Gene ttm50 in Drosophila melanogaster

Synonym: CG2713, Dmel\CG2713, EG:95B7.3, Gp99, i238, i90, Dmel_CG2713, ttm50

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily TIM50
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP069_AA protein Get Run
DmelP069_AA_227-354 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TIM50_pd Subfamily TIM50 230-354 2.6e-66 213.5 In-house 1-125 (126) alignment 
Range on Protein: 230-354
Range on HMM: 1-125/126.0
TLVLEMKDVLVHPDWTYQTGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDPNGYIMYRLVRDATHFVDGHHVKNLDNLNRDLKKVIVVD
|||||.|||||||.|||.||||||||||||.|| ..|. |||||||.|||.|..|..|.|||...|||||.||||..|||.|||.|..|||||.||||||
tlvlelkdvlvhpewtyktGwrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvd

WDANATKMHPDNTFGLARWHGNDDD
.|....|..|.|.. |..|.||.||
ldkksvklqpenalalkkweGnadd
NIF NLI interacting factor-like phosphatase 229-376 6.1e-38 122.2 Pfam-A 1-159 (159) alignment 
Range on Protein: 229-376
Range on HMM: 1-159/159.0
YTLVLEMKDVLVHPDWTY-----------QTGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDP-NGYIMYRLVRDATHFVDGHHVKNLD
.||||.. ..|||  ...           .| ...|||||.|.|| |..|..|.|.|||.. ... |.||.||| . .. .|| |. . . .|..||.|.
ktLVLDLDetLvhskekkdlkedgkkveektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyvKdLs

NLNRDLKKVIVVDWDANATKMHPDNTFGLARWHGN-DDDGQLLDLIAFLKIIAqNNvDDVR
 |.|||..|..|| .... ...|||.  . .. |. |.| .||.|. ||. .. .. ||||
llgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpfleale.ks.ddvr
CPDc_SM00577 228-354 4.8e-33 106.2 In-house 2-145 (146) alignment 
Range on Protein: 228-354
Range on HMM: 2-145/146.0
RYTLVLEMKDVLVHP----------DWTYQ-----TGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDPNGYIMYR-LVRDATHFVDGHH
...|||.....|||           ... .     | ....|||.||.||...|| ||.|.||... ... .|||.|||.....|| |.|.....|.|..
kkvLVlDLdetLvhsanmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkrllkyrvlyRqdcrlvkgkl

VKN-LDNLNRDLKKVIVVDWDANATKMHPDNTFGLARWHGNDDD
.|. |. |..||.||...| . ..|...|.| .   ... . .|
lkddlsllkvdlskvviiDnseestlvnpenalkikpyisalsd
subfamily_SCP_pd Subfamily SCP 253-354 5.7e-24 76.5 In-house 40-141 (142) alignment 
Range on Protein: 253-354
Range on HMM: 40-141/142.0
KKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDPNGYIMYRLVRDATHFVDGHHVKNLDNLNRDLKKVIVVDWDANATKMHPDNTFGLARWHGND
 ||| ||.|| . .. ||.|.|||       |..| || .. . .|| |.. .|  | .||.| .| |||||||.||   ..  .||.|.  .. |  . 
lkrphvdeflkrvgelfevvlftaslakyadpvadlldkkkvlrarlfrescvfhkgnyvkdlsrlgrdlkkviivdnspasyifhpenavpveswfddk

DD
.|
ed
subfamily_CTDSPL2_pd Subfamily CTDSPL2 243-354 7e-21 66.7 In-house 31-141 (142) alignment 
Range on Protein: 243-354
Range on HMM: 31-141/142.0
DWTYQTgwRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDPNGY-IMYRLVRDATHFVDGHHVKNLDNLNRDLKKVIVVDWDANATKMHPDN
. |||     ..|| . .|| . .| ||...||| . .    .|| |||.   | .|| |.   .||| ..|.|. | |||.|.|.||  ..|  .  .|
nktyqv..yvrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyikdlsilGrdlektiivdnspqafayqlen

TFGLARWHGNDDD
   .  |. ...|
Gipieswfedend
subfamily_DULLARD_pd Subfamily DULLARD 248-354 4.1e-18 57.5 In-house 44-151 (153) alignment 
Range on Protein: 248-354
Range on HMM: 44-151/153.0
TGWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDPNG-YIMYRLVRDATHFVDGHHVKNLDNLNRDLKKVIVVDWDANATKMHPDNTFGLA
. ..  ||| ||.||   .| ...|.|||   .   ...| || .   .  |. |.     .|...|.|  .. ||..||..|  ..| ...|||.  . 
vlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvlesgkytkdlslvssdlssviilDnspvayrknpdnaipik

RWHGNDDD
 |  ...|
swlsdpsd
subfamily_FCP1_pd Subfamily FCP1 249-330 1.4e-07 23.7 In-house 42-125 (146) alignment 
Range on Protein: 249-330
Range on HMM: 42-125/146.0
GWRFKKRPGVDHFLAECAKDFEIVVFTAEQGMTVFPILDALDPNGYIMY-RLVRDATHFVDGHHVKNLDNL-NRDLKKVIVVDW
 .  |.||.. .||.. .| .|. ..| .. . .  |   |||.. .   |..     .   ...|.|..| ..| . |...| 
vyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrdelldassktkklkklfptddsmvviiDD
Hox9_act Hox9 activation region 25-138 9.6e-06 12.2 Pfam-A 66-172 (182) alignment 
Range on Protein: 25-138
Range on HMM: 66-172/182.0
HIHQHR--ALGNHYHHYHqhyQHQHHLLHHQQQYLRLFtCTALPAAApaLFSILHTARGYssTTKQEAGATGPNDAPEVAPNAPLLaKLFPQTSPEVDSN
..|..   |.   ||.|    ..| ||   . .|.|     ....|.   |. |.. | |  ..| |. ..   .  ..  ...|| . . . |......
pvhpqssaavpavYhpYv...hpqshlpaadgrYvrsW.Ldpisral..sftglsssrhy..giKpepllgkrgecttletetlll.seytlgssstaee

AEQERKKREEEEEKEN
.|..... .||...|.
keekeaaeseesseee