Gene ACP5-2 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily ACP5
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP093_AA protein Get Run
MbreP093_AA_36-257 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PAPL_pd Subfamily PAPL 38-258 1.9e-92 300.3 In-house 2-212 (212) alignment 
Range on Protein: 38-258
Range on HMM: 2-212/212.0
LLGDWGGQDAAPYAEVGQLATVPGLTAVVTQVNAQLALLLGDNFYSSGIHsDEHDARFVETFEQVYNSSVLeAIPYYVIAGNHDHKGNVSAQIAYSQLSS
.||||||...|||... | |..  |..|.....||..| ||||||..|.. |..|||| ||||.|.....| ..|.||.|||||.|||||||||||.||.
vlgDwGgleeapyttaaqeavakelgkvaeeleaqfvlalGDnfYekGvk.dvddarfketfedvftaesl.qvpwyvvagnHDykGnvsaqiaYsklsk

RWHFDDYYYKKSFVFSPSserNMTIDIIFIDTVLLAGNSDDleDKfgtLPGPIDADWAETQWSWIQASLRDSTADYLFTAGHYPVWSGCSHGPTDILVDR
||.|...||.||| .. |   |.|.....||||||.|.|||  .|   | ||.|...||.||.|....|..|.||||..|||||||| ..||||.|||.|
rWkfpslyytksfkipds...natvqlvlidtvllcgksdd..lk...legpvdvslaeeqwawleeeLkaseadylivaGhypvwsvaehGptkiLvkr

LKPMLEQYGATGHLSGHDHCL
|||.||.| .|..||||||.|
LkPlLekynvtaylsGhDhnl
ACP5 37-257 1.2e-54 177.0 In-house 2-198 (198) alignment 
Range on Protein: 37-257
Range on HMM: 2-198/198.0
VLLGDWGGQDAAPYAEVGQlatvpGLTAVVTQVNAQLALLLGDNFYSSGIHSdEHDARFVETFEQVYNSSVLeAIPYYVIAGNHDHKGNVSAQIAYSQLS
...||||....... .| .      .. |... ...  | |||||| .|..| ..| || |.||..|... |  .|.||..||||..|||||||.|.. |
lvvGDwGrkgeynqsavak.....qmgkvaekldidfvlslGDnfyddGvts.vddprfkesfekiytaksl.qvpWyvvlGNHDyrgnvsaqieyakrs

SRWHFDDYYYKKSFVFspssernmtidiifiDTVLLAGNSDdlEDKFGTLPGPIDADWAETQWSWIQASLRDSTADYLFTAGHYPVWSGCSHGPTDILVD
 ...|  ..|..|. .               ... |  ...  ..|  .  .. . . ||.|..|....|..||||... .||.||.| ..||.|. ||.
kdsrfpslryslskke...............vvtelftekk..deksdqrevaerekyaeeqlkwlekalakstadwkiVvGHhpvySigehgdtkelve

RLKPMLEQYGATGHLSGHDHC
||.|.|..|... .|.|||||
rllpllkkykvdaYlnGHdHc
Metallophos Calcineurin-like phosphoesterase 37-257 2e-15 50.6 Pfam-A 4-199 (200) alignment 
Range on Protein: 37-257
Range on HMM: 4-199/200.0
VLLGDWGGQDAAPYaevgQlaTVPGLTAVVTQVNAQLALLLGDNFYSSGIHSDEHDARFvetfeqVYNSSVLEAIPYYVIAGNHDHKGNVSAQIAYSQLS
...||..|. . ..    .  ..  | ..  . ...| | |||....    | ... .        .   .|. ||.... |||. ..  ||  ..   .
lvigDlHgglddle....d..lllillkiaaeekpdlvlflGDlvdrgdwssetlalld......ylvlklllpipvfllrGNHesdpgnsaygflleql

SRWHFDDYYYKKSFVFspssernmtidiifiDtvLLAGNSDDLEDKFGTLPGPIDADWAETQWSWIQASLRDSTADYLFTAGHYPVWSGCSHGPT----D
...   ...... .                 .     ..  .       | .  . . .| |. .  | .  . .|. .  .| |..|   .| .    .
kdlrglangeeeyenl...............k..itllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddigsel

ILVDRLKPMLEQYGATGHLSGHDHC
   | | . ||.|| .  |.||.|.
fgpdalekllekygvdlvlrGHtHk
subfamily_ACP5_pd Subfamily ACP5 57-258 4.2e-12 38.4 In-house 20-188 (189) alignment 
Range on Protein: 57-258
Range on HMM: 20-188/189.0
AtvpgltavvTQVNAQLALLLGDNFYSSGIhsdeHDARFVETFEQVYNsSVLEAIPYYVIAGNHDHKGNVSAQiaysqlSSRWHFD------DYYYKKSF
.          . ...|.. .||  |  .     ....  ..| .. . ..   .|| |..|||... |.||       ..|..         . |..  
e.........eaneldliihvGDlaYalka....kneavwdefmnlie.plaskvPymvsiGnhesdsnfsay......kkrfsmpsknewYsfdygpvh

VFSPSSERNMTIDiifidtvllagnsddledkfgtlpgpidadwaETQWSWIQASLRDS----TADYLFTAGHYPVWSGCSHGP---------TDILVDR
. | |.| . . .                                ..|..|... |..     . ......|| |..   ...          .. |...
fislstevdfslg................................seqykWLekdLkeannrkktpwiivmgHrPmYcsnkdeddctkeetlvrkglres

LKPMLEQYGATGHLSGHDHCL
| ..|..|.    ||||.|. 
ledllykykvdlalsgHeHsY
PAPL 49-154 4e-08 25.6 In-house 13-107 (194) alignment 
Range on Protein: 49-154
Range on HMM: 13-107/194.0
PyaevgqlatVPGLTAVVTQVNAQLALLLGDNFYSSGIHSDEHDARFVETFEQVYNSsvleaIPYYVIAGNHDHKGNVSAQIAYSQLSSRWHFDDYYYKK
          .. |.. ... . .. |..||  |  . .. .   .|..  |.. .|     .|| |..|||... | |.. |... ..... . .....
s.........lkrlqketqkgkydailhvGDlaYaddeqnewdgdefmrqieplaas.....vpymvapGNHEeeynfsnykarfsmpgseegesnsses

S---FVFSP
.   . |. 
gsnsysfet