Gene SSU72 in Homo sapiens

Synonym: HSPC182, PNAS-120, RP5-832C2.2, SSU72

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC2
Superfamily CC2
Family SSU72
Subfamily SSU72
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP113_AA protein Get Run
HsapP113_AA_2-194 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_SSU72_pd Subfamily SSU72 6-194 3.7e-104 335.5 In-house 1-189 (189) alignment
Range on Protein: 6-194
Range on HMM: 1-189/189.0
LRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDLF
||.|||||||||||.|||..|.|.||.|.|.|||..||||||. ||||||.|.|||...|.||..||||||||||.|.|||||.|||..|||||..|. |
lriavvcssnqnrsleahkllkkkGfnvksyGtgsavklPGpsidkPnvyefgttyediykdlkekdkelytqnGllemldrnrrikkaPerfqeekkkf

DLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQHTEDMENEIDELLQEFEEKSGRTFLHTVCFY
|..||.||||||.|||||.|||.....||||.||||.||.||||||||||.||.......||.|.||||.|.|||||. |..||...||
divltveervydavvedlesreeksskpvhvinvdikdnaeeatlGaflilelaeileksedledeideileefeektkrellhalafy

Ssu72 Ssu72-like protein 5-194 7.1e-91 292.3 Pfam-A 2-196 (196) alignment
Range on Protein: 5-194
Range on HMM: 2-196/196.0
PLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDL
 |..||||.||||||||||..|...||.|.|||||..||||||. ||||||.|.|||...|.||..||.|||..||.|.||.||..|| .|||||..|. 
klklavvCasnqnRsmeaHkvlkeagfdvksfGtgsavklPGpsidkPnvyeFgttYeeiykdleskdeelYeenGllkmlernrkikkaPerfqeekea

--FDLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQ--HTEDMENEIDELLQEFEEKS-GRTFLHTVCFY
  ||...||||||.|.|||||..||.|. .||||.||||.||||||..||. |.||.....  ..||.|.|..|.|.|||||. ....|.||.||
gkfdvvitceervfdavvedllereselnrpvhvinvdikDnheealvgakailelvealeeeaeedleeeveeilaefeekepklkllytvafy

Ssu72 Ssu72-like protein 5-194 7.1e-91 292.3 In-house 2-196 (196) alignment
Range on Protein: 5-194
Range on HMM: 2-196/196.0
PLRVAVVCSSNQNRSMEAHNILSKRGFSVRSFGTGTHVKLPGPAPDKPNVYDFKTTYDQMYNDLLRKDKELYTQNGILHMLDRNKRIKPRPERFQNCKDL
 |..||||.||||||||||..|...||.|.|||||..||||||. ||||||.|.|||...|.||..||.|||..||.|.||.||..|| .|||||..|. 
klklavvCasnqnRsmeaHkvlkeagfdvksfGtgsavklPGpsidkPnvyeFgttYeeiykdleskdeelYeenGllkmlernrkikkaPerfqeekea

--FDLILTCEERVYDQVVEDLNSREQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCIQ--HTEDMENEIDELLQEFEEKS-GRTFLHTVCFY
  ||...||||||.|.|||||..||.|. .||||.||||.||||||..||. |.||.....  ..||.|.|..|.|.|||||. ....|.||.||
gkfdvvitceervfdavvedllereselnrpvhvinvdikDnheealvgakailelvealeeeaeedleeeveeilaefeekepklkllytvafy

LMWPc_SSU72 6-177 6.9e-49 156.3 In-house 1-136 (137) alignment
Range on Protein: 6-177
Range on HMM: 1-136/137.0
LRVAVVCSSNQNRSMEAHNILSKR--GFSVRSFGTGTHVklPGPAPDKPnvydfkttydqmyndllrkDKELYTQNGIlhmldrnkRIKPRPERFQNC-K
|.|..||.||.||||||...|...  |..|.|.|||..|  |||..|||                   ..|||..||.        .|| .||..|..  
lkvlfVCasNinRSmeAeallkealeglevkSaGtgslv..pgpsidkp...................aeelykenGl........sikeapeklqeeel

DLFDLILTCEERVYDQVVEDLNSReQETCQPVHVVNVDIQDNHEEATLGAFLICELCQCiqhtedmenEIDELLQ
. |||..|.||||.|.|||||..| .|. ..|||.||||.|.||||. |.  |..|..          ...|||.
ekfDlvitleervfdavvedlper.selkrkvhvinvdikDpheeaiegfkaildliee.........rvkella

LMWPc_SSU72_ArsC 7-159 3.5e-36 114.9 In-house 2-126 (126) alignment
Range on Protein: 7-159
Range on HMM: 2-126/126.0
RVAVVCSSNQNRSMEAHNILSKR---GFSVRSFGTGTHVklPGPAPDkpnvydfkttydqmyndllRKDKELYTQNGIlhmldrnkRIKPRPERFQNC-K
.|..||..|..||..|...|.|    |. |.|.|||..|  ||. .|                   ... ||...|||        ..| .|...|.   
kvlfvClgNicRSpmAeavlkkavkkglnvsSaGtgaav..pgksid...................sravellkengi........elkhkprqlqeedl

DLFDLILTCEERVYDQVVEDLNSReqeTCQPVHVVNVDIQDNHEEATLGAFLICELC
. ||||||..||..|.|.|.|..|   ....||..|.|..|..|.|. |.  ...|.
kefdliltmdernkdevlellper...atkkvhllnldvkDpyegaesgfeevldli

0053360 Phosphotyrosine protein phosphatases I 3-41 1.1e-06 19.3 In-house 3-49 (157) alignment
Range on Protein: 3-41
Range on HMM: 3-49/157.0
SSPLRVAVVCSSNQNRSMEAHNILSKRG--------FSVRSFGTGTH
|....| .||  |  ||  |  .| ..         | |.| ||.. 
skmkkvLfvCtgNicRSpmAeallrhlleeaglgdrfevdSaGtsal

0048765 Phosphotyrosine protein phosphatases I 6-42 2.3e-06 18.3 In-house 3-48 (154) alignment
Range on Protein: 6-42
Range on HMM: 3-48/154.0
LRVAVVCSSNQNRSMEAHNILSKRG--------FSVRSFGTGT-HV
 .| .||  |  ||  |  .| ..         . |.| ||.. ||
kkvLfvCtgNicRSpmAeallrhlleeaglgdrvevdSaGtsayhv

0046251 Phosphotyrosine protein phosphatases I 3-41 7.8e-06 16.7 In-house 3-50 (159) alignment
Range on Protein: 3-41
Range on HMM: 3-50/159.0
SSPLRVAVVCSSNQNRSMEAHNILSKRG---------FSVRSFGTGTH
.....| .||  |  ||  |  .| ..          . | | ||...
lmkkkvlfvCtgNicRSpmAeallrhlledaglsdllievdSaGtsal

0042188 Phosphotyrosine protein phosphatases I 4-42 9.1e-06 16.4 In-house 3-45 (146) alignment
Range on Protein: 4-42
Range on HMM: 3-45/146.0
SPLRVAVVCSSNQNRSMEAHNILSKRG---FSVRSFGTGT-HV
....| .||  |  ||  |  .| ..    . |.| ||.. ||
kkkkvlfvCtgNicRSpmAeallrhllgdrvevdSAGtsayhv