Gene PAPL-3 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP084_AA protein Get Run
MbreP084_AA_109-332 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 111-333 1.3e-52 170.5 In-house 3-189 (189) alignment 
Range on Protein: 111-333
Range on HMM: 3-189/189.0
ADFGLDNDVSMETLLQLAAADAVDALILGGDFAYDFKDNHSAVGNAFMNTLEPFVSRKPFMPAPGNHEAHdGSFQQYTRRFEGVarnigkhshS--Nsnf
.|.| ..  |..|||. ..|...|..|  ||.||. |....||.. |||..||..|. |.| ..|||| .  .|..|..||.           |  .   
gDlgvseaaslatllkeeeaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesd.snfsaykkrfsmp.........skne...

YYSYDVGLIHFIAIDTEVGQLVGffekldmkqvyewynetqasiypfqpEEQLQWLEADLQRATaNRDVVPWIIMYGHKGWHMDYQ-PDKHnDLKPQLVT
.||.|.| .|||...|||   .|                          .||..|||.||..|. ||.  ||||..||...... .  |.. . . .||.
wYsfdygpvhfislstevdfslg..........................seqykWLekdLkean.nrkktpwiivmgHrPmYcsnkdeddc.tkeetlvr

N--FTGFTRLAEQYQVDLMLCGHLHIYQ
.  .... .| ..|.|||.|.|| |.|.
kglresledllykykvdlalsgHeHsYe
PAPL 110-225 9.8e-22 70.0 In-house 3-118 (194) alignment 
Range on Protein: 110-225
Range on HMM: 3-118/194.0
LADFGLDNDVSMETLLQLAAADAVDALILGGDFAYDFKDNHSAVGNAFMNTLEPFVSRKPFMPAPGNHEAHDgSFQQYTRRFEGVARNIGKHSHSNSNF-
..|.| .|  |...| . .. . .||... ||.||. ....  .|  ||. .||.....|.| ||||||..   |..|..||.   .. |.. .|.|.  
fGDlGqtnasslkrlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeey.nfsnykarfsmpgseegesnssesgsn

YYSYDVGLIHFIAIDTE
.||....  |||.. .|
sysfetesvhfivlsse
PAPL 245-332 3.1e-16 52.1 In-house 110-194 (194) alignment 
Range on Protein: 245-332
Range on HMM: 110-194/194.0
YNETQASIYPFQPEEQLQWLEADLQRATANRDVVPWIIMYGHKGWHMDYQPDKHNDlkpQLVTNFTGFTRLAEQYQVDLMLCGHLHIY
.. .. | .    |.. |. . ....| .||...||||..||. .    . .. ..   .  . ....  |  .|.|||.|.|| | |
vhfivlsseedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdkddck...ekakmlaaledllykygVDlvlaGHeHsY
Metallophos Calcineurin-like phosphoesterase 106-332 7.7e-15 48.7 Pfam-A 2-200 (200) alignment 
Range on Protein: 106-332
Range on HMM: 2-200/200.0
RIVFLADFGLDNDVS---METLLQLAAADAVDALILGGDFAYDFKDNHSAVGNAFmNTLEPFVSRKPFMPAPGNHEAHDGSFQQ-YTRRFEGVARNIGKH
||....| ....|..   .. ||..||   .|... .||. .  ..     ...  . ....   .|.....|||| . | .    .    . .| ....
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalld.ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglang

SHSNSNFyysydvglihfiaidtevgqlvGffEKLDMKQVYEWYNETQASIYPFQPEEQLQWLEADLqratANRDVVPWIIMYGHKGWHMD-YQPDKHnd
. . .|                       .  ..| . ..  ...     ....  .|. .. .. |     .|  |...|  .| ... . .  |..  
eeeyenl......................k..itllttsgelyglsglypllgdsaqeeqleeflal....plralvdgkilltHgplsssggsgddi..

lkPQLVTNFTGFTRLAEQYQVDLMLCGHLHIY
       .   .  | |.|.||| |.|| | .
..gselfgpdalekllekygvdlvlrGHtHkp
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 406-429 2.4e-07 22.4 Pfam-A 30-53 (62) alignment 
Range on Protein: 406-429
Range on HMM: 30-53/62.0
SANYGFGVLNAVNHTHLQWRWQET
...||.. |..||.|||.| . ..
esdyGysrltvvNrthLhwefvrs