Gene PAPL-9 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily PAPL
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP090_AA protein Get Run
MbreP090_AA_218-474 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP5_pd Subfamily ACP5 220-471 9.6e-48 154.6 In-house 1-189 (189) alignment 
Range on Protein: 220-471
Range on HMM: 1-189/189.0
IFGDMGVYTYNNMDWLLDDVKAQRIDFIVHLGDHAYNVAQDSGLRGDGYFNAFQPILTKIPWVPVLGNHEYYDgdEFNRFlnqtygvtlgdippahptsh
.|||.||.. .... ||.. .|...|.|.|.|| ||.......  .| ..|...|. .|.|.. ..||||. .  .|. .                    
vfgDlgvseaaslatllkeeeaneldliihvGDlaYalkakneavwdefmnlieplaskvPymvsiGnhesds..nfsay....................

insyiaigstlAQAVKGTSKTSrYYSVDVGQVHVISLDLNVYYFDTelvfrKPMLDWLRADLEAASqNRATVPWIIVNAHQPLYCSSVTMGENssSLWEF
            . .. .||.. .||.|.|.||.|||. .|...       .....||..||..|. ||.. |||||..|.|.|||. . ..   .  | 
...........kkrfsmpskne.wYsfdygpvhfislstevdfslg.....seqykWLekdLkean.nrkktpwiivmgHrPmYcsnkdeddc..tkeet

WYD-QsngenpgtfrgctgtgifpvevSRLDLEALFREFDVDLFFAGHEHDYE
    .                       |  || |. ...|||...|||| ||
lvrkg......................lresledllykykvdlalsgHeHsYe
Metallophos Calcineurin-like phosphoesterase 217-470 1.9e-19 63.7 Pfam-A 2-200 (200) alignment 
Range on Protein: 217-470
Range on HMM: 2-200/200.0
KFAIFGDMGVYTYNN---MDWLLDDVKAQRIDFIVHLGDHAYNVAQDSGLRGDGYfNAFQPILTKIPWVPVLGNHEYYDGDEFNRFLNQTYGVTLGDIPP
.....||..   . .   . .||.  .  ..|....|||  .     |. ... . .  ...| .||.....||||.. |.... ||. ...   |  . 
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalld.ylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglang

AHPTSHInsyiaigstlaqavkgtsktsryysvDvgqVHVISLDLNVYYFDTELVFRKPMLDWLRADLEAASQNRATVPWIIVNAHQPLYCSSVTMGENs
  ...                            .   .  .     .|. . .  ....   .   . ..|  .|| |...|. .|.||..|  .     
eeeyenl..........................k...itllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi.

sslwefwydqsngenpgtfrgctgtgiFPVEVSRLDLEALFREFDVDLFFAGHEHDY
                           . .. ..  || |... .||| . ||.| .
...........................gselfgpdalekllekygvdlvlrGHtHkp
PAPL 219-302 3e-17 55.4 In-house 1-84 (194) alignment 
Range on Protein: 219-302
Range on HMM: 1-84/194.0
AIFGDMGVYTYNNMDWLLDDVKAQRIDFIVHLGDHAYNVAQDSGLRGDGYFNAFQPILTKIPWVPVLGNHEYYDGDEFNRFLNQ
|.|||.|  .....  | .... . .|.|.|.|| ||.  ....  ||....  .|. ...|.  . ||||.    . ... ..
avfGDlGqtnasslkrlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaasvpymvapGNHEeeynfsnykarfs
Metallophos_C Iron/zinc purple acid phosphatase-like protein C 502-561 3.8e-13 41.0 Pfam-A 2-62 (62) alignment 
Range on Protein: 502-561
Range on HMM: 2-62/62.0
GVVHFVTGAGGApHLDKFGD-AGPFTRIQLSAWGYGRVTAT-QEEFVYEHVLNSNGTVFDRV
. || |.||.|. .|.|| .   ...... | .||.|.|.  ...  .|.| ...|.|.|..
ApvhIvvGaAGn.glskfskpqpewsafresdyGysrltvvNrthLhwefvrsddgqvlDsf
PAPL 340-409 1.2e-11 37.1 In-house 91-161 (194) alignment 
Range on Protein: 340-409
Range on HMM: 91-161/194.0
TS-RYYSVDVGQVHVISLDLNVYYFDTELVFRKPMLDWLRADLEAASQNRATVPWIIVNAHQPLYCSSVTM
..  ... .  .... .   ..... .|  . .    . . ... |..||. .||||| .|.|.|||. . 
gesnssesgsnsysfetesvhfivlsseedvkekseqyewleedlakvnRsktPWiivmgHrpmYcsnkdk
PhoD PhoD-like phosphatase 155-259 5.7e-11 33.0 Pfam-A 47-148 (453) alignment 
Range on Protein: 155-259
Range on HMM: 47-148/453.0
GITKEYTETSNASRHYFMHfVVFPDLTPSRSYFFRVRGGARSTWSSTFNFTSLySGEQKNETKFAIFGDMGV-YTYnnMDWLLDDVKAQRIDFIVHLGDH
 . .. | . ...| | .. | . .| |...||.|.| . ... | . ... |  ... .. ..|..... .   |  .  . . ......||..|||| 
rvvrsgtvlatserdytvk.vevtgLepgqeyfYrfraeegesespvGrtrTl.peaaveslrlavvSCsnyeqGy..fnayrelaekedlDfvlhlGDy

AYNVAQ
 |. ..
iYeyge
Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 217-504 1.7e-09 29.9 Pfam-A 2-138 (156) alignment 
Range on Protein: 217-504
Range on HMM: 2-138/156.0
KFAIFGDMGVyTYNNMDWLLDDVkaQRIDFIVHLGDhaynvA--QdsglrgdgyfNAFQPILTKIPWVPVLGNHEYYDgdeFNRFL---Nqtygvtlgdi
|.||..|.     .... .|.|.  ...|.|.|.||        .          ... . | .||   | |||.. .   ..  |              
kiaiiSDlHg.nldaleavledi..kevdlilhaGD.....lvep..........eevvelledipvlavrGnhDeae...lpkelavel..........

ppahptshinsyiaigstlaqavkgtskTSRYYSVDVGQVHVISL-----Dlnvyyfdtelvfrkpmldwlradleaasqnratvpwiivnahqplycss
                            ..... ..... .|. .     .                                                 
............................llaaaaleiegdrvllvhgtpls.................................................

vtmgenssslwefwydqsngenpgtfrgctgtgifpVEVSRLDLEALFREFDVDLFFAGHEHDYESiyavmngtvvnkcdagsTTPGNCTFTNPSGVV
                                    |. |. .|..|..| ..||.| || | ..                  .. |. .. ||  |.
....................................vqsseeelaellkeagadlvflGHtHkpkv.................ekrggtlvvnpGsvg
ACP5 222-292 3.9e-07 21.9 In-house 5-82 (198) alignment 
Range on Protein: 222-292
Range on HMM: 5-82/198.0
GDMGV---YTYNNMDWL-LDDVKAQRIDFIVHLGDHAYNVAQDS--GL-RGDGYFNAFQPILTKIPWVPVLGNHEYYD
||.|    | ....     . .. . |||.. |||  |.   .|       . . . ..  ....||. |||||.|..
GDwGrkgeynqsavakqmgkvaekldidfvlslGDnfyddGvtsvddprfkesfekiytakslqvpWyvvlGNHDyrg