Gene PPIP5K1 in Homo sapiens

Synonym: HISPPD2A, IP6K, IPS1, VIP1, hsVIP1, PPIP5K1

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily PPIP5K
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP164_AA protein Get Run
HsapP164_AA_339-924 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PPIP5K_pd Subfamily PPIP5K 366-913 9.4e-284 931.6 In-house 4-550 (551) alignment 
Range on Protein: 366-913
Range on HMM: 4-550/551.0
QIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEE
.|......|.||.||||||||..||||||||.|||||||||||.||||.||.|..||||..|||....|||.|.||||||||.| ||.|.||.   ||||
eikkklalekedlPivpttsgkkmelrcviaviRHgDRtPkqklkmevthpkflelfekydgykkkevklkkpkqLqevLdivralleekekkseeeiee

KTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGV-KASNEGQDPQREtlAPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRL
.. ||.|||.|||.|||||||||||||.|..... |.|.| ....||  ..||||.|||||||||||.||||||||||||.||||.|||||.||.|||||
eksklkqlknvLekyghfsGinrkvqlkylkkrtektsseeeeskre..eeslllilkWGGEltpagkvqAeelGrafRclyPggdgdyaglpGlgllrL

HSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDGDSlSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTSLLNS
|||.||||||||||||||||||||||||||||||||||||||.|||||.|.|||.| |. ...|.|||..||..||.|  |.|||...|||..|.|||..
hstyrhdlkiyasdEgRvqmtAaafakgllaleGeltpilvqlvksanvndlLDddkda.kklqdrvkkklhellqedkeftpedieklaPeksksllka

MTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLS
...|.|||||...|..|.|.|......|.....|.||.|||||||||. .||.|||..|..|....||||||||||..|||.|||.||||. |.||..|.
lkkiknPvkvikkvvelveelvkilkdriekkkskdlrlyhsetleLlkrRWeklekeFkekekkfdiskipdiyDsikYdlqHnkslgleqtselykla

KALADVVIPQEYGISREEKLEIAVGFCLPLLRKILLDLQRTH-EDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETQDAQWQ
|||||.||||||||..||||||. ..||||||||. ||.||. |||..|.|.| .|.||||| ||||||||||||||.||||.|.||||||||..|.||.
kaladiviPqEYGitkeekleigkaiclpLlrkirnDlkrtekedetknrlepalskgvlsPerhvrtrlYFtsEsHihsllnvlrygglldevkdeqwk

RALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFHVELHFSPGVKGVE
||||||||..||||.||||.|||||...|. |||||.|||.||||||..|
raldylsaleElnYltqivlmlyEdkskdasseerfsvelkfspGvktqe
His_Phos_2 Histidine phosphatase superfamily (branch 2) 390-906 1.1e-110 362.8 Pfam-A 1-347 (347) alignment 
Range on Protein: 390-906
Range on HMM: 1-347/347.0
ELRCVIAIIRHGDRTPKQKMKMEVKHPRFFALFEkhggyktgklklkrpeqlqevlditrlllaelekepggeieektgkleqLKSVLEMYGHFSGINRK
||..|...|||||||||||.|..|....|..|..                                                 || |||..|||.|..||
eLkgvvvviRHGdRtPkqkfkksvtsekfisllk.................................................lknvlekkghfpgtkrk

vqltyyphgvkasnegqdpqretlaPSLLLVLKWGGeLTPAGRVQAEELGRAFRCMYPggqgdyagfpgcGLLRLHSTFrHDLKIYASDEGRVQMTAAAF
                         ..|.|.||||| ||..|| ||||||. .|..||            ||||.|.|  .|.||..|.|.||...|.||
.........................eklqlilkwgg.lThsGrkqaeelGeqlrqrYp............gllrdhlty.edvkirssserRvlaSAqaf

AKGLLALEGELtpilvqmvksanmnglLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTsllnsmtIIQNPVKVCDQVFALIENLTHQI
|.|||..||||                | |. ..|...... | ..... ...... .|.... . ....       .|... .|...|  | .......
aaGllgpegel................llsirkdllddsnaakdtmdevkkklkellregaescpafawp.......pikvekrvvelvnklkkvmdenl

RERMQDPrsvdlqlYHSETLELMLQRWSKLERDFRQKSgRYDISKIPDIYDCVKYDVQHNGSlgLQGTAELLRLskaladvvipqeYGISREEKLEIAVG
..|....       ...|. .|. .||.||.|.|...  ..||||||..||..|||..||    |.   || .|            |||..||||.|...
akrlsal.......ctgednllfkerweklfreffeee.kfdiskipelydtmkydalhnrq..ledleelykl............ygigdeeklkigll

FCLPLLRKILLDLQRTHedesvnklhplysrgvlsPGRHVRTRLYFTSESHVHSLLSVFrygGLLDETQDAqwqraldylsAISELNYMTQIVIMLYEDn
...|||.||| ||..|.                  | ||...|||||..||...||...   || ......          |..||.|..|||..|||| 
llnpllkkilsdleetq..................psrhaklrlyfthDshiytllnaL...gleekiare..........aspelpyasqivfelyed.

tqdplSEERFHVELHFS
     ||..|.|.|.||
.....sekkfyvrllfs
His_Phos_2 Histidine phosphatase superfamily (branch 2) 390-906 1.1e-110 362.8 In-house 1-347 (347) alignment 
Range on Protein: 390-906
Range on HMM: 1-347/347.0
ELRCVIAIIRHGDRTPKQKMKMEVKHPRFFALFEkhggyktgklklkrpeqlqevlditrlllaelekepggeieektgkleqLKSVLEMYGHFSGINRK
||..|...|||||||||||.|..|....|..|..                                                 || |||..|||.|..||
eLkgvvvviRHGdRtPkqkfkksvtsekfisllk.................................................lknvlekkghfpgtkrk

vqltyyphgvkasnegqdpqretlaPSLLLVLKWGGeLTPAGRVQAEELGRAFRCMYPggqgdyagfpgcGLLRLHSTFrHDLKIYASDEGRVQMTAAAF
                         ..|.|.||||| ||..|| ||||||. .|..||            ||||.|.|  .|.||..|.|.||...|.||
.........................eklqlilkwgg.lThsGrkqaeelGeqlrqrYp............gllrdhlty.edvkirssserRvlaSAqaf

AKGLLALEGELtpilvqmvksanmnglLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTsllnsmtIIQNPVKVCDQVFALIENLTHQI
|.|||..||||                | |. ..|...... | ..... ...... .|.... . ....       .|... .|...|  | .......
aaGllgpegel................llsirkdllddsnaakdtmdevkkklkellregaescpafawp.......pikvekrvvelvnklkkvmdenl

RERMQDPrsvdlqlYHSETLELMLQRWSKLERDFRQKSgRYDISKIPDIYDCVKYDVQHNGSlgLQGTAELLRLskaladvvipqeYGISREEKLEIAVG
..|....       ...|. .|. .||.||.|.|...  ..||||||..||..|||..||    |.   || .|            |||..||||.|...
akrlsal.......ctgednllfkerweklfreffeee.kfdiskipelydtmkydalhnrq..ledleelykl............ygigdeeklkigll

FCLPLLRKILLDLQRTHedesvnklhplysrgvlsPGRHVRTRLYFTSESHVHSLLSVFrygGLLDETQDAqwqraldylsAISELNYMTQIVIMLYEDn
...|||.||| ||..|.                  | ||...|||||..||...||...   || ......          |..||.|..|||..|||| 
llnpllkkilsdleetq..................psrhaklrlyfthDshiytllnaL...gleekiare..........aspelpyasqivfelyed.

tqdplSEERFHVELHFS
     ||..|.|.|.||
.....sekkfyvrllfs
0049059 Phosphoglycerate mutase-like 340-907 8.4e-62 202.5 In-house 2-397 (435) alignment 
Range on Protein: 340-907
Range on HMM: 2-397/435.0
KNSMKYYDDCAKILgnTIMRELAPQFQIPWSIPTEAeDIPivpttsgTMMELRCVIAIIRHGDRTPKQKM--KMEVKHPRFFALFEKHGgyktgklklkr
|  ...|.|...||  ...  |.| |..|.. . .  |.|       . .||..|....|||.|||..|.  |.|. ..... |. ...           
ktlapvysdgfnil..lllgtlspyfsapgvfgisl.dvp.......egcelkqvqvlfRHGaRtPtsklikklealwekllslltypn...........

peqlqevlditrlllaelekepggeieektgkleqlksvlemyghfsginrkvqltyyphgvkasnegqdpQRETLAPSLLLVLKWgGELTPAGRVQAEE
                                                                          .  ..  ..|.. ||||| ||.|| |
.......................................................................gplsflndwnyplga.geLTplGreqaye

LGRAFRCMYpggqgdyAGFpgcgllrlhstFRHD-LKIYASDEGRVQMTAAAFAKGLLALEgeltpilvqmvksanmnglldsdgdslsscqhrvkarlh
||. .| .|        ..           ...| .....||..|....|.||..||.  |                                       
lGkrlrkrY.......gfL...........ynpdevyvrssdvdRtlqSaqaflaGlfppe.......................................

hilqqdapfgpedydqlapTRSTSLLNSMTIIQNPVKVCdqVFALIENLTHQIRERMQDPRSVDLQlyHSETLELMLQRWSKLERDFRQKSGrYDISKIP
                   . ...|||.....| ..     | ...  |..... ....  . .|.   .|.|||.|.|..|| ... .. | ...|...
...................ilgsqllnplnvyqpvpiet..vdsdndtlpydscpafdellkella..sdeflelflerilkllqellpglg.ltpsdvl

DIYDCVKYDVQHNGS-----LGLQG--TAELLRLSKALADVVIPQEYGISReeklEIAVGFCLPLLRKILLDLQRTHEDESVNkLHPLYSRGVLSPGRHV
|.||..|||....|.     | . .  | |.|.  ..|||......||...    |||   . |||..|| .|.......|.| |...............
dlydlckydtlllgyahglplpfcslfteeelevleyladlefyylygygd....eiaklaggpllneilarledaingdstn.lnltldsnpatfpldl

RTRLYFTSESHVHSLLSVFRY-GGLLDETQDAQWQRALDYLSAISELN-YMTQIVIMLYEDNTqdplsEERFHVELHFSP
. .|||........|||.. . .. |. . | .....||.|  .||.. |....|. |||...     .....|..... 
klylyfaHdttiapllsaLglfddqlplpadntpfpeldrlfrtseivPyasnlvfElyecpd.....gneyyVrvlyng
0047369 Phosphoglycerate mutase-like 351-910 3.8e-60 197.3 In-house 3-402 (438) alignment 
Range on Protein: 351-910
Range on HMM: 3-402/438.0
KILGNTIMRELAPQFQIPWSIP-TEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPkQKMKMEvKHPRFFALFEKHGGYKTgklklkrpeqlqevlditr
|||.............. . .| ..| ........  . .||..|....|||.||| .|.|.. |.. .. |.|....|..                   
kilapvlsvdfnillhlgtlspyfsapgvglisldvpegcelkqvqvlfRHGaRtP.tksklk.kleplwellenattyps...................

lllaelekepggeieektgkleqlksvlemyghfsginrkvqltyyphgvkasnegqdPQRETLaPSLLLVLKWgGELTPAGRVQAEELGRAFRCMYpgg
                                                          .. . | ...| .... |.||| ||.|| |||. .| .|   
..........................................................gplsfl.ndwlgpcga.gqLTplGreqayelGkrlrkrY...

qgdyagfpgcGLLrlhstFRHDL-KIYASDEGRVQMTAAAFAKGLL--ALEGELTPILVQmvksanmnglldsdgdslsscqhrvkarlhhilqqdapfg
          |||     ...|. ....||..|....|.||..||.   ..|||.|||.|                                        
..........glL.....npedvlyvrssdvdRtlqSAqaflaGlfppegtgelapilwq........................................

pedydqlaptrstsllnsmtiiQNPVKVCDQVFALIENL-THQIRERMQDPRSVDLQLyhSETLELMLQRWSKLERDFRQKSGrYDISKIPDIYDCVKYD
                      . |. .       . ||  ..   .... .. .|..  .|.|||.|....|. ... . .. ...|...|.||...||
......................pipihtipesddfllnllpsdscpafdellkeflas..deflelllkdilkrlkkllpgln.ltpsdvldlydlcayd

VQHNGSLGLQG-------TAELLRLSKALADVVIPQEYGISReeklEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPgRHVRTRLYFTSE
 ..||. ||.        | |.|.  ..|||.. ...||...    |.|   . |||..|| .|... ...|.|  ..|.|.||..| .... .|||...
tlangyaglplspfcslftpeelevleyladlefyylygygn....elaklaggpllneilarledaingkstnlnltldsngvtfP.ldlklylyfaHd

SHVHSLLSVFRY-GGLLDETQDAQWQRALDYLSAISELN-YMTQIVIMLYEDNtqdplSEERFHVELHFSPGVK
.....|||.. . .  .. ... ... ||..|  .||.. |....|. |||..     |.....|...... | 
ttiaallsaLglfddtwplpglpldkialnrlfrsseivPyasnlvfElyecp.....sdgeyyVrvlyngkvl
0048946 Phosphoglycerate mutase-like 352-911 4.9e-57 186.8 In-house 2-377 (447) alignment 
Range on Protein: 352-911
Range on HMM: 2-377/447.0
ILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVkhPRFFALFEKHggyktgklklkrpeqlqevlditrll
.||....... ... . ...| .. . . .|..  . .||..|....|||.|||..|.....  . .. |....                          
llgpaladgfnillhlgtlspyfsvpgygipepvpegcelkqvqvlfRHGaRtPtkkylkgl..eplldllkna..........................

laelekepggeieektgkleqlkSVLEMYGHFSGINR-KVQLTYYPHGVkasnegqdpqretlapslllvLKWgGELTPAGRVQAEELGRAFRCMYpggq
                       .|||..|..|..|. |.||.. |..                      ... |.||| || |. |||...| .|    
.......................nvlelggdlsflndwkyqlkneplwp.....................cgl.gqLTplGreqlyelGkrlrkrY....

gdyagfpgCGLLRlhstFRHDLKIYASDEGRVQMTAAAFAKGLLALEG--ELTPILVQMVKSANMNGLLDsdgdslsSCQHRVkarlhhilqqdapfgpe
         |||.     ........||..|....|.||..||.  |.  . .|| ...|.| | | ||.       ||. ..                 
........lgllp....npseiyvrssdvdRtlqSaqaflaGlfppepplgyqpipihtvpssndnlllp.......sCpafk.................

dydqlaptrstsllnsmtiiqnpvkvcdqvfalienlthqirermqdprSVDLQLYHsETLELMLQRWSKLERDFRQkSGRYDISKIPDIYDCVKYDVQH
                                                 ..  . .. | |. .|... ..  .. .    ...|.. |.||...|. ..
.................................................ellkkela.eelkellkellerlkkllg.glnltlsdvydlydlllyetai

NGSLGLQG--TAELLRLSKALADVVIPQEYGISREekleIAVGFCLPLLRKILLDLQRTHEDESvnklhplysrgvlspgrhvRTRLYFTSESHVHSLLS
.|.  | .  | |.|.  ..|||.. ..|||...|    .|   . |||..|| .|.......|                   . .|||........|||
hglsplcslftpeelevleyladlefyyeygygde....larlaggpllneilarledaisgds...................klylyfaHdttiaalls

VFrygGLLDEtqdaQWQRALDYLSA-----ISELN-YMTQIVIMLYEDNTQDPLSEERFhVELHFSPGVKG
..   || |     ....  |.|..     .||.. |....|. |||.....| ..|.. |...... .  
aL...glfdd....elplpadnlpfnrlfrsseivPyasnlvfElyecpsslpsdgeyy.Vrvlyngeplp
0046349 Phosphoglycerate mutase-like 389-924 8.8e-53 172.9 In-house 5-367 (409) alignment 
Range on Protein: 389-924
Range on HMM: 5-367/409.0
MELRCVIAIIRHGDRTPKQKmkmevkhprffalfekhggyktgklklkrpeqlqevlditrlllaelekepggeieektgkleqlksvLEMYGHFSGINR
.||..|....|||.|||..|                                                                    |.......|||.
ceLkqvqvlfRHGaRtPtkk....................................................................lsflpnwpginw

KvqltyyphgvkasnegqdpqretlapslllVLKWG-GELTPAGRVQAEELGRAFRCMY--PGgqgdyagfpgcgLLRLHSTFRHD-LKIYASDEGRVQM
.                              . ..| |.||| ||.|| |||...| .|  .|            ||. .|....| .....||..|...
t..............................ngpcgagqLTplGreqayelGkrlrkrYvdlg............LlpsnslynpdeiyvrssdvdRtlq

TAAAFAKGLL-ALEGELTPILVQMVKSANMNGLLDSDGDslsscqhrvkarlhhilqqdapfgpedydqlaptrsTSLLNSMTIIQNPVKV-CDQVFALI
.|.||..||. .|.||..|.|.|..........  .. .                                    .|  ...  . .|..  |..  .|.
SAqaflaGlfpplggeivpllrqdlldppfqpipidtvp....................................iseddalddtllppdslcpaldkll

ENLTHQIRERMQDPrsVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPD----IYDCVKYDVQHNGSLGLQGTAELLRLSKALADvVIPQEYGI
..   ...| .. .  ||..|.. |.|. . . ..|| . . ..   ...... |    .||. .|.  |. .|  ..     .. |.||. . ..||..
kenlkslsevlefl..vdealldlelldetkdllkklaerlnselpglnltdpldvasllydtllyetahglplppwcdlftpeelkvlay.ladleyyy

SREEKlEIAVGFCLPLLRKILLDLQRTHEDesvnklhplysRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYgglldetqdaqWQRALDYlsaISELNYM
 . .. |.|   . |||..|| .|... ..           ... .. .... .|||........|||.. .           ..|. ..       .|.
lygsg.elaklaggpllneilarledaisg...........knpvtfpldlklylyfaHdttiaallsaLgl...........fdrlfrs...sdippya

TQIVIMLYEDntqdpLSEERFHVELHFSPGVKGVEEEGSApagCGF
...|. |||.      |.....|......|.  . . |.    | .
snlvfElyec.....psdgeyyVrvlynggplplpgcgeg...cpl
0048439 Phosphoglycerate mutase-like 386-908 1.1e-51 169.4 In-house 6-342 (391) alignment 
Range on Protein: 386-908
Range on HMM: 6-342/391.0
GtmMELRCVIAIIRHGDRTPKQKMKM--EVKHPRffalfekhggyktgklklkrpeqlqevlditrlllaelekepggeieektgkleqlksvlemyghf
|  .||..|....|||.|||......  .  ...                                                                  
g..celkqvqvlfRHGaRtPtssypnkldpllnk..................................................................

sginrkvqltyyphgvkasnegqdpqretlapsLLLVLKWG-GELTPAGRVQAEELGRAFRCMYpggqgdyagfPGCGLLRLHSTF-RHDLKIYASDEGR
                                 ||.. ..| ||||| || |. ||||..| .|          .  |||. ..|. ........||..|
.................................llpngpcglgeLTplGreqlyelGrrlrkrY..........vdlgllpskytlnpsevyvrssdvdR

VQMTAAAFAKGLLAlEGELTPILVQMVKSANmNGLLDSDGDSLSSCQhrVKARLHHILQQDAPFGPEDYDQLAPTRS--TSLLNSMtiiqnpvkvcdqvf
....|.||..||.  ...||.|||..|.|.. ..| . . .. . ..  ....|  . . .. . .| ...||.  .   .|....              
tlqSAqaflaGlfp.plgltvilvivvesed.pllnplpintcplle..dlllldalsalprfylseilerlaevlnrvlglnlta..............

alienlthqirermqdprsvdlqlyhsETLELMLQRWSKLERDFRQKSGR-YDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRL--SKALADVVIPQEY
                           |..........|.  .. ..... ...... ..||...|.  |. .|   .| ||| .   |.|||.|....|
...........................edvlslfdlcaketaalgsllklssplcdlftlydtllyeyahglplpewltdellspellkqladlvnelyy

GISREEklEIAVGFCLPLLRKILLDLqR-THEdesvnklhplysrgvlspgRHVRTRLYFTSESHVHSLLSVFrygGLLDETQDAQWQRaldylsaiseL
.. . .  |||   . |||..|| || . ...                   .... .|||........|||..   || . |.. ....          .
yltgsg..eiaklaggpllneilddl.vangp...................sdpklylyfaHdttiaallsaL...glfndtlplpadl..........p

NYMTQIVIMLYEDNTQdplseERFHVELHFSPG
.|....|. |||....     ....|..... |
pyasnlvfElyecpsd.....geyyVrvlyngg
0053031 Phosphoglycerate mutase-like 390-908 7.4e-50 163.2 In-house 2-302 (342) alignment 
Range on Protein: 390-908
Range on HMM: 2-302/342.0
ELRCVIAIIRHGDRTPKQKMKMEVKHPRFFalfekhggyktgklklkrpeqlqevlditrlllaelekepggeieektgkleqlksvlemyghfsginrk
||..||...|||.|||..|.......  |.                                                                      
eLkqvivlvRHGaRtPlskgpldplnewfy......................................................................

vqltyyphgvkasnegqdpqretlapslllvlKWG-GELTPAGRVQAEELGRAFRCMYpggqgdyagfpgCGLLrlHSTFRHD-LKIYASDEGRVQMTAA
                                ..| ||||| || || ||||..| .|            .|||  .||...| .....||..|....|.
................................pcgageLTplGreqayelGrrlrkrY............lgll..pstynpdevyvrssdvdRtlqSAq

AFAKGLLalEGELTPILVQMVKsanmnglldsdgdslsscqhrvkarlhhilqqdapfgpedydqlaptrstsllnsmtIIQNPVKVCDQVFALIENLTH
||..||.  ..| ||||.....                                                         ... |. ... ..  . .. .
aflaGlf..ppegtpilnpllg.........................................................wqpipihtepessdalllpny

QIRERMQDPRSVDLQL-YHSETLELMLQRWSKLERDFRQK-SGRYDIskIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKle
. . .... .. .|.. ...|.|| .|....|| ... .. |...|.  . |.||...|...|. .|    | ..|   |||..... ..||..  ..  
dpcpafdkllkealaseevkellerylellqklskglgltlsdlldl..vsdlydlllyelahglplppwctlftleelkalyaldllyyyglgpgne..

IAVGFCLPLLRKILLDLQRTHEDesvnklhplysrgvlspGRHVRTRLYFTSESHVHSLLSVFRYGglldetqDAQWQraldylsaiselNYMTQIVIML
.|   . |||..|| .|......                 ..... .|||........|||.. .        | |.             .|....|. |
laklaggpllneilarleekisg.................pldlklylyfahdttiaallsaLglf.......ddqlP............pyasnlvfEl

YEDNtqdplseERFHVELHFSPG
|||.       ....|......|
yedp.......geyyVrvlyngg
0049226 Phosphoglycerate mutase-like 390-911 1e-49 162.6 In-house 2-305 (342) alignment 
Range on Protein: 390-911
Range on HMM: 2-305/342.0
ELRCVIAIIRHGDRTPKQKMKMEVKHPRFfalfekhggyktgklklkrpeqlqevlditrlllaelekepggeieektgkleqlksvlemyghfsginrk
.|..|...||||||||..|........ |                                                                       
kLkqvqvliRHGdRtPlakgpldflnewf.......................................................................

vqltyyphgvkasnegqdpqretlapslllvlkWG---GELTPAGRVQAEELGRAFRCMYpggqgdyagfpgCGLLrlHSTFRHD-LKIYASDEGRVQMT
                                 ||   ||||| ||.|| ||||..| .|            .|||  .||...| .....||..|....
.................................wgcglgeLTplGreqayelGrrlrkrY............lgll..pstynpdevyvrssdvdRtlqS

AAAFAKGLLalEGELTPILVQMVKsanmnglldsdgdslsscqhrvkarlhhilqqdapfgpedyDQLAPTRSTSLLNSMTIIQnPVKVCDQVFALIENL
|.||..||.  ..|||||||....                                          |. |. ...  |....   | . |. .  |...|
aqaflaGlf..ppeltpilvplld.........................................wqpipiitepesndtllll.pydscpnfdkllkel

ThqirermqdpRSVDLQLYHSETLELMLQRWSKLERDFRqksgryDISKIPD-IYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEkl
            | ..||...|.|.|. . ...|. ..       ..|...| .||...|...|. .|    . ..|.  |||........|||.. |  
l..........kseevqlfleeildllkklskllglnls......tlsdvadtlydlllyelahglplppwcslftleelkalyaldllyyygigyge..

EIAVGFCLPLLRKILLDLQRTHEdesvnklhplysrgvlsPGRHVRTRLYFTSESHVHSLLSVFRYGGlldetqdAQWQraldylsaiselNYMTQIVIM
|||   . |||..|| .|....|                 ...... .|||........|||.. . .        |.             .|....|. 
eiarlaggpllneilarleeaie.................gpsdlklylyfahdttiaallsalglfd.......dqlP............pyasnlvfE

LYEDNtqdplseERFHVELHFSPGVKG
|||..       ....|......|| .
lyecd.......geyyVrvlynggvls
subfamily_ACP2_pd Subfamily ACP2 389-596 3.9e-08 25.2 In-house 7-103 (361) alignment 
Range on Protein: 389-596
Range on HMM: 7-103/361.0
MELRCVIAIIRHGDRTPKQKMKMEVkhprffalfekhggyktgklklkrpeqlqevlditrlllaelekepggeieektgkleqlksvlemyghfsginr
..|. | ...|||||.|..... .                                                                            
rkLkfvqvlfRHGdRsPlntypndk...........................................................................

kvqltyyphgvkasnegqdpqretlaP------SlllvlKWgGELTPAGRVQAEELGRAFRCMYPGGQGdyagfpgcgLLRLHsTFRHDLKIYASDEGRV
                                 .      . |.||. |  |. |||. .|  |   ..         .|      .  .... ||  | 
..........................ykedewpq.....gl.GqLTeeGmqqqyeLGkfLrkrYvedtk.........fldak.ynpkqiyvrSsdvnRT

QMTAAAFAKGLLAL
 |.| ... ||.  
lmSaqsvlaglfpp
0051064 Phosphoglycerate mutase-like 526-641 3.5e-06 19.7 In-house 29-171 (241) alignment 
Range on Protein: 526-641
Range on HMM: 29-171/241.0
ELTPAGRVQAEELGRAFRCM--YPGgqgdyagfpgcgllrlhstfrhdlKIYASDEGRVQMTAAAFAKGLLA--LEGELTPILVQMVKSANM--------
.||. || ||..||.... .   .                         ..|.|.  | . ||...|..|    |. ...| |  .   |          
pLtelGreqaralgerladlgikfd........................avysSpllRaiqTaeiiaealglpllpvvvdprlrEidfgalegltleeia

--------NGLLD-------------------------------SDGDSLSSCQHRVKARLHHILQQ
          | |                                .| ||  ...||.. |...|..
ekfpeelvawlrdpldvrppllelldlllllldlryagllddllpggEsladvaaRvlpaleellar
RimK RimK-like ATP-grasp domain 246-344 8.8e-06 14.6 Pfam-A 79-176 (190) alignment 
Range on Protein: 246-344
Range on HMM: 79-176/190.0
IYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPAldGKVERDSEGKEIRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMK
.  ||. . . .|..|. || .   |  |.|    |      .      .. |.  |. .| |.  |....|.| |.|...   .|..||    .|.. |
lvQefIeeaenrdiRvlVvgdevvaalervske..GdfrsNlarGgvaeklqlseeeeelaikaaeameldvlgvDileskrgllvlEvNssvglkkiek