Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_ACP2_pd | Subfamily ACP2 | 33-376 | 6.8e-120 | 392.9 | In-house | 7-360 (361) | alignment | ||
Range on Protein: 33-376
Range on HMM: 7-360/361.0
KELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRY-R--KFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGV
..||||...|||||||| .|.|.|..||..||||.||||..||.|.||||...|||| . |||...|...|.|.||.||.||||||...||.|||||.
rkLkfvqvlfRHGdRsPlntypndkykedewpqglGqLTeeGmqqqyeLGkfLrkrYvedtkfldakynpkqiyvrSsdvnRTlmSaqsvlaglfppetg
SIWNPILLWQPIPVHTVPLSEDQLLYlPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGlHGQDLFGIWSkVYDPLYCESV-HN-FTLPSWA
... |||.|||||. .||.|| ...||||..|| .|. .|.|..| |. .|... .| . .| . ||. .. ..| |.|| .| ..||.||
vdypdeqeWqpvPvhtvseeedlllr.akknCprydellqeakespevkklleenkelleklsestg.edidlenfyq.lsdtlicerkyanelnlpewa
TEDTMTKLRELSELSLLSLYG--IHKQKEKSRLQGGVLVNEILNHMKRATQ---IPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYF-E
......||.||.. . .| .|..|...|.||.|.||.|..||.... .. .||..|||||||. | .||..... |||||. . ||| .
ndelfekleeladkvkeaefglnnektrelkklrgGpllnellenmkeklkceekkkklklflYSaHDttlaalLeaLgifekkappyasaiivElyeed
KGEYFVEMYYRNETQHEPYPLMLPGC--SPSCPLERFAELVGPVIPQDWSTECMTTN
.|...|...|||||...|. | |||| . |||..| ..| |.||.|....| ...
dgkplvkvlyrnetskdppeltlpgCkgeedCplskfkkivkpfipddvdelCeakt
|
|||||||||
0049226 | Phosphoglycerate mutase-like | 34-372 | 3.4e-110 | 361.3 | In-house | 2-340 (342) | alignment | ||
Range on Protein: 34-372
Range on HMM: 2-340/342.0
ELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWN
.||.| ...|||||.|....| |...| |. |.|.||.||.||.||||...|||| ..|.. |....||.||.||||||.||. ||.|||||. .|..
kLkqvqvliRHGdRtPlakgpldflnewfwgcglgeLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSaqaflaGlfppeltpilv
PILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMT
| | |||||..|.| | |.||.||. .||.|..| .|.|||||.|. |....|.. .| || || .| ... .|| |..|..|...||.| ...|.
plldwqpipiitepesndtllllpydscpnfdkllkellkseevqlfleeildllkklskllglnlstlsdvadtlydlllyelahglplppwcslftle
KLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRN
.|..|..|.|| .||| | .||.||.|.||||.....|.. || ||..|.|||||. | .||..... ||||||. .||| .|||.|...|..
elkalyaldllyyygigygeeiarlaggpllneilarleeaiegpsdlklylyfahdttiaallsalglfddqlPpyasnlvfElyecdgeyyVrvlyng
ETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTEC
.. ..|..| ||||. |||..| |||....|.|. ..|
gvlslpvtlplpgcdglcpldefkelvkkflpgdfeelC
|
|||||||||
0053031 | Phosphoglycerate mutase-like | 34-372 | 3.8e-110 | 361.2 | In-house | 2-340 (342) | alignment | ||
Range on Protein: 34-372
Range on HMM: 2-340/342.0
ELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWN
|||.| ...|||.|.|....| ||..| .| |.|.||.||.||.||||...|||| ..|.. |....||.||.||||||.||. ||.|||||| .|.|
eLkqvivlvRHGaRtPlskgpldplnewfypcgageLTplGreqayelGrrlrkrYlgllpstynpdevyvrssdvdRtlqSAqaflaGlfppegtpiln
PILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMT
|.| |||||.||.| |.|.||.... .||.|..| .|.|.|||....|..|......| | ||. ||. ..| .|| |..| .|...||.| |..|.
pllgwqpipihtepessdalllpnydpcpafdkllkealaseevkellerylellqklskglgltlsdlldlvsdlydlllyelahglplppwctlftle
KLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRN
.|. |..|.|| .||. . | ..|.||.|.||||........ |. ||..|.|||||. | .||..... ||||||. .||| .|||.|...|..
elkalyaldllyyyglgpgnelaklaggpllneilarleekisgpldlklylyfahdttiaallsaLglfddqlPpyasnlvfElyedpgeyyVrvlyng
ETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTEC
.| .||..| ||||. .|||..| ||| ...|.|. ..|
gtlseplvlplpgcdglcplsefkelvkkllpgdfeklC
|
|||||||||
0046349 | Phosphoglycerate mutase-like | 34-377 | 1e-96 | 317.5 | In-house | 6-395 (409) | alignment | ||
Range on Protein: 34-377
Range on HMM: 6-395/409.0
ELKFVTLVFRHGDRSP---IDTFPTDPIKESS-WPQGFGQLTQLGMEQHYELGEYIRKRY--RKFLNES--YKHEQVYIRSTDVDRTLMSAMTNLAALFP
|||.| ..||||.|.| ...| .| . .| |.||||.||.||.||||...|||| ..|... |.....|.||.||||||.||. .||.|||
eLkqvqvlfRHGaRtPtkklsflpnwpginwtngpcgagqLTplGreqayelGkrlrkrYvdlgLlpsnslynpdeiyvrssdvdRtlqSAqaflaGlfp
PEGVSIW------NPILLWQPIPVHTVPLSE----DQLLYLPFRNCPRFQELESETLKS-EEFQK-----------RLHPYKDFIATLGKLS-----GLH
|.|..|. .. ...||||..|||.|| | |. |. .||....| .|.||| .|... |. .||.. .| . ||.
plggeivpllrqdlldppfqpipidtvpiseddalddtllppdslcpaldkllkenlkslsevleflvdealldlelldetkdllkklaerlnselpgln
GQDLFGIWSKVYDPLYCESVHNFTLPSW---ATEDTMTKLRELSELSLLSLYGIhkqKEKSRLQGGVLVNEILNHMKRATQIPS------YKKLIMYSAH
|.. ..| .|| |..| .|...||.| |.. . .|..|. |. ||| .| ..|.||.|.||||.....|.. . ||..|.||
ltdpldvasllydtllyetahglplppwcdlftpeelkvlayladleyyylygs...gelaklaggpllneilarledaisgknpvtfpldlklylyfaH
DTTVSGLQMALDVYN-----GLLPPYASCHLTELYF--EKGEYFVEMYYRNEtqhepyPLMLPGCSPSCPLERFAELVGPVIPQ----DWSTECMTTNS
|||. | .||.... .|||||. .||| ..|||.|...|... || ||||.. |||..| ||. ...|. |. ..| ...
dttiaallsaLglfdrlfrssdippyasnlvfElyecpsdgeyyVrvlyngg......plplpgcgegcplsefkellkkrlpgcgltdfdklCpledf
|
|||||||||
0049059 | Phosphoglycerate mutase-like | 33-372 | 4.5e-94 | 308.7 | In-house | 41-434 (435) | alignment | ||
Range on Protein: 33-372
Range on HMM: 41-434/435.0
KELKFVTLVFRHGDRSPID-----------------TFPTDPI---KESSWPQGFGQLTQLGMEQHYELGEYIRKRYrKFLnesYKHEQVYIRSTDVDRT
|||.| ..||||.|.|.. |.|..|. .. .|.|.|.||.||.||.||||...|||| .|| |....||.||.|||||
celkqvqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrY.gfL...ynpdevyvrssdvdRt
LMSAMTNLAALFPPE--GVSIWNPILLWQPIPVHTVPLSEDQLlylPFRNCPRFQELESETLKSEEFQKR-LHPYKDFIATLGKLSGLHGQDLFGIWSKV
|.||. .||.||||| |....|| .||.|..||. | | |. .||.|.|| .| |.|.||... | ........| . || |.. ... .
lqSaqaflaGlfppeilgsqllnplnvyqpvpietvdsdndtl...pydscpafdellkellasdeflelflerilkllqellpglgltpsdvldlydlc
-YDPLYCESVHNFTLP--SWATEDTMTKLRELSELSLLSLYGIHKqkEKSRLQGGVLVNEILNHMKRATQIPS----------------YKKLIMYSAHD
|| |.... |...|| |. ||. . .|..|. | |||.. | ..|.||.|.||||.....| . .| ||..|.|||
kydtlllgyahglplpfcslfteeelevleyladlefyylygygd..eiaklaggpllneilarledaingdstnlnltldsnpatfpldlklylyfaHd
TTVSGLQMALDVYNGLLP---------------------PYASCHLTELYFEKG--EYFVEMYYRNetqhepYPLMLPGCSP----SCPLERFAELVGPV
||. | .||..... || ||||. .||| .. ||.|...| . ..| ||||. .|||. | ||| ..
ttiapllsaLglfddqlplpadntpfpeldrlfrtseivPyasnlvfElyecpdgneyyVrvlyng......kvlplpgcgsgpgglCplddFkelvkkf
IPQDWSTEC
.|.|. ||
lpgddfdeC
|
|||||||||
0047369 | Phosphoglycerate mutase-like | 33-372 | 4.9e-92 | 302.3 | In-house | 42-436 (438) | alignment | ||
Range on Protein: 33-372
Range on HMM: 42-436/438.0
KELKFVTLVFRHGDRSP-----------------IDTFPTDPIKESS---WPQGFGQLTQLGMEQHYELGEYIRKRYrKFLnesyKHEQV-YIRSTDVDR
|||.| ..||||.|.| |.|..| . .|.|.||||.||.||.||||...|||| ..| .|.| |.||.||||
celkqvqvlfRHGaRtPtksklkkleplwellenattypsgplsflndwlgpcgagqLTplGreqayelGkrlrkrY.glL....npedvlyvrssdvdR
TLMSAMTNLAALFPPEGVSIWNPILlWQPIPVHTVPLSEDQLLYL-PFRNCPRFQELESETLKSEEFQKR-LHPYKDFIATLGKLSGLHGQDLFGIWSKV
||.||. .|| |||||| ....||| |||||.||.| | | || | |. .||.|.|| .|.| |.||... | ........| . ..|. |.. .. .
tlqSAqaflaGlfppegtgelapil.wqpipihtipesddfllnllpsdscpafdellkeflasdeflelllkdilkrlkkllpglnltpsdvldlydlc
-YDPLYCESVHNFT--LPSWATEDTMTKLRELSELSLLSLYGIHKqkEKSRLQGGVLVNEILNHMKRATQIPS----------------YKKLIMYSAHD
|| |...... .. ..|. |.. ...|. |. | |||... | ..|.||.|.||||.....| . .| ||..|.|||
aydtlangyaglplspfcslftpeelevleyladlefyylygygn..elaklaggpllneilarledaingkstnlnltldsngvtfPldlklylyfaHd
TTVSGLQMALDVYNGLLP---------------------PYASCHLTELYF--EKGEYFVEMYYrnetqhEPYPLMLPGCSP----SCPLERFAELVGPV
||. | .||.... .| ||||. .||| ..|||.|...| ...| ||||. .|||..| ||| ..
ttiaallsaLglfddtwplpglpldkialnrlfrsseivPyasnlvfElyecpsdgeyyVrvly......ngkvlplpgcgsgpgglCplddFkelvkkl
IPQDWSTEC
.|.|. ..|
lpgdfeelC
|
|||||||||
0048439 | Phosphoglycerate mutase-like | 34-365 | 2.3e-89 | 293.3 | In-house | 8-391 (391) | alignment | ||
Range on Protein: 34-365
Range on HMM: 8-391/391.0
ELKFVTLVFRHGDRSPIDTFPT--DPIKESSW---PQGFGQLTQLGMEQHYELGEYIRKRY--RKFLNESY--KHEQVYIRSTDVDRTLMSAMTNLAALF
|||.| ..||||.|.|. ..| ||. .. . | |.|.||.||.||.||||...|||| ..|...| ....||.||.||||||.||. .||.||
elkqvqvlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvdlgllpskytlnpsevyvrssdvdRtlqSAqaflaGlf
PPEGVSIWNP------ILLWQPIPVHTVPLSEDQLLYLPFRNCPRF------QELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQ-----DLFGIWS
||.| ..... .|..|.|..|.|| || ||. . . .||| ..|. .. . ..... . ..... ...|.. .|. . ..
pplgltvilvivvesedpllnplpintcplledlllldalsalprfylseilerlaevlnrvlglnltaedvlslfdlcaketaalgsllklssplcdlf
KVYDPLYCESVHNFTLPSWATEDTMTK--LRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMkrATQIPSYKKLIMYSAHDTTVSGLQMALDVYNG
.|| |..| |...||.|.|...... |. |..| . .|... ..| ..|.||.|.||||... ... || ||..|.|||||. | .||...|
tlydtllyeyahglplpewltdellspellkqladlvnelyyyltgsgeiaklaggpllneilddl..vangpsdpklylyfaHdttiaallsaLglfnd
------LLPPYASCHLTELYFE--KGEYFVEMYYRNETQHEPY--------------PLMLPGCSP----SCPLERFAELVGPVIP
||||||. .||| .|||.|...|...| |. .| ||||. .|||..| ||| ..||
tlplpadlppyasnlvfElyecpsdgeyyVrvlynggtldlprdltlldldefllrlvlplpgcgsgpgglCplddFvelvkkrip
|
|||||||||
0048946 | Phosphoglycerate mutase-like | 34-378 | 1.1e-87 | 287.8 | In-house | 40-415 (447) | alignment | ||
Range on Protein: 34-378
Range on HMM: 40-415/447.0
ELKFVTLVFRHGDRSPI-----------------------------DTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNesyKHEQVYI
|||.| ..||||.|.|. ....... .| || |.||||.||.||.||||...|||| ..|. ...|.
elkqvqvlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkneplwpcglgqLTplGreqlyelGkrlrkrYlgllp...npseiyv
RSTDVDRTLMSAMTNLAALFPPEgvsiwnPILLWQPIPVHTVPLSEDQLLYLpfrNCPRFQELESETLKsEEFQKrlhPYKDFIATLGKLSGLHGQDLFG
||.||||||.||. .||.||||| | | .||||.|||| |.| ||. .||.|.|| ..|. ||... .|.... | || | .|
rssdvdRtlqSaqaflaGlfppe......pplgyqpipihtvpssndnlllp...sCpafkellkkela.eelke...llkellerlkkllgglnltlsd
IWsKVYDPLYCESV-HNFT-LPSWATEDTMTKLRELSELSLLSLYGIHKqkEKSRLQGGVLVNEILNHMKRATQIPSykKLIMYSAHDTTVSGLQMALDV
.. .|| |..| . |. . |.|. |.. ...|..|. |. .||.. | .||.||.|.||||.....|.. | ||..|.|||||. | .||..
vy.dlydlllyetaihglsplcslftpeelevleyladlefyyeygygd..elarlaggpllneilarledaisgds..klylyfaHdttiaallsaLgl
YNGLLP------------------PYASCHLTELYFE------KGEYFVEMYYRNETQHepyplmLPGCSP----SCPLERFAELVGPVIPqDWSTECMT
.. || ||||. .||| .|||.|...| .|.. ||||. .|||..| ||. ...| || ..|
fddelplpadnlpfnrlfrsseivPyasnlvfElyecpsslpsdgeyyVrvlyngeplp......lpgCgsgpgglCplddFkellkkflp.dweklCgl
TNSH
| |
tlsv
|
|||||||||
His_Phos_2 | Histidine phosphatase superfamily (branch 2) | 34-331 | 3e-64 | 210.1 | Pfam-A | 1-346 (347) | alignment | ||
Range on Protein: 34-331
Range on HMM: 1-346/347.0
ELKFVTLVFRHGDRSPIDTFPTDPIKES--------------------------SWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRST
|||.| .|.|||||.| ..|... .| .. . |.||. |..|..||||..|.|| ..|.. .. |.|.|||.
eLkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYpgllrdhltyedvkirss
DVDRTLMSAMTNLAALFPPEG---VSIWNPILLWQPIPVHTVPL---SEDQLLYLPFRNCPRFQE--LESETLKSEEFQKRLHPYKDFIA-TLGKL-SGL
. .|.|.||. ..|.|..||| .||... | .......|.. ....|| .||.|.. .. |. ..|...| ... .| | .| .|
serRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalctge
HGQDLFGIWSKVYDPLYCES-VHNFTLPSWATE--DTMTKLRELSELSLlsLYGI-HKQKEKSRLQGGVLVNEILNHMKRATQIPS---YKKLIMYSAHD
. . . |.|. ...| ......|..... . . ..|.|..|. ||. ....| . .|. |.|..|........ ..||..|..||
dnllfkerweklfreffeeekfdiskipelydtmkydalhnrqledlee..lyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfthD
TTVSGLQMALDVYN------GLLPPYASCHLTELYF-EKGEYFVEMYY
... | .||.... .||||. .||| .. ...|....
shiytllnaLgleekiareaspelpyasqivfelyedsekkfyvrllf
|
|||||||||
His_Phos_2 | Histidine phosphatase superfamily (branch 2) | 34-331 | 3e-64 | 210.1 | In-house | 1-346 (347) | alignment | ||
Range on Protein: 34-331
Range on HMM: 1-346/347.0
ELKFVTLVFRHGDRSPIDTFPTDPIKES--------------------------SWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRST
|||.| .|.|||||.| ..|... .| .. . |.||. |..|..||||..|.|| ..|.. .. |.|.|||.
eLkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYpgllrdhltyedvkirss
DVDRTLMSAMTNLAALFPPEG---VSIWNPILLWQPIPVHTVPL---SEDQLLYLPFRNCPRFQE--LESETLKSEEFQKRLHPYKDFIA-TLGKL-SGL
. .|.|.||. ..|.|..||| .||... | .......|.. ....|| .||.|.. .. |. ..|...| ... .| | .| .|
serRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellregaescpafawppikvekrvvelvnklkkvmdenlakrlsalctge
HGQDLFGIWSKVYDPLYCES-VHNFTLPSWATE--DTMTKLRELSELSLlsLYGI-HKQKEKSRLQGGVLVNEILNHMKRATQIPS---YKKLIMYSAHD
. . . |.|. ...| ......|..... . . ..|.|..|. ||. ....| . .|. |.|..|........ ..||..|..||
dnllfkerweklfreffeeekfdiskipelydtmkydalhnrqledlee..lyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfthD
TTVSGLQMALDVYN------GLLPPYASCHLTELYF-EKGEYFVEMYY
... | .||.... .||||. .||| .. ...|....
shiytllnaLgleekiareaspelpyasqivfelyedsekkfyvrllf
|
|||||||||
subfamily_ACP6_pd | Subfamily ACP6 | 68-376 | 3e-41 | 133.3 | In-house | 76-375 (376) | alignment | ||
Range on Protein: 68-376
Range on HMM: 76-375/376.0
GQLTQLGMEQHYELGEYIRKRYR---KFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILlwqpipVHTVPLSEDqLLYLPFRNCPRF
||||. ||.| ..||. .|||| ||| .... ..||||||...||| || .| |. . .. || ..| |. || . ||
GqLtkvGmqqvfdLGrkLrkrYvedikfLsqefnpqevyiRstnieRtlesarclvaGLygkiiiqkelpii......lytdeedee.vlyPnrqrcpll
QELESETLKSEefqKRLHPYKDFIATLGKLSGLHGQDLFGiWSKVYDPLYCESVHNFTLPSwATEDTMTKLRELSELSLLSLY--GIHKQKEKSRLQGGV
.. .. || | . .. ... . .. .. . . . | . . || . | ..| . . . .|. | | . .|| .| |
srayrsvrksa...islpGisedtkqiadvldiseekkld.fvslrDniaArlaHnlkvpp.ilkdvidliekhAveelvvlleggdrpekeilklsvGk
LVNEILNHMKRATQIPSY-KKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFE-KGEYFVEMYYRNETQHepyplmLPGC-SPSCPLERFAEL
...|||.....|.. .. .|| .|||||||.. | .||.|... ||.|. ||| . .||||| ..|...... |.|. . .||| | .|
vlkeilenlekakekeiparklrLysaHDttlmtLLlalgvFDdkWPpfaadvileLyedkageyfvrvlYqekelr......lrgseedlvPlekFkal
VGPVI-PQDWSTECMTTN
. ... |.|...|| ...
lavlvlpkdyaaeCkled
|
|||||||||
subfamily_PXYLP1_pd | Subfamily PXYLP1 | 67-331 | 1.1e-21 | 68.5 | In-house | 103-366 (419) | alignment | ||
Range on Protein: 67-331
Range on HMM: 103-366/419.0
FGQLTQLGMEQHYELGEYIRKRYRKF---L--NESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGvsiwnpillWQPIPVHTVPlseDQLLYLPFRNC
||||| |. || |.|. .|| | | | .. .. ..|.. .| ||| ||. | .|.| . .. | |...| . . | |
lgqLtqkGvvqhLevGdllrkvYakklklLlkpnelssDevvlettrkrrtlqsalallygllpkak.........lkairvresp...svafClgeCsC
PRFQELESETLKSEEFQKRLhPYKDFIATLG-KLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWaTEDTMTKLRELSELSLLS----LYGIHKQKEKS
| ... | . .. .|. . | ..| | | | |.. | | . || .|| | ... . .|. . ..|
PallrkrlekeadkqlLlrg.kvldvmksvgetlkgtilqttlngisnpvdalltvlChnvslPcr.reGcvepshvdvlhkladelsqrsakksyykls
-RLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFE--KGEYFVEMYY
.|. |...|...|..... . .| ..||.|| |.. | ||.. .. .. ||| . ||| . ||.. . |
GllraypllrdivsrmlkiieGvdkekfvlysghDvtlrplvaaLglseartiayasrlvfelyrreaskeyylrvly
|
|||||||||
subfamily_HP2-Group1_pd | Subfamily HP2-Group1 | 208-375 | 8.2e-20 | 62.5 | In-house | 250-419 (422) | alignment | ||
Range on Protein: 208-375
Range on HMM: 250-419/422.0
KVYDPLYCESVHNFTLPSWATEDTMTklRELSEL--SLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNG
.. | |. ||...| ||| . | | || | . .....| | |. .| ...... . ...|...|| ||||. | ||.| ..
dlvdclithqchnaaipdkltedlak..rgldellyrsysslkypsvekyarvGiGfllkdiwkevnesltGedlrkfllysGhdttliqllsalnvdef
LLPPYASCHLTELYFEKG-------EYFVEMYYRNETQHEPYplmlPGCSPsCPLERFAELVGPVIPQDWSTECMTT
||||| | ||. . .| | . | . .. |. . . |..|.| . . |||.| .| .
kwppyasllllellevstapaastpqyavrvlynGklkklpf....cdane.csyeqfeaylstviphddaedckvs
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subfamily_HP2-Group1_pd | Subfamily HP2-Group1 | 67-182 | 6e-12 | 36.6 | In-house | 92-204 (422) | alignment | ||
Range on Protein: 67-182
Range on HMM: 92-204/422.0
FGQLTQLGMEQHYELGEYIRKRYRK--FLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNpillWQPIPVHTVPLSEDQLLyLPFRNCPRF
.||| | |. |. .|| | . ||. |.. .||.|| |. ||..|| . . ..|..... . | ....| |.. ||.
vaqltleGykqqelnGqilrkvyvdtGflkssldssevylrsddesrtilsaqalilGmypqdtkaedr....aqvvdlytrdklfdsie.anadlcpkl
QELESETLKSEEFQKRLH
| . . |||. ... |.
seyntqflksdtwlnhlk
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subfamily_MINPP1_pd | Subfamily MINPP1 | 68-169 | 4.7e-10 | 30.9 | In-house | 90-187 (420) | alignment | ||
Range on Protein: 68-169
Range on HMM: 90-187/420.0
GQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNpillWQPIPVHTVPLSEDQLLyLPFRNCPRFQEL
..|.. | |...||.. . .|. ....| |........||. ||. || . .|.. . | . ... . . ..|.|| .| .|.....
kslvaqgqeeleelakrlarrfpalfeevynpdsfsfastakkRtvksaqaFaeGLsetgevlgde....fnivlqeiseqesdklL.rffdsCkkyknk
E-S
vkk
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