Gene CG6656 in Drosophila melanogaster

Synonym: Dmel\CG6656, Dmel_CG6656, CG6656

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily ACP2
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP112_AA protein Get Run
DmelP112_AA_39-391 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP2_pd Subfamily ACP2 40-390 2.1e-100 328.7 In-house 7-360 (361) alignment 
Range on Protein: 40-390
Range on HMM: 7-360/361.0
RNLRMISILFRHGAKNPSGFYPLDPHAAHDWQGGMGALTPKGSLQAYNLGRNLRMRY---YRLLPPNslYTQQQVNVLSSAAERCVMSAQSVLAGMMPPl
|.|.....|||||...|.  || |..  ..|..|.| ||..|  |.|.||. || ||   ...|...  |...|..| || ..|..|||||||||..|| 
rkLkfvqvlfRHGdRsPlntypndkykedewpqglGqLTeeGmqqqyeLGkfLrkrYvedtkfldak..ynpkqiyvrSsdvnRTlmSaqsvlaglfpp.

ENKNVLP--IPWQPVAVNTLSRNEDILLAQKKPCLKYDHILQKLYKSppPELQKLNEDNMELYKLLTKNTGKNISNVLDVElLYGTLKTEEE-AN-LVLP
|...  |  ..||||.| | | .|| || .||.| .||..||....|  ||..||.|.| ||.. |...||..|..  ... |. ||. |.. || | ||
etgvdypdeqeWqpvPvhtvseeedlllrakknCprydellqeakes..pevkklleenkelleklsestgedidlenfyq.lsdtlicerkyanelnlp

DWTENIYPEEIRPLAERSYMLFTE-----TNLMKRIKGGAFLTDILNKMQNKRKRNLNPD-RKIFLYSGHDVTLVNVMNSLGILDQttKLPEYASALAFE
.|... . |... ||. .... ..     |. .|...|| .| ..|..|..|.|...... .|.||||.|| ||......|||...  | |.||||...|
ewandelfekleeladkvkeaefglnnektrelkklrgGpllnellenmkeklkceekkkklklflYSaHDttlaalLeaLgifek..kappyasaiivE

LHHSksfSDGDFEVKLVYYYNSEDKFPkELTIPNC--DAPCSLTQFEASVKALLLDNYDETCENHP
|...   .||.. ||..|  ......| |||.|.|  .. |.|..|.  || ...|..|| ||...
lyee...ddgkplvkvlyrnetskdpp.eltlpgCkgeedCplskfkkivkpfipddvdelCeakt
0049226 Phosphoglycerate mutase-like 42-386 8.5e-78 254.9 In-house 3-340 (342) alignment 
Range on Protein: 42-386
Range on HMM: 3-340/342.0
LRMISILFRHGAKNPSGFYPLDPHAAHDWQGGMGALTPKGSLQAYNLGRNLRMRYYRLLppNSLYTQQQVNVLSSAAERCVMSAQSVLAGMMPPLE-NKN
|... .|.|||.. |  ..|||..    |. |.| |||.|  |||.||| || ||. ||  .| |....| | ||  .|...|||..|||. ||   ...
LkqvqvliRHGdRtPlakgpldflnewfwgcglgeLTplGreqayelGrrlrkrYlgll..pstynpdevyvrssdvdRtlqSaqaflaGlfppeltpil

VLPIPWQPVAVNTLSRNEDILLAQ-KKPCLKYDHILQKLYKSPppELQKLNEDNMELYKLLTKNTGKNISNVLDVEL-LYGTLKTEEEANLVLPDWTENI
|  ..|||. . | ..  | ||.  ...| ..|..|..|.||.  |.|...|. ..|.| |.|..| |.|.  ||   || .|. |   .| ||.|..  
vplldwqpipiitepesndtllllpydscpnfdkllkellkse..evqlfleeildllkklskllglnlstlsdvadtlydlllyelahglplppwcslf

YPEEIRPLAERS---YMLFTETNLMKRIKGGAFLTDILNKMQNKRKrnLNPDRKIFLYSGHDVTLVNVMNSLGILDqtTKLPEYASALAFELHHSKsfsd
..||.. |.. .   |.... .. . |. || .| .||. ......    .|.|..||..||.|.......||. |  ..||.|||.|.|||.. .    
tleelkalyaldllyyygigygeeiarlaggpllneilarleeaie..gpsdlklylyfahdttiaallsalglfd..dqlPpyasnlvfElyecd....

GDFEVKLVYYYNSEdKFPKELTIPNCDAPCSLTQFEASVKALLLDNYDETC
|.. |...|. ..  ..|..|..|.||  |.|..|   || .| ....| |
geyyVrvlynggvl.slpvtlplpgcdglcpldefkelvkkflpgdfeelC
0053031 Phosphoglycerate mutase-like 41-386 1.6e-76 250.7 In-house 2-340 (342) alignment 
Range on Protein: 41-386
Range on HMM: 2-340/342.0
NLRMISILFRHGAKNPSGFYPLDPHAAHDWQGGMGALTPKGSLQAYNLGRNLRMRYYRLLPpnSLYTQQQVNVLSSAAERCVMSAQSVLAGMMPPLE-NK
.|... .|.||||  |  ..||||.    .. |.| |||.| .|||.||| || ||. |||  | |....| | ||  .|...|||..|||. ||   ..
eLkqvivlvRHGaRtPlskgpldplnewfypcgageLTplGreqayelGrrlrkrYlgllp..stynpdevyvrssdvdRtlqSAqaflaGlfppegtpi

NVLPIPWQPVAVNTLSRNEDILLAQ-KKPCLKYDHILQKLYKSPppELQKLNEDNMELYKLLTKNTGKNISNVLD-VELLYGTLKTEEEANLVLPDWTEN
 . ...|||. . | ....| ||   ..|| ..|..|.. ..|.  |...|.|.  ||.. |.| .| ..|. || |  || .|. |   .| ||.|.  
lnpllgwqpipihtepessdalllpnydpcpafdkllkealase..evkellerylellqklskglgltlsdlldlvsdlydlllyelahglplppwctl

IYPEEIRPLAERSYM---LFTETNLMKRIKGGAFLTDILNKMQNKRKRnlNPDRKIFLYSGHDVTLVNVMNSLGILdqTTKLPEYASALAFELHHSKsfs
 ..||.. |......    .. .| . .. || .| .||. ...|..   ..|.|..||..|| |.......||.   ...|| ||| |.|||....   
ftleelkalyaldllyyyglgpgnelaklaggpllneilarleekisg..pldlklylyfahdttiaallsaLglf..ddqlPpyasnlvfElyedp...

dGDFEVKLVYYYNSEDkFPKELTIPNCDAPCSLTQFEASVKALLLDNYDETC
 |.. |...|  .. .  |..|..|.||  |.|..|   || ||...... |
.geyyVrvlynggtls.eplvlplpgcdglcplsefkelvkkllpgdfeklC
0046349 Phosphoglycerate mutase-like 41-388 1.9e-76 250.8 In-house 6-392 (409) alignment 
Range on Protein: 41-388
Range on HMM: 6-392/409.0
NLRMISILFRHGAKNPSG---F-YPLDPHAAHDWQGGMGALTPKGSLQAYNLGRNLRMRY--YRLLPPNSLYTQQQVNVLSSAAERCVMSAQSVLAGMMP
.|... .||||||  |     |  . ...  . .. |.| |||.|  |||.||. || ||    |||.||||..... | ||  .|...|||..|||. |
eLkqvqvlfRHGaRtPtkklsflpnwpginwtngpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynpdeiyvrssdvdRtlqSAqaflaGlfp

PLEN-------KNVLPIPWQPVAVNTLSRN-----EDILLAQKKPCLKYDHILQKLYKSpPPELQK-----------LNEDNMELYKLLTKNT-----GK
||.        ...|..|.||....|.. .     .|.||. ...| ..|..|.. .||  .| ..           |......|.| |.. .     | 
plggeivpllrqdlldppfqpipidtvpiseddalddtllppdslcpaldkllkenlks.lsevleflvdealldlelldetkdllkklaerlnselpgl

NISNVLDVEL-LYGTLKTEEEANLVLPDWTENIYPEEIRPLAE---RSYMLFTETNLMKRIKGGAFLTDILNKMQNKRKRNLNP----DRKIFLYSGHDV
|....||| . || ||. |   .| ||.|.. ..|||.. ||.    .| . . .. . ...|| .| .||. ...... . ..    |.|..||..||.
nltdpldvasllydtllyetahglplppwcdlftpeelkvlayladleyyylygsgelaklaggpllneilarledaisgknpvtfpldlklylyfaHdt

TLVNVMNSLGILDQT---TKLPEYASALAFELHHSksFSDGDFEVKLVYYYNsedkfpkELTIPNCDAPCSLTQFEASVKALLLD----NYDETCEN
|.......||. |..   ...| ||| |.|||..    |||.. |...|  .       .|..|.|. .|.| .|   .|  | .    ..|. |. 
tiaallsaLglfdrlfrssdippyasnlvfElyec..psdgeyyVrvlyngg.......plplpgcgegcplsefkellkkrlpgcgltdfdklCpl
0047369 Phosphoglycerate mutase-like 41-387 1.2e-71 235.2 In-house 43-437 (438) alignment 
Range on Protein: 41-387
Range on HMM: 43-437/438.0
NLRMISILFRHGAKNP-----------------SGFYPLDPHAAHD---WQGGMGALTPKGSLQAYNLGRNLRMRYyrllppNSLyTQQQV-NVLSSAAE
.|... .||||||  |                 ...|| .|.   .   .  |.| |||.|  |||.||. || ||      ..| ....|  | ||  .
elkqvqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrY......glL.npedvlyvrssdvd

RCVMSAQSVLAGMMPPLENKNVLPIPWQPVAVNTLSRNEDILLA--QKKPCLKYDHILQKLYKSppPELQKL-NEDNMELYKLLTKNTGKNISNVLDVEL
|...|||..|||. ||  ..   || |||. ..| ... | ||     ..| ..|..|.. . |  .| ..| ..| ....| |..... ..|.|||.  
RtlqSAqaflaGlfppegtgelapilwqpipihtipesddfllnllpsdscpafdellkeflas..deflelllkdilkrlkkllpglnltpsdvldlyd

L--YGTLkTEEEANLVLPDWTENIYPEEIRPLA----ERSYMLFTETNLMKRIKGGAFLTDILNKMQNKRKRNLNP--------------DRKIFLYSGH
|  |.||   . |.| |..... ..|||.. |.    .. |.|.. .| .... || .| .||. .... . . ..              |.|..||..|
lcaydtl.angyaglplspfcslftpeelevleyladlefyylygygnelaklaggpllneilarledaingkstnlnltldsngvtfPldlklylyfaH

DVTLVNVMNSLGILDQTTKL--------------------PeYASALAFELHHSKsfSDGDFEVKLVYyynsedkFPKELTIPNCDAP----CSLTQFEA
|.|.......||. | |. |                    | ||| |.|||.. .  |||.. |...|        .|.|..|.|.      |.|..|  
dttiaallsaLglfddtwplpglpldkialnrlfrsseivP.yasnlvfElyecp..sdgeyyVrvly.......ngkvlplpgcgsgpgglCplddFke

SVKALLLDNYDETCE
 || || ....| |.
lvkkllpgdfeelCg
0049059 Phosphoglycerate mutase-like 40-387 9.2e-68 222.1 In-house 41-435 (435) alignment 
Range on Protein: 40-387
Range on HMM: 41-435/435.0
RNLRMISILFRHGAKNPSG-----------------FYPLDPH---AAHDWQGGMGALTPKGSLQAYNLGRNLRMRYyrllppNSLYTQQQVNVLSSAAE
 .|... .||||||  |                   .|| .|.     ...  |.| |||.|  |||.||. || ||      ..||....| | ||  .
celkqvqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrY......gfLynpdevyvrssdvd

RCVMSAQSVLAGMMPPLENKNV---LPIPWQPVAVNTLSRNEDILlaQKKPCLKYDHILQKLYKSPppELQKL-NEDNMELYKLLTKNTGKNISNVLDVE
|...|||..|||. ||  ..      ....|||...| ..  |.|    ..| ..|..|..|..|.  | ..| .|.. .|.. |....| ..|.|||. 
RtlqSaqaflaGlfppeilgsqllnplnvyqpvpietvdsdndtl..pydscpafdellkellasd..eflelflerilkllqellpglgltpsdvldly

LL--YGTLKTEEEANLVLPdWTENIYPEEIRPLA----ERSYMLFTETNLMKRIKGGAFLTDILNKMQNKRKRNLNP--------------DRKIFLYSG
 |  | || ...  .| || ... ...||.. |.     . |.|.. .. . .. || .| .||. ...... .  .              |.|..||..
dlckydtlllgyahglplp.fcslfteeelevleyladlefyylygygdeiaklaggpllneilarledaingdstnlnltldsnpatfpldlklylyfa

HDVTLVNVMNSLGILDQTTKL--------------------PeYASALAFELHHSKSfsDGDFEVKLVYyyNSedkfpKELTIPNCDAP----CSLTQFE
|| |.......||. |... |                    | ||| |.|||.. ..  .... |...|  |.     |.|..|.|.      |.| .| 
HdttiapllsaLglfddqlplpadntpfpeldrlfrtseivP.yasnlvfElyecpd..gneyyVrvly..ng.....kvlplpgcgsgpgglCplddFk

ASVKALLLDNYDETCE
  || .| ... ..|.
elvkkflpgddfdeCg
0048946 Phosphoglycerate mutase-like 41-391 3.4e-67 220.2 In-house 40-414 (447) alignment 
Range on Protein: 41-391
Range on HMM: 40-414/447.0
NLRMISILFRHGAKNPSGFY-----------------------------PLDPHAAHDWQGGMGALTPKGSLQAYNLGRNLRMRYYRLLPpnslyTQQQV
.|... .||||||  |.  |                             . ....   |  |.| |||.|  |.|.||. || ||. |||     .....
elkqvqvlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkneplwpcglgqLTplGreqlyelGkrlrkrYlgllp.....npsei

NVLSSAAERCVMSAQSVLAGMMPPLenknvLPIPWQPVAVNTLSRNEDILLAQkkPCLKYDHILQKLYKsppPELQKLNEdnmELYKLLTKNTGKNISNV
 | ||  .|...|||..|||. ||      .|...||. . |.   .| ||..  .| .....|.| ..   .||..|..   ||...| | .| .  ..
yvrssdvdRtlqSaqaflaGlfppe.....pplgyqpipihtvpssndnlllp..sCpafkellkkela...eelkellk...ellerlkkllgglnltl

LDVELLYGTLKTEEEANlVLPDWTENIYPEEIRPLAERS----YMLFTETNLMKRIKGGAFLTDILNKMQNKRKRNLnpdrKIFLYSGHDVTLVNVMNSL
 ||  || .|. |  ..  |..... ..|||.. |.. .    |.... .. . |. || .| .||. .... . .     |..||..|| |.......|
sdvydlydlllyetaih.glsplcslftpeelevleyladlefyyeygygdelarlaggpllneilarledaisgds....klylyfaHdttiaallsaL

GILDQTTKL-----------------PeYASALAFELHHSKSfS---DGDFEVKLVYyyNSEdkfpkELTIPNCDAP----CSLTQFEASVKALlLDNYD
|. |..  |                 | ||| |.|||.. .| |   ||.. |...|  | |     .|..|.|.      |.| .|   .| . |....
glfddelplpadnlpfnrlfrsseivP.yasnlvfElyecps.slpsdgeyyVrvly..nge.....plplpgCgsgpgglCplddFkellkkf.lpdwe

ETCENHPT
. |... .
klCgltls
0048439 Phosphoglycerate mutase-like 41-375 4.3e-65 213.5 In-house 8-387 (391) alignment 
Range on Protein: 41-375
Range on HMM: 8-387/391.0
NLRMISILFRHGAKNPSGFYPL--DPHAAHDW---QGGMGALTPKGSLQAYNLGRNLRMRY--YRLLPPNSLYTQQQVNVLSSAAERCVMSAQSVLAGMM
.|... .||||||  |   ||   ||.  ...     |.| |||.|  |.|.||| || ||  . |||... .....| | ||  .|...|||..|||. 
elkqvqvlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqaflaGlf

PPLENKNVL-------PIPWQPVAVNTLSRNEDILLAQKKPCLKYD------HILQKLYKsPPPELQKLNEDNMELY---KLLTKNTGKNI---SNVLDV
|||... .|       .. ..|...|| .. || || .  ..| .         |.....   ..|.. .||. .|.   . .|. .| ..   |.. |.
pplgltvilvivvesedpllnplpintcplledlllldalsalprfylseilerlaevln.rvlglnltaedvlslfdlcaketaalgsllklssplcdl

ELLYGTLKTEEEANLVLPDW-TENIY----PEEIRPLAERSYMLFTETNLMKRIKGGAFLTDILNKMqnkrKRNLNPDRKIFLYSGHDVTLVNVMNSLGI
  || ||..|   .| ||.| |....    .. .. |... | ..| .. . .. || .| .||. .    . | ..|.|..||..|| |.......||.
ftlydtllyeyahglplpewltdellspellkqladlvnelyyyltgsgeiaklaggpllneilddl....vangpsdpklylyfaHdttiaallsaLgl

LDQTT----KLPEYASALAFELHHSKSfsDGDFEVKLVYyYNSEDKFPK--------------ELTIPNCDAP----CSLTQFEASVK
 . |.    .|| ||| |.|||.. .|  ||.. |...|  . . ..|                |..|.|.      |.| .| . ||
fndtlplpadlppyasnlvfElyecps..dgeyyVrvly.nggtldlprdltlldldefllrlvlplpgcgsgpgglCplddFvelvk
His_Phos_2 Histidine phosphatase superfamily (branch 2) 42-344 1.5e-49 161.8 Pfam-A 2-346 (347) alignment 
Range on Protein: 42-344
Range on HMM: 2-346/347.0
LRMISILFRHGAKNPSGFYPLDPHAAH--------------------------DWQGGMGALTPKGSLQAYNLGRNLRMRYYRLLPPNSLYtqQQVNVLS
|..  ...|||.  |   .... ...                           ... ..| ||..|  ||..||. || ||  ||.... |  ..| . |
LkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYpgllrdhlty..edvkirs

SAAERCVMSAQSVLAGMMPPLE----NKNVLPIPWQPVAVNTLSR----NEDILLAQKKPCLKYDHILQKLYKSPPPELQKLNEDNMELYK-LLTKN-TG
|  .|...|||...||...| .    ...  .  ....|..|..     ....|..... | ...  ..|. |   ....||...  | ..  |..  ||
sserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalctg

KNISNVLDVELLYGTLKTEEE--ANLVLPDWTEN-----IYPEEIRPLAErSYMLFTETNLMKRIKGGAFLTDILNKMQNKRKRNL-NPDRKIFLYSGHD
..  .  ..  .. .  .|||   .. .|.. ..     .  .....| |  | |   .. .|.  |. .|...|.|.... ...  ....|..||..||
ednllfkerweklfreffeeekfdiskipelydtmkydalhnrqledlee.lyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfthD

VTLVNVMNSLGILD----QTTKLPEYASALAFELHHSksfSDGDFEVKLVY
 ......| ||. .    .... . |||.. |||. .   |. .| |.|..
shiytllnaLgleekiareaspelpyasqivfelyed...sekkfyvrllf
His_Phos_2 Histidine phosphatase superfamily (branch 2) 42-344 1.5e-49 161.8 In-house 2-346 (347) alignment 
Range on Protein: 42-344
Range on HMM: 2-346/347.0
LRMISILFRHGAKNPSGFYPLDPHAAH--------------------------DWQGGMGALTPKGSLQAYNLGRNLRMRYYRLLPPNSLYtqQQVNVLS
|..  ...|||.  |   .... ...                           ... ..| ||..|  ||..||. || ||  ||.... |  ..| . |
LkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYpgllrdhlty..edvkirs

SAAERCVMSAQSVLAGMMPPLE----NKNVLPIPWQPVAVNTLSR----NEDILLAQKKPCLKYDHILQKLYKSPPPELQKLNEDNMELYK-LLTKN-TG
|  .|...|||...||...| .    ...  .  ....|..|..     ....|..... | ...  ..|. |   ....||...  | ..  |..  ||
sserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalctg

KNISNVLDVELLYGTLKTEEE--ANLVLPDWTEN-----IYPEEIRPLAErSYMLFTETNLMKRIKGGAFLTDILNKMQNKRKRNL-NPDRKIFLYSGHD
..  .  ..  .. .  .|||   .. .|.. ..     .  .....| |  | |   .. .|.  |. .|...|.|.... ...  ....|..||..||
ednllfkerweklfreffeeekfdiskipelydtmkydalhnrqledlee.lyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfthD

VTLVNVMNSLGILD----QTTKLPEYASALAFELHHSksfSDGDFEVKLVY
 ......| ||. .    .... . |||.. |||. .   |. .| |.|..
shiytllnaLgleekiareaspelpyasqivfelyed...sekkfyvrllf
subfamily_ACP6_pd Subfamily ACP6 71-388 3.3e-31 100.3 In-house 70-373 (376) alignment 
Range on Protein: 71-388
Range on HMM: 70-373/376.0
QGGM--GALTPKGSLQAYNLGRNLRMRYY---RLLPPNslYTQQQVNVLSSAAERCVMSAQSVLAGMMPPLENKNVLPIpwqpvAVNTLSRNEDILLAQK
.||.  | ||  |  |...|||.|| ||     .|...  .. |.| . |   || . ||. ..||.      . .|||      . |   .|..|. ..
kGGafkGqLtkvGmqqvfdLGrkLrkrYvedikfLsqe..fnpqevyiRstnieRtlesarclvaGLygkiiiqkelpi.....ilytdeedeevlyPnr

KPCLKYDHILQKLYKSPpPELQKLNEDNMELYKLLTKNTGKNISNVldveLLYGTLKTEEEANLVLPDWTENIYpEEIRPLAE-RSYMLFTETNL----M
. | .  .....  ||   .|.   ||  .. . |  .  |..  |     |   .  ... ||  |. ....  . |   |   . .|... .     .
qrcpllsrayrsvrksa.islpGisedtkqiadvldiseekkldfv....slrDniaArlaHnlkvppilkdvi.dliekhAveelvvlleggdrpekei

KRIKGGAFLTDILNKMQNKRKRNLNPdRKIFLYSGHDVTLVNVMNSLGILDQttKLPEYASALAFELHHSksfSDGDFEVKLvYYYNsedkfpKELTIPN
 ..  | .| .||............. ||. ||| ||.||. .. .||. |.  | |..|. ...||..     .|.. |.. .| .      ||| ...
lklsvGkvlkeilenlekakekeipa.rklrLysaHDttlmtLLlalgvFDd..kWPpfaadvileLyed...kageyfvrv.lYqe......kelrlrg

CD-APCSLTQFEASVKALL-LDNYDETCEN
..   . | .|.| .. |   ..| ..|. 
seedlvPlekFkallavlvlpkdyaaeCkl
subfamily_HP2-Group1_pd Subfamily HP2-Group1 73-389 6.2e-18 56.3 In-house 91-419 (422) alignment 
Range on Protein: 73-389
Range on HMM: 91-419/422.0
GMGALTPKGSLQAYNLGRNLRMRYYRLLPPNSLYTQQQVNVLSSAAERCVMSAQSVLAGMMPPLENKNVLpipWQPVAVNTLSRNEDILLAQKKPCLKYD
 .. || .|  |    |. ||  |      .| .   .| . |    | ..|||... || |.    .      | | ..|  .  | . |. . | |  
avaqltleGykqqelnGqilrkvyvdtGflkssldssevylrsddesrtilsaqalilGmypqdtkaedr...aqvvdlytrdklfdsieanadlcpkls

HILQKLYKSPPpELQKLNEDNMELYKLLTKNTGKNIS--------------------NVLDVELLYGTLKTEEEANLVLPD-WTENIYPEEIRPLAERSY
   ....||    |..|.   .|| . ..|  | |.|                    .. ..| |   |.|    |. .||  ||... . .  |  |||
eyntqflksdt.wlnhlkgitkelllevskalGsnkslgsggcshtlylpiavtrkldidnledlvdclithqchnaaipdkltedlakrgldellyrsy

MLFTETNLMK--RIKGGAFLTDILNKMQnkRKRNLNPDRKIFLYSGHDVTLVNVMNSLGILDqtTKLPEYASALAFELHHSKSFSD---GDFEVKLVYyy
  .      |  |.  | .| || ....  .  . .  ||. |||||| ||.... .|.. .   | | ||| | .|| .  .  .    .. |...|  
sslkypsvekyarvGiGfllkdiwkevn..esltGedlrkfllysGhdttliqllsalnvde..fkwppyasllllellevstapaastpqyavrvly..

NSedkfpKELTIPNCDA-PCSLTQFEASVKALLLDNYDETCENH
|      | ...| ||| .||. |||| ..... ..  | |...
nG.....klkklpfcdanecsyeqfeaylstviphddaedckvs
subfamily_PXYLP1_pd Subfamily PXYLP1 264-345 9.6e-13 39.1 In-house 292-367 (419) alignment 
Range on Protein: 264-345
Range on HMM: 292-367/419.0
KGGAFLTDILNKMQNKRKRnlNPDRKIFLYSGHDVTLVNVMNSLGIldQTTKLPEYASALAFELHHSKSFSdgDFEVKLVYY
.  ..|.||...|.   .       |  |||||||||  ....||.  . .....||| |.|||..... .  .. ....|.
raypllrdivsrmlkiieG..vdkekfvlysghDvtlrplvaaLgl..seartiayasrlvfelyrreask..eyylrvlyn
subfamily_MINPP1_pd Subfamily MINPP1 76-195 1.7e-12 38.9 In-house 91-205 (420) alignment 
Range on Protein: 76-195
Range on HMM: 91-205/420.0
ALTPKGSLQAYNLGRNLRMRYYRLLPpnSLYTQQQVNVLSSAAERCVMSAQSVLAGMmppLENKNVLPIPWQPVAVNTLSRNEDILLAQKKPCLKYDHIL
 |. .|  . ..|...|  |.  |.     | ...... |.| .|.| |||. . |.   .|...|| .  ..|.... . ..|.||   . | ||.. .
slvaqgqeeleelakrlarrfpalfe..evynpdsfsfastakkRtvksaqaFaeGL...setgevlgdefnivlqeiseqesdklLrffdsCkkyknkv

QKLYKSPPPELQKLNEDNME
.|   .   | ..|......
kknelnlkeeeefleskelq
His_Phos_1 Histidine phosphatase superfamily (branch 1) 47-141 3.3e-07 23.3 Pfam-A 3-79 (158) alignment 
Range on Protein: 47-141
Range on HMM: 3-79/158.0
ILFRHGAKNpsgfypldPHAAHDWQGGMGA-LTPKGSLQAYNLGRNLRMryyrllppnslyT-QQQVNVLSSAAERCVMSAQSVLAGMMPPLENKNV
.| |||  .         .... .||   . ||.||  || .||. |.               ..  .| .|   |..  |...|...  |..... 
ylvRHGese........wnkegrlqgwsdvpLtekGreqarelgkkLkr............adlpidavytSplkRaiqTaeilleeldipiikepr
His_Phos_1 Histidine phosphatase superfamily (branch 1) 47-141 3.3e-07 23.3 In-house 3-79 (158) alignment 
Range on Protein: 47-141
Range on HMM: 3-79/158.0
ILFRHGAKNpsgfypldPHAAHDWQGGMGA-LTPKGSLQAYNLGRNLRMryyrllppnslyT-QQQVNVLSSAAERCVMSAQSVLAGMMPPLENKNV
.| |||  .         .... .||   . ||.||  || .||. |.               ..  .| .|   |..  |...|...  |..... 
ylvRHGese........wnkegrlqgwsdvpLtekGreqarelgkkLkr............adlpidavytSplkRaiqTaeilleeldipiikepr
subfamily_PXYLP1_pd Subfamily PXYLP1 65-139 3.1e-06 17.6 In-house 94-171 (419) alignment 
Range on Protein: 65-139
Range on HMM: 94-171/419.0
HAAHDWQGGMGALTPKGSLQAYNLGRNLRMRYYRL---L-PPNSlYTQQQVNVLSSAAERCVMSAQSVLAGMMPPLENK
  .|.    .| ||.|| .|  ..|  ||  | .    |  ||  ... .|.. .    | . || ..| |..|  . |
lpnheriCelgqLtqkGvvqhLevGdllrkvYakklklLlkpne.lssDevvlettrkrrtlqsalallygllpkaklk