Gene TIM50 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily TIM50
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP078_AA protein Get Run
MbreP078_AA_131-257 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TIM50_pd Subfamily TIM50 133-258 6.7e-55 176.6 In-house 1-124 (126) alignment 
Range on Protein: 133-258
Range on HMM: 1-124/126.0
TIVLDLEDTLLHSEWTFEHGWRTKKRPFLANFLESCVmELgLELVVFSESQVAEAMLLIDKMDPKQCIQYRLYKPHMRYVDGEPVKDLDWLNRDLSKVIV
|.||.|.|.|.|.|||...|||.||||....|||... || .|.|||...|...|. ||||.||||.|.|||.. ...|||||.||||..||||||||||
tlvlelkdvlvhpewtyktGwrfkkrPgvdafleqla.el.feivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskviv

IDDKPEQVRKHKDNVLRVRPFKGTPE
.| ....|.....|.|......|. .
vdldkksvklqpenalalkkweGnad
NIF NLI interacting factor-like phosphatase 132-284 1.9e-36 117.3 Pfam-A 1-159 (159) alignment 
Range on Protein: 132-284
Range on HMM: 1-159/159.0
YTIVLDLEDTLLHSEWT-----------FEHGWRTKKRPFLANFLESCvMELgLELVVFSESQVAEAMLLIDKMDP-KQCIQYRLYKPHMRYVDGEPVKD
.|.||||..||.||...           ... ...||||.|..||...  .   |.|.|. |.   |  ..||.|| |. ...|||. .... .|. |||
ktLVLDLDetLvhskekkdlkedgkkveektkasvkkRPgldeFLkel.ska.yevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyvKd

LDWLNRDLSKVIVIDDKPEQVRKHKDNVLRVRPFKGTPeqANDRELLDVLTFLaNIVQsRVPDVR
|..|.||||.|...||.|.......||.. ..||.|.    .|.|||..|.||   .. .. |||
LsllgrdlsrvvivDdsprsfelqpdngipiepfygds..dkdtellkllpfl.eale.ksddvr
CPDc_SM00577 132-257 2.4e-27 87.7 In-house 3-143 (146) alignment 
Range on Protein: 132-257
Range on HMM: 3-143/146.0
YTIVLDLEDTLLHS----------EWTFE-----HGWRTKKRPFLANFLESCVMElgLELVVFSESQVAEAMLLIDKMDPKQCIQYR-LYKPHMRYVDGE
...||||..||.||          |.. .     . ....|||.. .||...      |||.|. ..   |  ..| .|||. ..|| ||. ..|.|.|.
kvLVlDLdetLvhsanmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaakl..felvifTsaskkyadtildllDpkrllkyrvlyRqdcrlvkgk

PVKD-LDWLNRDLSKVIVIDDKPEQVRKHKDNVLRVRPFKGTP
 .|| |. |..|||||..||...|... ...| | ..|..  .
llkddlsllkvdlskvviiDnseestlvnpenalkikpyisal
subfamily_CTDSPL2_pd Subfamily CTDSPL2 155-244 2e-18 58.7 In-house 38-126 (142) alignment 
Range on Protein: 155-244
Range on HMM: 38-126/142.0
TKKRPFLANFLEScvMELGLELVVFSESQVAEAMLLIDKMDPKQC-IQYRLYKPHMRYVDGEPVKDLDWLNRDLSKVIVIDDKPEQVRKHK
 ..|||| .|||   .   .|...|. |.   |  |.| .||..  |..||.. |  .|||. .|||. | |||.|.|..|..|.      
vrlrpflrefler..vsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyikdlsilGrdlektiivdnspqafayql
subfamily_SCP_pd Subfamily SCP 153-251 1.5e-15 49.2 In-house 37-133 (142) alignment 
Range on Protein: 153-251
Range on HMM: 37-133/142.0
WRTKKRPFLANFLEScvMELGLELVVFSESQVAEAMLLIDKMDPKQCIQYRLYKPHMRYVDGEPVKDLDWLNRDLSKVIVIDDKPEQVRKHKDNVLRVR
    |||.. .||.   .    |.|.|. |    |  . | .| |. ...||.. .  .  |  ||||  | |||.|||..|. |.    |..| . |.
vyvlkrphvdeflkr..vgelfevvlftaslakyadpvadlldkkkvlrarlfrescvfhkgnyvkdlsrlgrdlkkviivdnspasyifhpenavpve
subfamily_DULLARD_pd Subfamily DULLARD 155-258 2.2e-15 48.7 In-house 48-150 (153) alignment 
Range on Protein: 155-258
Range on HMM: 48-150/153.0
TKKRPFLANFLEScVMElGLELVVFSESQVAEAMLLIDKMDPKQ-CIQYRLYKPHMRYVDGEPVKDLDWLNRDLSKVIVIDDKPEQVRKHKDNVLRVRPF
  |||..  ||.  | .   .||.|  |    |. ..||.| ..  .. |.|. | .  .|. .|||  .. |||.||..|. |.. ||. || . .. .
vykrPhvDlfLdv.vsk.WydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvlesgkytkdlslvssdlssviilDnspvayrknpdnaipiksw

KGTPE
   |.
lsdps
subfamily_FCP1_pd Subfamily FCP1 152-254 7.9e-07 21.3 In-house 42-143 (146) alignment 
Range on Protein: 152-254
Range on HMM: 42-143/146.0
GWRTKKRPFLANFLESCVMELGLELVVFSESQVAEAMLLIdkMDPKQCI-QYRLYKPHMRYVDGEPVKDLDW-LNRDLSKVIVIDDKpEQVRKHKDNVLR
 . .|.|| |..|||.      | .. ... . ||..  |  .||.. . . |.          . .|.|.  ...| | |..|||. |.| ....|...
vyyvklRpnlkefleklsklyelhiytmgtraYaeqiaki..lDpekklfserilsrdelldassktkklkklfptddsmvviiDDr.edvWnfaenlik

VRPFK
|.|.|
vkpyk