Gene PPEF1 in Homo sapiens

Synonym: PP7, PPEF, PPP7C, PPP7CA, RP3-499B10.1, PPEF1

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PPP
Subfamily PPP7C
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP144_AA protein Get Run
HsapP144_AA_94-503 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPP7C_pd Subfamily PPP7C 102-501 1.2e-206 678.8 In-house 1-382 (383) alignment
Range on Protein: 102-501
Range on HMM: 1-382/383.0
DVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGD
.|.|||.||||..|||..... |.|||||...|||.|||..|.|.||||||.||.....|. |||||.|||||||||||.||.||||||||.||||||||
evedsytgprlslpltkdeveklieafkekkllhakyvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGd

FVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVE
||||||.|.|||.||....||||....||||||||...||||||.||. .||| |||.||..||...||||..|..|..||..|||||..|||.||...|
fvdrGkesveillillalllvypkevylnrGnhedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisdktdlelldkie

RNKMKSVLIPPTETNRDHDTDSKHNKVGVTfnahgriktngsptehltEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIR
|.|..||| ||...............| |.                  ..||.|..|||||||. |.||.|||.||||.|||||||.|.|.||.||.|||
rsklvsvlrpplkegeeaekekeessvkvd..................keewrqvldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllir

SHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSG
||||||||||..|| ||.||||||||||||||||||.||.. .|||..|||..|||. ..|||||...|.||.. |||.....||||...|. .|..|||
sheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltprivqyqaskatkkltlrqrvsiveesalrelrekllakksdlleefkkkdekksg





PPP_1 139-440 3.9e-111 363.5 In-house 2-264 (264) alignment
Range on Protein: 139-440
Range on HMM: 2-264/264.0
VLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLfLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM
..|.|.|.|| ||...|....... |.|.|.|||.||..||| |...|.|.||... |.|.||.|||||.|.|||..|.. .|.||..|.|.|||||. .
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDL.lklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrq

MNLRYGFTKEILhkYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDtdskhnkvgvtfnahgri
.. .|||.||.|  .| ..|.|...|......||.....|..||..|||.|...||.. .| ||.|....   ........|                  
vtkvygFkkEvl..kkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekd..................

ktngsptehlteheweqiIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYI
                  .|||.||.. ......|..||.|..||.|||.|.|.|..||..||.||.|.||||.....|||||||||||||||||||||.
..................vdillsddkeqeeavansiRGagylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayv

KL
||
kl

PPP_3 138-452 1.3e-101 332.2 In-house 2-270 (271) alignment
Range on Protein: 138-452
Range on HMM: 2-270/271.0
YVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLfLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDF
.. ..| |..| ||.... ... .. |..||.|||.||.|||| |...|||.||... |.|.||.|||||.|.|.|..|..  ..||...||.|||||. 
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDL.lelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsr

MMNLRYGFTKEILhkYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRdhdtdskhnkvgvtfnahgr
..| .|||.||.|  .| .||.... |.|....||.....|...||.|||.|.....   .. ...|....   .. ..                     
qinkvYgFkkevl..kkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldll....................

iktngsptehlteheweqiidilWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAY
                       .|... |.... |. || |..||||||...|.|..||..||.||.|.|||||.|||||||.|||.||.|..||.||.
.......................lssdpekeeglenskrGagllFgpdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagai

IKLCSGTTPRFFQYQ
.|| . .|..| |..
lkleealtsefkqle

PP2Ac_SM00156 134-453 3.8e-94 307.7 In-house 1-269 (271) alignment
Range on Protein: 134-453
Range on HMM: 1-269/271.0
LHAHYVLEVLFETKKVLKQMPNFTHIQtspsKEVTICGDLHGKLDDLFLIFYKNGlPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGN
|....|||.| |.|..|||..|.....    ..||..||.||.||||. .. ..| ......|||.||.||||..|||....|.   ..||....|.|||
lskeevlelleevkeilkqeknlvevs....apvtvvGdihGqlddllrllelag.eppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGn

HEDFMMNLRYGFTKEILHKYklhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISEttDLNLLHRVERNKMksvlipptetnrdhdtdskhnkvgvtfn
||. ..|  |||..|. .||   ||.|....||....||....||..||..|||.|.  .|. |..... |.                            
HEsssvnkiygfeeevkrky...gkeiyekfeeafsllPlaalvdskilcmhGGlsp..eleslddirklkr............................

ahgriktngspteHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSN
             . ...|....||.|||||. |. .| ...|| ...||.|.....|.|..||..||.||...||||...|.|.||||||.||..| ||
.............vkekpeegllidllwsdpeqkekgfqpskrglsvvFgedavkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsn

RGAYIKLCSGTTPRFFQYQV
 .|..|..........|.. 
kaavlkveknlklsieqlke

0045823 Metallo-dependent phosphatases 95-503 3.3e-92 302.6 In-house 4-370 (473) alignment
Range on Protein: 95-503
Range on HMM: 4-370/473.0
WDYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTspskEVTICGDLHGKLDDLFLIFYKNGLPSErN
. ..  | |......|.| ..|.  |.|||.| .|....|.....|..| |.|..||..||. ...      ....||.|| ||||  .. |.|.|.| .
vlklvlipvlrlltlpllfillglldldlliehlkkegllpeedllklldeakeilkkepnllelsm....rivviGDiHGqlddLlrllekigfppe.d

PYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYklhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISET-TD
 .||.||.|||| .|.|.| .|   .. ||.. .| |||||. ..|  ||| .|.|.||   | .. . . |. ..||.  .... ||..|||.|   . 
rlvflGDlvDrGpdslevlelllalkikypgnvfllrGNHElrllnglygfgdetleky...gedlyeeflewlrslPlaaviggkilfvHGGlspdlpl

LNLLHRVERnkmksVLIPPTetnrdhdtdskhnkvgvtfnahgriktngsptehlteheWEQIIDILWSDPRGKNGC-------FPNTCRGGGCYFGPDV
|. ....||     .| .|.                                       . .. |.|||||  ..|.       |.|. || |..||||.
ldqireier.....pleipd.......................................dgllldllwsdPweddgdgllrlrffgnsprgagylFgpda

TSKILNKYQLKMLIRSHECKPEGYEICHDGK------VVTIFSASNYYEEGSNRGAYIKLCSGTtPRFFQYQVTKATCFQPLRQRVDTMensAIKILRER
. ..|.|..|....|.|.. |||||...|||      ..|.|||.||. .| |..|.... ... . |.|.. .. . ..|| ..| ..   ....|.| 
veeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdpsphplilplfldvfll...slpfllek

VISRKSDLTRAFQLQDHRKSGKL
...  . |..... ... . ...
ltellllllnivsddellededi

PPP_5_Dcr2 167-406 1e-78 256.9 In-house 1-199 (199) alignment
Range on Protein: 167-406
Range on HMM: 1-199/199.0
VTICGDLHGKLDDLFLIFYKNG-LPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYklHGKRILQILE
||.||||||.||||.||..|.| .|||.. |||.||.|||||.|.|.|..|.   ||||...||.|||||| ..|..||||||.|.||  |||.|..||.
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlsky..hgkkiykils

EFYAWLPIGTIVDNEILVIHGGISETTDL-NLLHRVERnKMKSvlipPTETNRDHDTDskhnkvgvtfnahgriktngsptehlteheweqiidiLWSDP
... |||. ...|...||.|||.|..... .||...|| |...    |.|.....|..                                     |||||
dvfdwlPlaalidekvlvvhgglspeiksiellekier.kiei....peekgekadll.....................................lwsdp

R-GKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECK
|  ..||. |..||.|..||||||.|.|.|..||..|||||.|
rdaqegcklnseRGagllfgpdvtekfleknnlkliirshelk

PPP_2 167-406 1.2e-76 249.9 In-house 1-198 (198) alignment
Range on Protein: 167-406
Range on HMM: 1-198/198.0
VTICGDLHGKLDDLfLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILhkYKLHGKRILQILEE
||.||||||.|||| ||..||||||... |.|.||.|||||.|.|.|..|..  ||||...||.|||||. ..| .|||.||.|  .| .||.... |.|
vtvcGDlHGqldDL.lilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevl..kkkggkkvykklqe

FYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTdskhnkvgvtfnahgriktngsptehlteheweqiidilWSDPRG
....||.....|...||.|||.||...|   .. |..|..|.   .....  ..                                        .|||. 
vfelLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeek.......................................lsdpke

KNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECK
|.... |. ||.|..||||||...|.|..||..||.||.|
keellansarGagllfgpdvteelleknklkliiRaHevk

0049330 Metallo-dependent phosphatases 108-457 7.9e-76 248.1 In-house 4-302 (309) alignment
Range on Protein: 108-457
Range on HMM: 4-302/309.0
NGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQtspsKEVTICGDLHGKLDDLFLIFYKNGLPSErNPYVFNGDFVDRGK
 .|.| ..|.....|||.| .. ...|. ...|..|...|..||..||. ...      ....||.|| ||||  .. |.|.|.| . .||.||.|||| 
ldpllllelilslldllielllklkllseeellllllkakeilksepnllels....mrivviGDiHGqlddLlrllekigfppe.drlvflGDlvdrGp

NSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYklhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETT----DLNLLHRVERN
.|.|.| .|    | ||.. .| |||||. ..|  ||| .|.|.||   | .. . . .....||.  .....||..|||.|       ... |.|. . 
dslevlllllalkllypdnvfllrGNHElrllnglygfgdetlrky...gaelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerplei

KMKSvlipptetnrdhdtdskhnkvgvtfnahgriktngsptehlteheweQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSH
 . .                                                . |.|||||      |..  || |..||.... ..|.|..|...||.|
pldg...............................................llcdllwsdplpiregfapnprglgvvfghtaverflkkngldliirgh

ECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKAT
.. ..||....|||..|.|||.||... .|.||.... ......|....... .
gavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvpll

PPP_4 167-406 1.5e-75 246.6 In-house 1-197 (197) alignment
Range on Protein: 167-406
Range on HMM: 1-197/197.0
VTICGDLHGKLDDLFLIFYKNG-LPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKyklHGKRILQILE
||..||.||.||||.|...||| ||||.. |||.||.|||||.|.|.|..|.   ||||....|.|||||. ..||.|||.||.|.|   |||.||..|.
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek...hgkeilkklq

EFYAWLPIGTIVDNEILVIHGGISETTDLnlLHRVERNKMK--SvlipptetnRDHDT-----Dskhnkvgvtfnahgriktngsptehlteheweqiid
.....||. ...|...||.|||.|....   |...||.. |  |         . ...     .                                    
dvfdllplaalidekvlvvhgglsdeles..ldkierierkies.........pleeekrkdll....................................

iLWSDPR-GKNGcFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECK
 ||||||  ..| . |..||.|..||||||.|.|.|..||..|||||.|
.lwsdpreaqeg.lansvrGagllFgpdvtekfleknnlkliirshelk

0053225 Metallo-dependent phosphatases 115-453 1.3e-71 234.4 In-house 3-290 (293) alignment
Range on Protein: 115-453
Range on HMM: 3-290/293.0
PLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQtspsKEVTICGDLHGKLDDLFLIFYKNGLPSErNPYVFNGDFVDRGKNSIEILM
.|.....|||.| .. ...|.....|..|.|.|..||..||. ...      ....||.|| ||||  .. | |.|.| . .||.||.|||| .|.|.| 
slilllldllielllllkllseeelllllleakeilkkepnllels....mriyviGDiHGnlddLlallekigfppe.drlvflGDlvdrGpdslevle

ILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYklHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD-LNLLHRVERNKMKSvlippt
.|    |.||.. .| |||||. ..|  ||| .|.|.||  ..... . | .....||.  .....||..|||.|   . |. .....|  .        
lllalkllypdnvvllrGNHElmllnglygfgdetlrky..gaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplrip......

etnrdhdtdskhnkvgvtfnahgriktngsptehltehEWEQIIDILWSDPRGKNGCFPNtCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEIC
                                      ... . |.|||||.  .|. |.  || |..||.... ..|.|..|...||.|.. |.||...
......................................legllldllwsdpdlwsgwlps.yrglgvvfghtavlrflkkngldliirghqvvpdgylpw

HDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQV
.|||.||.|||.||... .|.||...| .|....|... .
fdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfap

subfamily_PPP5C_pd Subfamily PPP5C 103-304 4.3e-61 199.7 In-house 2-203 (322) alignment
Range on Protein: 103-304
Range on HMM: 2-203/322.0
VPDSYNGPRLQF-PLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGD
| |||.||.|.   .|   .. ||| ||.|. ||  |.|..| |.|..||..| ...|... .|..|.|||.||.  ||. || .||||||.|||.||||
vedsydgpkleeekitkefvkellelfkkqkklhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGd

FVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKlhgKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNL--LHR
|||||  |.|....|    |.|||...|.|||||   ||  |||. |. .||.   ....... | . |||.........||.|||. .. ...|  |..
fvdrGsfsveviltllgfkllyPnhfflsrGnhesdnmnklyGfegevkakyt...ekvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrk

VERNK
..||.
idrna

subfamily_PPP1C_pd Subfamily PPP1C 132-443 2.5e-59 193.8 In-house 8-268 (282) alignment
Range on Protein: 132-443
Range on HMM: 8-268/282.0
QILHAHYVLEVLFETKKVLKQMPNFTHIQtSPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNR
  |. . . ..| .....|.. | . ...  |   |.|.||.||.. ||  .| ..| |.|.| |.| ||.|||||.|.|....| .  . ||..|.| |
vklkeaeieallkkareillsqpillele.aP...vkivgdihGqyadllrlfetsgaPpesn.ylflGdyvdrGkqsletivlllaykikypenlfllr

GNHEDFMMNLRYGFTKEILHKYKLHgkrILQILEEFYAWLPIGTIVDNEILVIHGGisettdlnllhrvernkmksvlipptetnrdhdtdskhnkVGVT
||||.  .|  |||  |. ..|. .   . ... . ...||. ..||..||..|||                                        .  .
GnhesasinriyGfydeckrrysik...lWktftdvfnclPlaalvdekilcvhGG........................................lspe

FNAHGRIKTNGSPTEHLTEhewEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEG
..    |..   |.|  ..     ..|.|||||  ..  . .  ||    ||.|| .|.|.|..|....|.|..  .|||   . ..||.|||.|| .| 
lksleqirkiqrPlevpek...gllcdllWsdpdkevlgwsendrGvsftfgkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgef

SNRGAYIKLCSG
 | || ... . 
dnagavlsvdee

Metallophos Calcineurin-like phosphoesterase 167-407 2.7e-50 164.4 Pfam-A 3-200 (200) alignment
Range on Protein: 167-407
Range on HMM: 3-200/200.0
VTICGDLHGKLDDL---FLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMIL--CVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILH----------
....|||||.||||   .||..|.. ... ....|.||.||||..|.|.|..|  .| .| .|....|.|||||....| .|||..|.|.          
ilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglangee

---------------------KYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHrvernkmksvlipptetnrdhdtdskhnkvgv
                     .|.|.|... .  .|....||. ..||. ||..||..|....... .                                
eyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi................................

tfnahgriktngsptehlteheweqiidilwsdprgkngcfpntcrgGGCYFGPDVTSKILNKYQLKMLIRSHECKP
                                               |...||||...|.|.||......|.|..||
...............................................gselfgpdalekllekygvdlvlrGHtHkp

subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 130-303 1.2e-36 119.2 In-house 20-187 (298) alignment
Range on Protein: 130-303
Range on HMM: 20-187/298.0
EQQILHAHYVLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHL
  .... . | ... ..||..|. . .  ... |   ...|||.||.  ||. .| |.| | . | |.| ||.||||....|....| .  . |||.. |
ltkvikeedveklielakkifkkqkslvevda.p...ikvcGdihGqysdllrlfdkagfppdan.ylflGdyvdrGrqnlevivlllaykvkypnnffl

NRGNHEDFMMNLRYGFTKEILHKYKlhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISE-TTDLNLLHRVERN
 |||||  ..|  ||| .|. ..||    |. . ... ...||. ... . || .|||.|.  . |. |....| 
lrGnheceainrvyGfyeeckrryk..slrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrp

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 136-292 3.8e-35 114.2 In-house 12-160 (287) alignment
Range on Protein: 136-292
Range on HMM: 12-160/287.0
AHYVLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHE
 . .|||| .....|. .| . .... |   .||.||.||.||||. || . | ... . |.| ||.|||| .|.|. ..|    . ||. .|| |||||
dkdilevlekieeileplpallevea.p...itivGdihGqlddllrifnavGaapkvq.ylflGdyvdrGakslevslllfslkiaypkkvhllrGnhe

DFMMNLRYGFTKEILHKYKlhgKRILQILEEFYAWLPIGTIVDNEILVIHGGISETT
   .|  ||| .|. .|..   .|. .  .. .. ||. ..|.. || .|||||.  
vkkinklyGfkeelkrkrq...erlykqfndvfselplcarvskrilcmhGGispkl

subfamily_PPP4C_pd Subfamily PPP4C 120-301 1.8e-33 109.0 In-house 2-177 (288) alignment
Range on Protein: 120-301
Range on HMM: 2-177/288.0
DIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVS
|.|  .|  .. .... . | ..  .....| .  | ..... |   ||.|||.||.. ||  .|  .|   |.| |.| |||||||..|.| ...| . 
dldrqieklrrcelikeeevkalcakareilveesnvqrvds.p...vtvcgdihgqfydllelfkvggdvpetn.ylflgdfvdrgfysvetfllllal

FLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKlhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISET-TDLNLLHRVE
 . ||. ..| |||||   .   ||| .|.|.||     .. .   | . .|....|.|..|...|||.|   . |. .  ..
kvrypdritlirgnhesrqitqvygfydeclrkyg..sanvwryctevfdylslaaiidgkifcvhgglspsistldeirsid

subfamily_PPG1_pd Subfamily PPG1 122-291 1.3e-32 106.3 In-house 2-165 (300) alignment
Range on Protein: 122-291
Range on HMM: 2-165/300.0
DLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSpskeVTICGDLHGKLDDLFLIFYKNGlPSERNPYVFNGDFVDRGKNSIEILMILCVSFL
|  || ..  ..|    | |. .  |..| .  |  .|..     ||. ||.||.. |.. ||   | .     |.| ||.||||  |.| ...| |  |
decleklqkaellpevtvkeltdklkellvkesnvieirsp....vtvvgdvhgqfydvleifkigg.qvpdtnylflgdyvdrglysvetisllivlkl

VYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKlHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISET
 ||  ..| |||||   .   |||  | |.||     |. . | |.. .| . .|.|.|| ..|||.| .
rypsritllrgnhesrqitqvygfyteclrkyg.gnsrvwkylteifdylvlaaiideeiycvhgglsps

subfamily_PPP3C_pd Subfamily PPP3C 120-304 8.9e-32 103.4 In-house 27-204 (452) alignment
Range on Protein: 120-304
Range on HMM: 27-204/452.0
DIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVS
 ...| | |...  |... .|... |. |.||. ... .... |   .|..||.||.  ||. .|  .| |.. . |.| ||.||||  |||... |   
klevlkehflkegrleeeaalkiieeaakllkkektllevea.P...itviGdihGqfydllklfevgGdPastk.ylflGdyvdrGyfsiecvlylyal

FLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKlhgKRILQILEEFYAWLPIGTIVDNEILVIHGGIS-ETTDLNLLHRVERNK
 . ||. |.| |||||   .   . | .|. .||.   ... . . | .  ||. ...... | .|||.| | ..|. .....| |
kiaypstlfllrGnhecrhlteyftfkeeckikys...eevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfk

subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 126-292 2e-31 102.1 In-house 14-166 (290) alignment
Range on Protein: 126-292
Range on HMM: 14-166/290.0
EAFKEQQIlhahyvLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPN
.||....|      ||.| . ...|. .| . .... |   ..| ||.||.||.|.  | . | | . . ..| ||.|||| .|.|. ..|    . |..
dafsdkdi......leilekieeileplpallevea.p...ivivgdihgqldallryfdavgyppkvk.flflgdyvdrgakslevslllfcykirysk

DLHLNRGNHEDFMMNLRYGFTKEILHKyklHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETT
 .|| |||||   .|  ||| .|.  |    | |. .  .. .| |.. . |.. || .|||||.  
kvhllrgnhevrkvnrlygfkeelark...rgsrlwkqyqdvfaelslcarvgrkilcmhggisqki

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 131-303 4.2e-31 101.4 In-house 5-176 (284) alignment
Range on Protein: 131-303
Range on HMM: 5-176/284.0
QQILHAHYVLEVLFETKKVLKQMPNFTHIQTSpskeVTICGDLHGKLDDLFLIFYKNGLP-----SERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPN
|..|. . ..|. . ..... . .   .|..     |.|.||.||. .||  ..  || |     .. . |.| ||.||||  |||....|    |..|.
qkllkekelielcyrarelfwkeklkleieap....vkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpd

DLHLNRGNHEDFMMNLRYGFTKEILHKYKlhgKRILQILEEFYAWLPIGTIVDNEILVIHGGISET-TDLNLLHRVERN
 . | |||||   .| .||| .|  ..|    ... ....  .  .|. ..|.. |. .||||||   ||. |...|| 
kvfllrgnhesrpvnmqygfyleckkrys...ealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerp

subfamily_PPP5C_pd Subfamily PPP5C 354-461 2.2e-30 98.8 In-house 209-316 (322) alignment
Range on Protein: 354-461
Range on HMM: 209-316/322.0
EQIIDILWSDPRGKNGCFPnTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL-CSGTTPRFFQYQ
......|||||. .||  | . || |..||||||.| |.. .|...||||| | ||||. ||||..|.||| || .. .|.||.|.|  . ....| ...
gllvellwsdpqeanGrsp.skrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfe

VTKATCFQP
  .    .|
avehpdvkp

subfamily_PPPLV_pd Subfamily PPPLV 168-438 2.9e-30 98.6 In-house 27-273 (290) alignment
Range on Protein: 168-438
Range on HMM: 27-273/290.0
TICGDLHGKLDDLFL---IFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL
 . |||||   ||      ... |       ..| ||.||||. |.|..  |    ..||  ..| |||||   .   . .  |  .|.  . . . . .
yvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqesieykgegsfkfgdsleevweaf

EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLipptetnrdhdtdskhnkvgvtfnahgrIKTNGSPT--EHLTEHEWEQIIDILWS
 . . .||. ...|.... .|.|| ...  .      .. .. .                              . .|.|   . | .   |.  . | .
nnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlk............................ddidgaplaldilwsdpaedrdlslrg

DPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYeEGSNRGAYI
.  ...|  .|  || |. |. |   . |.. .|. ..|.|| | .|... ..|...|.||.|.|   .||  | |
elvlneGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssryc.Gssneaali

subfamily_PPP2C_pd Subfamily PPP2C 119-293 3.4e-30 98.2 In-house 2-169 (290) alignment
Range on Protein: 119-293
Range on HMM: 2-169/290.0
TDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGlPSERNPYVFNGDFVDRGKNSIEILMILCV
.|.| |.| .|| . |. . | |.  ..|..|..  |  .... |   ||.|||.||.. ||. .|   |  |    |.| ||.||||  |.| . .| .
kdldklieklkeckqleesevkelcekakeilskesnvqevkc.p...vtvcgdvhgqfhdllelfkigg.kspdtnylflgdyvdrgyysvetvtllva

SFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKlhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD
  . |.. . . |||||   .   |||  | | ||      . ... ... .||. ..||..|...|||.| . |
lkvrykeritilrgnhesrqitqvygfydeclrkyg..nanvwkyftdlfdylpltalvdeqifclhgglspsid

subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 141-292 1.6e-29 95.9 In-house 13-156 (280) alignment
Range on Protein: 141-292
Range on HMM: 13-156/280.0
EVLFETKKVLKQMPNFTHIQTSpskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN
.|. . ||.|.    .  ...     |..||||||.  ||. .| . ..| ..| |.| ||.||||.  .|....|    . |||.. . |||||   .|
rviekckkiltaqatmvevdap....vavcgdlhgqytdllrlfarvsfppdqn.ylflgdyvdrgrqqlevillllaykvrypnnflilrgnhevisin

LRYGFTKEILHKYKLHgkrILQILEEFYAWLPIGTIVDNEILVIHGGISETT
 .|||  |. ..|.|.   . . ..|..  ||. ..|   ||..|||.|.  
rkygfkdevkrrysla...lynefqelldslplvalvsgrilcmhgglsqkl

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 165-302 2.9e-29 95.3 In-house 51-186 (299) alignment
Range on Protein: 165-302
Range on HMM: 51-186/299.0
KEVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKlhGKRILQIL
  . .|||.||.  ||. || |.|.| . | ..| ||.||||.. .|....| .  . ||..... |||||   .|  ||| .|  ..||    |.  |.
apiivcgdihgqysdllrifdkagfppdvn.flflgdyvdrgrqnlelitlllcfkikyperffmlrgnhecpainrvygfyeecnkryk..strlwsif

EEFYAWLPIGTIVDNEILVIHGGISET-TDLNLLHRVER
.. .|..|.  .. . ||..|||.|   ..|. |  . |
qdafaampltgligsrilcmhgglspklqtldqlrdltr

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 138-302 4e-29 94.9 In-house 27-188 (297) alignment
Range on Protein: 138-302
Range on HMM: 27-188/297.0
YVLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDF
 ||..|  . .|.|.  ..  ... |   . .|||.||.. ||. .|.. | |   | |.| ||.||||. ||| ...|    . .| .| | |||||  
rvlklldlaldvfkaqksmvevna.p...ikvcgdihgqfpdllrlfhrggwpptan.ylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnhece

MMNLRYGFTKEILHKYKlhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISE--T--TDLNLLHRVER
..|  ||| .|  ..|.    |.   ... . |||.  .. ..||..|||.|   |    |. |...||
fvnkvygfyeecqkryq..svrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkier

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 139-291 5.3e-29 94.5 In-house 8-153 (284) alignment
Range on Protein: 139-291
Range on HMM: 8-153/284.0
VLEVLFETKKVLKQMPNFTHIQtSPskeVTICGDLHGKLDDLFLIFYKNGLPSeRNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM
|  .||.. ..... | .  .. ||   . ||||.||.. ||. .| |||.|  |  |.| ||.|||||  .| ...|    ...|| . . |||||  .
vetllfhafsifnkqpmlievn.sp...inicgdihgqfsdllrlfdkngfph.ranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecsl

MNLRYGFTKEILHKYKLhgKRILQILEEFYAWLPIGTIVDNEILVIHGGISET
.|  ||| .|  ..|.     . . .|  .. .|. ..| . ||..|||.|. 
inkiygfyeecqrrynk..psvyvsfegvfsvmpltalvgqrilcmhggvskm

subfamily_PPP6C_pd Subfamily PPP6C 153-303 2.9e-28 91.8 In-house 31-178 (290) alignment
Range on Protein: 153-303
Range on HMM: 31-178/290.0
MPNFTHIQTSpSKEVTICGDLHGKLDDLFLIFYKNGLPSERnPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHK
. . . .|.  |  ||.|||.||.. ||  .| . |   .   ||| |||||||  |.| .  | .  . ||. . | |||||   .   ||| .| |.|
lleesnvqpv.sspvtvcgdihgqfydleelfrtggqvpdt.syvflgdfvdrgyysletftrlltlkakypdritllrgnhesrqitqvygfydeclnk

YKLhgKRILQILEEFYAWLPIGTIVDNEILVIHGGISET-TDLNLLHRVERN
|        . . . .  |.|..|.|...| .|||.|   . |. .. .||.
ygn..anawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirviera

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 139-292 2.4e-25 82.3 In-house 11-171 (302) alignment
Range on Protein: 139-292
Range on HMM: 11-171/302.0
VLEVLFETKKVLKQMPNFTHIqtspSKEVTICGDLHGKLDDLFLIFYKN----------GLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH
.| .. .  . ||.  ....|    |  ||| ||.||. .||. |. ..               .. .|| ||.||||..||| . ..    ..||..  
llllieaviellkkektlaei....spPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyi

LNRGNHEDFMMNLRYGFTKEILHKY-KLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETT
| |||||   .|  ||| .|.  .. | .||.| . ..| ....|. ..| . || .|||||.  
llrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispkl

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 139-292 3e-25 82.0 In-house 12-172 (302) alignment
Range on Protein: 139-292
Range on HMM: 12-172/302.0
VLEVLFETKKVLKQMPNFTHIqtspSKEVTICGDLHGKLDDLFLIFYKN----------GLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLH
.| .. .  . ||.  ....|    |  ||| ||.||. .||. |. ..               .. .|| ||.||||..||| . ..    ..||..  
llllieaviellkkektlaei....spPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptnyi

LNRGNHEDFMMNLRYGFTKEILHKY-KLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETT
| |||||   .|  ||| .|.  .. | .||.| . ..| ....|. ..| . || .|||||.  
llrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispkl

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 167-291 5.9e-25 81.4 In-house 9-134 (263) alignment
Range on Protein: 167-291
Range on HMM: 9-134/263.0
VTICGDLHGKLDDLFLIFYKNGLpSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHG--KRILQIL
. |||| ||. .||. ||   |  . .  |.| ||.||||  |.|..|.|    |  |  .|| |||||   .|  |||  |. ....     . . . .
inicgdthgqyndllrifnacga.atktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevyesvynhf

EEFYAWLPIGTIVDNEILVIHGGISET
.. ....|. .|| . ||..|||||  
nqvfsymplcaivskrilcmhggisph

subfamily_PPZ_pd Subfamily PPZ 135-291 1.4e-24 80.2 In-house 26-174 (300) alignment
Range on Protein: 135-291
Range on HMM: 26-174/300.0
HAHYVLEVLFETKKVLKQMPNFthIQTSPSkeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNH
.   .|.. .......   |..  .. |||  | | ||.||.  ||. .| | |.|   | |.| ||.|||||.|.| ...| .  . ||... | ||||
knseilqicikarelflaqpal..lelsps..vkivgdvhgqyadllrlftkcgfppsan.ylflgdyvdrgkqsletillllcykikypenffllrgnh

EDFMMNLRYGFTKEILHKYKLhgkRILQILEEFYAWLPIGTIVDNEILVIHGGISET
|   .   |||  |  .. ..   .| . . . .  ||. .||  .|...|||.|  
ecanvtrvygfydeckrrcni...kiwktfvdtfntlplaaivagkifcvhgglspv

subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 137-295 1.4e-24 79.8 In-house 11-162 (281) alignment
Range on Protein: 137-295
Range on HMM: 11-162/281.0
HYVLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHED
. . .|..|.. .. .  ... |.. |   ... ||||.. .||  .|   | ..|.  .|| ||.||||..|.|.|..| .  . |.. . | ||||| 
eeienvireveaifseekaLveidk.P...ivvvGdlhaqfndlkrlfellgrvpeev.lvflgdyvdrgpqslevlillftlkiryrdrivllrgnhei

FMMNLRYGFTKEILHKYklhGKRILQILEEFYAWLPIGTIVDNEILVIHGGISE-TTDLN
  .| .||| .|   ||   |. .   ... .  ||| . ... .|..|||.|   | |.
asvnkiygfyvecvtky...GeelwalfqrcfnrlpisaliakrvlcmhGGlsPeltald

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 194-303 3e-24 78.8 In-house 101-208 (317) alignment
Range on Protein: 194-303
Range on HMM: 101-208/317.0
NPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKlhgKRILQILEEFYAWLPIGTIVDNEILVIHGGISET-T
. |.| ||.||||  |||....|    |.||. ..| |||||   .| .||| .|. ..|.   ... ....  .  ||. ..|...|| .||||||  .
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkrys...aalyeafqlafnvlplcavvnkkilcmhGGiseell

DLNLLHRVERN
||. |....| 
dlkqldklkrp

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 167-291 4.4e-24 78.2 In-house 49-172 (307) alignment
Range on Protein: 167-291
Range on HMM: 49-172/307.0
VTICGDLHGKLDDLFLIFYKNGLPSERnPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEE
. . |||||...||  .|   | | |   ||| ||.||||  |.|....| .  ..||... | |||||   .| .||| .| .      |. |  ... 
cvvvgdlhgqfndlinmfillgrppet.vyvftgdyvdrgllslecilllftykicypenivllrgnheiarvnkkygfyeecvtsipkcgeeiwalfqr

FYAWLPIGTIVDNEILVIHGGISET
 .  ||| ...   ||..|||.| .
cfnnlpisaliatkilcmhgglspa

subfamily_PPP2C_pd Subfamily PPP2C 355-453 3.6e-20 65.3 In-house 188-285 (290) alignment
Range on Protein: 355-453
Range on HMM: 188-285/290.0
QIIDILWSDPRGKNGcFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQV
 . |.|||||  ..| .  . || |  || |.. |. .. .|....|.|.   |||. .|| .||||||| ||     |..| ..|    . .| |.. 
plcdllwsdpddrgg.wgisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdp

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 195-292 1.6e-19 63.2 In-house 121-216 (339) alignment
Range on Protein: 195-292
Range on HMM: 121-216/339.0
PYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLhgkRILQILEEFYAWLPIGTIVDNEILVIHGGISET-T
 |.| ||.||||  |.|....|    | ||. ..| |||||   .|  ||| .|. ..|     .. . .....  .|. ....| |...||||||  |
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyryda...qlyecfqnmfnvfpfcavinntimcmhggisehlt

subfamily_Cele-PPP-Subfam4_pd Subfamily Cele-PPP-Subfam4 355-440 7.2e-18 57.6 In-house 195-280 (298) alignment
Range on Protein: 355-440
Range on HMM: 195-280/298.0
QIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL
  ||.||.||  .   . .  || .. || ||  ..|.| .. ...|.|    .|||   . |.|||||| .| ..  |  | .|.
laidllwadpenavkgwaensrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkv

subfamily_Cele-PPP-Subfam3_pd Subfamily Cele-PPP-Subfam3 331-442 1.7e-17 56.3 In-house 159-270 (287) alignment
Range on Protein: 331-442
Range on HMM: 159-270/287.0
TFNAHGRIKTNGSPTEHLTEHEwEQIIDILWSDPRGK-NGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYE
  ..   .|.   || .|. .|   ..|.||.||  . ..  .|  |.    ||  .  ..|.| ......|.|| . |||.   | ..||.|||. |  
klksldslkalkkpttplacde.glqvdllwadpekdaktfelnkiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysg

EGSNRGAYIKLCS
| .| || ...  
edtnlgavvvvsk

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 356-439 2.5e-17 56.0 In-house 217-300 (317) alignment
Range on Protein: 356-439
Range on HMM: 217-300/317.0
IIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIK
. |. |.||  .   . .. || |  ||..   . |.|..|....|.|.   .|||   | |.|||||| .|  .  | .| ..
ladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavls

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 166-295 6.8e-17 54.8 In-house 34-160 (280) alignment
Range on Protein: 166-295
Range on HMM: 34-160/280.0
EVTICGDLHGKLDDLFLIFYKNGLPSERNpYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHgkrILQILE
 . . ||.| . .|.  .|   |   | .  .| ||.|||| . ||.|..| .  . | . ..| |||||   .|  |||  |. .|| .    .   ..
pikvigdihaqyqdmnrlfdligrvpeek.lmflgdyvdrgpqgievlillfclkiryrdriyllrgnhetpsvnkiygfyvecqykygvg...lwwdfq

EFYAWLPIGTIVDNEILVIHGGISE-TTDLN
  .  .|.  .. . .|..|||.|    .|.
scfnrmpmsgliskrvlcmhgglspelinld

subfamily_PPP4C_pd Subfamily PPP4C 355-448 1.1e-15 50.6 In-house 187-279 (288) alignment
Range on Protein: 355-448
Range on HMM: 187-279/288.0
QIIDILWSDPRGKNgCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRF
...|.|||||. .. ..  . || |  || ||...  .. ......|.|.   |||    . ||.|..|| ||     |  | ..| . .  .|
plcdllwsdpedae.gwavsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdf

subfamily_Cele-PPP-1A_pd Subfamily Cele-PPP-1A 356-440 2.3e-15 49.8 In-house 185-269 (284) alignment
Range on Protein: 356-440
Range on HMM: 185-269/284.0
IIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL
| |. |.||  .   . .. || |  ||..   ..|.|..|....|.|.   .|||.  | |.||||||  |  .  | .| ...
iadltwadpeaevegykesprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnv

subfamily_Cele-PPP-4D_pd Subfamily Cele-PPP-4D 350-438 4.2e-15 48.8 In-house 191-279 (297) alignment
Range on Protein: 350-438
Range on HMM: 191-279/297.0
EHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYI
| . . . |.||.||      | .  || || || |   |.  ...| .. |.|.   .|||.    |.||||||  |  .  |  |..
egkerlvadllwadpisglsgfmenqrgagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafm

subfamily_Cele-PPP-3B_pd Subfamily Cele-PPP-3B 332-441 4.7e-15 48.4 In-house 166-276 (290) alignment
Range on Protein: 332-441
Range on HMM: 166-276/290.0
FNAHGRIKTNGSPTEHLTEHEwEQIIDILWSDPRG-KN-GCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYE
 ..   .|.   |  .|| .|   ..|.||.||   |.     |  |.    || ..  ..|.|  |....|.|| | ||...  | |.||.|||  |  
iesweslkalkkprvpltcde.glqvdllwadptrdkddtialnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysg

EGSNRGAYIKLC
. .| || ... 
ndtnlgaiatvs

EF-hand_7 EF-hand domain pair 574-635 7e-15 44.8 Pfam-A 5-66 (66) alignment
Range on Protein: 574-635
Range on HMM: 5-66/66.0
IFNAIDTDHSGLISVEEFRAMWKLFSSHYNvhidDSQVNKL----ANIMDLNKDGSIDFNEFLKAF
.|...|.|..| ...||.... | ..|.      |..| .      . .|.|.|| ..|.|||.|.
aFkllDkdgdgyldkeeLlrllkhlgspli....deevrevldyifkeiDkngdGvlsfeEflqai

subfamily_Cele-PPP-4C_pd Subfamily Cele-PPP-4C 357-440 7.3e-15 47.8 In-house 178-261 (280) alignment
Range on Protein: 357-440
Range on HMM: 178-261/280.0
IDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL
 |.||.||  |   . .. ||    || .|  .. .| .. ...| |.   .|||.  | |.||.||| .| .| .|  | ...
mdllwadpenkvtgwaensrgvsvifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavliv

subfamily_Cele-PPP-Subfam2_pd Subfamily Cele-PPP-Subfam2 354-440 2e-14 46.5 In-house 177-263 (281) alignment
Range on Protein: 354-440
Range on HMM: 177-263/281.0
EQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL
  .||.||.||  |   . .. || .  || .|  ..  . .. ..||.|    .|||.    |..|.||. || .   | .| .|.
GlviDllwadpdnkveewkassrGssftfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkv

subfamily_PPG1_pd Subfamily PPG1 356-450 7e-14 44.8 In-house 187-292 (300) alignment
Range on Protein: 356-450
Range on HMM: 187-292/300.0
IIDILWSDPR----------GKNG-CFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGT
. |.|||||            ..|  | .. || |  .| ||. |.|.. ... .||.|.   |||.|  |.|. |..|| || .   |. . ..| .  
ladllwsdpeennnptldhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekd

TPRFFQ
   |  
eryfnv

subfamily_PPP6C_pd Subfamily PPP6C 355-440 1e-13 44.1 In-house 186-270 (290) alignment
Range on Protein: 355-440
Range on HMM: 186-270/290.0
QIIDILWSDPRGKNgCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL
 . |..||||   .  .  . || |  ||  ||.....  .||...|.|.   ||..   | |.||..|| ||     |  . ..|
afcdlvwsdpedve.twavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilal

subfamily_Cele-PPP-4A_pd Subfamily Cele-PPP-4A 356-436 1.2e-13 44.1 In-house 176-256 (284) alignment
Range on Protein: 356-436
Range on HMM: 176-256/284.0
IIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGA
 ||||||||   .  .    ||    || |   |.|.. |. ...|.|.   .|||.  . ..||||||  |  .  |  |
aidilwsdptnfqkgwnpnsrgvsyvfgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaa

subfamily_PPP3C_pd Subfamily PPP3C 355-442 1.5e-13 43.4 In-house 211-311 (452) alignment
Range on Protein: 355-442
Range on HMM: 211-311/452.0
QIIDILWSDPRG-------KNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHD------GKVVTIFSASNYYEEGSNRGAYIKLC
 . |.|||||         ..   ||. ||  ....   ... |.| .|  .||.||.. .||.  ..        ..|.|||.|| .  .|..| .|. 
plcdllWsdPledygeekteekfvpnsvrGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkye

S
.
n

subfamily_Cele-PPP-1B_pd Subfamily Cele-PPP-1B 356-436 1.9e-13 43.2 In-house 236-316 (339) alignment
Range on Protein: 356-436
Range on HMM: 236-316/339.0
IIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGA
. |. |.||   .  .  ..||    |||     .|.| .|.|.|| |.   .|||.    ..|||||| ||  .  |  |
ltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaa

subfamily_Cele-PPP-4B_pd Subfamily Cele-PPP-4B 357-453 3.2e-13 42.6 In-house 197-293 (299) alignment
Range on Protein: 357-453
Range on HMM: 197-293/299.0
IDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQV
||.||.||      . .  ||    ||.|| ...... .. .. |.|.   .|||.  . |.||||||  |  .  |  | .|.       |  .. 
idllwadpdqsvkdwlanvrgvsyvfgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkp

subfamily_PPZ_pd Subfamily PPZ 351-444 3.5e-13 42.7 In-house 191-284 (300) alignment
Range on Protein: 351-444
Range on HMM: 191-284/300.0
HEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGT
 ..  | |.|||||   .  . .  ||    .      |.|||. . .. |.|    .|||.  |  .||.||| ||  |  | || . .. | 
pdfglindllwsdptdssnewednergvsycynkvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegl

PPP5 PPP5 TPR repeat region 92-158 1.2e-12 38.1 Pfam-A 28-94 (95) alignment
Range on Protein: 92-158
Range on HMM: 28-94/95.0
RDRWDyVDSIDVPDSYNGPRLQ-FPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTH
 .  | ..||.. |.|.||||.   .| . .. ||| ||.|. || ..| ..| ..|..||..|.. .
aesid.iesieieddYdgprledekvtlefvkelleefkkqkklhkkfvyqilldvkellkklpslve

subfamily_Cele-PPP-5_pd Subfamily Cele-PPP-5 370-440 3.3e-12 39.2 In-house 216-286 (302) alignment
Range on Protein: 370-440
Range on HMM: 216-286/302.0
CFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL
   |. ||    |      .. ....||...|.|   |||.    | |..|||||..| .|  |.|| .|.
yaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkv

subfamily_Cele-PPP-Subfam5_pd Subfamily Cele-PPP-Subfam5 370-440 3.7e-12 39.1 In-house 217-287 (302) alignment
Range on Protein: 370-440
Range on HMM: 217-287/302.0
CFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL
   |. ||    |      .. ....||...|.|   |||.    | |..|||||..| .|  |.|| .|.
yaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkv

subfamily_Cele-PPP-2B_pd Subfamily Cele-PPP-2B 354-441 8.6e-12 38.1 In-house 175-262 (280) alignment
Range on Protein: 354-441
Range on HMM: 175-262/280.0
EQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLC
  .||.|||||  |   .  . ||    ||  |  .  .  .. ..||.|.   .|||.    ...|.||  ||  . .|  | . | 
gllidllwsdptnkgegwfhsirgisymfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvcln

subfamily_Cele-PPP-2A_pd Subfamily Cele-PPP-2A 357-440 7.6e-10 31.4 In-house 195-278 (307) alignment
Range on Protein: 357-440
Range on HMM: 195-278/307.0
IDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL
 |.||.||      .  . || |  || .|   . ..  ....||.|.   .|| .    |..|||||  | .   | |. .|.
ndmlwadpdpsvfewkassrgsgftfgtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkv

EF-hand_1 EF hand 571-597 1.6e-09 26.4 Pfam-A 2-28 (29) alignment
Range on Protein: 571-597
Range on HMM: 2-28/29.0
LEIIFNAIDTDHSGLISVEEFRAMWKL
|. .|. .|.|..| ||.|||....| 
lkeaFkefDkDgdGkIsfeEfkealkk

EF-hand_8 EF-hand domain pair 570-596 4.5e-09 25.1 Pfam-A 26-52 (54) alignment
Range on Protein: 570-596
Range on HMM: 26-52/54.0
DLEIIFNAIDTDHSGLISVEEFRAMWK
...|.|...|||..| || ||| ....
evdilfrefDtdgdGkisfeEFcvlle

subfamily_Cele-PPP-3A_pd Subfamily Cele-PPP-3A 354-438 9e-09 28.3 In-house 155-240 (263) alignment
Range on Protein: 354-438
Range on HMM: 155-240/263.0
EQIIDILWSDPRGK-NGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYI
    |.||.||    .|  ||  |     ||      . .. .. ...|.|.    || .  | ...|.|||| |  |  |  | .
placdllwadpekdakgfepnkiraisnvfgkkevddlckrldidlivrahqvveygyaffadrrlitvfsasryqielcnyaavv

EF-hand_5 EF hand 572-594 2.5e-08 22.3 Pfam-A 2-24 (25) alignment
Range on Protein: 572-594
Range on HMM: 2-24/25.0
EIIFNAIDTDHSGLISVEEFRAM
. .|.|.|.. .| || ||....
kdtFrafDkNgDGkIsreELkrl

EF-hand_8 EF-hand domain pair 606-635 1.1e-07 20.7 Pfam-A 22-51 (54) alignment
Range on Protein: 606-635
Range on HMM: 22-51/54.0
IDDSQVNKLANIMDLNKDGSIDFNEFLKAF
. ...|  | . .|...|| |.|.||....
lseeevdilfrefDtdgdGkisfeEFcvll

EF-hand_1 EF hand 612-635 1.2e-07 20.5 Pfam-A 3-26 (29) alignment
Range on Protein: 612-635
Range on HMM: 3-26/29.0
NKLANIMDLNKDGSIDFNEFLKAF
... ...| ..|| |.|.||..|.
keaFkefDkDgdGkIsfeEfkeal

IQ IQ calmodulin-binding motif 18-35 2.3e-07 19.7 Pfam-A 2-19 (21) alignment
Range on Protein: 18-35
Range on HMM: 2-19/21.0
RAALIIQNWYRGYKARLK
.||..|| ..|||.|| .
kaaikIQaawRgylaRkr

subfamily_YNL217W_pd Subfamily YNL217W 162-311 3.9e-07 22.8 In-house 7-159 (235) alignment
Range on Protein: 162-311
Range on HMM: 7-159/235.0
SPSKEVTICGDLHGKLDDLFLIFY-KNGLPSERNPYVFNGDFVDRGKNSIEILMILcvsflvYPNDLHLNRGNHEDFMMN-LRY-----GFTKE-ILHKY
  .|.. . || ||  |.|  ..  |.|   |    |. ||....| .|.|..  .        .. .  .||||  ..  ...     |...     |.
vlgkrllvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvllaykwvkkpkgaeplefsskf

KLHGKRILQILEEFYAWLPIG-TIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIP
.   ... .   |..  |.    |  .|.||.|.|..    |.  .. |  ... .|. 
sflesklskadmeyarelgfsldipsdellvvhaGlvpgkfleensidevlslrnllvd

EF-hand_6 EF-hand domain 574-596 9.6e-07 18.3 Pfam-A 5-27 (31) alignment
Range on Protein: 574-596
Range on HMM: 5-27/31.0
IFNAIDTDHSGLISVEEFRAMWK
.|...|.|..| |. ||.|.. .
aFklfDkdgdGkidaeELrkaLr

EF-hand_5 EF hand 617-633 1.7e-06 16.5 Pfam-A 7-23 (25) alignment
Range on Protein: 617-633
Range on HMM: 7-23/25.0
IMDLNKDGSIDFNEFLK
 .|.|.|| |.. |. .
afDkNgDGkIsreELkr

subfamily_Cele-PPP-Subfam1_pd Subfamily Cele-PPP-Subfam1 131-191 5.7e-06 18.7 In-house 6-62 (317) alignment
Range on Protein: 131-191
Range on HMM: 6-62/317.0
QQILHAHYVLEVLFETKKVLKQMPNFTHIQTsPskeVTICGDLHGKLDDLFLIFYKNGLPS
|...... ..|. . ..... . | . .... |   |||.||.||. .||  ..  || | 
qdlfkekelielcyrarelfwkeplklelea.p...vtivGdihGqfedllalldlnGwpl