Gene ACP2 in Homo sapiens

Synonym: LAP, ACP2

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily ACP2
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP158_AA protein Get Run
HsapP158_AA_23-374 phosphatase_domain Get Run
Domains
Summary
100200300400MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLRFVTLLYRHGDRSPVKTYPKDPYQEEEWPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESSRNAQFLDMVANETGLTDLTLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLPKLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQEDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPGYRHVADGEDHAHP2Curated phosphatase domainHis_Phos_2Pfam Domainsubfamily_ACP2_pd(1)0053031(2)0049226(3)0046349(4)0049059(5)SubfamilyTransmembrane regionSignal peptide cleavage site
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP2_pd Subfamily ACP2 29-373 1.2e-126 415.0 In-house 5-359 (361) alignment
0053031 Phosphoglycerate mutase-like 33-370 5.2e-105 344.3 In-house 3-340 (342) alignment
0049226 Phosphoglycerate mutase-like 33-370 1.6e-104 342.7 In-house 3-340 (342) alignment
0046349 Phosphoglycerate mutase-like 32-372 3.9e-97 318.8 In-house 6-392 (409) alignment
0049059 Phosphoglycerate mutase-like 30-371 3.4e-96 315.7 In-house 40-435 (435) alignment
0048946 Phosphoglycerate mutase-like 30-374 7.1e-96 314.7 In-house 38-413 (447) alignment
0047369 Phosphoglycerate mutase-like 24-371 4.1e-94 309.1 In-house 35-437 (438) alignment
0048439 Phosphoglycerate mutase-like 31-363 1.4e-90 297.3 In-house 7-391 (391) alignment
His_Phos_2 Histidine phosphatase superfamily (branch 2) 33-329 6.1e-64 209.1 Pfam-A 2-346 (347) alignment
His_Phos_2 Histidine phosphatase superfamily (branch 2) 33-329 6.1e-64 209.1 In-house 2-346 (347) alignment
subfamily_ACP6_pd Subfamily ACP6 65-373 3.8e-42 136.3 In-house 75-374 (376) alignment
subfamily_PXYLP1_pd Subfamily PXYLP1 65-321 4.3e-21 66.6 In-house 103-357 (419) alignment
subfamily_HP2-Group1_pd Subfamily HP2-Group1 199-372 3.6e-16 50.5 In-house 244-418 (422) alignment
subfamily_HP2-Group1_pd Subfamily HP2-Group1 65-131 1.7e-13 41.7 In-house 92-160 (422) alignment
subfamily_MINPP1_pd Subfamily MINPP1 66-214 1.6e-11 35.7 In-house 90-240 (420) alignment