Gene twe in Drosophila melanogaster

Synonym: BG:DS02740.1, CG4965, Cdc25, Dmel\CG4965, TWINE, Twe, cdc25, l(2)35Fh, mat(2)syn-A, mat(2)synHB5, mat(2)syn[HB5], twn, Dmel_CG4965, twe

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC3
Superfamily CC3
Family CDC25
Subfamily CDC25
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP140_AA protein Get Run
DmelP140_AA_253-367 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_CDC25_pd Subfamily CDC25 255-366 6.7e-46 146.2 In-house 2-112 (114) alignment 
Range on Protein: 255-366
Range on HMM: 2-112/114.0
IQGEFDEQLGSqggYEIIDCRYPYEFLGGHIRGAKNLYTRGQIQEAFPT--LTSNQENRRIYVFHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYPEL
..|||.|.. .   ..|||||||||. ||||.||.|||.| ...|.. .   ....|.|.|..|||||||||||||.|.||..||......||.|.||||
lkgefeekiae...vliiDcRypyEyegGHikgavnlysreeveeellkkpkvkseekrkiiifhCefsseRgPklarllrevdrelnkeeypkleypel

YILHNGYKEFFGLY
|.|..||||||  .
yllekGYkeffeev
Subfamily.CDC25.PD 254-367 3.4e-45 144.2 In-house 3-116 (117) alignment 
Range on Protein: 254-367
Range on HMM: 3-116/117.0
LIQGEFDEQLGSqggYEIIDCRYPYEFLGGHIRGAKNLYTRGQIQEAF---PTLTSNQENRRIYVFHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYP
|..||..|.  .   |.|||||||||. ||||.||.|||.| ...|.|   |. ....|.|.|..|||||||||||||.|.||..||......||.|.||
llkgetkeliek...yiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleyp

ELYILHNGYKEFFGLYS
|||.|..||||||  ..
elylLegGykeffeeve
Family.CDC25.PD 254-367 3.4e-45 144.2 In-house 3-116 (117) alignment 
Range on Protein: 254-367
Range on HMM: 3-116/117.0
LIQGEFDEQLGSqggYEIIDCRYPYEFLGGHIRGAKNLYTRGQIQEAF---PTLTSNQENRRIYVFHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYP
|..||..|.  .   |.|||||||||. ||||.||.|||.| ...|.|   |. ....|.|.|..|||||||||||||.|.||..||......||.|.||
llkgetkeliek...yiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleyp

ELYILHNGYKEFFGLYS
|||.|..||||||  ..
elylLegGykeffeeve
Group.Cx5R-II.PD 254-367 3.4e-45 144.2 In-house 3-116 (117) alignment 
Range on Protein: 254-367
Range on HMM: 3-116/117.0
LIQGEFDEQLGSqggYEIIDCRYPYEFLGGHIRGAKNLYTRGQIQEAF---PTLTSNQENRRIYVFHCEFSSERGPKLLRYLRSNDRSQHTHNYPALDYP
|..||..|.  .   |.|||||||||. ||||.||.|||.| ...|.|   |. ....|.|.|..|||||||||||||.|.||..||......||.|.||
llkgetkeliek...yiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleyp

ELYILHNGYKEFFGLYS
|||.|..||||||  ..
elylLegGykeffeeve
Rhodanese Rhodanese-like domain 257-362 3.6e-13 42.0 Pfam-A 3-110 (113) alignment 
Range on Protein: 257-362
Range on HMM: 3-110/113.0
GEFDEQLgSQGGYEIIDCRYPYEFLGGHIRGAKNLYT-----------RGQIQEAFPTLTSNQENRRIYVFHCeFSSERGPKLLRYLRSNDRSQHTHNyp
 |. |.|  .... ..|.| |.|. .|||.|| |.             . ...| ....    .. . .|..| .|..|.  . . |.    ..  ..  
kelkell.ekekvvllDvRspeeyakghIpgAvnvpldslyprrdlffkdklaeeleesgkkldkdktvvvyc.rsgnrsggaaalllalilkelgyk..

aldypELYILHNGYKEF
     . |.|  |....
.....nvyvLdGGfeaw