
subfamily_SCP_pd Subfamily SCP 234-336 2.8e-24 77.5 In-house 40-142 (142) alignment 
Range on Protein: 234-336
Range on HMM: 40-142/142.0
KKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGCIMYRLVRDSTHFDGGHHVKNLDNLNRDLKRVVVVDWDRNSTKFHPSNSFSIPRWSGND
 ||| || |||. .. ||.|..||       |..| || .. . .|| |.| .|  | .||.| .| ||||.|..||   .|  ||| |.  .  |  . 
lkrphvdeflkrvgelfevvlftaslakyadpvadlldkkkvlrarlfrescvfhkgnyvkdlsrlgrdlkkviivdnspasyifhpenavpveswfddk

NDT
.||
edt
subfamily_CTDSPL2_pd Subfamily CTDSPL2 233-335 3.9e-19 61.0 In-house 38-141 (142) alignment 
Range on Protein: 233-335
Range on HMM: 38-141/142.0
FKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGC-IMYRLVRDSTHFDGGHHVKNLDNLNRDLKRVVVVDWDRNSTKFHPSNSFSIPRWSG
 ..|| .  ||.. .| ||....|| . |    |.| |||.   | .|| |..  .  | ..|.|. | |||.....||   ..  .  .|   |  |  
vrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyikdlsilGrdlektiivdnspqafayqlenGipieswfe

NDND
..||
dend
subfamily_DULLARD_pd Subfamily DULLARD 229-336 5.8e-19 60.3 In-house 44-152 (153) alignment 
Range on Protein: 229-336
Range on HMM: 44-152/153.0
TGWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNG-CIMYRLVRDSTHFDGGHHVKNLDNLNRDLKRVVVVDWDRNSTKFHPSNSFSIP
. ..  ||| ||.||.  .|....|..||   .   ..|| || .   .  |. |..   . |...|.|  .. ||..|...|   .. ...| |.  | 
vlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvlesgkytkdlslvssdlssviilDnspvayrknpdnaipik

RWSGNDNDT
 |  ...||
swlsdpsdt
subfamily_FCP1_pd Subfamily FCP1 230-314 1e-08 27.4 In-house 42-127 (146) alignment 
Range on Protein: 230-314
Range on HMM: 42-127/146.0
GWRFKKRPGVDVFLKECAKYFEIVVYTAEQGVTVFPLVDALDPNGCIMY-RLVRDSTHFDGGHHVKNLDNL-NRDLKRVVVVDwDRN
 .  |.||..  ||.. .|..|. .|| ..   .  ..  |||.. .   |..     .|  ...|.|..| ..| . ||..| ||.
vyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrdelldassktkklkklfptddsmvviiD.Dre
DUF2840 Protein of unknown function (DUF2840) 306-343 3.9e-06 12.9 Pfam-A 25-62 (149) alignment 
Range on Protein: 306-343
Range on HMM: 25-62/149.0
VVVVDWDRNSTKFHPSNSFSIPRWSGNDNDTTLFELTS
  ..|. |  . |.| . |.. ||. ||  |.   |. 
eqildrrrrvvafapgavfafvRWaandfGtvvsrldi