Synonym: CG6691, Dmel\CG6691, Dmel_CG6691, ttm3
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_TIM50_pd | Subfamily TIM50 | 141-265 | 7.2e-63 | 202.4 | In-house | 1-125 (126) | alignment | ||
Range on Protein: 141-265
Range on HMM: 1-125/126.0
SLVLEIKDVLVHPDWTYQTGWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDPYGYIKYRLVRGATDLVEGQHTKNLDYLNRDLSRVIVVD
.||||.|||||||.|||.||||||||||||.||.|....||||..|||||.||.||.|.||| ..|.|||.| ||..|.|.|.|.|..||||||.|||||
tlvlelkdvlvhpewtyktGwrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvd
CDPYTTPLHPDNSLVLTKWLGNDDD
.|. .. |.|.|.|.|.|| ||.||
ldkksvklqpenalalkkweGnadd
|
|||||||||
NIF | NLI interacting factor-like phosphatase | 141-287 | 6.9e-37 | 118.8 | Pfam-A | 2-159 (159) | alignment | ||
Range on Protein: 141-287
Range on HMM: 2-159/159.0
SLVLEIKDVLVHPDWTY-----------QTGWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDP-YGYIKYRLVRGATDLVEGQHTKNLDY
|||.. ..||| ... .| ...|||||.|.||...|...|.||.|... ..| |.||.||| ..|.|| | . | .|...|.|..
tLVLDLDetLvhskekkdlkedgkkveektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyvKdLsl
LNRDLSRVIVVDCDPYTTPLHPDNSLVLTKWLGN-DDDVQLFDLTAFLQLIAeHQvNDVR
|.||||||..|| .|. |.||| . .... |. |.| .| .|. ||. .. .. .|||
lgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpfleale.ks.ddvr
|
|||||||||
CPDc_SM00577 | 140-264 | 7e-32 | 102.4 | In-house | 3-144 (146) | alignment | |||
Range on Protein: 140-264
Range on HMM: 3-144/146.0
YSLVLEIKDVLVHP----------DWTYQ-----TGWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDPYGYIKYR-LVRGATDLVEGQHT
. |||.....||| ... . | ....|||.||.||......||.||.||.. ..| ..||.||| ...||| |.| .. ||.|...
kvLVlDLdetLvhsanmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkrllkyrvlyRqdcrlvkgkll
KN-LDYLNRDLSRVIVVDCDPYTTPLHPDNSLVLTKWLGNDD
|. |. |..|||.|...| ... |...|.| |. ... . .
kddlsllkvdlskvviiDnseestlvnpenalkikpyisals
|
|||||||||
subfamily_SCP_pd | Subfamily SCP | 164-265 | 2e-22 | 71.5 | In-house | 40-141 (142) | alignment | ||
Range on Protein: 164-265
Range on HMM: 40-141/142.0
KKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDPYGYIKYRLVRGATDLVEGQHTKNLDYLNRDLSRVIVVDCDPYTTPLHPDNSLVLTKWLGND
||| || ||.. .. ||.|..|. | |..| || . ...|| | . .|.. |.| | |||..||.|| | . .||.|.. .. |. .
lkrphvdeflkrvgelfevvlftaslakyadpvadlldkkkvlrarlfrescvfhkgnyvkdlsrlgrdlkkviivdnspasyifhpenavpveswfddk
DD
.|
ed
|
|||||||||
subfamily_DULLARD_pd | Subfamily DULLARD | 159-266 | 1.4e-20 | 65.5 | In-house | 44-152 (153) | alignment | ||
Range on Protein: 159-266
Range on HMM: 44-152/153.0
TGWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDPY-GYIKYRLVRGATDLVEGQHTKNLDYLNRDLSRVIVVDCDPYTTPLHPDNSLVLT
. .. ||| ||.||.. |. ...||.|. . | ...| || | .| |. | | .|..||.| .. |||.||..| |.. .|||.. ..
vlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvlesgkytkdlslvssdlssviilDnspvayrknpdnaipik
KWLGNDDDV
|| ...|.
swlsdpsdt
|
|||||||||
subfamily_CTDSPL2_pd | Subfamily CTDSPL2 | 163-265 | 2.8e-20 | 64.8 | In-house | 38-141 (142) | alignment | ||
Range on Protein: 163-265
Range on HMM: 38-141/142.0
FKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDPYGY-IKYRLVRGATDLVEGQHTKNLDYLNRDLSRVIVVDCDPYTTPLHPDNSLVLTKWLG
..|| . ||.. |. ||....|. . . | ||| ||| ||.|| | |.|.. |.|. | |||...|.|| | . . .| . . |
vrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyikdlsilGrdlektiivdnspqafayqlenGipieswfe
NDDD
...|
dend
|
|||||||||
subfamily_FCP1_pd | Subfamily FCP1 | 160-240 | 1.2e-06 | 20.6 | In-house | 42-124 (146) | alignment | ||
Range on Protein: 160-240
Range on HMM: 42-124/146.0
GWRFKKRPGVDYFLQQCSRNFEIVIYTSEQGMTAFPLLDALDPYGYIKYRLVRGATD-LVEGQHTKNLDY-LNRDLSRVIVVD
. |.||.. ||.. |. .|. ||| .. . | . ||| . . . . . | . ..||.|. ...| | |...|
vyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrdelldassktkklkklfptddsmvviiD
|